Hydroxypropyl Tetrahydropyrantriol
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Hydroxypropyl Tetrahydropyrantriol

Hydroxypropyl Tetrahydropyrantriol (Pro-Xylane™): The Ultimate Guide by Zhonghong Tech

1.English Name: Hydroxypropyl Tetrahydropyrantriol

  1. Specification
    • Purity: ≥ 98% (HPLC)
    • Solubility: Highly soluble in water (≥ 50 g/100 mL at 25°C), soluble in glycerin and propylene glycol
    • pH Value: 5.0 – 7.0 (5% aqueous solution)
    • Loss on Drying: ≤ 1.0%
    • Heavy Metals: ≤ 10 ppm
  1. Appearance: Colorless to pale yellow transparent liquid, odorless, with no chocolate-related properties
  1. CAS NO.: 439685-79-7
  1. Lead time: 3 – 7 Working Days
  1. Package: 1 kg/bottle, 5 kg/barrel, 25 kg/drum (plastic or glass containers)
  1. Main Market: Europe, North America, Asia, etc.
  1. Application Scenarios

Key Properties

  • Collagen Stimulation: Promotes the synthesis of type I, III, and IV collagen, enhancing skin elasticity and firmness
  • Skin Barrier Enhancement: Strengthens the extracellular matrix, improving the skin’s protective barrier function
  • Anti-aging: Reduces the appearance of fine lines and wrinkles by supporting skin structure
  • Deep Penetration: Easily penetrates the epidermis to reach the dermis, exerting long-term effects
  • Compatibility: Stable in various formulations, compatible with most cosmetic ingredients (acids, alcohols, etc.)

Application Scenarios

  1. Anti-aging Skincare
    • Facial Serums: Added at 2 – 5% concentration to target fine lines and improve skin firmness
    • Creams and Lotions: Used in day and night creams to support collagen production
    • Eye Care Products: Included in eye creams to reduce crow’s feet and under-eye wrinkles
  1. Repair and Recovery Formulations
    • Post-sun Products: Helps repair UV-damaged skin and restore barrier function
    • Post-treatment Care: Used in products after cosmetic procedures (peels, lasers) to aid skin recovery
  1. Body Care
    • Firming Lotions: Added to body creams to improve skin elasticity on areas like thighs and abdomen
    • Neck and Decolletage Products: Targets signs of aging in delicate areas
  1. Sensitive Skin Products
    • Formulated in gentle skincare lines to strengthen the skin barrier without irritation
  1. Men’s Skincare
    • Included in anti-aging products for men, addressing thicker skin texture and aging concerns

Detection Methods

  • HPLC: Column C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Acetonitrile – water (10:90, v/v), Flow Rate: 1.0 mL/min, Detection Wavelength: 210 nm
  • NMR Spectroscopy: ¹H NMR used to confirm chemical structure and purity
  • Refractive Index: Measured at 20°C, typical range 1.460 – 1.470

Advantages

  • Proven Efficacy: Backed by clinical studies demonstrating collagen-boosting and anti-aging effects
  • Gentle on Skin: Non-irritating, suitable for all skin types including sensitive skin
  • Stable Formulation: Maintains activity under normal storage and processing conditions (temperature ≤ 50°C)
  • Multi-functional: Combines barrier repair, collagen stimulation, and anti-aging benefits in one ingredient
Categories: ,

Hydroxypropyl Tetrahydropyrantriol (Pro-Xylane™) | Bulk Supply & OEM Factory | AIHerba®
High-Purity Cosmetic Active for Anti-Aging, Moisturizing, and Skin Barrier Repair

1. Product Overview

Hydroxypropyl Tetrahydropyrantriol, also known as Pro-Xylane™, is a biomimetic sugar-derived molecule developed to enhance skin firmness, hydration, and elasticity. Derived from xylose (a natural plant sugar), this active ingredient supports the synthesis of glycosaminoglycans (GAGs) and helps rebuild the skin’s extracellular matrix, making it a premium anti-aging component in cosmetics and dermatological formulations.

AIHerba® (Shaanxi Zhonghong Investment Technology Co., Ltd.) supplies high-purity Hydroxypropyl Tetrahydropyrantriol for bulk purchase, OEM & ODM projects, backed by GMP-certified production and ISO quality systems.

2. Product Source & Production Process

Source: Derived from natural xylose extracted from beechwood or birchwood.
Production Technology:

  1. Xylose extraction →

  2. Hydroxypropylation reaction →

  3. Cyclization into tetrahydropyrantriol →

  4. Purification & concentration →

  5. Filtration, quality inspection & packaging

Extraction Techniques: Water–ethanol extraction, enzymatic bioconversion, and molecular purification ensure product stability, purity, and bioavailability.

3. Key Benefits & Efficacy

Function Description
Anti-Aging & Firmness Stimulates GAG and collagen synthesis to restore dermal density.
Deep Hydration Enhances water retention and strengthens the skin’s moisture barrier.
Skin Barrier Repair Promotes regeneration of damaged tissue and supports matrix integrity.
Elasticity Improvement Improves mechanical resilience and smoothness of mature skin.
Compatibility Safe and synergistic with hyaluronic acid, niacinamide, peptides, and ceramides.

4. Health & Cosmetic Benefits

  • Reduces visible wrinkles and fine lines

  • Supports dermal matrix reconstruction

  • Improves firmness and radiance

  • Restores youthful plumpness and hydration

  • Clinically tested for sensitive skin tolerance

5. Recommended Usage & Formulation Guide

Application Recommended Dosage Notes
Face cream / serum 1–5% For anti-aging and hydration
Eye cream 0.5–2% Reduces fine lines and puffiness
Body lotion 0.5–3% Improves elasticity and tone
Essence / ampoule 2–5% Boosts firmness and moisture
Anti-aging masks 1–3% Enhances GAG production

Formulation Tip:
Combine with Sodium Hyaluronate, Ceramide NP, or Niacinamide for synergistic moisturizing and barrier support effects.

Solubility: Water-soluble
Stability: Stable in pH 4–8; avoid strong oxidizers

6. Specifications & COA Summary

Parameter Specification Test Method
Appearance Clear to light-yellow viscous liquid Visual
Purity (HPLC) ≥ 99% HPLC
Odor Characteristic, mild Sensory
pH (1% solution) 4.5–6.5 pH Meter
Specific Gravity 1.15–1.25 Density Test
Solubility Water-soluble Visual

Pesticide Residue Analysis

Item Limit (mg/kg) Method
Organochlorine pesticides ≤0.1 GC-MS
Organophosphorus pesticides ≤0.1 GC-MS
Carbamates ≤0.05 LC-MS/MS
Pyrethroids ≤0.05 LC-MS/MS

Heavy Metal Analysis

Item Limit (ppm) Method
Lead (Pb) ≤1.0 ICP-MS
Arsenic (As) ≤1.0 ICP-MS
Cadmium (Cd) ≤0.5 ICP-MS
Mercury (Hg) ≤0.1 AAS

Microbiological Control

Item Specification Method
Total Plate Count ≤100 CFU/g GB 4789.2
Yeast & Mold ≤50 CFU/g GB 4789.15
E. coli Negative GB 4789.3
Salmonella Negative GB 4789.4
Staphylococcus aureus Negative GB 4789.10

7. Manufacturing Capability

  • GMP-certified and ISO9001 / ISO22000 / Halal / Kosher compliant

  • Over 28 years of R&D and production experience

  • Supercritical CO₂ and enzymatic synthesis ensure purity and eco-friendliness

  • In-house QC laboratory with HPLC, GC-MS, ICP-MS instruments

  • Customized OEM / ODM cosmetic ingredient solutions available

8. Packaging, Storage & Shelf Life

Item Details
Packaging 1 kg aluminum bottle, 25 kg HDPE drum
Storage Condition Keep in a cool, dry, and dark place, sealed tightly
Shelf Life 24 months unopened
Sample Policy Free samples (≤20 g) available for testing
MOQ 1 kg for trial orders
Lead Time 5–7 working days after payment
Shipping DHL, FedEx, air freight, or sea shipment with export documentation

9. Application Industries & Use Cases

Industry Applications
Cosmetics & Skincare Anti-aging creams, serums, firming masks, eye creams
Dermocosmetics Dermatologist formulations for skin elasticity and hydration
Functional Foods Possible topical supplement delivery systems (cosmetic-nutritional crossover)
Pharmaceutical Used in skin repair and anti-aging topical drugs

10. Safety & Precautions

  • For external use only

  • Avoid contact with eyes and mucous membranes

  • Store away from high heat and direct sunlight

  • Conduct a patch test before large-scale application

  • Complies with EU Cosmetic Regulation (EC) No 1223/2009

11. Certifications & Quality Assurance

  • GMP, ISO9001, ISO22000

  • Halal & Kosher Certified

  • COA, MSDS, and TDS available upon request

  • Third-party laboratory testing supported

12. Frequently Asked Questions (FAQ)

Q1: What’s the difference between Hydroxypropyl Tetrahydropyrantriol and Pro-Xylane™?
A1: Pro-Xylane™ is the trade name by L’Oréal; both refer to the same molecule, Hydroxypropyl Tetrahydropyrantriol.

Q2: Can it be used in natural or organic skincare formulations?
A2: Yes. It’s derived from natural xylose and compatible with natural formulations.

Q3: What’s the ideal pH range for formulation?
A3: pH 4.0–7.0 ensures maximum stability and activity.

Q4: Does AIHerba provide OEM/ODM support?
A4: Yes. AIHerba offers full formulation design, private labeling, and customized ingredient sourcing.

Q5: Is it safe for sensitive skin?
A5: Yes. Clinical studies demonstrate high tolerance even for delicate skin types.

13. References (Scientific Validation)

  1. L’Oréal Research Division, Hydroxypropyl Tetrahydropyrantriol: A New Active for Skin Matrix Reinforcement, 2006.

  2. PubMed ID: 17080976 – Glycosaminoglycan synthesis stimulation by xylopyranoside derivatives.

  3. NIH: Cosmetic Ingredient Safety Review – Hydroxypropyl Tetrahydropyrantriol

  4. FDA Cosmetic Ingredient Database (CIR Panel, 2023).

14. Contact & Factory Information

📍 Manufacturer: Shaanxi Zhonghong Investment Technology Co., Ltd. (AIHerba®)
🏭 Factory Location: Xi’an, Shaanxi, China
📧 Email: sales@aiherba.com | info@aiherba.com | liaodaohai@gmail.com
🌐 Website: www.aiherba.com

AIHerba® – Trusted China Natural Plant Extracts Supplier & OEM Factory
Providing GMP-certified, traceable, and high-performance cosmetic ingredients for global brands.

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