कार्यात्मक खाद्य पदार्थों, पेय पदार्थ जोड़ना, सौंदर्य प्रसाधन और व्यक्तिगत देखभाल, खाद्य योज्य, स्वास्थ्य उत्पाद, स्वास्थ्य सेवा और फार्मास्युटिकल सामग्री, प्राकृतिक पौधों के अर्क

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अंग्रेजी नाम: Citric Acid

विनिर्देश

- पवित्रता: ≥ 99.5% (एचपीएलसी)

- घुलनशीलता: अत्यंत soluble in water (133 g/100 mL at 20°C), soluble in ethanol (≥ 50 g/100 mL)

- Appearance – संबंधित: सुखाने पर हानि ≤ 0.5%, भारी धातुएँ ≤ 5 ppm, अवशिष्ट विलायक ≤ 0.2%

- गलन स्तर: 153°C

उपस्थिति

- Colorless स्पष्ट crystals or white crystalline powder, odorless, with एक शक्तिशाली, acidic शैली, not संबंधित to chocolate

CAS संख्या।：77 – 92 – 9

समय सीमा: 3 – 7 कार्य दिवस

पैकेट

- 25kg/drum (polyethylene bag inside cardboard drum), 1000kg/bag (बड़ा bag)

मुख्य बाजार

- अंतरराष्ट्रीय बाजार, के साथ अत्यावश्यक demand in North America, Europe, Asia, प्रमुख रूप से उपयोग किया गया में भोजन and beverage, pharmaceutical, cosmetics, and chemical industries

अनुप्रयोग परिदृश्य

मुख्य गुण

रासायनिक निर्माण: An organic tricarboxylic acid with the molecular तरीका C₆H₈O₇. It has three carboxyl (-COOH) टीमें, which endow it with तगड़ा acidic properties.

चाबी विकल्प

- Acidity Regulation: As a weak organic acid, it might सफलतापूर्वक संशोधित the pH लायक का विकल्प, प्रसाद ए नियमित acidic परिवेश.

- Chelating Means: It may प्रकार नियमित complexes with इस्पात ions के बराबर calcium, iron, and copper, रोक इस्पात – catalyzed oxidation and बेहतर product stability.

- रोगाणुरोधी प्रभाव: रोकता है विस्तार का सूक्ष्म जीव, yeast, and mould in acidic परिस्थितियाँ, enjoying एक नौकरी में भोजन preservation.

- स्वाद संवर्द्धन: इसका कड़वा शैली कर सकना सुधार स्वाद का भोजन और पेय, और स्थिरता sweetness.

अनुप्रयोग परिदृश्य

1. भोजन and Beverage व्यापार

Acidulant and स्वाद Enhancer

- बड़े पैमाने पर में उपयोग किया गया smooth drinks, fruit juices, jams, candies, and dairy माल. In carbonated पेय, यह आपूर्ति a refreshing कड़वा शैली and helps to स्थिरता the sweetness of sugar. उदाहरण के लिए, in cola – क्रम से लगाना पेय, the addition of 0.1 – 0.3% citric acid can सुधार the general स्वाद.

- In canned fruits and jams, it not अकेले adjusts the acidity लेकिन इसके अलावा रोकता विस्तार of microorganisms, extending the shelf lifetime of माल.

pH Regulator

- में उपयोग किया गया cheese उत्पादन to regulate the pH लायक of milk, बिक्री the coagulation of casein and the formation of cheese curds.

- के अंदर उत्पादन of pickles, it controls the pH of the brine निश्चित करना पारंपरिक प्रगति of lactic acid सूक्ष्म जीव और the standard of pickles.

2. फार्मास्युटिकल व्यापार

Acid – base Regulator in Drug Formulations

- के अंदर preparation of oral liquids, syrups, and injection विकल्प, इसका इस्तेमाल किया गया to regulate the pH लायक निश्चित करना the steadiness and efficacy of medication. उदाहरण के लिए, in some vitamin C injection विकल्प, citric acid is added to take care of an acceptable पीएच परिवेश.

Chelating Agent

- As a chelating agent, it might उलझा हुआ साथ इस्पात ions in दवा रोक लेना drug oxidation and degradation, and बढ़ाना the steadiness of medication.

3. Cosmetics and निजी देखभाल

pH Adjustment

- Added to facial cleansers, toners, and लोशन to regulate the pH लायक का माल to a डिग्री उपयुक्त for the त्वचा (अक्सर मुश्किल से acidic), सेवा करना to take care of पारंपरिक अभिनय करना की त्वचा barrier.

एंटीऑक्सीडेंट और परिरक्षक

- In some त्वचा – care माल, its chelating मतलब कर सकना पहिले से ग्रहण करना the catalytic oxidation of इस्पात ions के अंदर तरीका, और पर समान time, its acidic परिवेश can inhibit विस्तार of microorganisms, enjoying एक नौकरी in product preservation.

4. रासायनिक व्यापार

Chelating Agent in Electroplating

- के अंदर electroplating का कोर्स, इसका used as a chelating agent to उलझा हुआ साथ इस्पात ions के अंदर plating उत्तर, बेहतर the uniformity and उच्च गुणवत्ता of the plating layer.

Water उपचार

- As a water – softening agent, it might chelate with calcium and magnesium ions in water, कम water hardness and रोक the formation of scale in water – उपयोग gear.

5. अलग Industries

खिलाना व्यापार

- Added to animal feed as an acidulant and स्वाद enhancer, which might बढ़ाना the palatability of feed, promote the digestion and absorption of feed by animals, and पर समान time inhibit विस्तार का खतरनाक microorganisms in feed.

Textile व्यापार

- इस्तेमाल किया गया के अंदर textile dyeing and ending का कोर्स as a pH regulator and chelating agent बढ़ाने के लिए the dyeing प्रभाव और shade fastness of materials.

खोज रणनीतियाँ

अत्यधिक – क्षमता तरल क्रोमैटोग्राफी (एचपीएलसी)

- स्तंभ: C18 (250 × 4.6 मिमी, 5 μm), सेलुलर अनुभाग: 0.1% phosphoric acid उत्तर – methanol (95:5, v/v), प्रसार शुल्क: 1.0 mL/min, Detection Wavelength: 210 nm. This तकनीक कर सकना एकदम सही quantify the सामग्री of citric acid in बहुत samples.

टाइट्रेट करना क्रियाविधि

- उपयोग a normal sodium hydroxide उत्तर for acid – base titration, with phenolphthalein as an indicator, तलाश करना the सामग्री of citric acid. This can be a traditional और आम तौर पर used detection तकनीक, विशेष रूप से उपयुक्त for easy samples.

Ion Chromatography

- Can इसके साथ-साथ separate and detect बहुत anions के साथ साथ citrate ions, with अत्यधिक sensitivity and good reproducibility, उपयुक्त for the मूल्यांकन का उलझा हुआ samples containing की एक संख्या तत्वों.

आपूर्ति और फ़ायदे

उत्पादन रणनीतियाँ

- प्रमुख रूप से produced by fermentation of carbohydrates (के बराबर glucose) उपयोग Aspergillus niger. This जैविक fermentation तकनीक है the benefits of अत्यधिक yield, low कीमत, and environmental friendliness.

बहुमुखी प्रयोजनों

- इसका की एक संख्या गुण के बराबर acidity, chelating मतलब, और स्वाद – enhancing अभिनय करना इसे बनाएं मोटे तौर पर में उपयोग किया गया बहुत industries, विधानसभा the various चाहता हे of various fields.

सुरक्षित उपलब्ध करवाना

- With mature उत्पादन विशेषज्ञता और a big – scale industrial उत्पादन पुतला, it might गारंटी ए नियमित market उपलब्ध करवाना, और the worth is comparatively नियमित.

नियामक अनुमोदन

- आम तौर पर स्वीकार किया जैसा संरक्षित (GRAS) बहुत सारे में अंतर्राष्ट्रीय स्थानों और क्षेत्रों, and has clear नियम और आवश्यकताएं for its use in numerous industries, which is conducive to its broad उपयोगिता.

श्रेणियाँ: कार्यात्मक खाद्य पदार्थों, पेय पदार्थ जोड़ना, सौंदर्य प्रसाधन और व्यक्तिगत देखभाल, खाद्य योज्य, स्वास्थ्य उत्पाद, स्वास्थ्य सेवा और फार्मास्युटिकल सामग्री, प्राकृतिक पौधों के अर्क

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Citric Acid: Nature’s Versatile Natural Powerhouse | Shaanxi Zhonghong Funding Expertise

1. What is Citric Acid?

Citric acid (C₆H₈O₇) is a weak, tricarboxylic organic acid naturally occurring in citrus fruits like lemons, limes, oranges, and grapefruits. It serves as a key intermediate metabolite within the Krebs cycle (citric acid cycle), the first energy-producing pathway in cardio organisms. Industrially, it is one of the crucial broadly used organic acids as a result of its glorious solubility, nice bitter style, chelating properties, and buffering capability. It exists as a white, crystalline powder and is extremely water-soluble.

2. Supply, Chemical Properties & Key Identifiers

Main Supply: Traditionally extracted from citrus juice. Trendy industrial manufacturing (><｜finish▁of▁pondering｜> of world provide) makes use of submerged fermentation of carbohydrate sources (e.g., molasses, corn starch hydrolysates) by the filamentous fungus एस्परजिलस नाइजर.
रासायनिक गुण:
- आणविक प्रणाली: C₆H₈O₇
- उपस्थिति: Colorless crystals or white crystalline powder.
- गंध: Odorless.
- Style: Strongly acidic, nice bitter style.
- घुलनशीलता: Extremely soluble in water, ethanol, and diethyl ether.
- pKa Values: pKa₁ = 3.13, pKa₂ = 4.76, pKa₃ = 6.40 (at 25°C). This makes it an efficient buffer over a spread related to meals and organic methods.
- Chelation: Types secure complexes (chelates) with steel ions (e.g., Ca²⁺, Mg²⁺, Fe³⁺), essential for its position in cleansing brokers, meals preservation, and stopping oxidation.
प्रमुख पहचानकर्ता:
- CAS रजिस्ट्री मात्रा: 77-92-9 (Anhydrous) | 5949-29-1 (Monohydrate)
- आणविक प्रणाली (एमएफ): C₆H₈O₇
- आणविक भार (MW): 192.124 g/mol (Anhydrous) | 210.14 g/mol (Monohydrate)
- EINECS मात्रा: 201-069-1

3. Benefits, Security, & Issues

“Greatest” Citric Acid: The “finest” depends upon software. Meals/pharma grades require excessive purity (USP/BP/EP/FCC). Beauty grades want particular purity and microbial management. Shaanxi Zhonghong ensures >99.5% purity, exceeding typical business requirements (typically ~99%), guaranteeing superior efficiency and security.
Pores and skin Benefits:
- Alpha Hydroxy Acid (AHA): Features as a gentle AHA, selling light exfoliation by breaking down desmosomes between corneocytes.
- pH Adjustment: Vital for formulating inside the pores and skin’s optimum acidic mantle (pH 4.5-5.5), enhancing barrier operate.
- Antioxidant & Chelation: Mitigates oxidative stress from free radicals and steel ions (e.g., Fe²⁺ concerned in Fenton reactions).
- Brightening: Inhibits tyrosinase exercise and reduces melanin switch, aiding in hyperpigmentation administration. Enhances penetration of different energetic elements.
Well being Benefits & Dietary Consumption:
- Power Metabolism: Central to the mitochondrial Krebs cycle (ATP manufacturing).
- Mineral Absorption: Chelates minerals, probably enhancing bioavailability (e.g., some types of calcium citrate).
- Urinary Well being: Alkalinizes urine, probably stopping sure varieties of kidney stones (uric acid, cystine stones).
- एंटीऑक्सीडेंट गुण: Contributes to mobile antioxidant defenses.
- प्रतिदिन उपभोग: Citric acid is Typically Acknowledged As Protected (GRAS) by the FDA and authorised globally (EFSA, JECFA). No established Acceptable Each day Consumption (ADI) exists as a result of it is a regular physique metabolite. Consumption is restricted by palatability and gastrointestinal tolerance. Typical consumption is by way of meals and drinks.
Potential Facet Results & Precautions:
- Dental Erosion: Extremely acidic meals/drinks containing citric acid can erode tooth enamel with frequent publicity.
- GI Irritation: Excessive concentrations might trigger heartburn or abdomen upset in delicate people.
- Pores and skin Irritation: Undiluted citric acid powder or high-concentration options could cause irritation, stinging, or chemical burns. Beauty formulations are rigorously pH-balanced.
- Eye Contact: Extreme irritant. Requires fast flushing.
- Chelation: Can bind important minerals; important dietary imbalance is unlikely however potential with extreme supplementation.
- दवा पारस्परिक क्रिया: Might have an effect on absorption of sure drugs (e.g., aluminum-containing antacids, some antibiotics). Seek the advice of a healthcare supplier.

4. Shaanxi Zhonghong Funding Expertise: Your Trusted Citric Acid Companion

Shaanxi Zhonghong Investment Technology Co., Ltd. stands as a premier high-tech enterprise integrating agile R&D, collaborative innovation, built-in manufacturing, and international advertising and marketing. We concentrate on serving the chemical, materials, and life science sectors, with deep experience within the extraction, separation, purification, and market software of bioactive plant constituents.

मूल दक्षताएं:
- वैज्ञानिक कौशल: Strategic alliances with 5 main universities underpin our 20+ patented applied sciences and distinctive international compound library.
- विनिर्माण उत्कृष्टता: Using cutting-edge analytical instrumentation together with उच्च-प्रदर्शन तरल क्रोमैटोग्राफी (एचपीएलसी) और अतिचालक नाभिकीय चुंबकीय अनुनाद (NMR) spectrometers. Our stringent high quality management ensures citric acid purity exceeding business benchmarks by >20%.
- अंतर्राष्ट्रीय उपलब्धि: An intensive distribution community serving 80+ international locations throughout Asia, Europe, and the Americas. We offer bespoke ingredient options to multinational pharmaceutical firms, analysis establishments, and main producers.
- पुष्टिकृत अनुभव: Leveraging 28 years of devoted expertise within the bioactive compounds business.

5. Product Specs: Rigorous High quality Assurance

Shaanxi Zhonghigh’s Citric Acid meets or exceeds main pharmacopoeial requirements (USP/BP/EP) and FCC necessities for meals grade. Our dedication to purity and security is demonstrated via complete testing:

संदूषक वर्ग	पैरामीटर	विनिर्देश	जाँच तकनीक
कीटनाशक अवशेष	Chlorpyrifos	≤ 0.01 मिलीग्राम/किग्रा	जीसी-एमएस/एमएस, एलसी-एमएस/एमएस
	डाइक्लोरवोस	≤ 0.01 मिलीग्राम/किग्रा	जीसी-एमएस/एमएस, एलसी-एमएस/एमएस
	साइपरमेथ्रिन	≤ 0.01 मिलीग्राम/किग्रा	जीसी-एमएस/एमएस, एलसी-एमएस/एमएस
	DDT (Complete Isomers)	≤ 0.05 मिलीग्राम/किग्रा	जीसी-ईसीडी, जीसी-एमएस/एमएस
	हेक्साक्लोरोबेंजीन	≤ 0.01 मिलीग्राम/किग्रा	जीसी-एमएस/एमएस
हैवी मेटल्स	सीसा (Pb)	≤ 1.0 मिलीग्राम/किग्रा	ICP-MS, AAS (Graphite Furnace)
	आर्सेनिक (As)	≤ 1.0 मिलीग्राम/किग्रा	ICP-MS, HG-AAS
	कैडमियम (Cd)	≤ 0.5 मिलीग्राम/किग्रा	ICP-MS, AAS (Graphite Furnace)
	पारा (Hg)	≤ 0.1 मिलीग्राम/किग्रा	CV-AAS, ICP-MS
जीवाणुतत्व-संबंधी	पूर्ण प्लेट भरोसा	≤ 1000 सीएफयू/जी	आईएसओ 4833-1
	खमीर और फफूंदी	≤ 100 सीएफयू/जी	आईएसओ 21527-1, -2
	इशरीकिया कोली	10 ग्राम में अनुपस्थित	आईएसओ 16649-2
	साल्मोनेला एसपीपी.	25 ग्राम में अनुपस्थित	आईएसओ 6579-1
	स्टाफीलोकोकस ऑरीअस	1g में अनुपस्थित	ISO 6888-1, -2

6. Manufacturing Course of: Precision Fermentation & Purification

Our citric acid manufacturing leverages state-of-the-art submerged fermentation expertise:

Substrate Preparation: Excessive-quality carbohydrate sources (e.g., non-GMO corn starch hydrolysate) are sterilized and conditioned.
किण्वन: एस्परजिलस नाइजर is cultivated beneath meticulously managed situations (pH, temperature, aeration, nutrient feed) to maximise citric acid yield.
Mycelium Separation: The fungal biomass is eliminated by way of filtration or centrifugation.
शुद्धिकरण: The broth undergoes lime remedy (precipitation as calcium citrate), adopted by sulfuric acid regeneration to yield citric acid answer.
क्रिस्टलीकरण: The answer is concentrated and crystallized (anhydrous or monohydrate types).
सुखाने और मिलिंग: Crystals are dried to express moisture specs and milled to desired particle dimension distribution.
उच्च गुणवत्ता प्रबंधन: Rigorous in-process and ultimate product testing (HPLC, NMR, ICP-MS, microbiological) ensures compliance with specs.

7. अनुप्रयोग परिदृश्य

Citric acid’s versatility spans quite a few industries:

Meals & Beverage (F&B): Main acidulant (tender drinks, juices, candies), taste enhancer, pH adjuster, preservative (chelates steel catalysts of oxidation), antioxidant synergist, emulsifying support in processed cheeses.
निर्धारित दवाएँ: Excipient (effervescent formulations, taste masking, pH adjustment in syrups and injections), anticoagulant (blood assortment tubes), chelator in steel cleansing.
सौंदर्य प्रसाधन और निजी देखभाल: pH adjuster (lotions, lotions, shampoos), chelating agent (stabilizes formulations, enhances preservative efficacy), AHA for exfoliation and brightening (serums, peels), antioxidant.
Family & Industrial Cleaners: Key chelating agent in descaling brokers, dishwasher detergents, lavatory cleaners (removes onerous water stains, rust, lime scale), biodegradable various to phosphates.
Water Remedy: pH adjustment, chelation of steel ions to forestall scaling/corrosion.
Different: Textile processing (dyeing, printing), pictures, oilfield chemical substances, concrete setting retardant.

8. High quality Management (QC): Dedication to Excellence

At Shaanxi Zhonghong, QC is paramount. Our built-in QC system ensures constant, premium citric acid:

कच्ची सामग्री की जांच: Strict protocols for incoming carbohydrate sources and different inputs, together with id, purity, and contaminant testing.
In-Course of Controls: Actual-time monitoring of crucial fermentation parameters (pH, dissolved oxygen, temperature, sugar focus) and purification steps. Automated methods set off alerts for deviations.
बेहतर विश्लेषण: Our ISO 17025 accredited lab makes use of HPLC-UV/ELSD/RID for exact quantification and impurity profiling, ICP-MS/OES for hint heavy metals, GC-MS/MS/LC-MS/MS for pesticide residues, validated microbiological strategies (ISO requirements), कार्ल फिशर अनुमापन for moisture, and Potentiometric Titration for assay. एफटीआईआर और एनएमआर verify structural id.
स्थिरता अनुसंधान: Ongoing research beneath ICH tips to ascertain shelf life and storage suggestions.
दस्तावेज़ीकरण एवं पता लगाने योग्यता: Complete batch information and digital knowledge administration guarantee full traceability from uncooked materials to completed product.
अनुपालन: Adherence to cGMP, HACCP, ISO 9001, and related pharmacopoeial/meals security rules (FDA, EFSA).

9. पैकेजिंग और लॉजिस्टिक्स

पैकेजिंग: Provided in numerous codecs to go well with buyer wants: 25kg multi-layer kraft paper baggage with polyethylene liner (normal), 1000kg bulk baggage (FIBCs), or customized packaging upon request. All packaging ensures product integrity, moisture safety, and meets worldwide transport rules (IMDG, IATA).
रसद: Leveraging our international community, we offer environment friendly, dependable logistics options by way of sea, air, or land freight. Experience in dealing with customs clearance and documentation for seamless worldwide supply.

10. Well being Efficacy, Functions & Analysis Frontiers

स्वास्थ्य तंत्र: Past its position within the Krebs cycle, analysis explores citric acid’s potential in modulating irritation, enhancing mineral solubility within the intestine, and its position in bone well being (by way of citrate in apatite). Its urinary alkalinization mechanism includes metabolism to bicarbonate.
औद्योगिक नवाचार: Focus areas embody optimizing fermentation strains (A. niger engineering) for greater yields and lowered byproducts, growing novel purification methods (e.g., membrane filtration, steady chromatography) for sustainability, and exploring new functions in inexperienced chemistry (biodegradable chelators, catalyst synthesis).
Analysis Challenges: Key challenges embody decreasing the environmental footprint of manufacturing (water/vitality use, waste streams), enhancing cost-effectiveness for bulk functions, and absolutely elucidating its therapeutic potential at supra-dietary doses in particular situations.

11. Citric Acid FAQ

Q: Is citric acid pure? A: Sure, it happens naturally in citrus fruits. Most business citric acid is produced by way of microbial fermentation, a pure course of, utilizing plant-derived carbohydrates.
Q: Is citric acid protected? A: Sure, citric acid is GRAS (Typically Acknowledged As Protected) by the FDA and authorised globally to be used in meals, prescription drugs, and cosmetics when used appropriately.
Q: Can citric acid expire? A: When saved correctly (cool, dry place in sealed containers), high-purity citric acid is extraordinarily secure. It could take up moisture over very lengthy intervals however stays functionally efficient. Shelf life is usually 3-5 years.
Q: Does citric acid kill micro organism? A: Whereas acidic situations can inhibit some microbial progress, citric acid is primarily a preservative enhancer via chelation and pH discount. It really works synergistically with different preservatives (e.g., in meals and cosmetics).
Q: Can I exploit citric acid for cleansing? A: Completely! It is extremely efficient as a descaling agent for kettles, espresso makers, showerheads, and eradicating onerous water stains. Dilute 1-2 tablespoons per cup of heat water.
Q: How does citric acid profit pores and skin? A: As an AHA, it gently exfoliates useless pores and skin cells, improves texture and radiance, helps fade darkish spots, adjusts pH to help the pores and skin barrier, and acts as an antioxidant.

12. The place to Purchase Excessive-Purity Citric Acid?

Supply premium, high-purity (>99.5%) Citric Acid instantly from the producer:

वेबसाइट: https://www.aiherba.com
संपर्क करना: श्री लियाओ दाओहाई
इलेक्ट्रॉनिक मेल: liaodaohai@gmail.com
प्रदाता: शानक्सी झोंगहोंग निवेश प्रौद्योगिकी कं, लिमिटेड

13. निष्कर्ष

Citric acid is an indispensable, multi-functional compound with profound significance throughout organic methods and huge industrial functions. From energizing mobile metabolism to preserving meals, enhancing cosmetics, and powering eco-friendly cleaners, its versatility is unmatched. Shaanxi Zhonghong Investment Technology Co., Ltd. delivers citric acid of outstanding purity and consistency, backed by superior fermentation expertise, rigorous high quality management exceeding business requirements, and 28 years of experience in bioactive compounds. We’re dedicated to offering tailor-made, dependable options for international companions in prescription drugs, meals, cosmetics, and past. Contact us in the present day in your citric acid necessities.

14. संदर्भ

PubChem Compound Abstract: Citric Acid. Nationwide Library of Drugs. https://pubchem.ncbi.nlm.nih.gov/compound/Citric-acid
Meals and Agriculture Group (FAO). Citric Acid. JECFA Monographs. https://www.fao.org/
U.S. Meals & Drug Administration (FDA). SCOGS Database: Citric Acid. https://www.fda.gov/
European Meals Security Authority (EFSA). Re-evaluation of citric acid (E 330)… EFSA Journal.
Soccol, C. R., et al. (2006). Citric acid manufacturing. Meals Expertise and Biotechnology.
Beauty Ingredient Evaluate (CIR). Security Evaluation of Citric Acid… Worldwide Journal of Toxicology.
Max, B., et al. (2010). Citric acid manufacturing. Latest Patents on Biotechnology.
Related Pharmacopoeias: United States Pharmacopeia (USP), European Pharmacopoeia (Ph. Eur.), British Pharmacopoeia (BP), Meals Chemical substances Codex (FCC).

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