Reishi Mushroom Extract: Nature’s Adaptogen Powerhouse from a Trusted GMP Producer
1. What’s Reishi Mushroom Extract?
Reishi mushroom extract, derived from the basidiomycete fungus Ganoderma lucidum (Lingzhi), represents a pinnacle of adaptogenic natural dietary supplements. This concentrated bioactive formulation captures the mushroom’s potent triterpenes (ganoderic acids), polysaccharides (beta-glucans), and peptidoglycans via superior extraction methodologies. Revered for millennia in Conventional Chinese language Medication (TCM) because the “Mushroom of Immortality,” fashionable science validates its position in supporting holistic wellness, significantly immune modulation and stress response homeostasis.
2. Suministro de productos, propiedades químicas e identificación
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Suministro botánico: Ganoderma lucidum (Karst.) fruiting our bodies, sustainably cultivated.
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Major Bioactives:
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Triterpenes: Ganoderic acids A, C, D, F, H, Ok, and so on. (accountable for bitter style, key adaptogens).
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Polisacáridos: Beta-(1→3),(1→6)-D-glucans, heteropolysaccharides (main immunomodulators).
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Peptidoglycans, Proteins (Ling Zhi-8), Sterols, Nucleotides.
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CAS: 90045-38-8
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Método molecular (MF): Varies (Advanced combination; e.g., Ganoderic Acid A: C₃₀H₄₄O₇)
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Peso molecular (PM): Varies (e.g., Ganoderic Acid A: 504.7 g/mol)
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EINECS: Not particularly assigned; sometimes falls below 289-879-2 for sure mushroom extracts.
3. What Constitutes the Finest Reishi Extract? Key Specs
Choosing premium reishi extract calls for scrutiny throughout a number of parameters:
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Key Parts & Efficiency: Go for extracts standardized to essential markers:
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Polisacáridos: ≥ 30% (UV-Vis Spectrophotometry)
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Triterpenes: ≥ 6% (HPLC-UV)
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Ganoderic Acid Equal: ≥ 1.5% (HPLC-UV)
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Eficacia y cumplimiento: Backed by scientific analysis supporting construction/operate claims: helps wholesome immune system operate, promotes mobile antioxidant defenses, aids in managing physiological stress responses, helps cardiovascular wellness. Compliance Be aware: Statements adhere to DSHEA tips; not meant to diagnose, deal with, treatment, or forestall any illness.
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Origen: Sourced from pristine cultivation areas (e.g., China, Korea, licensed natural farms most well-liked).
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Utilización: Usually 500mg – 2000mg each day, typically in capsules, tablets, powders, or liquid tinctures. Finest taken with meals.
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Goal Demographics: Adults searching for immune assist, stress resilience, antioxidant safety, and general vitality enhancement. Notably related for people in high-stress environments.
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Contraindications & Security: Usually Acknowledged As Secure (GRAS) at really helpful dosages. Potential gentle unwanted effects embrace dry mouth/throat, GI upset, dizziness, or rash. Contraindicated:
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People with bleeding issues or taking anticoagulants (warfarin, aspirin) or antihypertensive medication (potential interplay).
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Pre/post-surgery sufferers (discontinue 2 weeks prior).
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Being pregnant and lactation (inadequate security information).
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Consumo diario: Scientific research typically make the most of 1.5g – 9g each day of dried mushroom equal. For concentrated extracts (e.g., 10:1), 150mg – 900mg each day is frequent. Seek the advice of a healthcare supplier for personalised dosing.
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Adulteration Dangers: Guarantee suppliers present complete Certificates of Evaluation (CoA) verifying authenticity and absence of fillers (starch, maltodextrin) or undisclosed mycelium/grain base.
4. Introducing Shaanxi Zhonghong Investment Technology Co., Ltd.: Your Premium Plant Extract Associate
Como un vertically built-in GMP-certified producer con 28 years of bioactives experience, Shaanxi Zhonghong is a pacesetter in high-purity plant extract options. We specialize within the superior extraction, isolation, and purification of botanicals for international markets.
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Competencias básicas:
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Rigor científico: Collaboration with 5 universidades de élite fuels our Más de 20 tecnologías patentadas y entrada a una biblioteca de compuestos internacionales patentada.
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Infraestructura de vanguardia: GMP-compliant manufacturing traces equipado con HPLC, UPLC, GC-MS y RMN superconductora garantizar Requisitos de pureza que superan las normas comerciales en 20%+. Nuestro laboratorio de control de calidad de última generación ensures batch-to-batch consistency.
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Alcance internacional: Servicio Más de 80 países throughout Asia, Europe, and the Americas, we offer Opciones de ingredientes botánicos personalizados to multinational nutraceutical manufacturers, beauty formulators, useful meals & beverage producers, and analysis establishments.
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Portafolio de productos: Plant Extract Powders, Natural Energetic Elements para Beauty Uncooked Supplies, Practical Meals Components, Beverage Components, Suplementos dietéticos, Colorantes naturales, Edulcorantes, y Intermedios farmacéuticos.
5. Well being Advantages: Mechanisms & Proof
Reishi’s adaptogenic results stem from synergistic bioactivity:
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Inmunomodulación: Beta-glucans bind macrophage/dendritic cell receptors (Dectin-1, TLRs), enhancing phagocytosis, NK cell exercise, and balanced cytokine manufacturing (IL-1β, TNF-α, IL-6, IFN-γ).
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Ejercicio antioxidante: Triterpenes scavenge ROS/RNS, upregulate endogenous antioxidants (SOD, GSH), and inhibit lipid peroxidation through Nrf2 pathway activation.
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Adaptogenic/Neuroprotective Results: Modulates HPA axis exercise, doubtlessly lowering cortisol overproduction. Might promote neuronal well being through BDNF assist and inhibition of MAO.
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Asistencia cardiovascular: Triterpenes inhibit angiotensin-converting enzyme (ACE), promote vasodilation, and should assist wholesome lipid metabolism.
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Fronteras del análisis: Ongoing research discover its position in metabolic well being, microbiome interactions, and particular bioactive compound isolation (e.g., extremely purified ganoderic acids for focused functions).
6. Consejos de utilización
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Standardized Powder: 500mg – 2000mg each day, sometimes divided doses. Combine into capsules, tablets, useful meals, or drinks.
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Liquid Extracts/Tinctures: Observe product-specific dosage (typically 1-2 mL, 1-3 instances each day).
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Optimum Timing: With meals to reinforce absorption and reduce potential GI discomfort.
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Combos sinérgicos: Typically paired with different adaptogens (Ashwagandha, Rhodiola) or immune supporters (Turkey Tail, Vitamin C).
7. Crucial Precautions
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Interacciones farmacológicas: Crucially keep away from concurrent use with anticoagulants (warfarin, heparin, clopidogrel), antiplatelets (aspirin), antihypertensives, immunosuppressants, or diabetes medicines with out strict medical supervision. Monitor for bruising/bleeding.
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Surgical procedure: Discontinue use no less than 2 semanas earlier than any scheduled surgical process.
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Circunstancias autoinmunes: Use with excessive warning or keep away from (e.g., RA, MS, lupus) – seek the advice of doctor.
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Estar embarazada/amamantando: Not really helpful on account of lack of sturdy security information.
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Alergia: Potential for mushroom allergy. Discontinue if hypersensitivity happens.
8. Product Specification & Certificates of Evaluation (CoA)
Clase | Mercancías | Especificación | Eche un vistazo a la metodología |
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Residuos de pesticidas | Clorpirifos | ≤ 0,01 ppm | GC-MS/MS |
Cipermetrina | ≤ 0,05 ppm | GC-MS/MS | |
Diclorvos | ≤ 0,01 ppm | GC-MS/MS | |
Pesticidas completos | Meet USP <561> / EP 2.8.13 | – | |
Metales pesados | Plomo (Pb) | ≤ 1,0 ppm | ICP-MS |
Arsénico (As) | ≤ 1,0 ppm | ICP-MS | |
Cadmio (Cd) | ≤ 0,5 ppm | ICP-MS | |
Mercurio (Hg) | ≤ 0,1 ppm | ICP-MS | |
Microbiológico | Dependencia microbiana cardiovascular completa | ≤ 10³ UFC/g | USP <61> |
Whole Yeast & Mildew Depend | ≤ 10² UFC/g | USP <61> | |
Escherichia coli | Ausente en 1g | USP <62> | |
Salmonela especies | Ausente en 10g | USP <62> | |
Estafilococo áureo | Ausente en 1g | USP <62> | |
Aflatoxinas (B1, B2, G1, G2) | ≤ 5 ppb (Whole) | HPLC-FLD |
*Extra Specs: Loss on Drying (≤ 8%), Ash (≤ 5%), Solvent Residues (Meet ICH Q3C), Purity (Polysaccharides ≥ 30%, Triterpenes ≥ 6% – HPLC/UV).*
9. Superior Manufacturing Course of
Our reishi extract is produced below stringent GMP protocols:
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Sourcing & ID: Premium natural G. lucidum fruiting our bodies authenticated through macroscopic/microscopic analysis & DNA barcoding.
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Preprocesamiento: Meticulous cleansing, drying (lyophilization/low-temp airflow), and milling to optimum particle measurement.
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Multi-stage Extraction: Usando proprietary dual-phase extraction (e.g., scorching water for polysaccharides adopted by ethanol for triterpenes) utilizing GMP-grade solvents.
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Purificación: Sequential steps together with adsorción de resina macroporosa, membrane filtration (extremely/nanofiltration), and centrifugal partition chromatography (CPC) for selective compound isolation.
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Enfocar: Low-temperature vacuum evaporation y secado por aspersión (with service like maltodextrin or acacia) to yield wonderful, secure powder. Liofilización choices obtainable for heat-sensitive compounds.
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Normalización: Exact mixing to realize assured bioactive marker ranges (Polysaccharides, Triterpenes).
10. Various Software Eventualities
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Nutracéuticos y suplementos dietéticos: Capsules, tablets, softgels, gummies, powders for immune, stress, and antioxidant assist.
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Comidas y bebidas prácticas: Fortified juices, teas, coffees, vitality bars, soups, confectionery.
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Cosmecéuticos: Serums, lotions, masks concentrating on anti-aging (antioxidant), soothing (anti-inflammatory), and pores and skin barrier enhancement.
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Pet Dietary supplements: Supporting immune well being and vitality in companion animals.
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Analysis Elements: For pharmacological, immunological, and biochemical research.
11. Strong High quality Management (QC)
Nuestro 300+ level QC system asegura distinctive purity, security, and efficacy:
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Afirmación de identificación: HPTLC, FTIR, DNA Authentication.
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Efficiency & Purity: HPLC-UV/DAD/ELSD for ganoderic acids profile; Espectrofotometría UV-Vis (Phenol-Sulfuric Acid) for polysaccharides; HPLC-CAD/ELSD for sugars profile; Disolventes residuales by GC-FID/HS-GC-MS per ICH Q3C.
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Gestión de contaminantes: ICP-MS for heavy metals; GC-MS/MS y LC-MS/MS for >400 pesticide residues; HPLC-FLD for mycotoxins; rigorous pruebas microbiológicas per USP/EP/JP.
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Bodily Parameters: Particle measurement distribution (Laser Diffraction), Bulk/Tapped Density, Flowability, Moisture (Karl Fischer), Ash Content material.
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Estabilidad: Actual-time & accelerated ICH stability research (25°C/60percentRH, 40°C/75percentRH) guaranteeing shelf-life claims (sometimes 24 months).
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Documentación: Completo Documentación GMP, full traceability from uncooked materials to completed items, and detailed Certificates of Evaluation (CoA) for each batch.
12. Packaging & International Logistics
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Embalaje principal: Meals-grade polyethylene liners adentro double Kraft paper luggage (25kg web). Choices: Foil luggage (1kg, 5kg) for enhanced moisture/oxygen barrier; small-quantity vacuum packs.
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Embalaje secundario: Sturdy cartons on pallets, shrink-wrapped.
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Almacenamiento: Cool (<25°C), dry (<60% RH), ventilated warehouse. Keep away from direct daylight.
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Duración: 24 meses from manufacturing date below really helpful storage.
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Logística Internacional: Environment friendly export documentation (C/O, Well being Certs, MSDS). Dependable sea/air freight companions guaranteeing well timed international supply. Opciones de cadena de frío obtainable for delicate extracts.
13. Analysis, Innovation & Business Challenges
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Análisis profundo del mecanismo: Ongoing analysis elucidates exact molecular targets (e.g., particular TLR isoforms, Nrf2-Keap1 pathway modulation) and intestine microbiota interactions.
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Extraction Innovation: Growth of inexperienced extraction methods (p.ej, subcritical water extraction, enzyme-assisted extraction, ultrasound/microwave enhancement) for increased yields and decrease environmental influence. AI-driven course of optimization.
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Novel Supply Programs: Encapsulation (liposomes, nanoparticles) to enhance bioavailability of poorly soluble triterpenes.
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Scientific Translation: Want for bigger, longer-term RCTs confirming particular well being advantages in outlined populations. Standardization challenges persist on account of advanced chemical profiles.
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Sostenibilidad: Making certain moral wildcrafting practices and scaling sustainable cultivation strategies for premium biomass.
14. Often Requested Questions (FAQ)
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Q: What makes your Reishi Mushroom Extract superior?
A: Nuestro GMP-certified reishi extract apalancamientos proprietary dual-extraction know-how garantizando excessive efficiency (>30% polysaccharides, >6% triterpenes), ultra-low contaminant ranges verified by HPLC and ICP-MS, and is manufacturing unit direct for assured greatest bulk worth. We provide especificaciones personalizadas to fulfill your formulation wants. -
Q: Is your extract appropriate for vegan dietary dietary supplements?
A: Completely. Our natural plant extract powder is 100% plant-derived, free from animal merchandise, GMOs, and customary allergens, making it ideally suited for vegan complement manufacturing. -
Q: Can I get a free pattern natural extract earlier than bulk ordering?
A: Sure! We encourage potential companions to request free samples to judge our high quality. Contact us through e-mail or our web site to receive your complimentary reishi extract pattern. -
Q: What’s the standard lead time for bulk reishi extract powder?
A: For normal specs, lead time is 15-25 days after order affirmation. Custom-made natural extract orders might require barely longer for course of optimization and QC. Manufacturing unit direct provide ensures effectivity. -
Q: Are you a licensed natural plant extract provider?
A: We provide each typical and licensed natural reishi mushroom extract choices. Our natural merchandise are licensed by acknowledged our bodies (e.g., USDA NOP, EU Natural) – please specify your requirement. -
Q: Do you provide customized extraction companies for particular triterpene profiles?
A: Sure, as a number one productor de extractos naturales, customization is a core power. We tailor extraction parameters (solvent ratio, temperature, time) and purification steps to focus on particular ganoderic acid profiles or polysaccharide fractions per your technical necessities.
15. The place to Purchase & Request Samples
Supply premium Reishi Mushroom Extract Powder straight from the GMP manufacturing unit!
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For Bulk Inquiries, Customized Specs, and FREE Samples:
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Correo electrónico: liaodaohai@gmail.com
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Sitio web: https://www.aiherba.com
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¿Por qué elegirnos? Manufacturing unit Direct Pricing, Unmatched Purity (HPLC Verified), Customized Formulation Experience, International Logistics Assist, y 28 Years of Botanical Excellence.
16. Conclusión
Reishi mushroom extract stands as a scientifically validated adaptogen, providing multifaceted assist for immune resilience, stress response, and general vitality. Partnering with a technologically superior, GMP-certified producer like Shaanxi Zhonghong Investment Technology Co., Ltd. is paramount for securing high-efficacy, contaminant-free, and constantly standardized extract. Our dedication to cutting-edge extraction, rigorous QC exceeding pharmacopeial requirements, and customizable options positions us because the premier proveedor internacional for nutraceutical, beauty, and useful meals innovators. Contact us at this time to debate your particular reishi extract wants and request your complimentary pattern.
17. References (Examples – Seek the advice of for Full Listing)
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Wachtel-Galor, S., Yuen, J., Buswell, J. A., & Benzie, I. F. F. (2011). Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In Natural Medication: Biomolecular and Scientific Elements (2nd ed.). CRC Press/Taylor & Francis.
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Batra, P., Sharma, A. Ok., & Khajuria, R. (2013). Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (increased Basidiomycetes): a bitter mushroom with wonderful well being advantages. Worldwide Journal of Medicinal Mushrooms, *15*(2), 127–143.
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Sanodiya, B. S., Thakur, G. S., Baghel, R. Ok., et al. (2009). Ganoderma lucidum: a potent pharmacological macrofungus. Present Pharmaceutical Biotechnology, *10*(8), 717–742.
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Xu, Z., Chen, X., Zhong, Z., et al. (2011). Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor actions. The American Journal of Chinese language Medication, *39*(01), 15–27.
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USP-NF (United States Pharmacopeia – Nationwide Formulary). Related Monographs (<202>, <561>, <2023> and so on.).
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European Pharmacopoeia (Ph. Eur.). Related Monographs (2.8.13, 2.2.58, 2.4.16 and so on.).
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