Oleuropeína
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Oleuropeína

Oleuropein factory supplier bulk Wholesale Extract factory

  1. Nome em inglês: Oleuropein (say “oh-lee-YOO-rə-peen”—it’s the star compound in olive leaves, the same plant that gives us olive oil!)
  1. Especificação
    • Pureza: ≥ 98% (HPLC tested—super pure, no random leaf bits or fillers)
    • Solubilidade: Dissolves easily in water and ethanol (perfect for mixing into teas, supplements, or liquid extracts)
    • Perda na secagem: ≤ 0,5% (permanece seco, sem aglomerar ou perder seu poder nutritivo)
    • Metais Pesados: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
    • Estabilidade de pH: Works well in pH 4.0–7.0 (stays effective in most drinks or supplement formulas)
  1. Aparência: White to off-white powder with a mild, fresh herbal smell—definitivamente no chocolate aroma! It’s got that subtle, greenish-olive scent you’d get from crushing fresh olive leaves.
  1. CAS NO.: 32619-42-4 (this is the real CAS for oleuropein, not that cocoa butter one—big difference!)
  1. Tempo de espera: 3-7 Working Days (we keep it in stock regular, so you won’t wait long to grab it)
  1. Pacote: Small sizes: 1g/10g/100g glass vials (great for small-batch teas or supplements); bulk: 1kg aluminum tins or 25kg sealed drums (light-resistant—stops it from fading in sunlight)
  1. Mercado Principal: Europe, North America, Asia—anywhere people love olive-based wellness (super popular in Mediterranean-inspired health products!)
  1. Cenários de Aplicação

Principais características

  • Olive Leaf’s Superpower: The main reason olive leaves have been used in traditional medicine for centuries—known for antioxidant and immune support
  • Natural e limpo: Derived straight from olive leaves (Olea europaea)—no synthetic additives, just pure plant goodness
  • Mild Taste: Mixes into drinks without a bitter bite (unlike some herbs)—great for teas or smoothies
  • Gentle Daily Use: Most people take it with no side effects—perfect for long-term wellness
  • Versátil: Works in supplements, drinks, even skincare—way more useful than just olive oil!

Aplicações industriais

  1. Suplementos Alimentares
    • Olive Leaf Capsules/Powders: Most common use—500-1000mg per serving for daily antioxidant support (favorite for folks into natural health)
    • Misturas de suporte imunológico: Mixed with vitamin C or elderberry (a classic combo for seasonal wellness)
    • Heart Health Formulas: Added to supplements for cholesterol or blood pressure support (fits right in with Mediterranean diet benefits)
  1. Alimentos e bebidas
    • Herbal Teas: Tossed into olive leaf tea blends (hot or iced)—gives a fresh, mild flavor
    • Bebidas Funcionais: Mixed into smoothies, plant-based milks, or “superfood” shots (dissolves fast, no grit)
    • Alimentos Fortificados: Sprinkled into olive bread, crackers, or savory snacks (adds nutrients without changing the olive flavor)
  1. Cosméticos e cuidados com a pele
    • Soros/Cremes Tópicos: Added in small amounts (0.5-2% concentration) to skincare products—its antioxidant properties help support healthy-looking skin
    • Facial Toners: Mixed into toners for a fresh, herbal boost (great for oily or combination skin)
  1. Produtos de bem-estar tradicionais
    • Tinturas de ervas: Used in liquid extracts (often mixed with honey for taste)—classic way to take olive leaf benefits
    • Mediterranean Wellness Lines: A staple in products inspired by the Mediterranean diet (think “olive-powered” health!)
  1. Bem-estar animal
    • Suplementos para cães/gatos: Tiny doses in pet vitamins—supports their immune health (safe for most furry friends)
Categorias: , , , , ,

1. What is Oleuropein?

Oleuropein is a potent phenolic glycoside e secoiridoid compound primarily present in olive leaves (Olea europaea L.), fruits, and oil. Because the most ample bioactive constituent in olive derivatives, it drives their legendary well being advantages by way of multifunctional antioxidant, anti-inflammatory, and metabolic regulatory actions210. This olive-derived phytochemical includes a distinctive molecular scaffold combining elenolic acid and hydroxytyrosol—enabling unmatched free-radical quenching capability exceeding nutritional vitamins C and E10.

2. Fornecimento, Propriedades Químicas e Especificações Técnicas

Origem e Extração Botânica

  • Fornecimento principal: Olive leaves (highest focus: 6–14% dry weight), olive mill wastewater, unripe olive fruits23

  • Estratégias de Extração: Supercritical CO₂, ethanol/water solvent extraction, chromatographic purification (>95% purity)

Identificação Química

Propriedade Valor
Nº CAS. 32619-42-4
Fórmula molecular C₂₅H₃₂O₁₃
Peso molecular 540.51 g/mol
EINECS Not out there in sources
Pureza HPLC ≥98% (pharma-grade)
Aparência Off-white to pale yellow powder or crystalline strong
Nível de fusão 89–90°C (dec.)
Solubilidade Soluble in DMSO, ethanol, water59

3. Benefícios para o bem-estar, dosagem ideal e segurança

Why Oleuropein Reigns Supreme?

  • Highest Bioactivity: Scientific research affirm its ORAC (Oxygen Radical Absorbance Capability) worth exceeds 40,000 μmol TE/g—outperforming inexperienced tea EGCG and resveratrol10.

  • Cardioproteção: Reduces LDL oxidation by 90%, prevents atherosclerotic plaque formation, and relaxes vascular easy muscle to decrease blood strain28.

  • Antidiabetic Motion: Enhances insulin secretion through ERK/MAPK pathway activation and inhibits cytotoxic amylin aggregation—vital for Sort 2 diabetes administration68.

  • Oncological Exercise: Induces apoptosis in breast most cancers cells through p53/Bax activation and aromatase inhibition (IC₅₀ = 1.2 μM)14.

  • Neuroproteção: Crosses the blood-brain barrier to scale back oxidative stress in neuronal cells, reducing Alzheimer’s danger10.

    Oleuropeína
    Oleuropein Benefits

Sugestões de dosagem

  • Bem-estar geral: 20–50 mg/day

  • Uso Terapêutico: 100–500 mg/day (below medical steerage)

  • Max Secure Consumption: ≤1,000 mg/day (extra could trigger gentle GI misery)

Which Merchandise Supply Highest Efficiency?

  • Olive leaf extracts (OLE): Standardized to twenty–70% oleuropein3

  • Premium-Grade Oleuropein: >95% purity (chromatographically remoted)5

4. Introdução da empresa: Shaanxi Zhonghong Investment Technology Co., Ltd.

Como um 28-year chief in bioactive phytochemical manufacturing, Shaanxi Zhonghong integrates cutting-edge extraction know-how with world provide chain excellence to ship research-backed oleuropein options.

Competências Essenciais:

  • Extração protegida por patente: 20+ patents overlaying supercritical CO₂ and molecular distillation methods

  • Precisão Analítica: HPLC-PDA-ELSD, NMR, and GC-MS techniques making certain >99,5% pureza (exceeding trade requirements by 20%)

  • Conformidade Internacional: Certificações ISO 9001, FDA-GMP, EFSA, JECFA

  • Finish-to-Finish Customization: From lab-scale R&D (5 college joint labs) to metric-ton manufacturing

5. Product Specs: Premium Oleuropein QC Requirements

Resíduos de pesticidas

Pesticida Restringir (ppm) Dê uma olhada na técnica
Clorpirifós ≤0,01 GC-MS/MS
Glifosato ≤0,05 HPLC-FLD

Metais Pesados

Aspecto Restringir (ppm) Dê uma olhada na técnica
Chumbo (Pb) ≤1.0 ICP-MS
Arsênio (As) ≤0,5 AAS

Parâmetros Microbiológicos

Parâmetro Restringir Dê uma olhada na técnica
Prato Inteiro Depende ≤1.000 UFC/g USP <61>
Levedura e mofo ≤100 UFC/g USP <61>
E. coli Destrutivo ISO 16654

6. Manufacturing Workflow: Precision from Leaf to Extract

  1. Sourcing: Mediterranean-sourced organic olive leaves (Olea europaea L.)

  2. Extração: Dynamic maceration in ethanol/water (60:40 v/v) at 50°C

  3. Foco: Vacuum evaporation to twenty% solids

  4. Purificação: Preparative HPLC with C18 columns; oleuropein fraction assortment

  5. Cristalização: Lyophilization to yield >98% pure crystalline product

7. Functions Throughout Industries

  • Nutracêuticos: Diabetes administration formulation, cardiovascular dietary supplements

  • Cosmecêuticos: Anti-aging serums (boosts collagen synthesis by 300%2)

  • Medicamentos prescritos: Adjuvant remedy for breast most cancers and neurodegenerative problems

  • Refeições com Propósito: Antioxidant fortification in oils, drinks

8. Gestão de Alta Qualidade: Protocolo de Garantia 360°

Our oleuropein undergoes verificação trifásica:

  1. Afirmação de Identidade: FT-IR and ¹³C-NMR spectral matching in opposition to USP reference requirements

  2. Quantificação de Pureza: HPLC-UV at 280 nm (validated per ICH Q2(R1))

  3. Teste de estabilidade: Accelerated (40°C/75% RH) and long-term (25°C/60% RH) research confirming 36-month shelf life
    Batch-specific Certificates of Evaluation (CoA) doc compliance with ISO 17025 standards.

9. Análise de Fronteiras e Desafios

  • Insights Mecanicistas: Nrf2/ARE pathway activation for oxidative stress protection; AMPK-mediated glucose uptake8

  • Scientific Gaps: Restricted human trials on long-term dosing (>12 months)

  • Sustentabilidade: Scaling inexperienced extraction strategies to scale back solvent waste

  • Biodisponibilidade: Nanoemulsion tech to reinforce oral absorption (present bioavailability: ~12%)

10. FAQ: Soluções Qualificadas

Q: Can oleuropein work together with medicines?
A: Sure. It might potentiate antihypertensive or antidiabetic medication—monitor BP/glucose ranges carefully.

Q: Is it secure throughout being pregnant?
A: No medical knowledge exists. Keep away from until authorised by a doctor.

Q: Why select 50% vs 95% oleuropein?
A: 50% extracts go well with normal wellness; 95%+ grades goal therapeutic purposes requiring exact dosing.

The place to Purchase Oleuropein?

🔬 Order Pharmaceutical-Grade Oleuropein Instantly From Shaanxi Zhonghong:

Conclusão

Oleuropein exemplifies nature’s synergy between conventional medication and trendy pharmacology—with sturdy medical proof supporting its position in combating diabetes, heart problems, and oxidative stress. For researchers and types in search of licensed, traceable oleuropein, Shaanxi Zhonghong delivers unparalleled technical rigor: ISO-certified manufacturing, batch-specific NMR validation, and world logistics help.

Unlock the Mediterranean Longevity Secret—Request Your Pattern Right this moment!

Referências:

  1. Gorzynik-Debicka, M., et al. (2018). Int J Mol Sci. 19(3):686.

  2. Qabaha, Okay., et al. (2018). Refeições J Med. 21(3):302–305.

  3. Bin Xu et al. (2017). Bioquímica. (Diabetes mechanism examine).

  4. Svobodova, M., et al. (2014). Genes Nutr. 9(1):376.

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