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Polygonum cuspidatum

Polygonum Cuspidatum Extract | Natural Resveratrol Supplier 

  1. English Name: Polygonum cuspidatum (also known as Japanese Knotweed)
  1. Specification
    • Resveratrol Content: ≥ 5% (HPLC, for standardized extract)
    • Solubility: Extract is partially soluble in water; root powder is sparingly soluble in water
    • Moisture Content: ≤ 10% (dried root); ≤ 5% (extract powder)
    • Heavy Metals: ≤ 10 ppm
    • Ash Content: ≤ 8%
  1. Appearance: Dried roots are brown to reddish-brown, cylindrical with a knotty surface; extract is brown to dark brown powder, with a characteristic herbal aroma
  1. CAS NO.: N/A (plant species); Key component Resveratrol: 501-36-0
  1. Lead time: 3 – 7 Working Days
  1. Package: Dried roots: 1 kg/bag, 25 kg/sack; Extract powder: 1 kg/aluminum foil bag, 25 kg/drum
  1. Main Market: Europe, North America, Asia, etc.
  1. Application Scenarios

Key Properties

  • Antioxidant: Rich in resveratrol and polyphenols that scavenge free radicals, protecting cells from oxidative damage
  • Anti-inflammatory: Inhibits inflammatory enzymes and cytokines, reducing inflammation
  • Cardioprotective: May support cardiovascular health by promoting healthy blood flow and reducing oxidative stress
  • Skin-protective: Helps protect the skin from environmental damage and supports skin health
  • Liver-protective: Exhibits potential in supporting liver function and detoxification

Application Scenarios

  1. Dietary Supplements
    • Antioxidant Support: Used in capsules and tablets (50 – 200 mg per serving) to provide antioxidant benefits
    • Cardiovascular Health: Included in formulations targeting heart health
    • Anti-aging Supplements: Added to blends for its potential anti-aging effects
  1. Functional Food and Beverages
    • Functional Drinks: Added to herbal teas, juices, and energy drinks for its health-promoting properties
    • Nutraceuticals: Incorporated into health bars and powders to enhance their nutritional value
  1. Cosmetics
    • Anti-aging Products: Used in creams and serums (0.5 – 2% concentration) for its antioxidant effects, helping to reduce signs of aging
    • Skin-protective Formulations: Included in products to protect the skin from environmental stressors
  1. Pharmaceutical Research
    • Investigated for its potential in managing cardiovascular diseases and metabolic disorders
    • Studied for its anti-inflammatory properties in treating various inflammatory conditions
  1. Traditional Medicine
    • Used in traditional Chinese medicine for addressing issues like joint pain, digestive problems, and skin conditions

Detection Methods

  • HPLC: For resveratrol analysis, Column C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Methanol – water (40:60), Flow Rate: 1.0 mL/min, Detection Wavelength: 306 nm
  • UV-Vis Spectroscopy: For total phenolic content determination at 765 nm
  • Thin-Layer Chromatography (TLC): Used for qualitative identification of key components

Advantages

  • Natural Source: Derived from the roots of Polygonum cuspidatum, a plant with a long history of use in traditional medicine
  • Rich in Bioactive Compounds: Contains resveratrol, emodin, and other beneficial substances with multiple health effects
  • Versatile Applications: Suitable for use in dietary supplements, cosmetics, and pharmaceutical research
  • Market Demand: Growing interest due to its antioxidant and potential health-promoting properties

Polygonum Cuspidatum Extract | Natural Resveratrol Supplier & OEM Factory

Bulk Supply | OEM & ODM Manufacturer | High-Purity Plant Extracts | AIHerba®


1. Product Overview

Product Name: Polygonum Cuspidatum Extract
Botanical Name: Polygonum cuspidatum Sieb. et Zucc.
Active Ingredient: Resveratrol (≥50%, 98%)
Other Components: Emodin, Polydatin, Anthraquinones
Appearance: Brown to white fine powder (depending on purity)
Part Used: Root
CAS No.: 501-36-0
Test Method: HPLC
Manufacturer: AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.
Certifications: GMP, ISO9001, ISO22000, HACCP, HALAL, KOSHER

Polygonum Cuspidatum Extract, commonly known as Japanese Knotweed Extract, is a rich natural source of trans-resveratrol—a potent antioxidant widely used in cosmetics, pharmaceuticals, and dietary supplements for anti-aging, cardiovascular protection, and inflammation control.


2. Origin & Production

AIHerba® sources Polygonum Cuspidatum roots from high-altitude areas of Shaanxi and Sichuan, China, ensuring sustainable and pesticide-free raw materials.
Extraction is carried out using water–ethanol extraction and low-temperature vacuum concentration to preserve bioactive integrity.

Production Process Flow

  1. Raw material cleaning & slicing

  2. Water–ethanol extraction

  3. Filtration & concentration

  4. Solvent recovery

  5. Chromatographic purification

  6. Spray drying or vacuum drying

  7. Quality control & standardization

  8. Packaging under GMP environment


3. Specifications & COA Summary

Item Specification Test Method
Appearance Brown or white fine powder Visual
Odor Characteristic Organoleptic
Assay (Resveratrol) ≥50% / 98% HPLC
Loss on Drying ≤5.0% AOAC 925.10
Ash ≤3.0% AOAC 923.03

Pesticide Residue Test

Item Limit (mg/kg) Test Method
Organochlorine pesticides (DDT, BHC) <0.1 GC-MS
Organophosphorus pesticides <0.1 GC-MS
Carbamates <0.1 LC-MS/MS
Pyrethroids <0.1 GC-MS

Heavy Metals

Item Limit (ppm) Test Method
Lead (Pb) ≤3.0 ICP-MS
Arsenic (As) ≤2.0 ICP-MS
Cadmium (Cd) ≤1.0 ICP-MS
Mercury (Hg) ≤0.1 ICP-MS

Microbiological Test

Item Limit Test Method
Total Plate Count ≤1,000 cfu/g USP <61>
Yeast & Mold ≤100 cfu/g USP <61>
E. coli Negative USP <62>
Salmonella Negative USP <62>
Staphylococcus aureus Negative USP <62>

4. Health Benefits & Mechanisms

  1. Antioxidant & Anti-aging – Neutralizes free radicals, supports cellular repair, and promotes longevity.

  2. Cardiovascular Health – Improves blood circulation and protects against oxidative stress in arteries.

  3. Anti-inflammatory Effects – Modulates cytokines and reduces inflammation pathways.

  4. Neuroprotective Support – May enhance cognitive function and delay neurodegenerative processes.

  5. Skin Health – Resveratrol promotes collagen synthesis and reduces UV-induced skin damage.

  6. Metabolic Regulation – Supports healthy glucose metabolism and weight management.


5. Traditional Applications

In Traditional Chinese Medicine (TCM), Polygonum Cuspidatum (Hu Zhang) has been used for:

  • Clearing heat and detoxifying the body

  • Promoting blood circulation

  • Treating liver disorders and inflammation

  • Healing wounds and insect bites


6. Application & Dosage Guidelines

Application Field Recommended Use Level Formulation Examples
Dietary Supplements 50–500 mg/day Capsules, Tablets
Functional Foods 0.1–1% Beverages, Nutritional Bars
Cosmetics 0.1–0.5% Anti-aging creams, Serums
Pharmaceuticals As per formulation Cardiovascular, Anti-inflammatory products

Best Formulation Synergies:

  • Combine with Vitamin C, Coenzyme Q10, or Hyaluronic Acid for anti-aging.

  • Blend with Green Tea Extract for enhanced antioxidant potency.


7. Storage & Shelf Life

  • Storage: Keep in a cool, dry, and dark place (below 25°C).

  • Shelf Life: 24 months from date of manufacture when properly sealed.

  • Packaging: 1kg/aluminum foil bag; 25kg/drum (customizable).


8. Logistics & Ordering Information

Item Details
MOQ 1 kg
Sample Policy Free 20–50g sample available
Lead Time 3–5 working days for sample; 7–15 days for bulk
Shipping Options DHL, FedEx, UPS, air, or sea freight
Customization OEM/ODM formula support & private labeling available

9. Applicable Industries & Use Cases

  • Nutraceuticals: Anti-aging, cardiovascular, antioxidant formulations

  • Cosmetics: Skin whitening, anti-aging, sun-protection products

  • Pharmaceuticals: Anti-inflammatory and liver protection agents

  • Food & Beverage: Functional drinks, antioxidant gummies

  • Animal Health: Antioxidant and immune-support formulations


10. Quality, Expertise & Certifications

Factory Experience: Over 28 years of R&D and manufacturing experience
Certifications: GMP, ISO9001, HACCP, HALAL, KOSHER
Analytical Reports: HPLC, ICP-MS, Microbial test data available
Quality Control: In-house lab + Third-party testing (SGS, Eurofins, CNAS)
Sustainability: Eco-friendly extraction, traceable supply chain


11. Frequently Asked Questions (FAQ)

Q1: Is AIHerba’s Polygonum Cuspidatum Extract natural or synthetic?
A1: 100% natural plant extract, derived from Polygonum cuspidatum roots via water–ethanol extraction.

Q2: Can I get a COA and MSDS before purchase?
A2: Yes, full COA, MSDS, and third-party test reports are provided upon request.

Q3: What’s the difference between 50% and 98% resveratrol content?
A3: 50% extract is brown and suitable for food & supplements; 98% is white crystalline powder for premium formulations.

Q4: Do you support customized formulations?
A4: Yes. AIHerba provides OEM/ODM solutions for capsules, tablets, beverages, and skincare applications.

Q5: How is purity and stability ensured?
A5: Controlled drying temperature (<60°C) and HPLC verification ensure high purity and stability.


12. References

  1. PubMed: Resveratrol and cardiovascular protection

  2. NIH: Resveratrol as an anti-aging compound

  3. FDA GRAS Notice on Resveratrol


13. Contact Us

AIHerba® | Shaanxi Zhonghong Investment Technology Co., Ltd.
📍 Address: Xi’an, Shaanxi, China
📧 Email: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 Website: www.aiherba.com

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