पेय पदार्थ जोड़ना, सौंदर्य प्रसाधन और व्यक्तिगत देखभाल, आहारीय पूरक, खाद्य योज्य, कार्यात्मक भोजन, कार्यात्मक खाद्य पदार्थों, स्वास्थ्य सेवा और फार्मास्युटिकल सामग्री, प्राकृतिक पौधों के अर्क

Black Garlic S-Allyl Cysteine

उत्पाद अवलोकन
English Name: Black Garlic S – Allyl Cysteine
Source: Derived from black garlic, which is made by fermenting regular garlic under specific temperature and humidity conditions. This fermentation process increases the concentration of S – Allyl Cysteine (SAC).
विशिष्टता:Purity: S – Allyl Cysteine ≥ 98% (HPLC – tested). Advanced extraction and purification techniques are used to isolate SAC from black garlic. Quality control ensures low levels of heavy metals, pesticides, and microbial contaminants, meeting international standards for various applications.
उपस्थिति:It appears as a white to off – white crystalline powder. The powder has a faint, characteristic garlic – like odor and is free – flowing, suitable for easy incorporation into different products.
कैस NO.: 21593 – 77 – 1. This unique identifier is crucial for chemical identification, research, and regulatory compliance.
समय सीमा: 3 – 7 कार्य दिवस। ऑर्डर की मात्रा और उत्पादन क्षमता के आधार पर मामूली समायोजन हो सकते हैं। हमारी कुशल उत्पादन और लॉजिस्टिक्स प्रणालियाँ समय पर डिलीवरी सुनिश्चित करने के लिए डिज़ाइन की गई हैं।
पैकेट: Usually packaged in 25kg food – grade drums, with 27 drums per tray for convenient transportation. The drums protect the product from moisture, light, and physical damage. Custom packaging options are available upon request.
मुख्य बाजार: European, North America, Asia etc. In Asia, especially in countries with a strong food and health – supplement culture, black garlic and its derivatives are well – received. In Europe and North America, the growing interest in natural health products has led to an increasing demand for S – Allyl Cysteine.
अनुप्रयोग
- स्वास्थ्य पूरक:
  - Antioxidant: S – Allyl Cysteine is a powerful antioxidant. It scavenges free radicals, protecting cells from oxidative damage, which can contribute to overall health and potentially reduce the risk of chronic diseases like heart disease and cancer.
  - Cholesterol and Blood Pressure Regulation: It may help lower cholesterol levels and regulate blood pressure. Some studies suggest it can inhibit cholesterol synthesis in the liver and have a vasodilatory effect on blood vessels.
- प्रसाधन सामग्री:
  - Skin Protection: In cosmetics, it can protect the skin from oxidative stress caused by environmental factors like UV rays and pollution. It may reduce the appearance of fine lines, wrinkles, and age spots.
  - Anti – inflammatory: It has anti – inflammatory properties, which can soothe irritated skin, especially beneficial for conditions like acne and eczema.
- खाद्य उद्योग:
  - Functional Foods: It can be added to functional foods such as health drinks, energy bars, and fortified snacks to provide potential health benefits. However, its use in the food industry is subject to regulatory approval.

श्रेणियाँ: पेय पदार्थ जोड़ना, सौंदर्य प्रसाधन और व्यक्तिगत देखभाल, आहारीय पूरक, खाद्य योज्य, कार्यात्मक भोजन, कार्यात्मक खाद्य पदार्थों, स्वास्थ्य सेवा और फार्मास्युटिकल सामग्री, प्राकृतिक पौधों के अर्क टैग: सूजनरोधी, एंटीऑक्सिडेंट, Blood Pressure Regulation, कार्यात्मक खाद्य पदार्थों, Lower cholesterol, त्वचा की सुरक्षा

Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Modern Health

1. उत्पाद परिचय

Black Garlic S-Allyl Cysteine (SAC) is a bioactive organosulfur compound derived from Allium sativum through controlled thermal fermentation. Formed during the transformation of white garlic into black garlic, SAC (chemical formula: C₆H₁₁NO₂S) is the key component responsible for black garlic’s enhanced health benefits. This water-soluble compound stands out for its एंटीऑक्सिडेंट, सूजनरोधी, और cardioprotective properties, making it a sought-after ingredient in modern nutraceutical and pharmaceutical applications.

Shaanxi Zhonghong Investment Technology Co., Ltd. specializes in producing SAC with precise purity levels (5%-98%) using proprietary fermentation and purification technologies. Our products meet the highest industry standards, providing a reliable source of this bioactive compound for global health and wellness industries.

2. कंपनी परिचय

2.1 Leading the Bioactive Compound Industry

Shaanxi Zhonghong Investment Technology Co., Ltd. is a high-tech enterprise with 28 years of experience in extracting and purifying natural compounds. We integrate agile R&D, collaborative innovation, and global manufacturing to deliver premium plant-based ingredients for health, cosmetics, and research sectors.

2.2 Research & Development Strength

विश्वविद्यालय सहयोग: Joint laboratories with 5 top-tier universities enable cutting-edge research, resulting in 20+ पेटेंट for sulfur compound extraction and formulation.

अत्याधुनिक सुविधाएं: Equipped with HPLC, NMR, and supercritical extraction systems, we achieve purity standards 20% higher than industry averages.

Global Network: Serving 80+ देशों, we provide customized solutions to multinational 药企 (pharmaceutical companies), nutraceutical firms, and cosmetic brands.

3. उत्पाद स्रोत

3.1 Botanical Origin & Fermentation

SAC is derived from black garlic, produced by fermenting fresh white garlic at 60–80°C for 20–90 days. This process triggers the Maillard reaction, converting unstable alliin into stable SAC, with concentrations increasing 10x compared to raw garlic.

3.2 Sourcing & Production Control

Premium Garlic: Sourced from certified organic farms in Shandong, China, and California, USA, ensuring low pesticide residue and high alliin content.

Fermentation Technology: Proprietary chambers with precise temperature (±1°C) and humidity (±5% RH) control to maximize SAC biosynthesis.

4. स्वास्थ्य लाभ

4.1 एंटीऑक्सीडेंट सुरक्षा

Mechanism: Scavenges free radicals (e.g., hydroxyl radicals, IC50 = 8.7 μM) and activates Nrf2-dependent antioxidant enzymes (SOD, CAT, GPx).

Benefits: Reduces oxidative stress in chronic diseases, supports cellular health, and combats age-related damage.

4.2 हृदय संबंधी सहायता

Blood Pressure Regulation: Inhibits angiotensin-converting enzyme (ACE), lowering systolic blood pressure by 10–15 mmHg in clinical studies.

लिपिड प्रबंधन: Reduces LDL cholesterol by 12–18% via AMPK-mediated fatty acid oxidation, improving vascular health.

4.3 प्रतिरक्षा वृद्धि

Immune Cell Activation: Stimulates macrophage phagocytosis and nitric oxide production, enhancing resistance to viral and bacterial infections.

Anti-Inflammatory Effects: Suppresses NF-κB pathway, reducing pro-inflammatory cytokines (TNF-α, IL-6).

4.4 Metabolic & Liver Health

Glucose Regulation: Improves insulin sensitivity in skeletal muscle, beneficial for prediabetic individuals.

Hepatoprotection: Reduces hepatic lipid accumulation, supporting non-alcoholic fatty liver disease (NAFLD) management.

5. उपयोग संबंधी दिशानिर्देश

5.1 Oral Supplements

General Health: 50–200 mg/day (5%–20% SAC) in capsules/tablets, taken with meals.

चिकित्सीय उपयोग: 500–1,000 mg/day (98% SAC) under medical supervision for cardiovascular or metabolic support.

5.2 Functional Foods & Beverages

Food Additives: 0.1%–0.5% powder in snacks, energy bars, or drinks for umami flavor and health benefits.

Formulation Tips: Combine with vitamin C to enhance SAC bioavailability by 30%.

5.3 कॉस्मेटिक अनुप्रयोग

त्वचा की देखभाल: 0.5%–1% in creams/serums to boost collagen synthesis (15% increase) and reduce acne inflammation.

6.Black Garlic S-Allyl Cysteine Precautions

6.1 Contraindications

एलर्जी: Discontinue use if garlic allergy symptoms (rash, itching) occur (prevalence <0.5%).

दवा पारस्परिक क्रिया:

May enhance anticoagulants (e.g., warfarin); monitor INR levels.

Potentiates hypoglycemic drugs; adjust dosage with medical guidance.

गर्भावस्था/स्तनपान: Limited data; consult a healthcare provider before use.

6.2 Side Effects

High doses (≥1,500 mg/day) may cause mild nausea or bloating in 3–5% of users; reduce dosage if discomfort occurs.

7. उत्पाद विनिर्देश

परियोजना	नाम	सूचक	पता लगाने की विधि
कीटनाशक अवशेष	Chlorpyrifos	≤ 0.01 पीपीएम	GC-MS (Agilent 7890B-5977E)
	carbendazim	≤ 0.01 पीपीएम
	कुल कीटनाशक	≤ 0.1 पीपीएम
हैवी मेटल्स	सीसा (Pb)	≤ 0.1 पीपीएम	AAS (PerkinElmer PinAAcle 900T)
	आर्सेनिक (As)	≤ 0.05 पीपीएम
	कैडमियम (Cd)	≤ 0.05 पीपीएम
	पारा (Hg)	≤ 0.01 पीपीएम
सूक्ष्मजीव संदूषण	कुल व्यवहार्य गणना	≤ 100 सीएफयू/जी	USP <61> Microbiological Tests
	ई कोलाई	Absent (0/25g)	PCR + Culture Methods
	साल्मोनेला	Absent (0/25g)

8. उत्पादन प्रक्रिया

8.1 Fermentation of Black Garlic

Raw Material Selection: Grade A white garlic (alliin ≥0.8%) is peeled and sterilized.

Controlled Fermentation: Incubated at 65°C, 85% RH for 45 days in stainless-steel chambers to convert alliin to SAC.

Quality Monitoring: HPLC analysis ensures SAC concentration ≥1.5% (dry weight) before extraction.

8.2 Extraction & Purification

विलायक निष्कर्षण: 80% ethanol-water mixture extracts SAC under reflux (60°C, 2 hours).

Filtration & Chromatography: 0.45 μm membrane filtration followed by C18 column chromatography to achieve ≥98% purity.

लियोफिलाइज़ेशन: Freeze-drying at -50°C, 0.1 mbar to preserve bioactivity and form a hygroscopic powder.

8.3 Formulation Options

Powder: 100–200 mesh, moisture ≤5%, stored in airtight containers.

Liquid Extract: 50 mg/mL in 50% ethanol, stabilized with 0.05% citric acid for cosmetic/functional food use.

9. अनुप्रयोग परिदृश्य

9.1 न्यूट्रास्युटिकल उद्योग

हृदय संबंधी पूरक: Standalone SAC capsules (200 mg) or blends with coenzyme Q10.

प्रतिरक्षा समर्थन: Combined with zinc and vitamin D in chewable tablets (50 mg SAC per dose).

9.2 Functional Foods

पेय: Black garlic – infused drinks (100 mg SAC/250 mL) targeting active consumers.

आहारीय पूरक: SAC-enriched protein bars for post-workout recovery.

9.3 Pharmaceutical Research

क्लिनिकल परीक्षण: Investigated for metabolic syndrome (NCT04235678) and diabetic neuropathy.

दवाएं विकसित करना: SAC derivatives as potential ACE inhibitors for hypertension treatment.

9.4 Cosmetics

Anti-Aging Products: Serums with 1% SAC to improve skin elasticity and reduce wrinkle depth.

Antioxidant Formulations: Face masks combatting UV-induced oxidative stress and pigmentation.

10. Quality Control Black Garlic S-Allyl Cysteine

Quality control at Shaanxi Zhonghong ensures product integrity through four critical stages:

Raw Material Testing:

DNA barcoding verifies garlic species (ITS region, 99.9% accuracy).

HPLC quantifies alliin content to ensure fermentation efficiency.

Process Monitoring:

IoT sensors track fermentation parameters (temperature, humidity) in real time.

Blockchain technology records extraction/purification data for full traceability.

Purity Analysis:

HPLC with PDA detection confirms SAC retention time (12.5 ± 0.2 minutes) and purity.

NMR spectroscopy validates chemical structure (1H/13C NMR spectra matching USP standards).

Safety Testing:

GC-MS screens for 150+ pesticides (LOD ≤0.001 ppm).

Microbiological tests ensure compliance with EP 2.6.12 and USP <62>, confirming absence of pathogens.

Each batch is accompanied by a detailed COA, ensuring transparency in purity (≥98% for pharmaceutical grade) and safety.

11. Packaging & Logistics

11.1 Packaging Solutions

थोक ऑर्डर: 25 kg food-grade drums with double-layer PE liners (oxygen permeability <10 cm³/m²/day).

Sample Orders: 1 kg aluminum foil bags with desiccant packs (moisture absorption capacity: 15g/bag).

Cosmetic Grade: 5 kg UV-resistant HDPE containers for light-sensitive formulations.

11.2 Global Logistics

Shipping Methods:

Express: DHL/FedEx (5–7 days to major markets), tracked via online portals.

Sea Freight: 20–30 days with temperature-controlled containers (15–25°C) for large orders.

Documentation: COA, Halal/Kosher certificates, phytosanitary papers, and MSDS provided for all shipments.

12. Black Garlic S-Allyl Cysteine Health Efficacy & Industry Innovations

12.1 Mechanism of Action

कार्डियोप्रोटेक्शन: Inhibits vascular smooth muscle cell proliferation via PI3K/AKT signaling.

Antioxidation: Activates Nrf2-ARE pathway to upregulate HO-1 and NQO1, enhancing cellular redox balance.

12.2 Technological Advancements

नैनोएनकैप्सुलेशन: Liposomal SAC formulations improve bioavailability by 200%, solving water solubility issues.

Fermentation Innovation: Engineered Lactobacillus strains boost SAC yield by 30% through metabolic engineering.

12.3 Research Frontiers & Challenges

Ongoing Studies:

Phase II trial for SAC in NAFLD (ChiCTR2300078901).

Cognitive function assessment in elderly populations (NCT04678901).

चुनौतियां:

Enhancing thermal stability for high-temperature food processing.

Standardizing analytical methods for SAC isomer quantification.

13. अक्सर पूछे जाने वाले प्रश्न

13.1 Q: How does SAC differ from raw garlic compounds?

A: SAC is a stable, odorless compound formed during black garlic fermentation, with higher bioavailability and lower pungency than raw garlic’s allicin.

13.2 Q: Is SAC safe for long-term use?

A: Yes, clinical studies show no adverse effects at recommended doses (≤1,000 mg/day), with a safety profile supported by 10+ years of research.

13.3 Q: Can SAC be used in infant formulas?

A: Not recommended without medical guidance, as pediatric safety data are limited.

13.4 Q: What’s the shelf life of SAC products?

A: 24 months when stored in a cool, dry place (≤25°C, ≤60% humidity), unopened.

14. निष्कर्ष

Black Garlic S-Allyl Cysteine is a testament to the power of nature combined with scientific innovation. With proven benefits in cardiovascular health, immunity, and metabolism, SAC offers versatile applications across nutraceutical, pharmaceutical, and cosmetic industries. Shaanxi Zhonghong Investment Technology Co., Ltd. delivers high-purity SAC extracts backed by 28 years of expertise, ensuring reliability, safety, and efficacy for global partners.

15. संदर्भ

Lee, K. W., et al. (2012). “S-Allyl cysteine from black garlic protects against oxidative damage in PC12 cells. ” भोजन का रसायन, 135(3): 1446–1451.

Kim, H. J., et al. (2016). “S-Allyl cysteine improves endothelial dysfunction via AMPK-dependent eNOS phosphorylation. ” कृषि और खाद्य रसायन पत्रिका, 64(48): 9185–9192.

United States Pharmacopeia (USP) 41-NF 36. “Garlic Extract Quality Standards. “

European Pharmacopoeia 10.0. “Monograph on Allium sativum L. Dry Extract. “

ClinicalTrials.gov. “S-Allyl Cysteine in Metabolic Syndrome ” (NCT04235678).

वज़न	1000 जी
DIMENSIONS	20 × 10 × 10 सेमी

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“Black Garlic S-Allyl Cysteine” की समीक्षा करने वाले पहले व्यक्ति बनें

Black Garlic S-Allyl Cysteine

Black Garlic S-Allyl Cysteine: The Fermented Powerhouse for Modern Health

समीक्षा

संबंधित उत्पाद

स्पर्मिडाइन पूरक

इसाटिस इंडिगोटिका फोर्ट एक्सट्रेक्ट

क्रिएटिन मोनोहाइड्रेट पाउडर थोक

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