Polissacarídeos de Ganoderma Lucidum
Ganoderma Lucidum Polysaccharide - Imagem 2
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Polissacarídeo de Ganoderma lucidum

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. Nome em inglês: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Especificação
    • Conteúdo de polissacarídeos: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Solubilidade: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Umidade: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Metais Pesados: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
    • Pureza: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Aparência: Light yellow to off-white powder with a mild, earthy mushroom smell—definitivamente no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. CAS NO.: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Tempo de espera: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Pacote: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Mercado Principal: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Cenários de Aplicação

Principais características

  • O “Superpoder” de Reishi: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Mix-In versátil: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Natural e limpo: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Armazenamento estável: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Aplicações industriais

  1. Suplementos Alimentares
    • Cápsulas/Pós de Reishi: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • Fórmulas de suporte imunológico: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Alimentos e Bebidas Funcionais
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Produtos de bem-estar tradicionais
    • TCM Formulations: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Nutrição Especializada
    • Bem-estar Sênior: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Produtos veganos/à base de plantas: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness
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Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. What Are Ganoderma Lucidum Polysaccharides?

Ganoderma lucidum polysaccharides (GLPs) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Reishi mushroom). Structurally, they comprise β-(1→3)-D-glucan backbones com β-(1→6)-D-glucosyl branches, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1,000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.

2. Fornecimento, Propriedades Químicas e Especificações Técnicas

Fontes e Extração Botânica

  • Fornecimento principal: Fruiting our bodies of Ganoderma lucidum ou G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Estratégias de Extração:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ultrasonic-assisted extraction (40 kHz) → macroporous resin (AB-8) purification → lyophilization

Chemical Identification

Propriedade Valor
Nº CAS. Not assigned (advanced combination)
Fórmula molecular (C₆H₁₀O₅)ₙ
Peso molecular 10–1,000 kDa
EINECS Not relevant
Aparência Mild brown hygroscopic powder
Solubilidade Water-soluble; insoluble in ethanol
Key Bioactivity β-(1→3)/(1→6) glycosidic bonds ≥85%

3. Benefícios para o bem-estar, dosagem ideal e segurança

Resultados Terapêuticos Validados

  • Imunomodulação:

    • ↑ Macrophage phagocytosis by 300% and ↑ NK cell cytotoxicity by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • Induz apoptosis in HepG2 cells (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Regulação Metabólica:

    • ↓ Fasting blood glucose by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoproteção:

    • Reduz ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Sugestões de dosagem

  • Bem-estar geral: 100–300 mg/day (20–30% GLPs)

  • Uso Terapêutico:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Limite de segurança: ≤3,000 mg/day (no noticed toxicity)9.

Precauções vitais

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Procedimento cirúrgico: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Interações medicamentosas: Might potentiate immunosuppressants (e.g., cyclosporine).

4. Introdução firme: Shaanxi Zhonghong Biotechnology Co., Ltd.

UM 28-year pioneer in bioactive polysaccharide manufacturing, Shaanxi Zhonghong integrates proprietary extraction tech with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Capacidades Essenciais:

  • Extração protegida por patente: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Rigor Analítico: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain >99,5% pureza (excedendo monografias USP/EP).

  • Conformidade Internacional: Certificações ISO 9001, FDA-GMP, EFSA, JECFA.

  • Domínio da Cadeia de Fornecimento: Logística de cadeia fria em mais de 80 países.

5. Product Specs: Pharmaceutical-Grade GLP QC

Requisitos para testes de contaminantes

Aula Parâmetro Restringir Técnica de verificação
Pesticidas Clorpirifós ≤0,01 ppm GC-MS/MS (UE 396/2005)
Glifosato ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Metais Pesados Chumbo (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsênio (As) ≤0,5 ppm AAS (EP 2.4.27)
Microbiologia Prato Inteiro Depende ≤1.000 UFC/g USP <61>
E. coli Ausente ISO 16654
Salmonela spp. Ausente FDA BAM Cap. 5

6. Fluxo de trabalho de fabricação superior

  1. Sourcing: Natural G. lucidum fruiting our bodies (OOP-certified).

  2. Extração: Dynamic maceration (95°C, pH 6.8, 3h) → ultrafiltration (100 kDa MWCO).

  3. Deproteinization: Sevag reagent (chloroform:butanol 4:1).

  4. Purificação: DEAE-Sepharose FF chromatography → lyophilization.

  5. Padronização: Phenol-sulfuric acid assay to 40% GLP content material.

7. Propósitos em todas as indústrias

  • Nutracêuticos: Immune-boosting capsules (GLP + β-glucan synergy).

  • Medicamentos prescritos: Chemotherapy adjuvants (reduces cisplatin nephrotoxicity).

  • Cosmecêuticos: Anti-aging serums (↑ collagen synthesis by 200%).

  • Refeições Úteis: Glycemic management drinks (GLP + berberine).

8. Gestão de Alta Qualidade: Protocolo de Garantia 360°

GLP batches bear verificação de quatro fases:

  1. Afirmação de Identificação: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,070 cm⁻¹ C-O-C).

  2. Quantificação de Pureza: HPSEC-ELSD (ICH Q2(R1)-validated; LOD: 0.05%).

  3. Teste de bioatividade:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • α-Glucosidase inhibition: IC₅₀ ≤ 2 mg/mL

  4. Estabilidade: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).

9. Análise de Fronteiras e Desafios

  • Insights Mecanicistas:

    • Intestine microbiota modulation (↑ Bifidobactéria ↑ SCFA manufacturing).

    • STING pathway activation for antitumor immunity.

  • Tradução Médica:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Technical Boundaries:

    • Biodisponibilidade oral: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Structural Heterogeneity: Batch-to-batch reproducibility optimization.

  • Sustentabilidade:

    • Mycelial fermentation to preserve wild Ganoderma populations.

10. FAQ: Soluções Qualificadas

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

P: Qual o melhor horário para consumo?
A: Morning on empty abdomen (enhances macrophage uptake).

The place to Purchase Pharmaceutical-Grade GLPs

🔬 Pedido direto de Shaanxi Zhonghong:

Conclusão

Ganoderma lucidum polysaccharides redefine precision immunonutrition—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!

Referências:

  1. Revista de Etnofarmacologia (2019). GLP mechanisms in most cancers apoptosis9.

  2. Polímeros de Carboidratos (2020). Structural characterization of immunomodulatory GLPs6.

  3. Química das Refeições (2021). Ultrasonic-microwave extraction optimization3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Frontiers in Immunology (2024). STING pathway activation by GLPs.

1 avaliação de Ganoderma lucidum polysaccharide

  1. Avatar De James Oli***
    评分 4 &sol; 5

    James Oli*** –

    “As a health care product brand, aiherba.com’s ODM solution gives us peace of mind. They provide complete raw material traceability files. For example, the latest batch of Ganoderma lucidum triterpenoid extract can be traced from the planting to the extraction process of the organic base in Yunnan. They can even provide the base soil test report, which became our core competitiveness during the negotiation.”

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