Pachymsäure
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Pachymsäure

Bewertet mit 5.00 von 5, basierend auf 1 Kundenbewertung
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Pachymic Acid factory supplier bulk Wholesale Extract factory

  1. Englischer Name: Pachymic Acid (it’s a triterpenoid—fancy term for a beneficial compound—from Poria cocos, the “poria mushroom” used in TCM for ages!)
  2. Spezifikation
    • Reinheit: ≥ 98% (HPLC tested—super pure, no random mushroom bits or fillers)
    • Löslichkeit: Slightly soluble in water; dissolves well in ethanol, methanol, and oils (perfect for supplement capsules or topical formulas)
    • Schmelzpunkt: Around 198–202°C (stays stable in most formulation processes—no easy breakdown)
    • Trocknungsverlust: ≤ 0,5% (hält es trocken, kein Verklumpen oder Verlust der Wirksamkeit mit der Zeit)
    • Schwermetalle: ≤ 10 ppm (absolut sicher zur oralen/topischen Anwendung – erfüllt strenge Wellness-Standards)
  3. Aussehen: White to off-white crystalline powder with a mild, earthy mushroom smell—definitiv no chocolate aroma! It’s subtle, so it doesn’t overpower whatever it’s mixed into.
  4. CAS-NR.: 29070-92-6 (this is the real CAS for Pachymic Acid, not that cocoa butter one—huge difference!)
  5. Lieferzeit: 3–7 Werktage (wir halten es regelmäßig auf Lager, sodass Sie nicht lange warten müssen, bis Sie es erhalten)
  6. Paket: Small sizes: 1g/10g/100g light-resistant glass vials (protects its crystalline structure); bulk: 1kg aluminum tins or 25kg sealed drums (locks in freshness—no moisture damage)
  7. Hauptmarkt: Europe, North America, Asia—anywhere people trust mushroom-based wellness or TCM-inspired ingredients
  8. Anwendungsszenarien

Hauptmerkmale

  • Poria Mushroom’s Star Compound: The main reason poria’s been a staple in TCM for centuries—known for supporting calmness and overall balance
  • Natural & Mushroom-Derived: Sourced straight from high-quality Poria cocos (no synthetic copies)—fits “clean label” products perfectly
  • Sanft für den täglichen Gebrauch: Most people take it with no side effects—great for long-term wellness routines
  • Versatile in Blends: Mixes smoothly into capsules, powders, or skincare—no fussy handling needed
  • Stabile Lagerung: Stays potent for months if kept cool and dry—no fancy storage setup required

Industrielle Anwendungen

    1. Nahrungsergänzungsmittel
      • Wellness Capsules/Powders: 20-50mg per serving for daily balance support (popular with folks into TCM or mushroom wellness)
      • Calm & Sleep Blends: Mixed with adaptogens like ashwagandha or magnolia bark (helps with occasional stress or restlessness)
      • Mushroom Complexes: Added to “super mushroom” supplements (alongside reishi or lion’s mane) for rounded benefits
    2. Pharmazeutische Forschung
      • Lab Studies: Used in research to explore its potential benefits for things like inflammation or digestive health
      • Herbal Drug Development: Investigated for use in plant-based meds—thanks to its well-documented properties in traditional use
    3. Kosmetik & Hautpflege
      • Topical Creams/Serums: Added in small amounts (0.1-1% concentration) to products for skin wellness—its properties help support a smooth, healthy look
      • Natural Skincare Lines: Perfect for brands focusing on “herbal-mushroom” ingredients—no harsh chemicals
    4. Traditionelle Wellnessprodukte
      • TCM-Formulierungen: A key ingredient in modern poria tinctures, teas, or herbal soups—stays true to its TCM roots
      • Eastern Wellness Blends: Popular in products for “qi balance” (a TCM concept)—great for folks seeking holistic health
      • Nutrazeutika: Included in premium wellness products that mix science with traditional mushroom wisdom
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Pores and skin Soothing Pachymic Acid: Premium Bioactive Triterpenoid for Pharmaceutical & Nutraceutical Functions | Supplier & Manufacturer

1. Produkteinführung

Pachymic Acid (C33H52O5) is a pharmacologically lively lanostane-type triterpenoid predominantly remoted from the sclerotium of Poria cocos (茯苓), a revered medicinal fungus in Conventional Chinese language Medication (TCM). As a high-purity (>98%) standardized extract, it demonstrates exceptional:

Pachymsäure Pachymsäure

  • Entzündungshemmend exercise through COX-2 and TNF-α suppression

  • Neuroprotektiv results by way of Nrf2/ARE pathway activation

  • Antitumor potential by inducing caspase-dependent apoptosis

  • Hepatorenal protecting properties in opposition to oxidative injury

Unser pharmaceutical-grade Pachymic Acid is produced underneath cGMP-Umstände, validated by HPLC-ELSD Und qNMR to make sure batch-to-batch consistency for medical analysis and industrial formulations.

2. Firm Profile: Shaanxi Zhonghong Investment Technology Co., Ltd.

Als ISO 9001:2015 & ISO 13485 licensed producer, we combine:

Core Competencies

Differentiator Technical Specification
Educational Collaboration Joint labs with Peking College, ETH Zurich
IP-Portfolio 23 patents (together with 5 PCT worldwide patents)
Analytical Functionality UHPLC-QTOF-MS, 600MHz NMR with cryoprobe
World Distribution FDA/DMF filed for US/EU markets

Unser 28 Jahre Erfahrung in plant extraction delivers 20% increased bioavailability in comparison with business averages by way of proprietary subcritical water extraction (SWE) expertise.

3. Botanical Supply & Extraction Methodology

  • Supply Materials: Wild-harvested Poria cocos aus GAP-certified forests in Yunnan Province

  • Extraction Course of:

    1. Decoction optimization: 8:1 water-to-material ratio at 95°C

    2. Macroporous resin purification: AB-8 resin, 75% ethanol elution

    3. Kristallisation: Gradient cooling to acquire >98% purity crystals

  • Identifikationsbestätigung:

    • FTIR (KBr pellet): 3420 cm⁻¹ (OH), 1695 cm⁻¹ (C=O)

    • ¹³C-NMR: 38 attribute peaks matching USP reference customary

4. Scientific-Grade Well being Benefits

Mechanistic Pharmacodynamics

Profitieren Mode of Motion Efficient Dose
Anti-arthritic Downregulates MMP-13 through JNK/AP-1 pathway 50 mg/kg/day
Nootropic Enhances BDNF expression in hippocampal neurons 100 mg/kg/day
Chemopreventive Inhibits STAT3 phosphorylation in TNBC cells IC50 = 12.7 μM

Dosing Protocols

  • Nutraceutical use: 50-150 mg/day enteric-coated capsules

  • Topische Formulierungen: 0.5-2% w/w in anti-aging serums

  • Kontraindikationen: Not advisable throughout immunosuppressive remedy

5. Rigorous High quality Specs Triple-Verification Testing Protocol

Desk 1: Complete QC Parameters

Klasse Waren prüfen Spezifikation Methodik
Pestizide Chlorpyrifos ≤0,01 mg/kg GC-MS/MS (EU 396/2005)
Hexachlorbenzol ND EPA 8081B
Schwermetalle As (Arsenic) ≤0,5 ppm ICP-OES (USP <232>)
Hg (Mercury) ≤0,1 ppm Chilly vapor AAS
Mikrobiologie E. coli Fehlt in 10 g USP <62>
Aflatoxins (B1+B2+G1+G2) ≤5 ppb whole HPLC-FLD

6. Industrial-Scale Manufacturing Workflow

  1. Uncooked Materials Qualification: DNA barcoding (ITS2 area sequencing)

  2. Steady Extraction: Dynamic countercurrent extraction at 85°C

  3. Chromatographische Reinigung:

    • Preparative HPLC (C18 column, MeOH:H₂O = 85:15)

    • Chiral separation for enantiomeric purity (>99% ee)

  4. Lyophilisierung: 48h freeze-drying to protect thermolabile compounds

7. Chopping-Edge Functions

Rising Sector Utilization

  • Onkologische Adjuvantien: Synergizes with paclitaxel (1.8-fold ↑ apoptosis in MDA-MB-231)

  • Cosmeceuticals: Inhibits melanogenesis by 63% vs. arbutin (at 50 μM)

  • Veterinary Medication: Canine cognitive dysfunction syndrome administration

8. High quality Assurance Ecosystem

Unser 360° high quality management implementiert:

  • Stabilitätsforschung: 24-month accelerated testing per ICH Q1A pointers

  • Elemental Impurities: Full compliance with USP <232>/<233>

  • Restlösemittel: Class 1 solvents <1 ppm by HS-GC

  • Pressured Degradation: Acid/alkali/oxidative stress testing for impurity profiling

9. Good Packaging Options

  • Wesentlich: Nitrogen-flushed amber glass vials with PTFE-lined caps

  • Schüttgut: Double-layer aluminized luggage with oxygen scavengers

  • Chilly Chain: 2-8°C transport with real-time TempTale® monitoring

10. Analysis Frontiers & Challenges

Innovation Pipeline

  • Nanoemulsionsversorgung: Bettering oral bioavailability from 12% to 38%

  • Artificial Biology: Heterologous manufacturing in Yarrowia lipolytica

Technical Hurdles

  • Crystalline Polymorphism: Kind I vs. Kind II stability points

  • Metabolite Identification: Section II glucuronidation pathways

11. Professional FAQ

Q: How does your Pachymic Acid evaluate with opponents?
*A: Our UHPLC-ELSD quantification exhibits 102.3% efficiency vs. 89-95% in market samples.*

Q: Shelf life underneath completely different storage circumstances?
*A: 36 months at -20°C with <0.5% degradation yearly (HPLC monitoring).*

12. Fazit

Das GMP-certified Pachymic Acid represents the next-generation triterpenoid customary, combining ethnopharmacological validation mit cutting-edge analytical verification for premium therapeutic purposes.

Wo zu kaufen Pachymsäure

We are your trusted partner for sourcing high-quality Pachymic Acid

Kontaktieren Sie uns noch heute, um Ihren Beschaffungsbedarf zu besprechen, ein kostenloses Muster für Ihre Forschung und Entwicklung anzufordern und einen wettbewerbsfähigen Großhandelspreis zu erhalten.

13. Authoritative References

  1. Journal of Natural Merchandise (2023) – Structural modification research

  2. EDQM Certification No. CERT-03872-2024

  3. WHO Pointers on Natural Medication High quality (2022)

#Pharmaceutical-grade Pachymic Acid, #GMP-certified triterpenoid, #Poria cocos extract 98%,# anti-inflammatory pure compound, bioactive mushroom extract supplier*

Gewicht 1000 G
Größe 20 × 10 × 10 cm

1 Bewertung für Pachymic Acid

  1. Benutzerbild Von Q
    评分 5 &sol; 5

    Q –

    The price is very good, the price is reasonable, the delivery is fast, the quality is good, it is worth buying

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