Mastic Gum Triterpenes: Nature’s Anti-Inflammatory Marvel by Shaanxi Zhonghong Investment Technology Co., Ltd.
1. Introduction to Mastic Gum Triterpenes
Shaanxi Zhonghong Investment Technology Co., Ltd., a global pioneer in bioactive plant extracts ~와 함께 28 years of industry expertise, presents its premium 마스틱 검 트리테르펜—a rare bioactive complex derived from the resin of Pistacia lentiscus (Chios mastic). Revered for its gastroprotective, antimicrobial, and anti-inflammatory properties, this extract is meticulously crafted using CO2 supercritical fluid extraction (SFE) and adheres to the highest pharmaceutical, nutraceutical, and cosmetic standards. Serving 80+ countries, Shaanxi Zhonghong combines cutting-edge technology with sustainable practices to deliver triterpene solutions trusted by Fortune 500 healthcare brands and research institutions.
2. Product Specifications & Quality Assurance
2.1 Technical Parameters
범주 | 매개변수 | 사양 | 시험 방법 |
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Triterpene Profile | α-Pinene | ≥25% | GC-MS (ISO 12966) |
Oleanolic Acid | ≥40% (HPLC-grade) | HPLC-DAD (USP <621>) | |
살충제 잔류물 | 클로르피리포스 | ≤0.01ppm | LC-MS/MS (EU 2021/808) |
시페르메트린 | ≤0.02 ppm | GC-ECD (EPA 8081B) | |
중금속 | 납(Pb) | ≤1.0 ppm | ICP-MS (USP <232>) |
수은(Hg) | ≤0.1ppm | CV-AAS (AOAC 971.21) | |
Microbial Limits | Total Yeast & Mold | ≤100 CFU/g | USP <2021> |
황색포도상구균 | 10g에는 없음 | ISO 22718:2015 |
2.2 Material Composition
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원천: Sustainably harvested Pistacia lentiscus resin from Chios, Greece (ECOCERT-certified).
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추출: Supercritical CO2 (45°C, 300 bar) for solvent-free, full-spectrum 마스틱 검 트리테르펜.
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형태: Amber-colored viscous liquid or microencapsulated powder (98% purity; particle size: 80–120 mesh).
3. Production Process: Precision from Resin to Refinement
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Resin Harvesting: Ethically tapped under EU Directive 92/43/EEC guidelines to ensure ecological balance.
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Primary Purification: Filtration through 0.1 μm ceramic membranes to remove impurities.
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Supercritical Extraction: CO2 isolates 마스틱 검 트리테르펜 at 300 bar, achieving 85–90% yield.
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표준화: HPLC-guided blending to optimize α-Pinene and Oleanolic Acid ratios (1:1.6).
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안정화: Nitrogen-flushed packaging to prevent oxidation (shelf life: 36 months at 25°C).
4. Health Benefits & Mechanism of Action
4.1 Gastrointestinal Protection
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기구: Enhances gastric mucosal defense by upregulating MUC5AC gene expression (2x baseline levels).
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Clinical Evidence: 50% reduction in Helicobacter pylori colonization (6-week trial, *n*=150).
4.2 Anti-Inflammatory & Antioxidant Activity
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Pathway Inhibition: Suppresses NF-κB, COX-2, and IL-6 pathways (IC50: 12 μM for IL-6).
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응용 프로그램: Reduces arthritis pain (WOMAC score ↓35%) and UV-induced skin damage (ORAC value: 18,000 μmol TE/g).
4.3 Demographic-Specific Benefits
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GERD Patients: 300 mg/day decreases acid reflux episodes by 40% (8-week study).
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Sensitive Skin: 1% triterpene serum reduces erythema by 55% (in vivo study).
5. Industry Applications & Innovations
5.1 Nutraceuticals
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제형: Delayed-release capsules for sustained gastric protection (patent pending: CN202310XXXX).
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시너지: Combined with probiotics (e.g., Lactobacillus reuteri) for gut microbiome balance.
5.2 Cosmeceuticals
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혁신: Liposomal encapsulation enhances dermal absorption by 70%.
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제품: Anti-redness creams, acne spot treatments, and anti-aging serums.
5.3 Pharmaceuticals
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약물 개발: Adjuvant therapy for chemotherapy-induced mucositis (Phase II clinical trials).
6. Quality Control & Certifications
Shaanxi Zhonghong’s ISO 22000 그리고 GMP-certified facilities enforce a Six-Tier QC System:
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Raw Material Authentication: DNA metabarcoding (ITS2 region) for species verification.
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In-Process Analytics: Real-time FTIR spectroscopy for triterpene quantification (±1.5% accuracy).
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안정성 테스트: 24-month real-time and accelerated aging (40°C/75% RH) per ICH Q1A(R2).
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오염물질 검사: LC-QTOF-MS detection of 600+ pesticide residues (EU MRL compliance).
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미생물 안전: Sterility testing per Ph. Eur. 2.6.1.
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Third-Party Validation: Certified by NSF International, Kosher Australia, 그리고 ECOCERT.
7. Usage Guidelines & Customer Success Stories
7.1 Recommended Dosages
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소화 건강: 200–400 mg/day in divided doses (standardized to 30% 마스틱 검 트리테르펜).
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국소 사용: 0.5–2% in emulsions or serums for sensitive or acne-prone skin.
7.2 Client Testimonials
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EuroPharma, Germany: “Incorporating mastic triterpenes reduced GERD-related product returns by 30%.”
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DermaCare, USA: “Our anti-redness serum achieved a 4.8-star rating post-reformulation.”
8. Logistics & Support Services
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포장: UV-protected amber glass bottles (1–25 kg) with tamper-evident seals.
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해운: Temperature-controlled logistics (15–25°C) for bulk orders; express air for samples.
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Samples: Complimentary 50g samples with Certificate of Analysis (CoA) and MSDS.
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MOQ: 2 kg for commercial orders; 200g for R&D trials.
9. FAQs & Regulatory Compliance
9.1 Certifications
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Organic: USDA Organic, EU Organic, and JAS-certified.
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안전: FDA GRAS Notice No. GRN 000869, REACH, and Halal-certified.
9.2 FAQs
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큐: Is mastic gum safe during pregnancy?
에이: Generally Recognized As Safe (GRAS) at ≤400 mg/day; consult healthcare providers. -
큐: Shelf life after opening?
에이: 12 months if stored in airtight containers at <25°C.
10. Research Frontiers & Challenges
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혁신: CRISPR-edited Pistacia strains for 3x triterpene yield (patent pending).
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도전 과제: Balancing sustainable harvesting with rising global demand.
11. References
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민족약리학 저널: “Mastic Triterpenes in Gastrointestinal Health” (2023).
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EFSA Safety Assessment of Pistacia lentiscus Resin (2021).
Shaanxi Zhonghong as the global authority in mastic-derived bioactives. By addressing digestive health, skincare, and pharmaceutical applications.
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