Adenine

Adenine: Premium Manufacturer & Global Supplier for Pharmaceutical and Nutraceutical Applications | Aiherba

Source high-purity Adenine from Zhonghong, a leading manufacturer E fornitore all'ingrosso. Essential nucleic acid base for pharmaceuticals and supplements. Request a free sample and get a competitive price citazione.

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1. What is Adenine?

Adenine is a fundamental purine derivative, one of the four core nucleobases that form the building blocks of DNA and RNA. It is a crucial component of adenosine triphosphate (ATP), the primary energy currency of the cell, and various cofactors like NAD and FAD. Beyond its biological role, adenine is a key starting material and intermediate in the synthesis of numerous antiviral and anticancer drugs. For B2B clients in the pharmaceutical, nutraceutical, and research sectors, a reliable Adenine manufacturer is essential for sourcing a high-purity, compliant ingredient that meets strict quality standards for critical applications.

2. Source, Chemical Properties, and Identifiers

• Product Source: Primarily produced through chemical synthesis from simpler precursors like formamide or aminoimidazole carbonitrile (AICN) under controlled industrial conditions. This ensures high purity, consistency, and scalability.

• Chemical Classification: Purine base.

• Numero CAS: 73-24-5

• Formula molecolare (MF): C5H5N5

• Peso molecolare (MW): 135.13 g/mol

• EINECS: 200-796-1

3. What Defines the Best Adenine? A B2B Buyer’s Guide

Per internazionale pharmaceutical companies, supplement esportatori, and research institutions, the “best” Adenine is defined by its ultra-high purity, low impurity profile (especially for related substances like other nucleobases), and comprehensive documentation supporting its intended use (e.g., DMF, CEP).

• Ingrediente chiave ed efficacia: Premium Adenine is a synthetic compound of high purity (e.g., ≥99.0% or USP/EP grade). Its primary roles are structural and functional:

  • Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside analogue drugs (e.g., Acyclovir, Tenofovir) used to treat viral infections and cancers.

  • Cell Culture Media Component: Used in biopharmaceutical manufacturing as a key nutrient for cell growth and proliferation.

  • Research Reagent: Essential for molecular biology research, PCR, and genetic studies.

  • (Compliant for use as a pharmaceutical intermediate, in cell culture, and as a research chemical. Not typically sold as a direct dietary supplement ingredient.)

• Origine e qualità: Our Adenine is synthesized in cGMP-compliant facilities, ensuring a product free from biological contaminants and with a consistent, well-defined chemical profile.

• Utilizzo e dosaggio:

  • Utilizzo tipico: Incorporated as an active pharmaceutical ingredient (API) intermediate, a raw material in cell culture media, and a reagent in diagnostic kits and research laboratories.

  • Recommended Dosage: There is no standard dietary dosage. All usage is highly specific to the pharmaceutical synthesis protocol, cell culture formulation, or research application.

• Applicable Audience: Pharmaceutical synthesis departments, biopharmaceutical companies, research institutions, and diagnostic kit manufacturers.

• Notes & Side Effects:

  • Precauzioni: FOR INDUSTRIAL AND RESEARCH USE ONLY. Not intended for direct human consumption as a dietary supplement. Handle with appropriate personal protective equipment (PPE) in a laboratory setting.

  • Side Effects: Not applicable for this B2B context. As a pharmaceutical intermediate, its safety profile is managed within the drug development process.

4. Why Partner with Zhonghong (Aiherba) as Your Adenine Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (Global Marketing: Aiherba) is a certified high-tech enterprise and a trusted esportatore specializing in the synthesis and purification of high-value chemical and biochemical compounds for the global B2B mercato.

• Eccellenza scientifica: Our joint laboratories with 5 leading universities and portfolio of 20+ patents allow us to optimize synthetic pathways for high yield, purity, and minimal environmental impact.

• Unmatched Quality Control: Our investment in advanced equipment like HPLC and Superconducting NMR ensures our purity standards meet or exceed USP, EP, and JP monograph requirements, which is critical for pharmaceutical applications.

• Global B2B Network: With 28 years of experience in fine chemicals, we supply customized ingredients and all'ingrosso quantities to multinational pharmaceutical corporations, all'ingrosso distributors, and premier research institutions across 80+ countries.

• Regulatory Support: We provide comprehensive documentation packages, including C of A, MSDS, and can support regulatory filings, making us a strategic partner for the pharmaceutical industry.

5. Detailed Product Specifications (COA)

Every batch is accompanied by a comprehensive Certificate of Analysis (COA) that confirms compliance with stringent pharmacological standards.

6. Production Process & Quality Control

Our production of Adenine involves multi-step chemical synthesis from validated starting materials. The process typically begins with precursors like formamide or AICN, undergoing a series of controlled reactions (e.g., cyclization, purification) to build the purine ring structure. The crude product is then purified through techniques such as recrystallization from a suitable solvent or chromatography to achieve the desired pharmaceutical-grade purity. The final product is dried and milled to a consistent particle size if required.

Nostro Controllo di qualità is exceptionally rigorous and designed for pharmaceutical intermediates. It starts with qualifying all raw materials. In-process controls (IPC) are implemented at critical steps to monitor reaction completion and impurity profiles. The final product undergoes exhaustive testing. Cromatografia liquida ad alte prestazioni (HPLC) with UV detection is the primary method for quantifying the Adenine content and profiling related substances and impurities. ICP-MS is used for sensitive heavy metal detection. Karl Fischer titration precisely measures water content. Additionally, we perform microbiological testing to ensure bioburden limits are met. This multi-tiered QC protocol, conducted in our state-of-the-art labs, guarantees a product that is consistent, pure, and suitable for its demanding applications.

7. Scenari applicativi

Adenine is a critical ingredient for advanced industries:

• Prodotti farmaceutici: Primarily used as a key intermediate in the synthesis of a wide range of antiviral and anticancer nucleoside analogue drugs.

• Biopharmaceuticals: An essential component of defined cell culture media used in the production of monoclonal antibodies, vaccines, and other biologics.

• Molecular Biology & Diagnostics: Used as a raw material in PCR kits, nucleotide synthesis, and various research reagents.

• Chemical Research: Serves as a building block for novel chemical entities and materials science research.

8. Technical Role, Research, and Innovation

Adenine’s role is structural and functional, serving as a core scaffold in nucleic acids and critical biomolecules. The main research frontier involves developing more efficient and greener synthetic routes for its production and creating novel derivatives with enhanced biological activities. The key challenge for manufacturers is achieving and consistently maintaining ultra-high purity with minimal isomeric and other purine impurities, which is crucial for pharmaceutical efficacy and safety. At Zhonghong, our innovazione lies in our patented, optimized synthesis pathways that maximize yield and purity while reducing environmental impact, providing our B2B partners with a reliable and high-quality building block for their most important products.

9. FAQ – Frequently Asked Questions

Q: What is the Minimum Order Quantity (MOQ) for pharmaceutical grade?
A: MOQs vary based on the specific grade and packaging. We cater to both large-scale all'ingrosso orders for production and smaller R&D quantities. Contact us for details.

Q: Can you provide Adenine that complies with USP/EP/JP monographs?
A: Yes, we can supply Adenine that meets the specifications of various international pharmacopoeias. Please specify your required standard when inquiring.

Q: Do you offer custom synthesis for Adenine derivatives?
A: Yes, we specialize in customized herbal extract and chemical solutions. Our R&D team can collaborate on the synthesis of specific purine derivatives. Inquire for feasibility.

Q: Do you offer samples for our quality testing and R&D?
A: Absolutely. We provide campione gratuito materials to qualified businesses and research institutions for evaluation and testing purposes.

Q: What documentation do you provide for pharmaceutical customers?
A: We provide a comprehensive suite including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and can provide supporting data for Drug Master Files (DMF) as required.

10. Where to Buy and Request Free Samples

As a leading manufacturer E global supplier of fine chemicals and pharmaceutical intermediates, we are your trusted partner for sourcing high-purity Adenine.

Contact us today to discuss your procurement needs, request a free sample for your QA/QC, and get a competitive wholesale price.

• E-mail: sales@aiherba.com / liaodaohai@gmail.com

• Sito web: www.aiherba.com

11. Conclusion

Per B2B clients in the pharmaceutical and life science industries, Adenine is a fundamental, non-negotiable building block. Choosing a supplier with robust synthetic capabilities, uncompromising quality control aligned with pharmacopoeial standards, and proven internazionale regulatory support is paramount. Zhonghong (Aiherba) provides not just a chemical, but a reliable partnership, offering a premium, thoroughly documented product that integrates seamlessly into your critical workflows, backed by decades of experience in chemical manufacturing.

12. Riferimenti

• USP/EP/JP Monographs for Adenine.

• Journal of Medicinal Chemistry: Studies on the synthesis and application of purine derivatives in drug discovery.

• Organic Process Research & Development: Publications on the industrial synthesis and optimization of nucleobases.

• ICH Guidelines (Q3A, Q7) for impurities in new drug substances and Good Manufacturing Practice.