, , , , ,

Spermidine

Spermidine

  1. English Ngalan: Spermidine
  1. Espesipikasyon
    • Kaputli: ≥ 98% (HPLC)
    • Pagkamatunaw: Soluble in water, ethanol, and chloroform
    • Melting Level: 22 – 25°C
    • Pagkawala sa Pagpauga: ≤ 0.5%
    • Bug-at nga Metal: ≤ 10 ppm
  1. Tan-awa: Colorless to pale yellow liquid or crystalline strong, with a slight amine-like odor; no chocolate-related traits
  1. CAS NO.: 124-20-9
  1. Panahon sa pagpanguna: 3 – 7 ka Adlaw sa Trabaho
  1. Pakete deal: 1g, 10g, 100g glass vials; 1kg aluminum containers; 25kg sealed drums (below inert fuel)
  1. Panguna Merkado: Europe, North America, Asia, and so on.
  1. Software Mga sitwasyon

yawe Mga kapilian

  • Autophagy Inducer: Recognized to stimulate autophagy, a mobile kurso sa that removes broken mga bahin
  • Polyamine Properties: Belongs to the polyamine household, supporting cell kalamboan and survival
  • Antioxidant Resulta: Could tabang giputol balik oxidative stress in cells
  • Bioaktibo: Naturally current sa lainlain mga pagkaon like wheat germ, soybeans, and mushrooms
  • Kalig-on: Lig-on below gidumala storage; delikado sa sobra temperatures and robust oxidizing brokers

Pamatigayon Mga gimbuhaton

  1. Dietary Mga suplemento sa pagkaon
    • Anti-Ageing Pagporma: Included in mga suplemento sa pagkaon (kasagaran 1 – 5mg per serving) for potential age-related kaayohan tabang
    • Mobile Kaayohan Mga baligya: Gigamit sa blends concentrating on mobile pag-atiman and performance
    • Wellness Mga suplemento sa pagkaon: Added to formulations pagbaligya heneral kaayohan and vitality
  1. Biomedical Pagtuki
    • Laboratory Pagpanukiduki: Utilized in pagtuki on autophagy, cell biology, and growing older processes
    • Droga Growth: Investigated for potential roles in therapeutic mga katuyoan kauban to neurodegenerative mga sakit and longevity
  1. Mga Kosmetiko ug Pag-atiman sa Panit
    • Anti-Ageing Mga baligya: Added to serums and mga lotion (0.01 – 0.1% focus) for potential skin-rejuvenating resulta
    • Mobile Tabang Mga pormulasyon: Included in baligya concentrating on pores ug panit cell kaayohan ug iuli
  1. May katuyoan Mga pagkaon
    • Fortified Mga pagkaon: Added to health-oriented mga pagkaon like cereals and kalagsik bars to spice up dietary content material
    • May katuyoan Mga ilimnon: Integrated into wellness drinks for his or her bioactive nga mga kabtangan

Unlock Mobile Renewal: Your Full Information to Premium Spermidine

1. What Precisely IS Spermidine?
Ever really feel like your physique wants a inside reset button? That is the place spermidine is available in. Overlook difficult jargon for a second – consider it as your cells’ pure spring cleaner. Discovered inside each residing cell (yours included!), this unimaginable polyamine molecule orchestrates a significant course of known as autophagy. That is your physique’s method of clearing out outdated, broken mobile parts, making area for contemporary, wholesome ones. As we age, our pure spermidine ranges drop, which is why supplementing is creating such a buzz within the longevity and wellness world. It’s like giving your cells a much-needed tune-up!

2. Sourcing & Science: The Constructing Blocks

  • Supply: Whereas spermidine happens naturally in meals like aged cheese, wheat germ, soy merchandise, and mushrooms, high-purity dietary supplements are usually derived via superior extraction from premium plant sources like wheat germ or particular legumes. This ensures constant efficiency you merely cannot get from food plan alone.

  • Pagkaila sa Kemikal:

    • CAS: 124-20-9

    • MF (Molecular Components): C₇H₁₉N₃

    • MW (Molekular nga Timbang): 145.25 g/mol

    • EINECS: 204-689-0

  • Key Properties: Spermidine is a white or barely yellow crystalline powder. It’s extremely soluble in water and displays its organic exercise primarily by activating key mobile pathways concerned in renewal.

3. Selecting the BEST Suplemento sa Spermidine: Your Purchaser’s Information
Slicing via the complement noise is hard. Right here’s what really issues for a top-tier spermidine product:

  • Panguna nga sangkap: Pangitaa ang high-purity spermidine trihydrochloride (spermidine 3HCl). This secure salt type ensures optimum bioavailability – that means your physique can truly paggamit kini.

  • Confirmed Well being Benefits (Science-Backed):

    • Mobile Renewal Champion: Powers autophagy, clearing mobile particles linked to getting old and dysfunction.

    • Coronary heart Well being Supporter: Promotes cardiovascular operate and wholesome blood strain.

    • Cognitive Operate: Rising analysis suggests potential for safeguarding mind well being and reminiscence.

    • Longevity Pathways: Prompts mobile processes related to selling a more healthy lifespan.

    • Hair & Pores and skin Vitality: Could assist more healthy hair development and pores and skin resilience.

  • Pagsunod: Make sure the product is manufactured in cGMP-certified amenities (like ours!) and undergoes rigorous pagsulay sa ikatulo nga partido for purity, efficiency, and security. Ask for the COA (see beneath!).

  • Sinugdanan: Sourced from premium, traceable botanicals and reworked utilizing cutting-edge know-how.

  • Paggamit: Usually 1-3 mg day by day, taken within the morning. At all times comply with the particular product label directions.

  • Who It is For: Adults in search of mobile well being assist, wholesome getting old methods, cardiovascular wellness, or cognitive upkeep. Notably related for these over 30 as pure ranges decline.

  • Essential Precautions & Aspect Results:

    • Seek the advice of Your Physician First: Particularly if pregnant, breastfeeding, taking drugs, or have underlying well being situations.

    • Begin Low: Start with the bottom dose to evaluate tolerance.

    • Potential Aspect Results: Typically well-tolerated. Uncommon, delicate stories embody digestive upset. Excessive doses might doubtlessly work together with sure drugs (like some antidepressants or blood strain medication) – therefore the physician seek the advice of!

    • High quality Issues: Low-quality sources would possibly include impurities. At all times select respected suppliers like Zhonghong.

4. Why Belief Zhonghong for Your Spermidine?
Sa Zhonghong Funding Know-how Co., Ltd. (Shaanxi), we’re not simply one other tigsuplay; we’re your innovation accomplice in bioactive compounds. For 28 ka tuig, we have pioneered the science of plant extraction, serving world leaders in prescription drugs, nutraceuticals, and analysis.

  • Dili hitupngan nga Scientific Rigor: We co-innovate with 5 elite nga unibersidad in devoted labs, holding 20+ patente and curating a globally distinctive compound library. We resolve complicated extraction challenges others cannot.

  • Slicing-Edge Precision: Our funding speaks volumes: HPLC (Sobra-Episyente nga Liquid Chromatography)Extremely-Conducting NMR (Nuclear Magnetic Resonance). This is not simply commonplace testing – it’s how we assure purity requirements exceeding trade norms by 20%+. You get what the label guarantees, each single batch.

  • Actually International Attain: Atong bulto ug custom-made options reliably serve 80+ international locations throughout Asia, Europe, and the Americas. From pakyaw distributors to revolutionary factories, we energy your merchandise.

  • Finish-to-Finish Experience: From sustainable botanical sourcing to superior extraction, stringent QC, and world logistics – we management the method. This implies constant high qualitytraceability, ug reliability you may construct your model on.

5. Deep Dive: Product Specification & High quality Assurance (COA)
Transparency is non-negotiable. Each Zhonghong spermidine batch ships with a complete Certificates of Evaluation (COA). Right here’s what we vigilantly check for:

High quality Management Desk: Zhonghong Spermidine Specs

KlaseTake a look at ParameterSpecification RestrictTake a look at MethodologyWhy It Issues
Identification & PuritySpermidine 3HCl Content material≥ 98.0%HPLCEnsures efficiency & effectiveness
Pesticide Residues (Examples)
Mga chlorpyrifos<0.01 ppmGC-MS/MSEnsures security from dangerous agri-chemicals
Cypermethrin<0.01 ppmGC-MS/MS
Glyphosate<0.05 ppmLC-MS/MS
Bug-at nga Metal
Tingga (Pb)< 1.0 ppmICP-MSPrevents poisonous metallic accumulation
Arsenic (As)<0.5 ppmICP-MS
Cadmium (Cd)<0.5 ppmICP-MS
Mercury (Hg)<0.1 ppmICP-MS / CV-AAS
Microbiology
Complete Plate Depend<1000 CFU/gUSP <61>Confirms product is free from dangerous microbes
Yeast & Mildew<100 CFU/gUSP <61>
E. coliDestructiveUSP <62>
Salmonella spp.DestructiveUSP <62>
Staph. aureusDestructiveUSP <62>

Our QC Dedication:
High quality is not a checkpoint; it is our DNA. At Zhonghong, our cGMP-compliant high quality management system governs each step. Beginning with rigorously audited uncooked supplies, we make use of state-of-the-art nga instrumento sa pagtuki (HPLC, GC-MS/MS, LC-MS/MS, ICP-MS) for unparalleled precision. Our stability testing packages guarantee efficiency all through shelf-life. Past assembly pharmacopoeial requirements (USP, EP), we implement stringent inside specs, usually exceeding world benchmarks. Each analytical methodology undergoes exhaustive validation (accuracy, precision, specificity, LOD/LOQ, linearity, robustness) per ICH tips. Our devoted QC crew, educated in present Good Manufacturing Practices, paperwork every little thing meticulously, guaranteeing full traceability from uncooked materials to completed spermidine bulk powder. We function below a sturdy High quality Administration System (QMS) encompassing doc management, deviation administration, CAPA, and common audits. This relentless focus ensures that each gram of Zhonghong spermidine delivers constant purity, security, and efficacy to your well being complementpormulasyon sa katahum, o analysis utility.

6. Superior Manufacturing: Precision from Seed to Spec
Our spermidine is not simply extracted; it is meticulously engineered:

  1. Pagkuha: Premium, non-GMO botanical sources (e.g., choose wheat germ) from trusted world companions.

  2. Pagkuha: Using proprietary low-temperature strategies ug inexperienced solvents to softly launch spermidine whereas preserving its bioactivity and minimizing environmental influence.

  3. Pagputli: Multi-stage purification cascades together with chromatography (affinity, ion-exchange) obtain distinctive purity (>98%), successfully eradicating sugars, proteins, and different plant matrix parts.

  4. Crystallization ug Pagpauga: Managed crystallization yields high-purity spermidine 3HCl crystals, adopted by mild lyophilization (freeze-drying) o pag-spray sa pagpauga below inert ambiance to make sure stability and stop degradation.

  5. Mixing & Standardization: Exact mixing ensures uniform efficiency all through the batch.

  6. Pagputos: Nitrogen-flushed, light-resistant, multi-layered barrier packaging (HDPE drums, aluminum luggage) protects towards moisture, oxygen, and lightweight degradation.

7. The place Spermidine Shines: Key Functions

  • Nutraceuticals & Dietary Dietary supplements: Standalone capsules, tablets, powders, or complicated longevity/anti-aging formulations.

  • Useful Meals & Drinks: Fortified well being drinks, bars, cereals (requires solubility/stability options).

  • Mga kosmetiko: Premium anti-aging serums, lotions, lotions focusing on mobile renewal for pores and skin and hair well being.

  • Pharmaceutical Analysis: Reference commonplace, energetic ingredient in scientific research exploring autophagy-related ailments (neurodegeneration, cardiovascular).

  • Tutorial Analysis: Instrument for finding out autophagy mechanisms, getting old biology, and mobile signaling pathways.

8. Past Fundamentals: Analysis & Innovation Frontiers

  • Mga Mekanismo sa Kaayohan: Intense analysis focuses on spermidine’s exact molecular targets past autophagy induction (e.g., lipid metabolism, mitochondrial operate, epigenetic regulation, irritation modulation) and its interaction with intestine microbiota.

  • Medical Functions: Ongoing trials discover its therapeutic potential for Alzheimer’s, Parkinson’s, coronary heart failure, metabolic syndrome, and even most cancers prevention/adjuvant remedy.

  • Supply Improvements: Enhancing bioavailability through novel supply methods (liposomes, nanoparticles, phospholipid complexes) is a key trade focus. Zhonghong actively develops custom-made supply options.

  • Sustainable Manufacturing: Creating enzymatic synthesis or microbial fermentation as scalable, sustainable options to plant extraction is a significant problem and alternative. Zhonghong invests in inexperienced chemistry R&D.

  • Synergistic Blends: Researching optimum mixtures with different bioactives (e.g., resveratrol, NMN, NAD+) for enhanced results.

9. FAQ: Your Spermidine Questions Answered

  • Q: What’s the advisable day by day dose?

    • A: Analysis usually makes use of 1-3 mg day by day. Begin low (e.g., 1mg) and seek the advice of your healthcare supplier for personalised recommendation primarily based in your targets and well being standing.

  • Q: Are there any meals sources wealthy in spermidine?

    • A: Sure! Aged cheese (particularly cheddar, blue), wheat germ, soybeans, mushrooms, legumes, and entire grains include spermidine, although ranges differ considerably. Dietary supplements provide a dependable, concentrated dose.

  • Q: Can I take spermidine with different dietary supplements or drugs?

    • A: Potential interactions exist (e.g., with MAO inhibitors, sure blood strain meds). At all times seek the advice of your physician or pharmacist earlier than beginning spermidine, particularly if on medicine.

  • Q: How lengthy does it take to note results?

    • A: Spermidine works on the mobile degree. Benefits like improved vitality or pores and skin/hair adjustments could also be delicate and gradual, usually observed over weeks or months of constant use. Autophagy advantages are steady.

  • Q: Is spermidine protected throughout being pregnant or breastfeeding?

    • A: Security hasn’t been conclusively established in these teams. Keep away from use or seek the advice of your OB/GYN first.

  • Q: How ought to I retailer spermidine powder?

    • A: Preserve in a cool, dry place (ideally 15-25°C/59-77°F) in its authentic hermetic, light-resistant container. Keep away from humidity and warmth. Bulk powder for manufacturing unit use requires particular storage situations – seek the advice of our crew.

  • Q: Do you provide free samples for formulation testing?

    • A: Sure! Among gitanyag libre nga pattern natural nga kinuha portions for certified custom-made natural nga kinuha inquiries and formulation growth. Contact us to debate your wants.

10. Able to Expertise Premium Spermidine?
Supply smarter, supply purer, supply with Zhonghong. As your trusted organic plant extract supplier ug spermidine producer, we assure:

  • Uncompromising Purity: Verified by our cutting-edge labs.

  • Scientific Backing: Leveraging 28 years of bioactive experience.

  • International Reliability: Seamless bulto provide to your manufacturing unit or lab worldwide.

  • Customized Options: Want a particular purity, particle dimension, or supply format? We excel at custom-made natural nga kinuha growth.

  • Clear Partnership: Detailed documentation, together with full COAs.

Involved in spermidine bulk powder? Wish to focus on a customized formulation? Want samples to check?

Contact Zhonghong Immediately!

  • E-mail: sales@aiherba.com o liaodaohai@gmail.com

  • Web site: www.aiherba.com

  • Key phrases for Your Search: spermidine tigsuplay, spermidine bulto, spermidine manufacturing unitpurchase spermidine, spermidine Wholesale, spermidine Extract manufacturing unit, spermidine bili, spermidine prodyuserlibre nga pattern natural nga kinuhaorganic plant extract suppliercustom-made natural nga kinuha.

11. Conclusion: Elevate Mobile Well being with Confidence
Spermidine represents a groundbreaking frontier in supporting mobile well being and longevity. Selecting a high-quality, scientifically validated supply is paramount to unlocking its full potential. Zhonghong Funding Know-how Co., Ltd. stands on the forefront of spermidine manufacturing, combining many years of experience, cutting-edge know-how, and an unwavering dedication to purity and security. Whether or not you are a formulator, wholesaler, researcher, or health-conscious model, accomplice with Zhonghong for premium spermidine that delivers on its promise. Expertise the Zhonghong distinction – the place science meets purity for optimum wellness.

12. References (Illustrative – Seek the advice of Particular Research)

  • Madeo, F., Eisenberg, T., Pietrocola, F., & Kroemer, G. (2018). Spermidine in well being and illness. Siyensiya, 359(6374). [DOI: 10.1126/science.aan2788]

  • Eisenberg, T., Abdellatif, M., Schroeder, S., et al. (2016). Cardioprotection and lifespan extension by the pure polyamine spermidine. Nature Drugs, 22, 1428–1438. [DOI: 10.1038/nm.4222]

  • Gupta, V. Okay., Scheunemann, L., Eisenberg, T., et al. (2013). Restoring polyamines protects from age-induced reminiscence impairment in an autophagy-dependent method. Nature Neuroscience, 16, 1453–1460. [DOI: 10.1038/nn.3512]

  • Pietrocola, F., Lachkar, S., Enot, D. P., et al. (2015). Spermidine induces autophagy by inhibiting the acetyltransferase EP300. Cell Dying & Differentiation, 22, 509–516. [DOI: 10.1038/cdd.2014.215]

  • United States Pharmacopeia (USP) Common Chapters: <61> Microbiological Examination, <62> Microbiological Exams, <233> Elemental Impurities.

  • Worldwide Council for Harmonisation (ICH) Pointers: Q2(R1) Validation of Analytical Procedures.

评价

目前还没有评价

Ang mga naka-log in ra nga mga kostumer nga nakapalit niini nga produkto mahimong magbilin usa ka pagsusi.

滚动至顶部

Pagkuha ug Quote & Sample

请在浏览器中启用JavaScript来完成此表单。

Pagkuha ug Quote & Sample