Beta arbutina

Beta Arbutin: Premium Skin Brightening Agent for Cosmetic & Pharmaceutical Applications – Manufacturer & Exporter Guide

1. What is Beta Arbutin?
For cosmetic chemists and product developers seeking a superior skin brightening solution, Beta Arbutin represents the gold standard in tyrosinase inhibition. This pure, single-isomer compound (4-Hydroxyphenyl-β-D-glucopyranoside) is the most effective and stable form of arbutin, specifically designed for high-performance skincare formulations. Unlike mixed alpha/beta extracts, our Beta Arbutin offers predictable results and exceptional formulation stability, making it the preferred choice for professional skincare brands and pharmaceutical applications.

2. Fonte, Química e Especificações

• Fonte: Synthesized through enzymatic biotransformation of hydroquinone and glucose

• Chemical Identity: Pure β-anomer of arbutin

• Perfil químico:

  • Nº CAS: 497-76-7

  • MF: C₁₂H₁₆O₇

  • MW: 272,25 g/mol

  • EINECS: 207-850-3

• Aparência: Pó cristalino branco a esbranquiçado

• Solubilidade: Highly soluble in water (≥50 g/100mL), slightly soluble in ethanol

• Pureza: ≥99% (CLAE)

3. The Formulator’s Choice: Why Pure Beta Arbutin Outperforms
Para Clientes B2B in cosmetic and pharmaceutical manufacturing, ingredient selection impacts final product efficacy and market success:

• Key Advantage: Pure β-anomer configuration ensures optimal tyrosinase inhibition and formulation stability

• Clinical Efficacy:

  • Superior Skin Brightening: 3x more effective than alpha-arbutin in melanin reduction

  • Hyperpigmentation Control: Significantly reduces dark spots and age spots

  • Even Skin Tone: Promotes uniform pigmentation and radiant complexion

• Recommended Usage: 1-3% in leave-on products, 3-5% in rinse-off formulations

• Compliance Status: Complies with EU Cosmetics Regulation, FDA guidelines, and ASEAN cosmetic standards

• Optimal Applications: Serums, creams, lotions, spot treatments, and pharmaceutical depigmenting products

• Perfil de segurança: Non-irritating, non-sensitizing, and photostable with excellent consumer tolerance

4. Zhonghong Biotech: Your Technical Partner in Skin Brightening Solutions
Sourcing reliable Beta Arbutin requires a partner with pharmaceutical-grade capabilities. 陕西中宏投资科技有限公司 (Shaanxi Zhonghong Investment Technology Co., Ltd.) combines 28 years of biochemical expertise with state-of-the-art manufacturing to deliver premium active ingredients for global markets.

• Technical Capabilities:

  • Enzymatic Synthesis: Proprietary biotransformation process ensures highest purity

  • Análise avançada: HPLC-ELSD, NMR, and mass spectrometry for precise characterization

  • University Collaborations: Joint research with 5 leading institutions for continuous innovation

• Conformidade global: Full documentation package including COA, MSDS, and regulatory support

5. Scientific Mechanism: Precision Tyrosinase Inhibition
Beta Arbutin’s efficacy stems from its specific molecular interaction with tyrosinase:

• Competitive inhibition of tyrosine hydroxylase and DOPA oxidase activities

• Structural similarity to tyrosine enables targeted enzyme binding

• Glucosidic bond prevents spontaneous hydroquinone release

• pH-stable performance across formulation matrices (pH 3.5-7.0)

6. Garantia de qualidade de nível farmacêutico
Our rigorous quality control ensures every batch meets the highest standards:

Certificate of Analysis (COA) Summary – Beta Arbutin (≥99%)

7. Processo de Fabricação Avançado
Our cGMP-compliant synthesis ensures superior quality:

1. Enzyme Selection: Proprietary β-glucosidase optimization

2. Biotransformation: Controlled enzymatic reaction under optimized conditions

3. Purificação: Multi-stage crystallization and chromatography

4. Cristalização: Precision crystallization for consistent particle size

5. Secagem: Vacuum drying at controlled temperatures

6. Controle de qualidade: Comprehensive analytical testing

8. Aplicações Profissionais

• Cosmecêuticos: Brightening serums, age spot correctors, evening treatments

• Produtos farmacêuticos: Melasma and hyperpigmentation treatments

• Professional Products: Clinical skincare and aesthetic formulations

• Personal Care: Whitening toothpaste and body care products

9. Global Supply Chain Excellence

• Embalagem: 1kg double-bagged with oxygen scavengers, 25kg fiber drums

• Armazenar: Cool, dry conditions (15-25°C) in original packaging

• Estabilidade: 24 months when stored properly

• Logística: Global express shipping with full documentation support

10. Technical Partnership Opportunities
Oferecemos:

• Custom purity grades (97%, 99%, 99.5%)

• Formulation technical support

• Regulatory documentation package

• Stability and compatibility studies

Contact Our Technical Team:

• Rede: www.aiherba.com

• E-mail: vendas@aiherba.com; liaodaohai@gmail.com

• Palavras-chave: Beta Arbutin supplier, skin whitening ingredient manufacturer, bulk arbutin, cosmetic active ingredients, pharmaceutical raw materials, Fabricante cGMP, cosmetic ingredient exporter

11. Technical FAQ

• Q: What’s the difference between alpha and beta arbutin?
  A: Beta arbutin is the natural, more stable form with proven efficacy, while alpha is synthetic and less stable

• Q: Can you provide hydroquinone-free certification?
  A: Yes, we guarantee ≤1 ppm hydroquinone in all batches

• P: Que documentação você fornece?
  A: Full COA, MSDS, stability data, and regulatory support documents

• Q: Do you offer formulation support?
  A: Our technical team provides comprehensive application support

• Q: What’s your typical lead time for large orders?
  A: 2-3 weeks for standard orders, 4-5 weeks for custom requirements

12. Conclusão Profissional
Beta Arbutin remains the gold standard for safe and effective skin brightening in professional formulations. Zhonghong’s pharmaceutical-grade manufacturing and technical expertise ensure consistent quality and performance for demanding cosmetic and pharmaceutical applications.

Contact us today for technical documentation and samples.

Referências:

1. Maeda, K., & Fukuda, M. (1996). Arbutin: mechanism of its depigmenting action in human melanocyte culture. Revista de Farmacologia e Terapêutica Experimental

2. Sugimoto, K., et al. (2005). Synthesis of α-arbutin and its comparison with β-arbutin. Biociências, Biotecnologia e Bioquímica

3. JECFA (2008). Safety evaluation of arbutin. WHO Food Additives Series

4. SCCS (2015). Opinion on arbutin. Scientific Committee on Consumer Safety