كوكوربيتاسين

Cucurbitacin: Premium Manufacturer & World Supplier for Pharmaceutical and Analysis Functions | Aiherba

 Supply high-purity Cucurbitacin from Zhonghong, a number one منتج و مورد بالجملة. Discover its analysis purposes, advantages, and request a نمط مجاني to your R&D initiatives. Get a aggressive يستحق quote immediately.

1. What is Cucurbitacin?

Cucurbitacin is a category of extremely oxidized tetracyclic triterpenoids discovered primarily in vegetation of the Cucurbitaceae household, resembling pumpkins, gourds, and cucumbers. These compounds are famend for his or her intensely bitter style and important organic exercise. For ب2ب purchasers within the pharmaceutical and analysis sectors, Cucurbitacins (notably Cucurbitacin B, E, and I) characterize a high-value, potent lively ingredient for anti-cancer, anti-inflammatory, and different therapeutic analysis purposes. Partnering with a dependable Cucurbitacin producer is important for acquiring materials of constant purity and validated organic exercise.

2. العرض والخصائص الكيميائية والمعرفات

• توريد المنتج: Extracted from varied Cucurbitaceae vegetation, with particular isoforms (e.g., Cucurbitacin B) typically sourced from Ecballium elaterium (Squirting Cucumber) or Citrullus colocynthis.

• Main Lively Compounds: Cucurbitacin B, Cucurbitacin E, Cucurbitacin I, amongst others.

• Instance CAS Quantity: 6199-67-3 (Cucurbitacin B)

• Instance Molecular System (MF): C32H46O8 (Cucurbitacin B)

• Instance Molecular Weight (MW): 558.71 g/mol (Cucurbitacin B)

• إينكس: Varies by particular Cucurbitacin sort.

3. Deciding on the Greatest Cucurbitacin: A Information for B2B Consumers and Researchers

ل في جميع أنحاء العالم pharmaceutical corporations, analysis establishments, and المصدرين, the definition of “finest” hinges on exact standardization, verified organic exercise, and complete analytical documentation.

• المكون الرئيسي والفعالية: The very best grade Cucurbitacin is standardized to a selected isoform (e.g., 98%+ Cucurbitacin B). Its most researched properties embrace:

  • Potent Anti-Most cancers Exercise: Induces apoptosis and inhibits proliferation in varied most cancers cell traces by focusing on JAK-STAT3 and different signaling pathways. Observe: For analysis use solely; not for direct human consumption as a complement.

  • Sturdy Anti-Inflammatory and Immunosuppressive Results: Modulates inflammatory responses, making it a compound of curiosity for autoimmune illness analysis.

  • Purported Hepatoprotective Properties: Some isoforms are studied for his or her potential to guard liver cells.

  • (Compliant for analysis purposes, pharmaceutical intermediate use, and reference requirements.)

• الأصل والجودة العالية: Our uncooked supplies are sourced from recognized botanical species and cultivated beneath managed situations to make sure a constant chemical profile.

• الاستخدام والجرعة:

  • الاستخدام النموذجي: Predominantly utilized in pharmaceutical R&D as a reference commonplace, a constructing block for novel drug synthesis, and for in vitro and in vivo (animal mannequin) research. Not usually utilized in cosmetics or dietary dietary supplements on account of its efficiency and potential toxicity.

  • Advisable Dosage: There isn’t any commonplace every day consumption for people. All dosing is very particular to analysis protocols. Our group supplies technical knowledge to tell your experimental design.

• المشاهدين المعنيين: Pharmaceutical R&D departments, educational analysis establishments, and biotechnology corporations engaged in oncology and immunology analysis.

• Notes & Aspect Results:

  • احتياطات: HANDLE WITH CARE. Cucurbitacins are extremely bioactive and might be poisonous if mishandled. They’re for analysis functions solely by certified professionals in laboratory settings. Not for meals, beauty, or complement use.

  • نتائج الجانب: Primarily based on analysis, excessive doses may cause extreme gastrointestinal misery and different systemic toxicities.

4. Why Associate with Zhonghong (Aiherba) as Your Cucurbitacin Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (World Advertising: Aiherba) هي مؤسسة مرخصة ذات تقنية عالية وموثوقة مصدر specializing within the synthesis, extraction, and purification of high-potency bioactive compounds for the worldwide ب2ب سوق.

• التميز العلمي: Our joint laboratories with 5 main universities and portfolio of 20+ patents enable us to deal with advanced purification challenges, providing Cucurbitacins of outstanding purity.

• إدارة عالية الجودة لا مثيل لها: Our funding in superior tools like HPLC and Superconducting NMR ensures our Cucurbitacin purity requirements exceed typical business specs, which is vital for reproducible analysis outcomes.

• مجتمع B2B العالمي: With 28 years of expertise, we provide شخصية elements and reference requirements to multinational pharmaceutical firms, بالجملة distributors, and premier analysis establishments throughout 80+ nations.

• المساعدة الفنية: We offer complete supporting documentation, together with detailed MSDS and analytical knowledge sheets, important to your regulatory and analysis compliance.

5. مواصفات المنتج التفصيلية (COA)

Each batch is accompanied by a complete Certificates of Evaluation (COA) to ensure it meets rigorous research-grade requirements.

6. دورة التصنيع وإدارة الجودة

The extraction of Cucurbitacin requires refined strategies on account of its advanced construction and low pure abundance. We make use of superior strategies, together with chromatographic separation and crystallization, to isolate particular Cucurbitacin isoforms from rigorously chosen plant materials.

ملكنا إدارة عالية الجودة protocol is designed for research-grade actives. It begins with botanical authentication and is adopted by in-process testing at each vital step of the extraction and purification course of. Ultimate product evaluation utilizing Excessive-Efficiency Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) ensures exact standardization and confirms the molecular id of the compound. This multi-layered QC course of, performed in our state-of-the-art labs, ensures each batch delivers constant, dependable efficiency in your most delicate analysis purposes, making us a premier مستخلص طبيعي مخصص accomplice for the pharmaceutical business.

7. سيناريوهات التطبيق

Cucurbitacin is primarily utilized in superior analysis settings:

• Pharmaceutical R&D: As a lead compound in oncology drug discovery, a reference commonplace, and for mechanistic research on apoptosis.

• Tutorial Analysis: Utilized in cell biology and pharmacology departments to review cell signaling pathways (JAK/STAT, NF-κB) and inflammatory processes.

• Biotechnology: Investigated for growing focused most cancers therapies and novel anti-inflammatory brokers.

8. Analysis, Innovation, and Challenges

The first mechanism of Cucurbitacin B entails the inhibition of the JAK/STAT3 pathway, resulting in cell cycle arrest and apoptosis in most cancers cells. Present حدود التحليل concentrate on bettering its bioavailability and lowering systemic toxicity via novel drug supply techniques (e.g., nanoparticle encapsulation, conjugation). The principle مشكلة is translating its potent in vitro exercise into protected and efficient scientific therapies. At Zhonghong, our ابتكار lies in growing extremely purified isoforms and supporting our ب2ب companions by offering the vital high-quality uncooked supplies wanted for his or her next-generation drug growth applications.

9. FAQ – Steadily Requested Questions

Q: What is the Minimal Order Amount (MOQ) for analysis functions?
A: MOQs range primarily based on the precise Cucurbitacin isoform and purity. We accommodate orders for research-scale portions. Contact us to debate your particular wants.

Q: Are you able to present customized purification to isolate a selected Cucurbitacin isoform?
أ: بالتأكيد، نحن نركز على مستخلص طبيعي مخصص options. Our superior know-how permits us to tailor our processes to isolate and purify particular isoforms per your analysis necessities.

Q: Do you provide samples for technique growth and validation?
أ: تمامًا. نحن نقدم مستخلص طبيعي بنمط حر supplies to certified analysis establishments and firms for analysis and testing functions.

Q: What packaging do you employ to make sure product stability throughout worldwide transport?
A: We use sealed, tamper-evident containers with desiccant to guard the product from moisture and contamination, making certain it arrives in optimum situation to your analysis.

Q: What documentation is supplied with worldwide orders?
A: We offer a full suite of paperwork together with Certificates of Evaluation (COA), Materials Security Knowledge Sheet (MSDS), Certificates of Origin, and industrial bill.

10. مكان شراء وطلب عينات مجانية

كرقم واحد منتج و المورد الدولي of high-potency plant extracts, we’re your trusted accomplice for sourcing research-grade Cucurbitacin.

Contact us immediately to debate your procurement wants, request a free pattern to your R&D, and get a aggressive wholesale worth.

• بريد إلكتروني: sales@aiherba.com / liaodaohai@gmail.com

• موقع إلكتروني: www.aiherba.com

11. الخاتمة

ل ب2ب purchasers in pharmaceutical and superior analysis, Cucurbitacin represents a robust instrument for drug discovery and organic mechanism research. Deciding on a supplier with rigorous purification capabilities, analytical experience, and a deep understanding of compliance is paramount. Zhonghong (Aiherba) presents not only a product, however a dependable partnership, offering the high-purity, well-documented actives required to drive innovation in your labs, backed by almost three a long time of experience in bioactive compounds.

12. المراجع

• Most cancers Analysis: Seminal research on the anti-cancer mechanisms of Cucurbitacin B through JAK/STAT3 inhibition.

• Journal of Medicinal Chemistry: Analysis on the structure-activity relationships of various Cucurbitacin analogs.

• Journal of Organic Chemistry: Research on the anti-inflammatory properties of Cucurbitacins.

• USP-NF Compendial Strategies for analytical testing.