Versicolor Psk
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Versicolor PSK

Versicolor PSK supplier bulk factory Wholesale Extract factory

  1. Nome em inglês: Polysaccharide – OK (PSK), também conhecido como Krestin
  1. Especificação
    • Comum Pó: PSK ≥ 95% (HPLC), molecular weight round 100 kDa
    • Water – soluble Tipo: Extremamente solúvel em água, formando um líquido transparente opções; PSK conteúdo material ≥ 90% in water – soluble formulations, with correto solubility – enhancing corretores
  1. Aparência
    • Pó: Leve – brown to off – white tremendo powder, odorless or with a faint, earthy scent
    • Water – soluble Tipo: Clear para por muito pouco yellowish liquid
  1. CAS NO.：65963 – 10 – 0
  1. Tempo de espera: 5 – 10 dias úteis
  1. Pacote
    • 1 kg/bag (aluminum foil bag), 5 kg/drum (sterilized stainless – metal drum with vacuum seal for pharmaceutical – grade mercadoria); 25 kg/drum (double – layer PE bag inside cardboard drum for industrial – grade mercadoria)
  1. Mercado Principal: Asia (Japan, China, South Korea), North America, Europe
  1. Cenários de Aplicação

Propriedades principais

  • Molecular Construção: A protein – certo polysaccharide, composed of a β – glucan coluna with β – 1,4 importante chains and β – 1,3 and β – 1,6 aspect chains. The protein papel é hooked up to the β – 1,6 aspect chains.
  • Solubilidade: Soluble in water, which is useful para numerosos propósitos, particularmente in pharmaceutical and nutraceutical formulations.
  • Chave Opções
    • Imunomodulador: Potently modulates the immune system by activating macrophages, T – lymphocytes, and puro killer cells. It helps the immune system to raised acknowledge e meta irregular cells, semelhante a a maioria dos cânceres cells, enquanto adicionalmente parando over – activation that might resultar em autoimmune – like reactions.
    • Adjuvante antitumoral: Has comprovado importante adjuvant anti – tumor exercício in vitro and in vivo em oposição a numerosos cancers, junto com colorectal, gastric, breast, liver, pancreatic, and lung a maioria dos cânceres. Realmente funciona junto with chemotherapy and radiotherapy, enhancing their efficacy and decrescente aspect – resultados.
    • Antioxidante: Elimina os radicais livres, defendendo células de oxidação ferida, que é relacionado a envelhecendo, irritação, e numerosos doenças.
    • Baixa toxicidade: Geralmente bem – tolerated by the human físico, with minimal aspect – resultados, fazendo isso apropriado para longo – time period use in bem estar – vendendo and therapeutic propósitos.

Cenários de Aplicação

1. Medicamentos prescritos

  • Most cancers Remédio:
    • Adjuvante Remédio: Extensivamente utilizado em Japan as an adjuvant immunotherapy for um número de cancers. Together com quimioterapia medicamento (semelhante a 5 – fluorouracil for colorectal a maioria dos cânceres), it might probably melhorar remédio outcomes. Médico pesquisar ter comprovado que it might probably melhorar the survival preço de a maioria dos cânceres sofredores, melhorar deles alta qualidade of life, and reduzir a escala chemotherapy – induced immunosuppression.
    • Imune Ajuda: Ajuda a maioria dos cânceres sofredores preservar um saudável sistema imunológico por todo remédio, decrescente a chance of infections and diferente problemas. Por exemplo, in non – small cell lung carcinoma sofredores processo atual radiotherapy, PSK supplementation can melhorar imune executar e reduzir a escala the severity of radiation – induced aspect – resultados.
  • Fígado Segurança:
    • Pesquisar have demonstrated that PSK can defender the liver from ferida, semelhante a que provocado por alcohol. Poderia reduzir a escala the degrees of liver – executar markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in alcohol – induced liver ferir modas, suggesting its potential use in liver – defendendo medicação.

2. Nutracêuticos

  • Immune – boosting Suplementos alimentares:
    • Lá fora in capsule, pílula, or powder tipo dentro do nutraceutical market. Customers can take it cada dia to strengthen their immune métodos, particularmente por todo seasons when a chance of infections is excessivo. It is usually apropriado para indivíduos com imunidade enfraquecida métodos por causa de contínuo doenças ou envelhecendo.
  • Prático Refeições:
    • Integrado em útil refeições como vitalidade bars, yogurt, and bebidas. As an illustration, alguns bem estar – targeted yogurt mercadoria compreender PSK para fornecer compradores com an extra immune – boosting lucro junto com o dietético valor do refeições.

3. Cosméticos

  • Anti- envelhecendo Mercadoria:
    • Added to serums, loções, and masks for its antioxidant and immunomodulatory properties. Poderia ajudar reduzir a escala a aparência de tremendo vestígios and wrinkles by defendendo poros e pele cells from oxidative stress and vendendo um saudável poros e pele immune response.
  • Poros e pele – Soothing Formulations:
    • Em mercadoria designed for delicado ou irritado poros e pele, PSK’s anti – inflammatory properties pode ajudar calm the poros e pele, reduzir a escala redness, and promote poros e pele restaurar.

Detecção Estratégias

  • Excessivo – Eficiência Cromatografia Líquida (CLAE):
    • Column: An acceptable carbohydrate – avaliação column (e.g., TSKgel GMPWXL, 300 × 7.8 mm). Célula Seção: A combination of solvents like 0.7% sodium sulfate resolução. Circular Cobrar: 0.6 – 1.0 mL/min. Detection é geralmente realizado utilizando a refractive index detector or an evaporative leve – scattering detector to precisamente quantify PSK conteúdo material.
  • Gel Permeation Chromatography (GPC):
    • Usado para descobrir the molecular weight distribution of PSK. It separates the polysaccharide molecules baseado principalmente on their dimensão, oferta detalhes sobre the typical molecular weight and the polydispersity index.
  • Immunological Assays:
    • ELISA (Enzyme – Linked Immunosorbent Assay) – baseado principalmente estratégias pode ser developed to particularmente detect PSK, profiting from its protein – certo nature. Antibodies em oposição a PSK pode ser utilizado para seize and detect the polysaccharide in samples, which is helpful para alta qualidade gerenciamento in product manufacturing.

Fornecer & Benefícios

  • Natural Fornecer: Extracted from the mycelium of Trametes versicolor, um padrão basidiomycete mushroom também conhecido como turkey tail. It has um prolongado passado histórico of use in convencional Asian drogas, particularmente in China and Japan, courting de novo to the Ming Dynasty (1368 – 1644).
  • Validação Científica: In depth científico análise, junto com in – vitro and in – vivo pesquisar, in addition to científico trials, has validated its immunomodulatory and antitumor properties. This scientific prova ofertas um poderoso base for its use in na moda drogas e bem estar mercadoria.
  • Multi – útil Benefícios: Isso é skill to modulate the immune system, act as an antioxidant, and ajudar numerosos elementos de bem estar makes it um flexível ingredient with propósitos por todo completamente diferente indústrias, de medicamentos prescritos to cosmetics.

Conformidade regulatória

  • Japan: Permitted como um medicamento adjuvante para a maioria dos cânceres remédio, with strict Good Manufacturing Follow (GMP) necessidades para fabricação. It has been used dentro do Japanese healthcare system for many years, and its segurança and efficacy are bem – established dentro do context of a maioria dos cânceres adjuvante remédio.
  • China: Reconhecido como um precioso medicinal ingredient. Mercadoria containing PSK querer para satisfazer o regras do Em todo o país Médico Mercadoria Administration (NMPA) for cada pharmaceutical and nutraceutical propósitos.
  • US and Europe: In the USA, PSK is regulated as a dietary complemento abaixo the Dietary Complemento Bem estar e Schooling Act (DSHEA). In Europe, it falls abaixo o regras for novel refeições e refeições suplementos alimentares, com necessidades para segurança avaliação and labeling.
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Versicolor PSK (Polysaccharide-Krestin): Premium Immune-Assist Ingredient for Nutraceutical & Pharmaceutical Purposes – Manufacturer Information

1. What is Versicolor PSK?
For product builders within the immune well being area, Versicolor PSK (Polysaccharide-Krestin) stands as a premier, clinically researched bioactive compound. It’s a proprietary protein-bound polysaccharide (β-glucan) extract derived from the deep-layer cultivated mycelium of the Trametes versicolor ou Coriolus versicolor mushroom. In contrast to easy mushroom powders, PSK is a extremely refined, standardized extract with a well-documented historical past of use in supportive care, making it a high-value ingredient for classy nutraceutical and pharmaceutical formulations.

2. Suprimento, Química e Especificações

  • Fornecer: Derived from the classy mycelium of Trametes versicolor (Turkey Tail mushroom).

  • Bioativo chave: A protein-bound polysaccharide complicated, primarily β-glucans with a particular construction and molecular weight profile.

  • Perfil químico: As a fancy organic polymer, it doesn’t have a single CAS, MF, or MW. Its identification is outlined by its distinctive polysaccharide-protein composition and organic exercise.

  • Aparência: Wonderful brownish powder with a attribute gentle, fragrant odor.

  • Solubilidade: Partially soluble in water, forming a colloidal answer.

3. The Formulator’s Alternative: Why Standardized PSK is Finest
Para B2B shoppers within the complement and wellness industries, not all mushroom extracts are created equal. Right here’s why standardized PSK is the benchmark:

  • Diferencial chave: Standardization to particular polysaccharide content material (e.g., ≥ 30% or greater) ensures constant organic exercise and efficacy, which is important for reproducible product outcomes.

  • Confirmed Well being Benefits (Compliant Claims for Producers):

    • Modulação do sistema imunológico: Helps and helps regulate wholesome immune operate.

    • Propriedades antioxidantes: Helps shield cells from oxidative stress.

    • General Wellness Assist: Promotes common well being and vitality.

    • (Notice: Particular illness claims are topic to drug approval in most areas and can’t be made for dietary dietary supplements).

  • Typical Use Degree: Medical research usually use doses from 1 to three grams per day of the purified extract. Formulation dosage must be decided primarily based on the specified efficiency of the ultimate product.

  • Origem e alta qualidade: Produced beneath strict, managed fermentation situations to make sure purity, consistency, and absence of environmental contaminants.

  • Aplicativo: Preferrred for capsules, tablets, and powdered drink formulations the place a potent, water-soluble extract is required.

  • Goal Industries & Formulations:

    • Nutracêuticos: Excessive-potency immune help dietary supplements, wellness formulation.

    • Refeições e bebidas com propósito: Fortified well being drinks and powders.

    • Cosmecêuticos: Skincare merchandise for its antioxidant advantages.

  • Security & Regulatory: Has an extended historical past of secure use. Usually well-tolerated. Minor uncomfortable side effects might embody gentle digestive upset.

4. Zhonghong Biotech: Your World Manufacturer & Export Accomplice
Sourcing a dependable, high-potency PSK supplier is a important choice. Tecnologia de Investimento Shaanxi Zhonghong Co., Ltd. is a licensed Fabricante e Exportador with over 28 years of experience in superior extraction and fermentation expertise for the worldwide B2B market.

  • Competência principal: We specialize within the cultivation, extraction, and purification of premium fungal and botanical bioactives. Our portfolio consists of:

    • Standardized Mushroom Extracts (PSK, PSP, Reishi, Cordyceps)

    • Nutraceutical Elements

    • Lively Pharmaceutical Elements (APIs) & Intermediates

  • Why Worldwide Purchasers Select Us:

    • Excelência científica: 20+ patents and collaborations with 5 main universities guarantee we’re on the forefront of mycological extraction expertise.

    • Gestão de alta qualidade incomparável: Nosso financiamento em HPLC, HPTLC, and NMR spectroscopy ensures a purity and efficiency customary that constantly exceeds business specs.

    • World B2B Export Community: We’re a trusted Exportador para dietary complement, pharmaceutical, practical meals, and beauty industries in over 80 nations, providing tailor-made opções de ingredientes personalizados.

5. Technical Perception: Mechanism of Motion
PSK’s main immunomodulatory results are attributed to its capability to bind to particular receptors on immune cells (e.g., dendritic cells, macrophages), enhancing their communication and response. This results in a extra coordinated and environment friendly immune exercise, which is the idea for its widespread use in supportive well being purposes.

6. Iron-Clad High quality Dedication: The COA
Our High quality Management is designed for regulatory compliance and buyer belief. Each batch is rigorously examined to satisfy stringent specs.

Certificates of Evaluation (COA) Abstract – Versicolor PSK

Aula Parâmetro Especificação Técnica de verificação
Ensaio Polissacarídeos ≥ 30,0% UV-Vis / Phenol-Sulfuric Acid
β-Glucans ≥ 20.0% Enzymatic Technique
Metais Pesados Chumbo (Pb) ≤ 0,5 mg/kg ICP-MS
Arsênio (As) ≤ 0,5 mg/kg ICP-MS
Cádmio (Cd) ≤ 0,2 mg/kg ICP-MS
Mercúrio (Hg) ≤ 0,1 mg/kg ICP-MS
Microbiologia Prato Inteiro Confie ≤ 5,000 CFU/g USP <61>
Levedura e mofo ≤ 100 UFC/g USP <61>
E. coli Adverse in 1g USP <62>
Salmonela spp. Adverse in 10g USP <62>
Diferente Perda na secagem ≤ 8,0% USP <731>
Solventes Residuais Atende ICH Q3C GC-FID

(Um COA completo e específico do lote é fornecido com cada carga.)

7. Curso Superior de Fabricação de
Our cGMP-compliant course of ensures a superior, constant extract:

  1. Pressure Choice & Cultivation: Use of a proprietary, high-yield Trametes versicolor pressure cultivated in managed bioreactors.

  2. Fermentação: Optimized submerged fermentation to maximise biomass and bioactive manufacturing.

  3. Extração: Sizzling water extraction beneath managed time and temperature to isolate the polysaccharide-protein complicated.

  4. Filtragem e Foco: Removing of insoluble matter and focus of the energetic extract.

  5. Purificação: Additional refinement steps to realize the goal polysaccharide focus.

  6. Secagem por pulverização: Conversion right into a secure, fantastic powder.

  7. Standardization & QC: Exact mixing to ensure constant efficiency, adopted by full analytical testing.

8. Aplicação em Formulações B2B
This ingredient is a cornerstone for superior immune and wellness merchandise:

  • Suplementos alimentares: Capsules and tablets for immune help.

  • Refeições e bebidas com propósito: Fortified powders, well being drinks, and photographs.

  • Vitamina Médica: Merchandise designed for supportive care.

  • Cosmecêuticos: Premium skincare serums and lotions.

9. B2B Packaging & World Export Logistics

  • Embalagem: 1 kg / 5 kg double-sealed luggage inside 25 kg fiber drums. Customized embalagens a granel accessible.

  • Armazenar: Retailer in a cool, dry, and well-ventilated place. Preserve container tightly sealed.

  • Prazo de validade: 24 months when saved beneath really helpful situations.

  • Logística: As an skilled Exportador, we deal with all worldwide transport, documentation (COA, MSDS, Certificates of Origin), and guarantee easy customs clearance.

10. Accomplice with Us for Your Bulk Ingredient Wants
Zhonghong Biotech is your strategic companion for high-purity, potent substances. We offer:

  • Aggressive Bulk Pricing: Obtenha um direto manufacturing unit value para pedidos de alto volume.

  • Personalização e OEM: Nós fornecemos personalizado extracts with various polysaccharide concentrations and blends.

  • Assistência regulatória: Documentation to help your product registrations.

Contact Us for a Quote or to Request a Pattern!

  • Líquido: www.aiherba.com

  • E-mail: vendas@aiherba.com; liaodaohai@gmail.com

  • Frases-chave: Versicolor PSK supplier, bulk PSK, Polysaccharide-Krestin producer, purchase Trametes versicolor extract, wholesale mushroom extract, immune help ingredient supplier, extrato natural personalizado, pharmaceutical uncooked materials supplier.

11. FAQ for B2B Purchasers

  • P: Qual é o seu valor mínimo de pedido (MOQ)?
    A: Contact us for particular MOQ particulars. We provide versatile phrases for volume e atacado companheiros.

  • Q: Are you able to present PSK with totally different polysaccharide standardizations?
    A: Sure. We will present technical steering and opções personalizadas (e.g., 30%, 40%, 50% polysaccharides) primarily based in your formulation targets.

  • Q: Do you present full regulatory documentation for export?
    A: Completely. We offer a complete Certificates of Evaluation (COA), MSDS, and different needed export paperwork.

  • Q: What is the lead time for big orders?
    A: Lead instances differ primarily based on order measurement. We preserve strategic inventory and supply clear manufacturing timelines.

  • Q: How can we begin the qualification course of?
    A: Envie-nos um e-mail para vendas@aiherba.com para solicitar um padrão livre and focus on your technical specs.

12. Conclusão
For manufacturers formulating within the aggressive immune well being market, standardized Versicolor PSK gives a confirmed, high-efficacy choice. Partnering with a technically superior, dependable Fabricante e Exportador is important for guaranteeing ingredient high quality, provide chain safety, and last product integrity. Zhonghong Biotech, with its scientific experience, rigorous QC, and international export functionality, is the optimum companion for indústrias nutracêuticas e farmacêuticas. Contact us immediately to debate your venture wants and request a pattern.

Referências:

  • Standish, L.J., et al. (2008). Trametes versicolor mushroom immune remedy in breast most cancers. Journal of the Society for Integrative Oncology.

  • Kidd, P.M. (2000). Using mushroom glucans and proteoglycans in most cancers remedy. Various Drugs Overview.

  • Tsukagoshi, S., et al. (1984). Krestin (PSK). Most cancers Remedy Opinions.

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