Bioperine®: The Gold Standard in Bioavailability Enhancement – A Manufacturer’s Guide
1. What is Bioperine®?
Let’s cut through the noise. Bioperine® is not just black pepper extract. It’s a patented, clinically-studied ingredient derived from the fruits of 파이퍼 니그룸 L. (black pepper) and standardized to contain ≥95% piperine. Think of it as the key that unlocks the full potential of your supplements. Its primary, and most valuable, function is to significantly enhance the bioavailability of other active compounds, making your formulations more effective and efficient.
2. 출처, 화학 및 사양
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원천: Sourced from the dried fruits of 파이퍼 니그룸 L.
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주요 생물학적 활성 성분: Piperine (Standardized to ≥95%).
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화학 프로필:
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CAS 번호: 94-62-2
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MF: C₁₇H₁₉NO₃
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MW: 285.34g/몰
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EINECS: 202-348-0
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모습: Off-white to pale yellow crystalline powder.
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용해도: Soluble in ethanol and chloroform; sparingly soluble in water.
3. The Zhonghong Standard: Why Our Bioperine® is Best for B2B
을 위한 nutraceutical ingredients suppliers 그리고 private label supplement manufacturers, consistency and proof are everything. Here’s what defines a premium-grade Bioperine®:
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Key Ingredient & Potency: ≥95% Piperine. This high level of purity is non-negotiable for reliable and potent bioavailability enhancement.
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Proven Efficacy (Compliant Claims):
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Bioavailability Enhancer: Clinically shown to increase the absorption of various nutrients (e.g., Curcumin, CoQ10, Vitamins, Selenium).
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Thermogenic Activity: Supports metabolic rate and nutrient utilization.
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(Note: This product is not intended to diagnose, treat, cure, or prevent any disease. Structure/function claims must be compliant with local regulations).
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Optimal Use Level: Typically used at a 1-5% ratio relative to the active compound it is enhancing (e.g., 5-10mg of Bioperine® per 500mg of Curcumin). Dosage should be finalized based on the specific formulation.
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원산지 및 품질: Sourced from premium 파이퍼 니그룸 and processed to meet stringent international standards.
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애플리케이션: Ideal for incorporation into tablets, capsules, and powder formulations for dietary supplements.
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Target Formulations: Essential for private label supplement manufacturers creating products with high-value actives like turmeric/curcumin, resveratrol, multivitamins, and cognitive health blends.
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Safety & Considerations:
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일반적으로 안전하다고 인정됨(GRAS): At recommended levels.
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약물 상호작용: May affect the metabolism of certain pharmaceutical drugs by inhibiting cytochrome P450 enzymes and UDP-glucuronylation. Consult a medical expert if formulating for populations on medication.
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임신/모유수유: Recommended to avoid high doses.
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4. Zhonghong Biotech: Your Strategic Ingredient Partner
When you need a reliable bulk botanical extracts partner, you need more than a vendor. You need a technical expert. 산시 중홍 투자기술 유한회사 인증되었습니다 건강기능식품 성분 공급업체 with 28 years of experience in bioactive compound manufacturing.
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핵심 전문성: We are specialists in the precision extraction and purification of plant-derived actives. Our portfolio is built for B2B:
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Standardized Botanical Extracts (like Bioperine®)
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Cosmetic Raw Material Supplier offerings
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건강기능식품 성분 for supplements and functional foods
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API Intermediates
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Our B2B Value Proposition:
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Innovation-Driven: 20+ patents and university collaborations ensure we are at the forefront of extraction technology.
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품질 보증: Our investment in HPLC 및 NMR 분광법 guarantees a purity standard that is consistently 20% above common industry specs, providing you with a uncontested competitive edge.
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Global B2B Network: We supply 도매 식물 추출물 그리고 customized solutions 에게 OEM 허브 추출물 partners and major brands in over 80 countries.
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5. Technical Insight: Mechanism of Action
Piperine’s primary mechanism is two-fold:
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Inhibition of Metabolism: It inhibits the enzymes in the liver and intestine (e.g., CYP3A4, UGT) that would normally break down and eliminate other compounds before they enter the bloodstream.
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Enhancing Absorption: It stimulates amino acid transporters in the intestinal lining and increases blood supply to the GI tract, facilitating greater uptake of co-administered supplements.
6. Uncompromising Quality Control: The COA
Our Quality Control is your formulation’s insurance policy. Every batch is rigorously tested.
Certificate of Analysis (COA) Summary – Bioperine® (≥95% Piperine)
범주 | 매개변수 | 사양 | 시험 방법 |
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살충제 | 클로르피리포스 | ≤ 0.2mg/kg | GC-MS/MS |
시페르메트린 | ≤ 0.5mg/kg | GC-MS/MS | |
디클로르보스 | ≤ 0.1mg/kg | GC-MS/MS | |
(Full Suite) | (USP/EP에 따라) | GC-MS/MS / LC-MS/MS | |
중금속 | 납(Pb) | ≤ 3.0mg/kg | ICP-MS |
비소(As) | ≤ 2.0mg/kg | ICP-MS | |
카드뮴(Cd) | ≤ 1.0mg/kg | ICP-MS | |
수은(Hg) | ≤ 0.1mg/kg | ICP-MS | |
미생물학 | 총 플레이트 수 | ≤ 10,000 CFU/g | USP <61> |
효모 및 곰팡이 | ≤ 100 CFU/g | USP <61> | |
대장균 | 1g에서 음성 | USP <62> | |
살모넬라균 종 | 10g에서 음성 | USP <62> | |
일반적인 | Piperine Content | ≥ 95.0% | HPLC-UV |
건조 감량 | ≤ 5.0% | USP <731> | |
잔류 용매 | ICH Q3C를 충족합니다 | GC-FID |
7. Advanced Production Process
Our GMP-compliant process ensures unmatched purity:
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소싱 및 준비: Selection and cleaning of premium 파이퍼 니그룸 과일.
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추출: Solvent extraction optimized for maximum piperine yield.
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Filtration & Concentration: Removal of impurities and concentration of the extract.
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Crystallization & Purification: Further refinement to achieve the ≥95% purity benchmark.
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표준화: Precise adjustment to meet the exact specification.
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건조 및 제분: Conversion into a fine, free-flowing powder.
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QC 릴리스: The batch is only released after passing all critical quality parameters.
8. Application in Nutraceutical Formulations
This ingredient is a cornerstone for effective supplement design. Its primary application is in:
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Enhanced Absorption Formulas: Curcumin supplements, multivitamins, coenzyme Q10, resveratrol, and antioxidant blends.
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Weight Management Products: Leveraging its mild thermogenic properties.
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스포츠 영양: To improve the uptake of amino acids and other performance nutrients.
9. B2B Packaging & Logistics
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포장: Standard 25kg/fiber drum with double polyethylene liners. Customized packaging available for 모조리 그리고 대부분 명령.
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저장: Store in a cool, dry place away from strong light.
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유통기한: 24 months when stored correctly.
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기호 논리학: We handle global shipping and all export documentation (COA, MSDS, Certificate of Origin) for seamless delivery to OEM partners worldwide.
10. 대량 재료 필요 사항에 대해 저희와 협력하세요
Zhonghong isn’t just a 공급업체; we’re your innovation partner. We provide:
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경쟁력 있는 대량 가격: 직접 받으세요 공장 가격 대량 주문의 경우.
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Customization & OEM: 우리는 제공합니다 OEM 허브 추출물 그리고 customized solutions tailored to your specific formulation requirements.
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Technical Support: Leverage our 28 years of expertise for your product development.
견적이나 샘플을 요청하려면 저희에게 연락하세요!
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편물: www.aiherba.com
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키워드: Bioperine supplier, bulk piperine, nutraceutical ingredients supplier, cosmetic raw material supplier, wholesale botanical extracts, private label supplement manufacturer, OEM herbal extracts, bulk organic ingredients.
11. B2B 고객을 위한 FAQ
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Q: What is your Minimum Order Quantity (MOQ) for bulk orders?
A: 자세한 MOQ 정보는 문의해 주세요. 저희는 유연한 조건을 제공합니다. 모조리 그리고 대부분 파트너. -
Q: Can you provide custom standardization for private label?
A: Absolutely. As an OEM 허브 추출물 partner, we specialize in customized solutions to meet your specific product specs. -
Q: Do you offer technical documentation and regulatory support?
A: Yes. We provide full documentation (COA, MSDS) and can support with regulatory data for your market. -
Q: What is the lead time for large orders?
A: Lead times vary based on order size. We maintain strategic stock for popular items and provide clear timelines for custom productions. -
Q: How do I start the qualification process?
A: 이메일로 문의해주세요. sales@aiherba.com 요청하다 무료 샘플 and discuss your specific needs. Our technical team will guide you through the process.
12. 결론
In the competitive world of supplement manufacturing, ingredient efficacy is paramount. Bioperine® is a proven, powerful tool to differentiate your products and guarantee customer results. Sourcing from a technically advanced, reliable 제조업체 is critical. Zhonghong Biotech, with its scientific rigor, proven quality, and global B2B supply capability, is the optimal partner for nutraceutical ingredients suppliers 그리고 개인 상표 brands. Contact us today to discuss your project and request a sample.
참고문헌:
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Majeed, M., et al. (1999). Piperine, a bioavailability enhancer. US Patent 5,972,382.
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Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. 플랜타 메디카, 64(4), 353-356.
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Badmaev, V., et al. (2000). Piperine, an alkaloid derived from black pepper, increases serum response of beta-carotene during 14-days of oral supplementation. Nutrition Research, 20(3), 381-388.
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Johnson, J. J., et al. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. 분자 영양학 및 식품 연구, 55(8), 1169-1176.
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