Berberine Extract | High-Purity Botanical Ingredient Supplier | AIHerba®
1. 製品概要
英語名: ベルベリンエキス
植物由来: メギ・アリスタタ, オウレン (Coptis root), or キハダ 吠える
有効成分： Berberine Hydrochloride / Berberine Sulfate
仕様： 97% Berberine (HPLC)
外観： 黄色の結晶性粉末
CAS番号: 633-65-8
分子式: C₂₀H₁₈NO₄⁺
メーカー: 陝西中宏投資技術有限公司 (AIHerba®)
証明書: GMP、ISO9001、ISO22000、HACCP、ハラール、コーシャ
Berberine is a natural isoquinoline alkaloid extracted from オウレン and other Berberis plants. With potent bioactivity and a long history in traditional Chinese medicine, it is widely used in pharmaceuticals, dietary supplements, and functional food formulations for its glucose-regulating, antimicrobial, and metabolic benefits.
2. Source & Production
AIHerba® sources premium オウレン roots and メギ・アリスタタ barks from pollution-free mountain regions in China.
Production utilizes modern water-ethanol extraction, 超臨界CO₂精製、 そして membrane separation 確実にするため:
- ≥97% purity (HPLC verified)
- Low heavy metal and pesticide residue levels
- Consistent batch-to-batch quality
- Full traceability from raw herb to final extract
3. Health Benefits & Functions
(1) Key Bioactive Benefits
- 血糖値の調節: Supports insulin sensitivity and lowers fasting glucose levels.
- 脂質代謝: Reduces LDL cholesterol and triglycerides while increasing HDL.
- Gut Microbiome Support: Balances intestinal flora and improves digestive function.
- 抗炎症・抗酸化作用： Reduces systemic inflammation and oxidative stress.
- 心臓血管の健康: Promotes endothelial function and circulation.
(2) Scientifically Supported Health Effects
Clinical studies (NIH, PubMed) have shown berberine’s comparable effects to metformin in managing Type 2 diabetes and metabolic syndrome.
4. 従来のアプリケーション
何世紀にもわたって使用されてきた 伝統中国医学（TCM） as “Huang Lian,” berberine was prescribed to treat gastrointestinal infections, fever, and inflammation. In Ayurveda, メギ・アリスタタ (Tree Turmeric) was known for its cleansing and antimicrobial effects.
5. 推奨用量と使用方法
| 応用 | 典型的な投与量 | Usage Form |
|---|---|---|
| 栄養補助食品 | 500～1500 mg/日 | Capsules, Tablets, Powders |
| 機能性飲料 | 100–300 mg/serving | Dissolved or mixed in drink bases |
| 医薬品製剤 | カスタマイズ | Per regulatory and formulation requirements |
6. Best Formulation Combinations
Berberine is often combined with:
- Milk Thistle Extract (Silymarin): Enhances liver detoxification.
- Alpha Lipoic Acid: Boosts glucose metabolism.
- Cinnamon Extract: Improves insulin sensitivity.
- Probiotics: Supports microbiota balance and absorption efficiency.
7. Safety & Precautions
- Avoid during pregnancy or lactation without medical supervision.
- May interact with diabetic medications—consult a physician before use.
- Store in a cool, dry place away from direct light and moisture.
8. 技術仕様（COA概要）
| カテゴリ | アイテム | 仕様 | 試験方法 |
|---|---|---|---|
| 外観 | 黄色の結晶性粉末 | 適合 | ビジュアル |
| Assay (Berberine) | ≥97.0% | HPLC | |
| 乾燥減量 | ≤5.0% | 105°C, 2h | |
| 灰分含有量 | ≤2.0% | 重量法 | |
| 溶媒残留物 | ≤5000ppm | GC |
残留農薬検査
| アイテム | 限界値（ppm） | 方法 |
|---|---|---|
| DDT | <0.05 | GC-ECD |
| BHC | <0.05 | GC-ECD |
| パラチオン | <0.05 | GC-MS |
| カルボフラン | <0.05 | LC-MS/MS |
| クロルピリホス | <0.05 | GC-MS |
Heavy Metal Testing
| 金属 | 制限 | 方法 |
|---|---|---|
| 鉛（Pb） | ≤3.0 mg/kg | ICP-MS |
| ヒ素（As） | ≤2.0 mg/kg | ICP-MS |
| 水銀（Hg） | ≤0.1 mg/kg | ICP-MS |
| カドミウム（Cd） | ≤1.0 mg/kg | ICP-MS |
微生物学的検査
| パラメータ | 制限 | 方法 |
|---|---|---|
| 総皿数 | ≤1000 CFU/g | USP <61> |
| 酵母とカビ | ≤100 CFU/g | USP <61> |
| 大腸菌 | ネガティブ | USP <62> |
| サルモネラ | ネガティブ | USP <62> |
| 黄色ブドウ球菌 | ネガティブ | USP <62> |
9. 製造工程
- 原材料の選択 →
- Crushing & Pre-treatment →
- 水エタノール抽出 →
- ろ過と濃縮 →
- Purification (Membrane & Chromatography) →
- Drying (Spray or Vacuum Drying) →
- 粉砕とふるい分け →
- Quality Inspection & Packaging
All steps follow GMP、ISO、HACCP standards with full traceability.
10. 保管、賞味期限、包装
- ストレージ： Store below 25°C, in a tightly sealed container, protected from light and humidity.
- 貯蔵寿命： 製造日から24ヶ月。.
- パッケージ: 25 kg/drum (inner double PE bag + outer fiber drum).
- サンプル: Free 20–50 g samples available upon request.
- 最小注文数量: 1 kg (for trial order).
11. Logistics & Delivery
- リードタイム： 3–7 working days for standard specifications.
- 配送方法: DHL, FedEx, UPS, or air/sea freight.
- Customs Documentation: COA, MSDS, TDS, Non-GMO statement, and Origin Certificate available.
12. Application Industries
| 業界 | アプリケーション |
|---|---|
| 栄養補助食品 | Blood sugar control, lipid management supplements |
| 医薬品 | Metabolic and anti-inflammatory formulations |
| 機能性食品 | Metabolic health beverages, herbal tonics |
| 化粧品 | Antibacterial and anti-inflammatory skin formulations |
| Veterinary & Feed Additives | Natural antimicrobial ingredient |
13. Why Choose AIHerba®?
✅ Professional Factory: 以上 28年 of production experience in botanical extracts.
✅ 認定資格: GMP, ISO9001, ISO22000, HALAL, KOSHER.
✅ OEM/ODM Solutions: Custom formulations for global brands.
✅ Global Clients: Trusted by 1,000+ health and cosmetic companies.
✅ 完全なトレーサビリティ: Raw material to final batch with transparent quality control.
14. よくある質問（FAQ）
Q1: Is berberine water-soluble?
A1: Berberine hydrochloride is slightly soluble in water but dissolves better in ethanol and methanol.
Q2: Can I get customized specifications (e.g., 85% Berberine)?
A2: Yes. We provide tailored purity levels and formulation bases according to client needs.
Q3: What is the lead time for bulk orders?
A3: Typically 5–10 days depending on quantity and specification.
Q4: Can AIHerba provide third-party testing reports?
A4: Yes. We can provide SGS, Eurofins, or Intertek reports upon request.
15. 参考文献
- Yin, J. et al. “Efficacy of Berberine in Type 2 Diabetes Mellitus: A Meta-analysis.” 代謝 (2008). PubMed Link
- NIH: Berberine — Herbal Supplement Information. NIH.gov
- FDA Botanical Drug Development Guidance. FDA.gov
お問い合わせ
📧 メールアドレス: sales@aiherba.com | メールアドレス | liaodaohai@gmail.com
🌐 Webサイト： www.aiherba.com
🏭 工場： 陝西中宏投資テクノロジー株式会社
AIHerba® – Your Trusted GMP-Certified Natural Plant Extract Supplier in China
English 
العربية 
Čeština 
Deutsch 
Español de México 
Français 
हिन्दी 
Bahasa Indonesia 
日本語 
한국어 
Русский 
Italiano