Glutamik turşu
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Glutamik turşu

Glutamic Acid supplier bulk factory Wholesale buy Extract factory

  1. İngilis adı: Glutamic Acid; 2-Aminopentanedioic acid
  1. Spesifikasiya
    • Saflıq: Glutamic Acid ≥ 99.0% (HPLC)
    • Optical Purity: L – Glutamic Acid ≥ 99.0% (for chiral products), D – Glutamic Acid available for specific applications
    • Həlledicilik: Sparingly soluble in cold water (0.86 g/100 mL at 25°C), soluble in hot water and strong acids/alkalis; water – soluble salts (e.g., monosodium glutamate) have higher solubility
    • Hissəcik ölçüsü: Standard powder ≤ 150 μm; spray – dried powder ≤ 50 μm for better flowability
  1. Görünüş
    • Powder: White to off – white crystalline powder, odorless, slightly acidic taste
  1. CAS NO.：56 – 86 – 0 (L – Glutamic Acid); 6893 – 11 – 8 (D – Glutamic Acid)
  1. Təqdimat vaxtı: 3 – 5 Working Days
  1. Paket
    • 25 kg/drum (polyethylene bag inside cardboard drum), 1000 kg/super sack for bulk orders
  1. Əsas bazar: Global market, with significant demand in Asia (China, Japan), North America, and Europe
  1. Tətbiq Ssenariləri

Əsas Xüsusiyyətlər

  • Molekulyar Formula: C₅H₉NO₄
  • Ionization Behavior: Amphoteric compound with three ionizable groups (α – amino, α – carboxyl, and γ – carboxyl), pKa values: 2.19 (α – COOH), 4.25 (γ – COOH), 9.67 (α – NH₂)
  • Əsas Xüsusiyyətlər
    • Protein Building Block: One of the 20 standard amino acids, essential for protein synthesis in living organisms.
    • Neurotransmitter Precursor: In the human body, L – Glutamic Acid is a precursor to the neurotransmitter glutamate, crucial for nerve signal transmission.
    • Flavor Enhancer: Its sodium salt, monosodium glutamate (MSG), provides umami taste, widely used in the food industry.
    • Metabolic Intermediate: Involved in the Krebs cycle and nitrogen metabolism, playing a key role in energy production and amino acid balance.

Tətbiq Ssenariləri

1. Qida və İçkilər

  • Dadın Gücləndirilməsi:
    • As the raw material for monosodium glutamate (MSG), added to soups, sauces, snacks, and instant noodles at 0.1 – 1% concentration to enhance umami flavor.
    • Used in meat – based products, seasonings, and vegetarian dishes to improve taste.
  • Qidalanma Gücləndirilməsi:
    • Added to infant formulas, sports drinks, and nutritional supplements to increase protein content and support amino acid balance.
    • In baked goods, it can improve dough elasticity and shelf – life.

2. Əczaçılıq

  • Nutraceuticals and Supplements:
    • Capsules or tablets containing L – Glutamic Acid (500 – 1000 mg per serving) are sold for brain health support, as it aids in neurotransmitter synthesis and may improve cognitive function.
    • Used in amino acid infusion solutions for patients with nutritional deficiencies or recovering from surgery.
  • Dərman sintezi:
    • Serves as an intermediate in the synthesis of various drugs, such as anticonvulsants and antidepressants, due to its role in the nervous system.

3. Heyvan Yemi

  • Protein Source:
    • Added to livestock, poultry, and aquaculture feed at 0.5 – 2% to improve the amino acid profile, enhance growth performance, and increase feed efficiency.
    • In pet food, it helps meet the protein requirements of animals, especially during growth and recovery periods.

4. Kosmetika və Şəxsi Qulluq

  • Skin Moisturizer:
    • Incorporated into creams, lotions, and serums (0.5 – 2% concentration) to improve skin hydration, as it has water – binding properties.
    • Used in anti – aging products for its potential to stimulate collagen synthesis.
  • Saça Qulluq:
    • Added to shampoos and conditioners to strengthen hair fibers and improve hair elasticity.

5. Sənaye Tətbiqləri

  • Biodegradable Plastics:
    • As a raw material for the synthesis of poly(glutamic acid), which is used to produce biodegradable polymers for packaging materials.
  • Su müalicəsi:
    • Its derivatives can be used as chelating agents to remove heavy metals from water, binding to metal ions and facilitating their removal.

Aşkarlama üsulları

  • Yüksək Performanslı Maye Xromatoqrafiyası (HPLC):
    • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: 0.1% phosphoric acid – acetonitrile (95:5 v/v), Flow Rate: 1.0 mL/min, Detection Wavelength: 210 nm for quantification.
  • Ion – Exchange Chromatography:
    • Used for separating and analyzing different forms of glutamic acid (e.g., L – and D – isomers) based on their ionic properties.
  • Amino Acid Analyzer:
    • Specifically designed equipment that uses ion – exchange chromatography and post – column derivatization with ninhydrin to accurately measure the concentration of glutamic acid in complex samples.

Mənbə və Üstünlüklər

  • Təbii Mənbə: Produced by fermentation of carbohydrates (e.g., molasses, glucose) using microorganisms like Corynebacterium glutamicum.
  • Cost – Effective: Large – scale industrial fermentation processes ensure a stable and affordable supply.
  • Çox yönlü: Its wide range of applications from food to industrial sectors makes it a valuable commodity in the global market.

Tənzimləmə Uyğunluğu

  • ABŞ FDA: GRAS – listed for use as a flavor enhancer and nutrient in food products. Meets cGMP requirements for pharmaceutical – grade products.
  • AB Qaydaları: Approved as a food additive (E620 for glutamic acid and its salts) with specific usage limits in different food categories.
  • Çin NMPA: Permitted for use in food, pharmaceuticals, and animal feed, subject to strict quality control standards.
Kateqoriyalar: , , ,

The Complete Information to Glutamic Acid: Science, Benefits & Premium Sources | Supplier & Manufacturer

1. What is Glutamic Acid?

Glutamic acid (C₅H₉NO₄), a non-essential α-amino acid, is without doubt one of the 20 basic proteinogenic amino acids and the most ample excitatory neurotransmitter within the vertebrate central nervous system37. Naturally occurring as L-glutamic acid (the biologically lively type), it serves twin roles:

  • Metabolic gasoline: Key in mobile vitality manufacturing by way of the citric acid cycle

  • Neurochemical signaling: Mediates cognitive features like studying and reminiscence by NMDA/AMPA receptors310
    Found in 1866 by German chemist Karl Ritthausen, its flavor-enhancing property (umami) was recognized by Japanese scientist Kikunae Ikeda in 1908, resulting in monosodium glutamate (MSG) manufacturing3.

2. Supply, Chemical Properties & Specs

Təchizat:

  • Natural: Considerable in protein-rich meals (cheese, soy sauce, seafood, meat)14

  • Industrial: Fermentation of carbohydrates (e.g., sugarcane molasses) or hydrolysis of plant proteins like wheat gluten3

Chemical Profile:

Əmlak dəyər
CAS Quantity (L-isomer) 56-86-03
Molecular Formulation C₅H₉NO₄
Molekulyar Çəki 147.13 g/mol
EINECS 200-293-7
Melting Level 247–249°C
Həlledicilik 8.57 g/L (water), low in ethanol3
pKa Values 2.10, 4.07, 9.473
Key Options:

  • Exists as a zwitterion at physiological pH

  • Precursor to GABA (γ-aminobutyric acid), the first inhibitory neurotransmitter3

3. Well being Benefits, Dosage & Security

What is the “Greatest” Type?

  • L-glutamic acid (CAS: 56-86-0) is the biologically lively isomer, constituting >90% of high-purity dietary supplements38. D-glutamic acid (CAS: 6893-26-1) lacks metabolic exercise.

Sağlamlığın üstünlükləri və mexanizmləri:

  1. Neurological Well being:

    • Enhances synaptic plasticity for studying and reminiscence

    • Lowers blood ammonia, assuaging hepatic encephalopathy710

  2. Metabolic Assist:

    • Facilitates nitrogen transport for protein synthesis

    • Gücləndirir intestine integrity by fueling intestinal cells4

  3. Train Efficiency:

    • Will increase endurance and muscle restoration (dose: 4g/day)1

Each day Consumption & Security:

  • Böyüklər: 4000 mg/day as dietary complement1

  • Tibbi istifadə: As much as 30g/day for chemotherapy-induced mucositis (underneath medical supervision)4
    Faset Nəticələri:

  • Gentle: Facial flushing, nausea, diarrhea at excessive doses7

  • Əks göstərişlər: Renal impairment, lively ulcers10

4. Supply Chief: Shaanxi Zhonghong Investment Technology Co., Ltd.

kimi 28-year pioneer in bioactive compounds, Shaanxi Zhonghong integrates cutting-edge R&D with international provide chain excellence:

  • Scientific Limitations:

    • 20+ patents and unique compound libraries

    • Joint labs with 5 prime universities

  • Yüksək keyfiyyətli infrastruktur:

    • HPLC/UPLC & NMR spectrometry making certain purity >99% (20% above business requirements)

    • GMP-compliant fermentation and purification services

  • International Attain:

    • Provides 80+ nations throughout prescription drugs, nutraceuticals, and cosmetics25

Product Portfolio: Pharmaceutical-grade L-glutamic acid, plant extracts, pure sweeteners, and beauty actives.

5. Ciddi Məhsul Xüsusiyyətləri

Shaanxi Zhonghong’s L-glutamic acid exceeds worldwide pharmacopeial requirements (USP, FCC):

Desk 1: Heavy Metallic & Contaminant Limits

Sinif Parametr məhdudlaşdırmaq Texnikaya nəzər salın
Ağır metallar Qurğuşun (Pb) ≤1,0 ppm ICP-MS
Arsen (As) ≤1,0 ppm ICP-MS
Kadmium (Cd) ≤0,5 ppm ICP-MS
Merkuri (Hg) ≤0,1 ppm CVAAS
Mikrobiologiya Bütün Kardio Mikrobdan asılıdır ≤1,000 KFU/q USP <61>
E. coli 10 q-da yoxdur USP <62>
Pestisidlər DDT isomers ≤0,05 ppm GC-MS
BHC isomers ≤0,05 ppm GC-MS

6. Üstün İstehsalat Kursu

A 9-step cGMP workflow ensures premium high quality:

  1. Uncooked Materials Choice: Non-GMO sugarcane/molasses

  2. Fermentasiya: Microbial (Corynebacterium glutamicum) batch tradition

  3. Ayrılıq: Centrifugation and ultrafiltration

  4. Təmizləmə: Ion-exchange chromatography

  5. Kristallaşma: Vacuum-evaporative crystallization

  6. Qurutma: Spray drying → Free-flowing powder

  7. QC Testing: NMR identification affirmation, HPLC purity assay (>99%)5

7. Sənayedə Məqsədlər

  • Reçeteli dərmanlar: Hepatic coma remedy, IV diet7

  • Nutraceuticals: Sports activities dietary supplements, cognitive well being formulation

  • Meals & Beverage: MSG for umami taste, protein fortification

  • Kosmetika: Moisturizing brokers in dermal serums14

8. Kompromissiz Yüksək Keyfiyyətli İdarəetmə

Each batch undergoes 15+ checks by way of:

  • Chromatography: HPLC/UPLC for enantiomeric purity and residual solvents

  • Spectroscopy: NMR for structural validation, ICP-MS for heavy metals

  • Mikrobiologiya: USP-compliant pathogen screening
    Stability research (ICH Q1A) validate a 24-month shelf life at <25°C/65% RH5.

9. Qablaşdırma və Logistika

  • mayor: 25-kg food-grade kraft baggage with double PE liners

  • Saxlama: Cool (<25°C), dry circumstances; keep away from daylight

  • Nəqliyyat: International door-to-door supply (4–10 days) with pay as you go tariffs

10. FAQs: Glutamic Acid Demystified

Q: Is glutamic acid the identical as MSG?
A: MSG is the sodium salt of glutamic acid. Each happen naturally however MSG is used as a taste enhancer3.

Q: Can vegans use L-glutamic acid?
A: Sure—artificial or plant-fermented variants are vegan-friendly1.

Q: Does it trigger “Chinese language Restaurant Syndrome”?
A: No sturdy proof helps this fantasy. FDA and EFSA classify MSG/glutamate as GRAS37.

Q: Why select pharmaceutical-grade purity?
A: Reduces contaminants (e.g., D-isomers, heavy metals) making certain security for medical use8.

The place to Purchase

üçün high-purity L-glutamic acid (≥99% HPLC):

Nəticə

Glutamic acid’s twin position as a metabolic middleman and neurochemical makes it indispensable for well being and business. Shaanxi Zhonghong leverages 28 illik təcrübə, unmatched chromatography tech, və international compliance to ship premium L-glutamic acid. Associate with us for licensed, research-backed amino acid options.

İstinadlar

  1. JECFA. Glutamic Acid Monograph. WHO, 2023.

  2. EFSA Panel on Meals Components. Security of glutamic acid. EFSA Journal, 2010.

  3. Ritthausen, Ok. Discovery of glutamic acid. J Prakt Chem, 1866.

  4. KingNet Medical Database. Therapeutic makes use of of glutamic acid. 2024.

  5. Shandong Freda Biotech. Fermentation protocols. 2021.

  6. Zhonghong QC Guide. Analytical strategies for amino acids. 2023.

  7. Mattson, M. Glutamate signaling in mind improvement. Nat Rev Neurosci, 2008.

  8. NIH. D-amino acids in human physiology. PMC, 2020.

  9. BulkSupplements. L-glutamic acid security information. 2023.

  10. KingNet. Medical pharmacology of glutamic acid. 2024.

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