Premium Frankincense Extract: Your Trusted Source for Bulk & Customized Solutions
1. What is Frankincense Extract?
Frankincense Extract, derived from the resin of Boswellia trees (primarily Boswellia serrata, Boswellia carterii), is a concentrated source of bioactive compounds, notably Boswellic Acids (KBA, AKBA). This potent extract is revered in traditional medicine systems (Ayurveda, Traditional Chinese Medicine) and is now a cornerstone of modern nutraceuticals, cosmeceuticals, and functional foods. Its primary value lies in modulating key inflammatory pathways and supporting cellular health.
2. Fonte, chimica e specifiche
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Botanical Source: Resin from Boswellia serrata (Indian Frankincense) or Boswellia carterii (Olibanum).
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Key Active Compounds: Acetyl-11-keto-β-boswellic acid (AKBA), 11-keto-β-boswellic acid (KBA), β-boswellic acid, other pentacyclic triterpenic acids.
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Proprietà chimiche:
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Numero CAS: 89958-55-6 (for Boswellic Acids mixture)
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Formula molecolare (MF): Variable (e.g., AKBA: C₃₂H₄₈O₅)
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Peso molecolare (MW): Variable (e.g., AKBA: 512.7 g/mol)
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EINECS: Typically listed under the specific compound or resin extract entry.
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Aspetto: Fine, free-flowing powder ranging from white to pale yellow or brown.
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Solubilità: Soluble in ethanol, dimethyl sulfoxide (DMSO); sparingly soluble in water; often used in oil-based formulations or encapsulated.
3. What is the Best Frankincense Extract? Key Selection Criteria
Choosing the optimal extract requires evaluating several critical factors:
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Standardization & Potency: The best extracts are standardized to key Boswellic Acids, particularly AKBA (e.g., 10%, 20%, 65%, 70% AKBA). Higher standardization ensures consistent biological activity. Zhonghong offers customizable standardization levels.
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Purity & Safety: Rigorous testing for contaminants (heavy metals, pesticides, microbes) is non-negotiable. Adherence to USP, EP, or relevant pharmacopoeia standards is essential. See our comprehensive COA table below.
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Extraction Technology: Advanced methods like Estrazione di CO2 supercritica O Patented Chromatographic Purification (Zhonghong’s specialty) yield superior purity, bioavailability, and preserve sensitive actives compared to basic solvent extracts.
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Origin & Sustainability: Ethically sourced resin from controlled regions ensures quality consistency and supports sustainable practices. Zhonghong imports premium-grade raw materials.
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Bioavailability: Formulations enhancing absorption (e.g., phospholipid complexes) offer greater efficacy.
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Manufacturer Reputation: Choose established suppliers like Zhonghong with proven expertise, regulatory compliance (ISO, GMP), and transparent quality control.
Health Benefits & Usage:
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Key Benefits (Supported by Research):
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Promotes Joint Comfort & Mobility: Modulates 5-LOX enzyme and inflammatory cytokines (TNF-α, IL-1β, IL-6).
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Supports Respiratory Wellness: Helps maintain clear airways.
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Enhances Skin Health: Soothes irritation and promotes a healthy complexion.
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Provides Cellular Protection: Exhibits antioxidant properties.
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Supports Healthy Digestion: Promotes gut lining integrity.
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Promotes Overall Inflammatory Balance.
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Typical Daily Intake: Dosage varies based on standardization (AKBA content) and application. Common ranges:
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Nutraceuticals: 100mg – 500mg of extract (standardized to 20-70% Boswellic Acids) 1-3 times daily. Consult a healthcare professional for personalized advice.
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Applications: Dietary supplements (capsules, tablets), functional foods & beverages, topical creams/serums, cosmetic actives.
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Target Users: Adults seeking joint, respiratory, skin, or general wellness support. Not recommended for children, pregnant or nursing women without medical advice.
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Safety & Side Effects: Generally well-tolerated. Mild gastrointestinal discomfort (heartburn, nausea, diarrhea) possible at high doses. Contraindicated with certain blood thinners. Always source from reputable suppliers adhering to strict safety protocols like Zhonghong.
4. Why Choose Shaanxi Zhonghong Investment Technology Co., Ltd.?
As a premier Frankincense Extract manufacturer, supplier, and factory, Zhonghong stands apart:
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28 Years of Bioactive Compound Excellence: Deep expertise in plant extraction for nutraceuticals, pharmaceuticals, and cosmetics.
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Cutting-Edge R&D: Collaborations with 5 top universities; 20+ proprietary patents; exclusive global compound library.
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Unmatched Quality Control: Investment in HPLC, UPLC-MS, GC-MS, and Superconducting NMR ensures purity exceeding industry standards by 20%+. Rigorous identity, potency, and contaminant testing.
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Advanced Production: Estrazione di CO2 supercritica, Macroporous Resin Adsorption, HPLC preparativa, E Cryogenic Grinding deliver premium purity and bioavailability.
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Portata globale: Trusted supplier to multinational pharma, nutraceutical brands, and research institutions across 80+ countries in Asia, Europe, and the Americas.
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Customization & Scale: Expertise in customized herbal extract solutions, from R&D samples to bulk industrial quantities. Reliable supply chain management.
5. Comprehensive Certificate of Analysis (COA) Specifications
Zhonghong’s Frankincense Extract meets stringent international safety standards:
Parameter Category | Test Item | Specification (Typical) | Metodo di prova |
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Residui di pesticidi | Aldrin & Dieldrin | ≤ 0,01 mg/kg | GC-MS/MS |
Chlordane (Total) | ≤ 0.03 mg/kg | GC-MS/MS | |
DDT (Total) | ≤ 0,05 mg/kg | GC-MS/MS | |
Esaclorobenzene | ≤ 0,01 mg/kg | GC-MS/MS | |
Hexachlorocyclohexane (HCH) | ≤ 0,01 mg/kg | GC-MS/MS | |
Heptachlor & Epoxide | ≤ 0,01 mg/kg | GC-MS/MS | |
metalli pesanti | Arsenico (As) | ≤ 1,0 mg/kg | ICP-MS |
Piombo (Pb) | ≤ 1,0 mg/kg | ICP-MS | |
Cadmio (Cd) | ≤ 0,5 mg/kg | ICP-MS | |
Mercurio (Hg) | ≤ 0,1 mg/kg | ICP-MS / CVAAS | |
Microbiologico | Total Aerobic Microbial Count | ≤ 1.000 UFC/g | USP <61>, EP 2.6.12 |
Total Yeast & Mold Count | ≤ 100 UFC/g | USP <61>, EP 2.6.12 | |
Escherichia coli | Assente in 1g | USP <62>, EP 2.6.13 | |
Salmonella specie | Assente in 10g | USP <62>, EP 2.6.13 | |
Stafilococco aureo | Assente in 1g | USP <62> |
(Specifications subject to specific customer requirements and lot COA)
6. Production Process: Precision from Resin to Powder
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Raw Material Sourcing & QC: Ethically harvested Boswellia resin undergoes strict identity and purity checks (TLC, Organoleptic).
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Primary Extraction: Estrazione di CO2 supercritica or Food-Grade Ethanol Extraction yields a crude oleoresin rich in Boswellic Acids.
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Purificazione: Advanced techniques like Macroporous Resin Chromatography O Counter-Current Chromatography isolate and concentrate Boswellic Acids (AKBA/KBA).
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High-Resolution Separation: Preparative HPLC/UPLC achieves ultra-high purity (>95% AKBA if required).
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Concentration & Solvent Removal: Low-temperature vacuum evaporation ensures thermal stability.
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Standardizzazione: Precise blending to achieve specified Boswellic Acid content (e.g., 65% AKBA).
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Asciugatura: Essiccazione a spruzzo O Lyophilization (Freeze-Drying) produces a stable powder.
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Final QC & Release: Comprehensive testing against specifications (HPLC/UPLC for potency, ICP-MS for metals, GC-MS/MS for pesticides, Microbiological assays). Batch traceability guaranteed.
7. Scenari applicativi
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Nutraceutici: Joint health supplements, immune support formulas, antioxidant blends.
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Cosmeceutici: Anti-aging serums, soothing creams, acne treatments, scalp health products.
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Alimenti e bevande funzionali: Fortified drinks, wellness bars, capsules.
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Intermedi farmaceutici: Research into novel anti-inflammatory drugs.
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Veterinary Supplements: Supporting joint health in companion animals.
8. Robust Quality Control
Zhonghong’s ISO 9001 & GMP-aligned QC system guarantees Frankincense Extract of exceptional quality and safety. Identità is confirmed via TLC, FTIR, and HPLC fingerprinting against authenticated reference standards. Potenza is rigorously quantified using Validated UPLC-DAD/MS Methods, precisely measuring AKBA, KBA, and total Boswellic Acids. Purezza is safeguarded through state-of-the-art contaminant testing: ICP-MS detects heavy metals (As, Pb, Cd, Hg) at ppb levels; GC-MS/MS screens for 200+ pesticide residues to EU MRLs; Validated Microbiological Methods (USP/EP) ensure safety from pathogens and spoilage organisms. Solventi residui are monitored per ICH Q3C using Headspace GC-MS. Physical Parameters (Loss on Drying, Ash, Particle Size) are strictly controlled. Stability studies (ICH guidelines) under accelerated and long-term conditions validate shelf life. Every batch undergoes >50 critical checks, with full traceability from raw resin to finished extract. Our superconducting NMR provides definitive structural confirmation for novel compounds and purity verification beyond standard methods.
9. Packaging & Logistics
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Primary Packaging: Food-grade polyethylene bags with double HDPE liners; vacuum-sealed or nitrogen-flushed for oxidation-sensitive grades. Tamper-evident seals.
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Imballaggio secondario: Sturdy, sealed fiberboard drums (25kg) or cartons (1kg, 5kg).
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Labeling: Compliant with destination regulations. Includes product name, batch number, manufacturing/expiry date, specifications (e.g., “65% AKBA”), net weight, GMO status, allergen statement, Zhonghong contact.
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Magazzinaggio: Cool (<25°C), dry conditions, away from light.
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Logistica: Efficient global shipping via air freight (DHL/FedEx/TNT) or sea freight. Expertise in customs documentation (Certificate of Origin, Health Certificate, COA, MSDS). Cold chain available.
10. Health Mechanisms, Applications & Research Frontiers
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Mechanism: Boswellic Acids, especially AKBA, potently inhibit 5-lipoxygenase (5-LOX), reducing leukotriene synthesis. They modulate Segnalazione NF-κB, downregulating pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) and enzymes (MMPs). Antioxidant effects combat ROS.
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Established Applications: Management of osteoarthritis, rheumatoid arthritis, IBD (Crohn’s, ulcerative colitis), asthma, and skin inflammation (psoriasis, eczema).
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Innovation: Zhonghong pioneers enhanced-bioavailability forms (phospholipid complexes, nanoparticles) and novel purification techniques yielding >95% AKBA fractions.
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Frontiere della ricerca: Investigating efficacy in oncology (anti-proliferative/anti-angiogenic effects), neurology (neuroprotection in models of Alzheimer’s, multiple sclerosis), metabolic health, and novel topical delivery systems. Key challenges include optimizing oral bioavailability and conducting large-scale, long-term clinical trials for newer indications.
11. Frequently Asked Questions (FAQ)
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Q: What’s your MOQ (Minimum Order Quantity)?
A: For standard grades, MOQ is typically 1kg. Larger bulk orders attract significant discounts. -
Q: Can you provide customized Frankincense Extract?
A: Absolutely. We specialize in customized herbal extract solutions – different AKBA/KBA ratios, specific particle sizes, enhanced bioavailability formats, or unique blends. -
Q: Do you offer free samples?
*A: Yes! Qualified B2B customers can request free sample herbal extract (typically 20-50g) for R&D and evaluation. Contact our sales team.* -
Q: What is the lead time?
*A: Standard grades: 7-15 days after order confirmation. Customized or large bulk orders: 3-6 weeks. Urgent requests accommodated.* -
Q: What certifications do you hold?
*A: ISO 9001, ISO 22000, GMP for food/cosmetic ingredients, Halal, Kosher (upon request), comprehensive product-specific COAs.* -
Q: How do you ensure sustainability?
A: We source resin through ethical partnerships supporting sustainable harvesting practices and local communities. -
Q: What payment terms do you accept?
A: T/T (Telegraphic Transfer), LC (Letter of Credit). Terms negotiable for established partners.
12. Where to Buy & Request Samples
Ready to source premium Frankincense Extract massa quantities or discuss customized solutions? As a leading factory E fornitore, Shaanxi Zhonghong offers competitive prices and exceptional quality.
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Request Your Free Sample: Evaluate our superior Frankincense Extract firsthand. Contact us today!
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Get a Quote: Inquire about all'ingrosso, bulk, or OEM pricing.
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Contact Us:
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E-mail: sales@aiherba.com | liaodaohai@gmail.com
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Sito web: www.aiherba.com
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13. Conclusion
Frankincense Extract, standardized to potent Boswellic Acids like AKBA, offers significant health-supporting properties, particularly for inflammatory balance and joint wellness. Choosing the right manufacturer is paramount. Shaanxi Zhonghong Investment Technology Co., Ltd., leverages 28 years of expertise, cutting-edge Supercritical CO2 E Chromatographic Purification technology, and an unwavering commitment to quality (evidenced by HPLC, NMR, ICP-MS testing) to deliver superior-grade Frankincense Extract. Our global reach, customized extract capabilities, and commitment to providing campioni gratuiti make us the ideal partner for nutraceutical, cosmetic, and pharmaceutical industries seeking reliable massa or specialized ingredients. Contact Zhonghong today to enhance your product line with the power of premium Frankincense.
14. Riferimenti
(Note: These represent the type of sources used. Specific product claims should be supported by relevant, current studies.)
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Ammon, H.P.T. (2010). Modulation of the immune system by Boswellia serrata extracts and boswellic acids. Fitomedicina.
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Siddiqui, M.Z. (2011). Boswellia serrata, a potential antiinflammatory agent: An overview. Indian Journal of Pharmaceutical Sciences.
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Abdel-Tawab, M., Werz, O., & Schubert-Zsilavecz, M. (2011). Boswellia serrata: An overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clinical Pharmacokinetics.
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ICH Q2(R1): Validation of Analytical Procedures: Text and Methodology.
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European Pharmacopoeia (Ph. Eur.) Monographs on Herbal Extracts.
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United States Pharmacopeia (USP) General Chapters: <561> Articles of Botanical Origin, <2023> Elemental Contaminants in Dietary Supplements, <61> Microbiological Examination.
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WHO guidelines on assessing quality of herbal medicines.
Recensioni
Ancora non ci sono recensioni.