Vitamin B12
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Vitamin B12

Vitamin B12 factory supplier bulk Wholesale Extract factory

  1. English Name: Vitamin B12 (also called cobalamin— it’s one of the B-vitamins, and the only one you can’t get from plants! The most common forms are cyanocobalamin (cheap, stable, for supplements) and methylcobalamin (active form, better for nerve health).
  1. Specification
    • Purity: ≥ 99% (HPLC tested—pharmaceutical/food grade, no fillers; supplement doses range from 100 mcg to 5,000 mcg per serving)
    • Solubility: Highly water-soluble (mixes easily in drinks, supplements, or fortified foods—dissolves clear, no clumps)
    • Moisture: ≤ 0.5% (keeps it dry, so it doesn’t cake up or lose potency—stable at room temp for years)
    • Heavy Metals: ≤ 1 ppm (ultra-safe for oral use, even for long-term daily intake—meets global vitamin standards)
    • Form: Fine red-pink powder (cyanocobalamin) or light yellow powder (methylcobalamin)—the color’s a dead giveaway it’s real!
  1. Appearance: For cyanocobalamin (most common)—bright red-pink fine powder with a mild, neutral aroma; for methylcobalamin—pale yellow powder. Definitely not a yellowish-white solid with chocolate scent! It has a subtle vitamin-like smell, no chocolate notes at all.
  1. CAS NO.: Depends on the form—cyanocobalamin is 68-19-9; methylcobalamin is 13422-55-4 (no single CAS for “Vitamin B12” since it has different active forms)
  1. Lead time: 3–7 Working Days (we stock both cyanocobalamin and methylcobalamin in bulk and small sizes—fast for supplement brands, vegan food makers, and pharmacies)
  1. Package:
    • Small sizes: 10g/100g amber glass jars (light-proof to protect the color/potency) or 30-count sublingual tablets (dissolve under the tongue for fast absorption)
    • Bulk: 25kg food-grade drums (lined with plastic—27 drums per tray; includes desiccants to keep moisture out and preserve the powder)
  1. Main Market: Global—North America (vegan supplements, senior multivitamins), Europe (fortified plant milks, breakfast cereals), Asia (energy drinks, B-complex supplements). Essential for vegans, seniors, and anyone with absorption issues (like gut problems).
  1. Applications & Main Benefits
    • Dietary Supplements
      • Vegan/Vegetarian Capsules: 1,000–5,000 mcg per serving (vegans can’t get B12 from plants—this fills the gap to prevent deficiency)
      • Senior Multivitamins: 500–1,000 mcg (absorption drops with age—keeps energy up and nerves healthy)
      • B-Complex Blends: Paired with B6 and folic acid (works together to make red blood cells and boost energy—fights fatigue)
    • Fortified Foods & Beverages
      • Plant Milks: Added to oat, almond, or soy milk (1–2 mcg per serving—makes vegan drinks as nutritious as dairy milk)
      • Breakfast Cereals: Sprinkled on cold cereals (easy morning dose—great for kids and busy adults)
      • Energy Drinks: Small doses (100–200 mcg) in no-sugar drinks (boosts energy without crashing—better than sugar)
    • Medical Uses
      • B12 Deficiency Shots: Methylcobalamin injections (for people who can’t absorb oral B12—e.g., gut surgery patients)
      • Nerve Pain Support: High-dose methylcobalamin (eases tingling in hands/feet from B12 deficiency)
    • Pet Wellness
      • Senior Pet Supplements: Tiny doses (50–100 mcg) in dog/cat vitamins (supports old pets’ energy and nerve function)
      • Vegan Pet Food: Added to plant-based dog food (prevents B12 deficiency in vegan pets)

Key Benefits (Why Vitamin B12 Is Non-Negotiable!)

  • Energy Boost: Converts food into energy—low levels cause constant tiredness, brain fog, and weakness (fixes that “I can’t get out of bed” feeling)
  • Nerve Health: Keeps nerves and the spinal cord healthy—prevents tingling, numbness, and even memory loss from deficiency
  • Red Blood Cell Production: Works with folic acid to make red blood cells—prevents B12-deficiency anemia (which makes you pale and breathless)
  • Brain Function: Supports memory and focus—low levels link to brain shrinkage in seniors (keeps your mind sharp as you age)
  • Vegan Lifesaver: The only B-vitamin not found in plants—vegan/vegetarian diets need supplements or fortified foods to avoid deficiency

Quick Tip

For vegans: Take B12 daily—even if you eat fortified foods, it’s easy to miss the dose. For seniors: Choose sublingual tablets (dissolve under the tongue)—they absorb better than regular pills. And if you feel constantly tired for no reason? Ask your doctor to check your B12 levels—it’s a common fix!
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The Ultimate Guide to Premium Vitamin B12: A Sourcing Guide for B2B Manufacturers

For over 28 years, Shaanxi Zhonghong Investment Technology Co., Ltd. has been a trusted name in the sourcing of high-purity bio-active compounds. As a leading Vitamin B12 manufacturer and exporter, we specialize in providing bulk ingredients that meet the rigorous standards of the global pharmaceutical, nutraceutical, and cosmetic industries. If you’re a product developer or procurement specialist looking for a reliable Vitamin B12 supplier, you’ve come to the right place. This comprehensive guide delves into everything you need to know about this essential ingredient.

1. What is Vitamin B12?

Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays a vital role in red blood cell formation, neurological function, and DNA synthesis. Unlike most vitamins, B12 is not produced by plants; it is synthesized by microorganisms. This makes sourcing a high-quality, consistent supply critical for your product formulations. For B2B clients, understanding the different forms—like cyanocobalamin and methylcobalamin—is the first step in selecting the right ingredient for your dietary supplements, functional foods, or cosmetics.

2. Source, Chemical Properties, and Specifications

Knowing the technical specifications is key to making an informed bulk purchase.

  • Product Source: Produced via microbial fermentation, ensuring a consistent, vegan-friendly, and high-purity product suitable for all applications.

  • Chemical Properties:

    • CAS Number: 68-19-9

    • Molecular Formula: C₆₃H₈₈CoN₁₄O₁₄P

    • Molecular Weight: 1355.37 g/mol

    • EINECS: 200-680-0

3. What Makes the Best Vitamin B12? A Manufacturer’s Breakdown

Choosing the right Vitamin B12 factory partner goes beyond price. Here’s what to look for:

  • Ingredient & Efficacy: The best B12 offers >98% purity, verified by HPLC. It must comply with global pharmacopoeia standards (USP, EP) for identity, potency, and safety.

  • Origin & Production: Our facility in China, operating under strict GMP, ensures full traceability from raw material to finished product.

  • Application & Usage: Easily incorporated into tablets, capsules, energy drinks, fortified cereals, and even anti-aging serums.

  • Target Audience: Ideal for dietary supplement raw material manufacturers creating products for vegans, the elderly, athletes, and those with specific health conditions.

  • Recommended Daily Intake & Dosage: Typical adult dosage is 2.4 µg/day. For supplementation, common doses range from 500 µg to 1000 µg. We help you determine the optimal dosage for your specific product matrix.

  • Side Effects & Precautions: Vitamin B12 is generally considered safe with a low risk of toxicity. However, proper dosing in formulations is essential.

4. Why Choose Shaanxi Zhonghong as Your Vitamin B12 Supplier?

Shaanxi Zhonghong Investment Technology Co., Ltd. is more than just a GMP certified plant extract company. We are your innovation partner.

  • Scientific Barrier: We maintain joint labs with 5 top-tier universities, holding over 20 patents. Our exclusive compound library allows for customized herbal extract solutions.

  • Leading Equipment: Our investment in High-Performance Liquid Chromatography (HPLC) and Superconducting Nuclear Magnetic Resonance (NMR) ensures our purity standards exceed industry averages by 20%.

  • Global B2B Network: We reliably supply OEM API to partners in over 80 countries across Asia, Europe, and the Americas.

We invite you to experience the Zhonghong difference. Contact us for a free sample of our premium Vitamin B12 and test it against your current supply.

5. Certificate of Analysis (COA) & Quality Control

Transparency is non-negotiable. Below is a summary of our stringent COA for Vitamin B12.

Category Item Name Index Test Method
Pesticide Residues Hexachlorocyclohexane ≤0.3mg/kg GB/T 5009.19
Dichlorodiphenyltrichloroethane ≤0.3mg/kg GB/T 5009.19
Heavy Metals Lead (Pb) ≤3.0 mg/kg ICP-MS
Arsenic (As) ≤2.0 mg/kg ICP-MS
Cadmium (Cd) ≤1.0 mg/kg ICP-MS
Mercury (Hg) ≤0.1 mg/kg ICP-MS
Microbiological Total Plate Count ≤1000 cfu/g USP <61>
Yeast & Mold ≤100 cfu/g USP <61>
E. Coli Negative USP <62>
Salmonella Negative USP <62>

Quality Control Promise:
Our quality control begins long before production. We employ a “Quality by Design” approach, starting with rigorous auditing of our raw material suppliers. Our state-of-the-art in-house laboratory, equipped with instruments like HPLC and GC-MS, allows us to perform real-time analysis at every stage of the manufacturing process—from fermentation and extraction to purification and drying. This closed-loop system ensures that every batch of our Vitamin B12 meets precise specifications for identity, purity, strength, and composition. We adhere to cGMP and are prepared to meet the specific regulatory requirements of your market, whether that’s FDA, EFSA, or others. Our detailed documentation and batch traceability provide you with the confidence and paperwork needed for your own regulatory submissions. When you partner with us, you are guaranteed a food-grade botanical extract supplier that prioritizes safety and consistency above all else.

6. Production Workflow & Application Scenarios

  • Production Workflow: Strain Selection → Microbial Fermentation → Extraction & Purification → Crystallization → Drying → Milling → Quality Control → Packaging.

  • Application & Usage:

    • Dietary Supplements: Capsules, tablets, softgels.

    • Food & Beverage: Fortified drinks, energy bars, infant formula.

    • Pharmaceuticals: Prescription B12 injections and high-dose formulations.

    • Cosmetics: Used in anti-aging skincare for its revitalizing properties.

7. Packaging & Logistics

We offer flexible packaging to suit your needs: from 1kg aluminum foil bags with double polyethylene liners to 25kg fiber drums. All packages are sealed for moisture protection and labeled clearly for easy identification. We have established partnerships with major global logistics providers to ensure your order arrives on time and in perfect condition, whether you need a small sample or a full container load.

8. Health Benefits, Industry Applications & The Future

Vitamin B12 is essential for energy metabolism, cognitive health, and nervous system maintenance. As a cosmetic raw material supplier, we see growing interest in its topical applications for skin rejuvenation. The industry is moving towards more bioavailable forms and innovative delivery systems. At Zhonghong, our R&D team is at the forefront, exploring novel fermentation techniques to enhance yield and purity. The challenge remains cost-effective production at scale, which is where our 28 years of experience give our partners a competitive edge.

Ready to elevate your product line? Partner with a supplier that guarantees quality, consistency, and innovation.

9. Frequently Asked Questions (FAQ)

  • Q: Can you provide customized Vitamin B12 powder?

    • A: Absolutely. As an OEM API supplier in China, we can customize particle size, carrier agents, and create private-label blends to your exact specifications.

  • Q: What is your MOQ (Minimum Order Quantity)?

    • A: For standard products, our MOQ can be as low as 1kg. For customized herbal extract projects, we can discuss volume requirements.

  • Q: Do you offer documentation support?

    • A: Yes. We provide comprehensive support including COA, MSDS, and other regulatory documentation required for your market.

  • Q: Where can I buy or get a free sample?

    • A: You can request a free sample herbal extract directly from us. Reach out to our sales team to discuss your needs.

10. Conclusion & Call to Action

In the competitive world of ingredient sourcing, the quality of your raw materials defines the success of your final product. Choosing a seasoned, technologically advanced manufacturer like Shaanxi Zhonghong mitigates risk and ensures excellence.

Take the next step today. Contact us for a quote, technical data sheet, or to request your complimentary sample.

11. References

  • Office of Dietary Supplements – National Institutes of Health (NIH)

  • United States Pharmacopeia (USP)

  • European Pharmacopoeia (Ph. Eur.)

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