কুকারবিটাসিন

Cucurbitacin: Premium Manufacturer & World Supplier for Pharmaceutical and Analysis Functions | Aiherba

 Supply high-purity Cucurbitacin from Zhonghong, a number one প্রযোজক এবং বাল্ক সরবরাহকারী. Discover its analysis purposes, advantages, and request a বিনামূল্যে প্যাটার্ন to your R&D initiatives. Get a aggressive মূল্য quote immediately.

১. কুকারবিটাসিন কী?

Cucurbitacin is a category of extremely oxidized tetracyclic triterpenoids discovered primarily in vegetation of the Cucurbitaceae household, resembling pumpkins, gourds, and cucumbers. These compounds are famend for his or her intensely bitter style and important organic exercise. For বি২বি purchasers within the pharmaceutical and analysis sectors, Cucurbitacins (notably Cucurbitacin B, E, and I) characterize a high-value, potent lively ingredient for anti-cancer, anti-inflammatory, and different therapeutic analysis purposes. Partnering with a dependable Cucurbitacin producer is important for acquiring materials of constant purity and validated organic exercise.

2. সরবরাহ, রাসায়নিক বৈশিষ্ট্য এবং শনাক্তকারী

• পণ্য সরবরাহ: Extracted from varied Cucurbitaceae vegetation, with particular isoforms (e.g., Cucurbitacin B) typically sourced from একবালিয়াম ইলেটেরিয়াম (Squirting Cucumber) or Citrullus colocynthis.

• Main Lively Compounds: Cucurbitacin B, Cucurbitacin E, Cucurbitacin I, amongst others.

• Instance CAS Quantity: 6199-67-3 (Cucurbitacin B)

• Instance Molecular System (MF): C32H46O8 (Cucurbitacin B)

• Instance Molecular Weight (MW): 558.71 g/mol (Cucurbitacin B)

• আইনী আইন: Varies by particular Cucurbitacin sort.

3. Deciding on the Greatest Cucurbitacin: A Information for B2B Consumers and Researchers

জন্য বিশ্বব্যাপী pharmaceutical corporations, analysis establishments, and রপ্তানিকারক, the definition of “finest” hinges on exact standardization, verified organic exercise, and complete analytical documentation.

• মূল উপাদান এবং কার্যকারিতা: The very best grade Cucurbitacin is standardized to a selected isoform (e.g., 98%+ Cucurbitacin B). Its most researched properties embrace:

  • Potent Anti-Most cancers Exercise: Induces apoptosis and inhibits proliferation in varied most cancers cell traces by focusing on JAK-STAT3 and different signaling pathways. Observe: For analysis use solely; not for direct human consumption as a complement.

  • Sturdy Anti-Inflammatory and Immunosuppressive Results: Modulates inflammatory responses, making it a compound of curiosity for autoimmune illness analysis.

  • Purported Hepatoprotective Properties: Some isoforms are studied for his or her potential to guard liver cells.

  • (Compliant for analysis purposes, pharmaceutical intermediate use, and reference requirements.)

• উৎপত্তি এবং উচ্চ মানের: Our uncooked supplies are sourced from recognized botanical species and cultivated beneath managed situations to make sure a constant chemical profile.

• ব্যবহার এবং মাত্রা:

  • সাধারণ ব্যবহার: Predominantly utilized in pharmaceutical R&D as a reference commonplace, a constructing block for novel drug synthesis, and for in vitro and in vivo (animal mannequin) research. Not usually utilized in cosmetics or dietary dietary supplements on account of its efficiency and potential toxicity.

  • পরামর্শযোগ্য ডোজ: There isn’t any commonplace every day consumption for people. All dosing is very particular to analysis protocols. Our group supplies technical knowledge to tell your experimental design.

• প্রাসঙ্গিক দর্শক: Pharmaceutical R&D departments, educational analysis establishments, and biotechnology corporations engaged in oncology and immunology analysis.

• Notes & Aspect Results:

  • সতর্কতা: HANDLE WITH CARE. Cucurbitacins are extremely bioactive and might be poisonous if mishandled. They’re for analysis functions solely by certified professionals in laboratory settings. Not for meals, beauty, or complement use.

  • পার্শ্ব প্রতিক্রিয়া: Primarily based on analysis, excessive doses may cause extreme gastrointestinal misery and different systemic toxicities.

4. Why Associate with Zhonghong (Aiherba) as Your Cucurbitacin Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (World Advertising: Aiherba) একটি লাইসেন্সপ্রাপ্ত উচ্চ-প্রযুক্তি সংস্থা এবং একটি বিশ্বস্ত রপ্তানিকারক specializing within the synthesis, extraction, and purification of high-potency bioactive compounds for the worldwide বি২বি বাজার।

• বৈজ্ঞানিক উৎকর্ষতা: Our joint laboratories with 5 main universities and portfolio of 20+ patents enable us to deal with advanced purification challenges, providing Cucurbitacins of outstanding purity.

• অতুলনীয় উচ্চমানের ব্যবস্থাপনা: Our funding in superior tools like HPLC and Superconducting NMR ensures our Cucurbitacin purity requirements exceed typical business specs, which is vital for reproducible analysis outcomes.

• বিশ্ব B2B সম্প্রদায়: With 28 years of expertise, we provide ব্যক্তিগতকৃত elements and reference requirements to multinational pharmaceutical firms, পাইকারি distributors, and premier analysis establishments throughout 80+ nations.

• কারিগরি সহায়তা: We offer complete supporting documentation, together with detailed MSDS and analytical knowledge sheets, important to your regulatory and analysis compliance.

৫. বিস্তারিত পণ্যের স্পেসিফিকেশন (COA)

Each batch is accompanied by a complete Certificates of Evaluation (COA) to ensure it meets rigorous research-grade requirements.

৬. উচ্চমানের ব্যবস্থাপনার উৎপাদন কোর্স

The extraction of Cucurbitacin requires refined strategies on account of its advanced construction and low pure abundance. We make use of superior strategies, together with chromatographic separation and crystallization, to isolate particular Cucurbitacin isoforms from rigorously chosen plant materials.

আমাদের উচ্চমানের ব্যবস্থাপনা protocol is designed for research-grade actives. It begins with botanical authentication and is adopted by in-process testing at each vital step of the extraction and purification course of. Ultimate product evaluation utilizing Excessive-Efficiency Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) ensures exact standardization and confirms the molecular id of the compound. This multi-layered QC course of, performed in our state-of-the-art labs, ensures each batch delivers constant, dependable efficiency in your most delicate analysis purposes, making us a premier ব্যক্তিগতকৃত প্রাকৃতিক নির্যাস accomplice for the pharmaceutical business.

৭. আবেদনের পরিস্থিতি

Cucurbitacin is primarily utilized in superior analysis settings:

• Pharmaceutical R&D: As a lead compound in oncology drug discovery, a reference commonplace, and for mechanistic research on apoptosis.

• Tutorial Analysis: Utilized in cell biology and pharmacology departments to review cell signaling pathways (JAK/STAT, NF-κB) and inflammatory processes.

• জৈবপ্রযুক্তি: Investigated for growing focused most cancers therapies and novel anti-inflammatory brokers.

8. Analysis, Innovation, and Challenges

The first mechanism of Cucurbitacin B entails the inhibition of the JAK/STAT3 pathway, resulting in cell cycle arrest and apoptosis in most cancers cells. Present বিশ্লেষণ সীমানা concentrate on bettering its bioavailability and lowering systemic toxicity via novel drug supply techniques (e.g., nanoparticle encapsulation, conjugation). The principle সমস্যা is translating its potent in vitro exercise into protected and efficient scientific therapies. At Zhonghong, our উদ্ভাবন lies in growing extremely purified isoforms and supporting our বি২বি companions by offering the vital high-quality uncooked supplies wanted for his or her next-generation drug growth applications.

৯. প্রায়শই জিজ্ঞাসিত প্রশ্নাবলী – নিয়মিতভাবে অনুরোধ করা প্রশ্নাবলী

Q: What is the Minimal Order Amount (MOQ) for analysis functions?
A: MOQs range primarily based on the precise Cucurbitacin isoform and purity. We accommodate orders for research-scale portions. Contact us to debate your particular wants.

Q: Are you able to present customized purification to isolate a selected Cucurbitacin isoform?
উত্তর: অবশ্যই, আমরা ফোকাস করি ব্যক্তিগতকৃত প্রাকৃতিক নির্যাস options. Our superior know-how permits us to tailor our processes to isolate and purify particular isoforms per your analysis necessities.

Q: Do you provide samples for technique growth and validation?
উ: সম্পূর্ণরূপে। আমরা অফার করি বিনামূল্যে প্যাটার্ন প্রাকৃতিক নির্যাস supplies to certified analysis establishments and firms for analysis and testing functions.

Q: What packaging do you employ to make sure product stability throughout worldwide transport?
A: We use sealed, tamper-evident containers with desiccant to guard the product from moisture and contamination, making certain it arrives in optimum situation to your analysis.

Q: What documentation is supplied with worldwide orders?
A: We offer a full suite of paperwork together with Certificates of Evaluation (COA), Materials Security Knowledge Sheet (MSDS), Certificates of Origin, and industrial bill.

১০. বিনামূল্যে নমুনা কেনার এবং অনুরোধ করার জায়গা

এক নম্বর হিসেবে প্রযোজক এবং আন্তর্জাতিক সরবরাহকারী of high-potency plant extracts, we’re your trusted accomplice for sourcing research-grade Cucurbitacin.

Contact us immediately to debate your procurement wants, request a free pattern to your R&D, and get a aggressive wholesale worth.

• ইমেইল: sales@aiherba.com সম্পর্কে / liaodaohai@gmail.com

• ওয়েবসাইট: www.aiherba.com

১১. উপসংহার

জন্য বি২বি purchasers in pharmaceutical and superior analysis, Cucurbitacin represents a robust instrument for drug discovery and organic mechanism research. Deciding on a supplier with rigorous purification capabilities, analytical experience, and a deep understanding of compliance is paramount. Zhonghong (Aiherba) presents not only a product, however a dependable partnership, offering the high-purity, well-documented actives required to drive innovation in your labs, backed by almost three a long time of experience in bioactive compounds.

১২. তথ্যসূত্র

• Most cancers Analysis: Seminal research on the anti-cancer mechanisms of Cucurbitacin B through JAK/STAT3 inhibition.

• Journal of Medicinal Chemistry: Analysis on the structure-activity relationships of various Cucurbitacin analogs.

• Journal of Organic Chemistry: Research on the anti-inflammatory properties of Cucurbitacins.

• USP-NF Compendial Strategies for analytical testing.