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트리테르페노이드

Triterpenoids factory supplier bulk Wholesale Extract factory

  1. 제품 개요
    English Name: Triterpenoids
    Source: Triterpenoids are a large class of natural compounds found in various plants, fungi, and some animals. They are synthesized through the mevalonate pathway in living organisms. Common sources include plants like ginseng, licorice, and fungi such as Poria cocos.
  2. 사양:Purity: Total Triterpenoids ≥ 95% (HPLC – tested). The extraction process depends on the source material. For plant – derived triterpenoids, methods like solvent extraction (using ethanol, methanol, etc.) are often employed, followed by purification through chromatography techniques (e.g., silica gel column chromatography, high – performance liquid chromatography). Stringent quality control measures are in place to limit heavy metals, pesticides, and microbial contaminants, ensuring compliance with international standards for different applications.
  3. 모습:Triterpenoids typically appear as white to off – white powders or colorless to pale – yellow crystals. They may have a faint, characteristic odor depending on the source. The powder or crystals are free – flowing, making them suitable for incorporation into different products.
  4. CAS 번호:Since triterpenoids are a class of compounds, there is no single CAS number. Each individual triterpenoid, such as betulinic acid (CAS NO.: 472 – 15 – 1) or oleanolic acid (CAS NO.: 508 – 02 – 1), has its own unique CAS number for chemical identification, research, and regulatory compliance.
  5. 리드타임:Lead time: 3 – 7 Working Days. Minor adjustments may occur based on order volume and production capacity. Our efficient production and logistics systems are designed to ensure timely delivery. However, factors such as the availability of raw materials (seasonal for some plants) or any production – related issues may slightly impact the lead time.
  6. 패키지: 일반적으로 25kg 식품 등급 드럼에 포장되며, 편리한 운송을 위해 트레이당 27개의 드럼이 들어 있습니다. 드럼은 보관 및 운송 중 습기, 빛, 그리고 물리적 손상으로부터 제품을 보호하는 재질로 제작되었습니다. 실험실용 소형 용기부터 산업용 대용량 용기까지, 고객 맞춤형 포장 옵션도 요청 시 제공됩니다.
  7. 주요 시장: European, North America, Asia etc. In Asia, especially in countries with a strong traditional medicine background, triterpenoids from plants like ginseng have been used for centuries. In Europe and North America, with the growing interest in natural health products, triterpenoids are gaining popularity.
  8. 응용 프로그램
    • 건강 보충제:
      • Anti – inflammatory: Many triterpenoids exhibit anti – inflammatory properties. They can inhibit the production of inflammatory mediators like cytokines and prostaglandins in the body. This is beneficial for conditions such as arthritis, where they can reduce joint inflammation and pain, and inflammatory bowel disease, by soothing the inflamed intestinal lining.
      • Antioxidant: Acting as antioxidants, triterpenoids can scavenge free radicals, protecting cells from oxidative damage. This can contribute to overall health and potentially reduce the risk of chronic diseases like heart disease, cancer, and neurodegenerative disorders.
      • Immune System Modulation: Some triterpenoids can modulate the immune system. They may enhance the activity of immune cells such as macrophages, T – lymphocytes, and B – lymphocytes, strengthening the body\’s defense against infections and diseases.
    • 화장품:
      • 피부 진정: 항염 효과가 있어 자극받은 피부를 진정시키는 데 효과적입니다. 여드름, 습진, 건선과 같은 피부 질환으로 인한 발적, 가려움, 염증을 완화하는 데 도움이 됩니다.
      • Anti – aging: By protecting skin cells from oxidative stress, triterpenoids help reduce the appearance of fine lines, wrinkles, and age spots. They may also enhance skin elasticity.
    • 식품 산업:
      • Functional Foods: Triterpenoids can be added to functional foods such as health drinks, energy bars, and fortified snacks. These products can provide consumers with the added health benefits of triterpenoids. However, their use in the food industry is subject to strict regulatory approvals to ensure safety and proper dosage.
      • Natural Preservative: Some triterpenoids may have antibacterial and antifungal properties, which could potentially be used to extend the shelf – life of certain food products. But this application requires further research and regulatory clearance.

Premium Triterpenoids: Nature’s Bioactive Powerhouses for Health & Innovation| Supplier & Manufacturer

1. 제품 소개

Triterpenoids represent a class of cyclic organic compounds comprising 30 carbon atoms with diverse pharmacological activities. As secondary metabolites predominantly found in medicinal plants and fungi, these compounds exhibit:

  • Structural diversity: Over 20,000 identified variants including oleanane, ursane, and lupane skeletons

  • Bioactivity spectrum:

    • Cytotoxic (IC50 values as low as 0.8μM against cancer cell lines)

    • Anti-inflammatory (COX-2 inhibition up to 92% at 50μg/mL)

    • Hypoglycemic (PPARγ activation at EC50 3.2nM)

우리의 GMP-certified triterpenoid portfolio 포함 사항:

  • Betulinic acid (≥98.5%, White powder)

  • Oleanolic acid (≥99%, USP grade)

  • Ursolic acid (≥98%, Kosher certified)

  • Specialty blends: Custom ratios for synergistic formulations


2. 회사 개요: 산시 중홍 투자 기술 유한회사

Core Differentiators

Competitive Edge 기술 사양
Academic Network Joint R&D with CAS, MIT, and ETH Zurich
IP 포트폴리오 27 patents including nano-encapsulation technologies
분석 능력 800MHz NMR with cryoprobe, UPLC-QTOF-MS/MS
규정 준수 DMF filings for US/EU/JP markets

Production Capacity:

  • 200+ metric tons/year across 15 triterpenoid compounds

  • Purity benchmarks: Consistently 15-25% above USP/EP monographs


3. Botanical Sources & Sustainable Sourcing

Primary Plant Sources

Triterpenoid 식물성 출처 Yield Optimization
Betulinic acid Betula platyphylla bark Supercritical CO₂ extraction (92% recovery)
Asiatic acid 센텔라 아시아티카 leaves Enzyme-assisted extraction (45% yield boost)
Ganoderic acids 영지버섯 mycelium Submerged fermentation technology

Sustainability Practices:

  • Wild-simulated cultivation: 3-year rotation cycles

  • Blockchain traceability: From soil to final product


4. Clinically Validated Health Benefits

기전적 약력학

Compound Target Pathway Therapeutic Application
Corosolic acid GLUT4 translocation Type II diabetes management
Madecassic acid TGF-β/Smad signaling Anti-fibrotic therapy
Glycyrrhetinic acid 11β-HSD2 inhibition Dermatological formulations

Dosing Guidelines:

  • 건강기능식품: 50-500mg/day in divided doses

  • Topicals: 0.1-5% w/w depending on indication

  • IV formulations: Strictly for clinical use under supervision


5. 제약 등급 사양

Comprehensive QC Parameters

Table 1: Triple-Verification Quality Standards

범주 매개변수 사양 방법
살충제 클로르피리포스 ≤0.01ppm GC-MS/MS(EU 396/2005)
피레트로이드 ≤0.05ppm 환경보호청 8081B
중금속 ≤0.5ppm ICP-MS(USP <232>)
CD ≤0.2ppm GF-AAS
미생물학 Total aerobic count ≤1000 CFU/g USP <61>
살모넬라균 25g에는 없음 ISO 6579

6. 고급 생산 워크플로

  1. Plant Material Authentication:

    • DNA barcoding (ITS2/rbcL markers)

    • Microscopic identification

  2. Green Extraction Technologies:

    • 아임계수 추출: 120-180°C, 50 bar

    • Ionic liquid-assisted extraction: [BMIM]BF4 system

  3. Purification Cascade:

    • Macroporous resin chromatography (HPD-826 resin)

    • Preparative HPLC (C30 columns for isomer separation)

  4. Crystallization Control:

    • Polymorph screening (Forms I-V characterization)

    • Controlled nucleation technology


7. 최첨단 애플리케이션

Emerging Market Utilization

  • 종양학: Betulinic acid-PLGA nanoparticles (Phase II trials)

  • 코스메슈티컬: Ursolic acid liposomes for transdermal delivery

  • 수의사: Oleanolic acid as hepatoprotective in livestock

Formulation Technologies:

  • 나노에멀젼: 50-200nm particle size for enhanced bioavailability

  • Cocrystals: With nicotinamide for solubility enhancement


8. Quality Management Ecosystem

우리의 360° quality assurance incorporates:

  • Stability Indicating Methods: Forced degradation per ICH Q1A(R2)

  • 원소 불순물: Full suite USP <232>/<233> compliance

  • Chiral Purity: ≥99% ee by chiral HPLC (Chiralpak IC column)

  • 잔류 용매: Class 1-3 monitoring per ICH Q3C

안정성 데이터:

  • Accelerated conditions: 40°C/75% RH, 6-month stability confirmed

  • 장기적으로: 36-month shelf life at -20°C


9. Intelligent Packaging Systems

Format 패키징 솔루션 Special Features
Bulk (>10kg) Nitrogen-flushed aluminum foil bags Oxygen ingress <0.1% over 24 months
Clinical samples Amber glass vials with Teflon septa USP Class VI certified
수송 Vacuum-insulated shippers 2-8°C maintenance for 120h

10. Research Frontiers & Technical Challenges

혁신 파이프라인

  • Biocatalytic Modification: P450 engineering for novel derivatives

  • AI-assisted Discovery: Predicting structure-activity relationships

기술적 장애물

  • 경구 생체이용률: Typically <15% for most triterpenoids

  • 대사산물 식별: Phase II conjugation patterns


11. 전문가 FAQ

Q: What’s your MOQ for research samples?
A: 100mg available for academic institutions with COA.

Q: Can you provide customized glycosylation profiles?
A: Yes, we offer β-glucuronidase treated variants upon request.


12. 결론

우리의 GMP-certified triterpenoid platform 결합하다 centuries of traditional use ~와 함께 21st century analytical rigor, delivering standardized bioactive compounds for next-generation therapeutics.

구매처 트리테르페노이드

We are your trusted partner for sourcing high-quality Triterpenoids

오늘 저희에게 연락해 조달 요구 사항을 논의하고, R&D용 무료 샘플을 요청하고, 경쟁력 있는 도매가를 받아보세요.


13. 권위 있는 참고문헌

  1. 천연물 저널 (2023) – Structural diversity review

  2. USP Monographs for Triterpenes (2024)

  3. EMA Assessment Reports on Herbal Substances

Pharmaceutical triterpenoids supplier, GMP-certified plant extracts, bioactive pentacyclic compounds, natural anti-inflammatory ingredients, high-purity ursolic acid

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