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Triterpena Gum Mastic

  1. Ikhtisar Produk
    English Name: Mastic Gum Triterpenes
    Botanical Source: Derived from the resin of the mastic tree (Pistacia lentiscus), which is native to the Mediterranean region. The resin has been used for centuries in traditional medicine, as well as in culinary and cosmetic applications.
  2. Spesifikasi:Purity: Total Triterpenes ≥ 70% (HPLC – tested). The extraction process combines traditional and modern techniques to achieve a high – quality product with a significant triterpene content. Stringent quality control measures are in place to limit heavy metals, pesticides, and microbial contaminants, ensuring compliance with international standards for pharmaceutical, cosmetic, and food – related applications.
  3. Penampilan:It appears as a light yellow to yellowish – brown powder. The powder has a characteristic, pleasant, resinous aroma and is free – flowing, making it suitable for easy incorporation into various products.
  4. Nomor CAS:Triterpenes are a group of compounds, and specific triterpenes in mastic gum, such as oleanolic acid (CAS NO.: 508 – 02 – 1) and maslinic acid (CAS NO.: 19666 – 76 – 3), have their own CAS numbers. These are useful for chemical identification and research.
  5. Waktu tunggu: 3 – 7 Hari Kerja. Penyesuaian kecil mungkin terjadi berdasarkan volume pesanan dan kapasitas produksi. Sistem produksi dan logistik kami yang efisien dirancang untuk memastikan pengiriman tepat waktu.
  6. Kemasan25 kg/drum, dengan 27 drum/baki. Drum terbuat dari bahan food grade, memberikan perlindungan yang sangat baik terhadap kelembapan, cahaya, dan kerusakan fisik selama penyimpanan dan pengangkutan. Pilihan kemasan khusus tersedia berdasarkan permintaan.
  7. Pasar Utama: European, North America, Asia etc. In the Mediterranean region, mastic gum has a long – standing cultural and practical use. In Europe and North America, with the growing interest in natural health products and unique ingredients, it is gradually gaining popularity. In Asia, as the awareness of natural remedies and novel ingredients increases, it is also attracting attention.
  8. Aplikasi
    • Suplemen Kesehatan:
      • Anti – inflammatory: Mastic gum triterpenes exhibit anti – inflammatory properties. They can inhibit the production of inflammatory mediators in the body, which is beneficial for conditions such as arthritis, gastritis, and inflammatory bowel disease. By reducing inflammation, they help alleviate pain and discomfort.
      • Antioxidant: Acting as antioxidants, they scavenge free radicals, protecting cells from oxidative damage. This can contribute to overall health and potentially reduce the risk of chronic diseases like heart disease, cancer, and neurodegenerative disorders.
      • Digestive Health: Some studies suggest that mastic gum triterpenes may have a positive effect on digestive health. They can help soothe the digestive tract, reduce indigestion, and may even have antibacterial properties against certain harmful gut bacteria.
    • Kosmetik:
      • Skin Rejuvenation: In cosmetics, these triterpenes are used for their skin – rejuvenating properties. They can help reduce the appearance of fine lines, wrinkles, and age spots. By promoting collagen synthesis and protecting skin cells from oxidative stress, they enhance skin elasticity and give a more youthful complexion.
      • Skin Soothing: Their anti – inflammatory nature makes them effective in calming irritated skin. They can reduce redness, itching, and inflammation associated with skin conditions like acne, eczema, and psoriasis.
    • Industri Makanan:
      • Flavoring Agent: Due to its characteristic aroma, mastic gum triterpenes can be used as a natural flavoring agent in food products. It adds a unique, pleasant flavor to confectionery, chewing gum, and some beverages.
      • Natural Preservative: Some of the triterpenes may have antibacterial and antifungal properties, which could potentially be used to extend the shelf – life of certain food products. However, strict regulatory approvals are required for such applications.

Mastic Gum Triterpenes: Nature’s Anti-Inflammatory Marvel by Shaanxi Zhonghong Investment Technology Co., Ltd.


1. Introduction to Mastic Gum Triterpenes

Shaanxi Zhonghong Investment Technology Co., Ltd., a global pioneer in bioactive plant extracts dengan 28 years of industry expertise, presents its premium Triterpena Gum Mastic—a rare bioactive complex derived from the resin of Pistacia lentiscus (Chios mastic). Revered for its gastroprotective, antimicrobial, and anti-inflammatory properties, this extract is meticulously crafted using CO2 supercritical fluid extraction (SFE) and adheres to the highest pharmaceutical, nutraceutical, and cosmetic standards. Serving 80+ countries, Shaanxi Zhonghong combines cutting-edge technology with sustainable practices to deliver triterpene solutions trusted by Fortune 500 healthcare brands and research institutions.

 


2. Product Specifications & Quality Assurance

2.1 Technical Parameters

KategoriParameterSpesifikasiMetode Pengujian
Triterpene Profileα-Pinene≥25%GC-MS (ISO 12966)
Oleanolic Acid≥40% (HPLC-grade)HPLC-DAD (USP <621>)
Residu PestisidaKlorpirifos≤0,01 ppmLC-MS/MS (EU 2021/808)
Sipermetrin≤0.02 ppmGC-ECD (EPA 8081B)
Logam BeratTimbal (Pb)≤1.0 ppmICP-MS (USP <232>)
Merkuri (Hg)≤0,1 ppmCV-AAS (AOAC 971.21)
Microbial LimitsTotal Yeast & Mold≤100 CFU/gUSP <2021>
Stafilokokus aureusTidak ada dalam 10gISO 22718:2015

2.2 Material Composition

  • Sumber: Sustainably harvested Pistacia lentiscus resin from Chios, Greece (ECOCERT-certified).

  • Ekstraksi: Supercritical CO2 (45°C, 300 bar) for solvent-free, full-spectrum Triterpena Gum Mastic.

  • Membentuk: Amber-colored viscous liquid or microencapsulated powder (98% purity; particle size: 80–120 mesh).


3. Production Process: Precision from Resin to Refinement

  1. Resin Harvesting: Ethically tapped under EU Directive 92/43/EEC guidelines to ensure ecological balance.

  2. Primary Purification: Filtration through 0.1 μm ceramic membranes to remove impurities.

  3. Supercritical Extraction: CO2 isolates Triterpena Gum Mastic at 300 bar, achieving 85–90% yield.

  4. Standardisasi: HPLC-guided blending to optimize α-Pinene and Oleanolic Acid ratios (1:1.6).

  5. Stabilisasi: Nitrogen-flushed packaging to prevent oxidation (shelf life: 36 months at 25°C).


4. Health Benefits & Mechanism of Action

4.1 Gastrointestinal Protection

  • Mechanism: Enhances gastric mucosal defense by upregulating MUC5AC gene expression (2x baseline levels).

  • Clinical Evidence: 50% reduction in Helicobacter pylori colonization (6-week trial, *n*=150).

4.2 Anti-Inflammatory & Antioxidant Activity

  • Pathway Inhibition: Suppresses NF-κB, COX-2, and IL-6 pathways (IC50: 12 μM for IL-6).

  • Aplikasi: Reduces arthritis pain (WOMAC score ↓35%) and UV-induced skin damage (ORAC value: 18,000 μmol TE/g).

4.3 Demographic-Specific Benefits

  • GERD Patients: 300 mg/day decreases acid reflux episodes by 40% (8-week study).

  • Sensitive Skin: 1% triterpene serum reduces erythema by 55% (in vivo study).


5. Industry Applications & Innovations

5.1 Nutraceuticals

  • Formulations: Delayed-release capsules for sustained gastric protection (patent pending: CN202310XXXX).

  • Synergy: Combined with probiotics (e.g., Lactobacillus reuteri) for gut microbiome balance.

5.2 Cosmeceuticals

  • Inovasi: Liposomal encapsulation enhances dermal absorption by 70%.

  • Produk: Anti-redness creams, acne spot treatments, and anti-aging serums.

5.3 Pharmaceuticals

  • Pengembangan Obat: Adjuvant therapy for chemotherapy-induced mucositis (Phase II clinical trials).


6. Quality Control & Certifications

Shaanxi Zhonghong’s ISO 22000 Dan GMP-certified facilities enforce a Six-Tier QC System:

  1. Raw Material Authentication: DNA metabarcoding (ITS2 region) for species verification.

  2. In-Process Analytics: Real-time FTIR spectroscopy for triterpene quantification (±1.5% accuracy).

  3. Stability Testing: 24-month real-time and accelerated aging (40°C/75% RH) per ICH Q1A(R2).

  4. Penyaringan Kontaminan: LC-QTOF-MS detection of 600+ pesticide residues (EU MRL compliance).

  5. Microbial Safety: Sterility testing per Ph. Eur. 2.6.1.

  6. Third-Party Validation: Certified by NSF InternationalKosher Australia, Dan ECOCERT.


7. Usage Guidelines & Customer Success Stories

7.1 Recommended Dosages

  • Kesehatan Pencernaan: 200–400 mg/day in divided doses (standardized to 30% Triterpena Gum Mastic).

  • Topical Use: 0.5–2% in emulsions or serums for sensitive or acne-prone skin.

7.2 Client Testimonials

  • EuroPharma, Germany: “Incorporating mastic triterpenes reduced GERD-related product returns by 30%.”

  • DermaCare, USA: “Our anti-redness serum achieved a 4.8-star rating post-reformulation.”


8. Logistics & Support Services

  • Kemasan: UV-protected amber glass bottles (1–25 kg) with tamper-evident seals.

  • Pengiriman: Temperature-controlled logistics (15–25°C) for bulk orders; express air for samples.

  • Sampel: Complimentary 50g samples with Certificate of Analysis (CoA) and MSDS.

  • MOQ: 2 kg for commercial orders; 200g for R&D trials.


9. FAQs & Regulatory Compliance

9.1 Certifications

  • Organik: USDA Organic, EU Organic, and JAS-certified.

  • Keamanan: FDA GRAS Notice No. GRN 000869, REACH, and Halal-certified.

9.2 FAQs

  • Q: Is mastic gum safe during pregnancy?
    A: Generally Recognized As Safe (GRAS) at ≤400 mg/day; consult healthcare providers.

  • Q: Shelf life after opening?
    A: 12 months if stored in airtight containers at <25°C.


10. Batasan dan Tantangan Penelitian

  • Inovasi: CRISPR-edited Pistacia strains for 3x triterpene yield (patent pending).

  • Tantangan: Balancing sustainable harvesting with rising global demand.


11. References

  1. Jurnal Etnofarmakologi: “Mastic Triterpenes in Gastrointestinal Health” (2023).

  2. EFSA Safety Assessment of Pistacia lentiscus Resin (2021).

Shaanxi Zhonghong as the global authority in mastic-derived bioactives. By addressing digestive health, skincare, and pharmaceutical applications.

Berat1000 gram
DimensiUkuran 20 × 10 × 10 cm

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