Ganoderma Lucidum Polisakarida
Ganoderma Lucidum Polysaccharide - Gambar 2
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Ganoderma lucidum polisakarida

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. Nama Inggris: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Spesifikasi
    • Polysaccharide Content: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Kelarutan: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Kelembaban: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Logam Berat: ≤ 10 ppm (benar-benar aman untuk penggunaan oral—memenuhi standar makanan/kesehatan yang ketat)
    • Kemurnian: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Penampilan: Light yellow to off-white powder with a mild, earthy mushroom smell—tentu saja no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. NOMOR CAS.: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Waktu tunggu: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Kemasan: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Pasar Utama: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Skenario Aplikasi

Fitur Utama

  • “Kekuatan Super” Reishi: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Campuran Serbaguna: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Alami & Bersih: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Penyimpanan Stabil: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Aplikasi Industri

  1. Suplemen Makanan
    • Kapsul/Bubuk Reishi: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • Formula Pendukung Kekebalan Tubuh: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Makanan & Minuman Fungsional
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Produk Kesehatan Tradisional
    • TCM Formulations: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Specialty Nutrition
    • Senior Wellness: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Produk Vegan/Berbasis Tanaman: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness
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Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. Apa itu Polisakarida Ganoderma Lucidum?

Polisakarida Ganoderma lucidum (GLP) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Jamur Reishi). Secara struktural, mereka terdiri dari Tulang punggung β-(1→3)-D-glukan dengan Cabang β-(1→6)-D-glukosil, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1.000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.

2. Pasokan, Sifat Kimia & Spesifikasi Teknis

Sumber dan Ekstraksi Botani

  • Main Supply: Fruiting our bodies of Ganoderma lucidum atau G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Strategi Ekstraksi:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ekstraksi berbantuan ultrasonik (40 kHz) → pemurnian resin makropori (AB-8) → liofilisasi

Chemical Identification

Milik Bernilai
Nomor CAS. Not assigned (advanced combination)
Rumus Molekul (C₆H₁₀O₅)ₙ
Berat Molekul 10–1.000 kDa
EINECS Not relevant
Penampilan Mild brown hygroscopic powder
Kelarutan Larut dalam air; tidak larut dalam etanol
Bioaktivitas Utama ikatan glikosidik β-(1→3)/(1→6) ≥85%

3. Manfaat Kesehatan, Dosis Optimal & Keamanan

Hasil Terapi yang Tervalidasi

  • Imunomodulasi:

    • ↑ Fagositosis makrofag oleh 300% dan ↑ Sitotoksisitas sel NK by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • Menginduksi apoptosis pada sel HepG2 (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Pengaturan Metabolisme:

    • ↓ Glukosa darah puasa by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoproteksi:

    • Mengurangi ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Saran Dosis

  • Kesehatan Umum: 100–300 mg/hari (20–30% GLPs)

  • Penggunaan Terapi:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Ambang Keamanan: ≤3,000 mg/day (no noticed toxicity)9.

Vital Precautions

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Prosedur bedah: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Interaksi Obat: Might potentiate immunosuppressants (e.g., cyclosporine).

4. Perkenalan Perusahaan: Shaanxi Zhonghong Biotechnology Co., Ltd.

A Pelopor selama 28 tahun dalam manufaktur polisakarida bioaktif, Shaanxi Zhonghong terintegrasi teknologi ekstraksi milik sendiri with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Kemampuan Inti:

  • Ekstraksi yang Dilindungi Paten: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Ketelitian Analisis: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain >kemurnian 99.5% (melebihi monograf USP/EP).

  • Kepatuhan Internasional: Sertifikasi ISO 9001, FDA-GMP, EFSA, JECFA.

  • Menyediakan Penguasaan Rantai: Logistik rantai dingin di 80+ negara.

5. Product Specs: Pharmaceutical-Grade GLP QC

Contaminant Testing Requirements

Kelas Parameter Membatasi Periksa Teknik
Pestisida Klorpirifos ≤0,01 ppm GC-MS/MS (UE 396/2005)
Glifosat ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Logam Berat Timbal (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsenik (As) ≤0,5 ppm AAS (EP 2.4.27)
Mikrobiologi Seluruh Piring Tergantung ≤1.000 CFU/gram USP <61>
Bakteri E. coli Absen ISO 16654
Salmonella spp. Absen FDA BAM Bab 5

6. Alur Kerja Manufaktur yang Unggul

  1. Sumber: Alami G. lucidum fruiting our bodies (OOP-certified).

  2. Ekstraksi: Maserasi dinamis (95°C, pH 6,8, 3 jam) → ultrafiltrasi (100 kDa MWCO).

  3. Deproteinisasi: Reagen Sevag (kloroform:butanol 4:1).

  4. Pemurnian: Kromatografi DEAE-Sepharose FF → liofilisasi.

  5. Standardisasi: Phenol-sulfuric acid assay to 40% GLP content material.

7. Tujuan di Seluruh Industri

  • Nutrisi: Kapsul penambah kekebalan (sinergi GLP + β-glukan).

  • Obat resep: Adjuvan kemoterapi (mengurangi nefrotoksisitas cisplatin).

  • Kosmetik: Serum anti-penuaan (↑ sintesis kolagen oleh 200%).

  • Makanan Berguna: Glycemic management drinks (GLP + berberine).

8. Manajemen Kualitas Tinggi: Protokol Jaminan 360°

GLP batches bear verifikasi empat fase:

  1. Afirmasi Identifikasi: Pencocokan spektral FT-IR (3.400 cm⁻¹ OH; 1.070 cm⁻¹ COC).

  2. Kuantifikasi Kemurnian: HPSEC-ELSD (ICH Q2(R1)-tervalidasi; LOD: 0,05%).

  3. Pengujian Bioaktivitas:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • Penghambatan α-Glukosidase: IC₅₀ ≤ 2 mg/mL

  4. Stabilitas: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).

9. Analisis Batasan & Tantangan

  • Wawasan Mekanistik:

    • Intestine microbiota modulation (↑ Bakteri Bifido ↑ SCFA manufacturing).

    • Aktivasi jalur STING untuk kekebalan antitumor.

  • Terjemahan Medis:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Batasan Teknis:

    • Bioavailabilitas Oral: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Heterogenitas StrukturalOptimasi reproduktifitas antar-batch.

  • Keberlanjutan:

    • Mycelial fermentation to preserve wild Ganoderma populasi.

10. FAQ: Solusi Terampil

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

T: Waktu konsumsi yang optimal?
A: Morning on empty abdomen (enhances macrophage uptake).

The place to Purchase Pharmaceutical-Grade GLPs

🔬 Pesanan Langsung dari Shaanxi Zhonghong:

Kesimpulan

Polisakarida Ganoderma lucidum mendefinisikan ulang imunonutrisi presisi—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!

Referensi:

  1. Jurnal Etnofarmakologi (2019). GLP mechanisms in most cancers apoptosis9.

  2. Polimer Karbohidrat (2020). Karakterisasi struktural GLP imunomodulatori6.

  3. Kimia Makanan (2021). Optimasi ekstraksi ultrasonik-gelombang mikro3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Batasan dalam Imunologi (2024). Aktivasi jalur STING oleh GLP.

1 ulasan untuk Ganoderma lucidum polysaccharide

  1. Avatar Dari James Oli***
    Dinilai 4 dari 5

    James Oli*** –

    Sebagai merek produk perawatan kesehatan, solusi ODM aiherba.com memberi kami ketenangan pikiran. Mereka menyediakan berkas ketertelusuran bahan baku yang lengkap. Misalnya, batch terbaru ekstrak triterpenoid Ganoderma lucidum dapat dilacak dari penanaman hingga proses ekstraksi basis organik di Yunnan. Mereka bahkan dapat menyediakan laporan uji tanah dasar, yang menjadi daya saing inti kami selama negosiasi.

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