बायोपेरिन

Bioperine®: The Gold Standard in Bioavailability Enhancement – A Manufacturer’s Guide

1. What is Bioperine®?

Let’s cut through the noise. Bioperine® is not just black pepper extract. It’s a patented, clinically-studied ingredient derived from the fruits of पाइपर नाइग्रम L. (black pepper) and standardized to contain ≥95% piperine. Think of it as the key that unlocks the full potential of your supplements. Its primary, and most valuable, function is to significantly enhance the bioavailability of other active compounds, making your formulations more effective and efficient.

2. स्रोत, रसायन विज्ञान और विनिर्देश

• स्रोत: Sourced from the dried fruits of पाइपर नाइग्रम एल

• प्रमुख जैवसक्रिय: Piperine (Standardized to ≥95%).

• रासायनिक प्रोफ़ाइल:

  • CAS संख्या।: 94-62-2

  • एमएफ: C₁₇H₁₉NO₃

  • एमडब्ल्यू: 285.34 g/mol

  • ईआईएनईसीएस: 202-348-0

• उपस्थिति: Off-white to pale yellow crystalline powder.

• घुलनशीलता: Soluble in ethanol and chloroform; sparingly soluble in water.

3. The Zhonghong Standard: Why Our Bioperine® is Best for B2B
के लिए nutraceutical ingredients suppliers और private label supplement manufacturers, consistency and proof are everything. Here’s what defines a premium-grade Bioperine®:

• Key Ingredient & Potency: ≥95% Piperine. This high level of purity is non-negotiable for reliable and potent bioavailability enhancement.

• Proven Efficacy (Compliant Claims):

  • Bioavailability Enhancer: Clinically shown to increase the absorption of various nutrients (e.g., Curcumin, CoQ10, Vitamins, Selenium).

  • Thermogenic Activity: Supports metabolic rate and nutrient utilization.

  • (Note: This product is not intended to diagnose, treat, cure, or prevent any disease. Structure/function claims must be compliant with local regulations).

• Optimal Use Level: Typically used at a 1-5% ratio relative to the active compound it is enhancing (e.g., 5-10mg of Bioperine® per 500mg of Curcumin). Dosage should be finalized based on the specific formulation.

• उत्पत्ति और गुणवत्ता: प्रीमियम से प्राप्त पाइपर नाइग्रम and processed to meet stringent international standards.

• आवेदन पत्र: Ideal for incorporation into tablets, capsules, and powder formulations for dietary supplements.

• Target Formulations: Essential for private label supplement manufacturers creating products with high-value actives like turmeric/curcumin, resveratrol, multivitamins, and cognitive health blends.

• Safety & Considerations:

  • Generally Recognized as Safe (GRAS): At recommended levels.

  • दवा पारस्परिक क्रिया: May affect the metabolism of certain pharmaceutical drugs by inhibiting cytochrome P450 enzymes and UDP-glucuronylation. Consult a medical expert if formulating for populations on medication.

  • गर्भावस्था/स्तनपान: Recommended to avoid high doses.

4. Zhonghong Biotech: Your Strategic Ingredient Partner
When you need a reliable bulk botanical extracts partner, you need more than a vendor. You need a technical expert. शानक्सी झोंगहोंग निवेश प्रौद्योगिकी कं, लिमिटेड प्रमाणित है न्यूट्रास्युटिकल सामग्री आपूर्तिकर्ता with 28 years of experience in bioactive compound manufacturing.

• मुख्य विशेषज्ञता: We are specialists in the precision extraction and purification of plant-derived actives. Our portfolio is built for B2B:

  • Standardized Botanical Extracts (like Bioperine®)

  • Cosmetic Raw Material Supplier offerings

  • न्यूट्रास्युटिकल सामग्री for supplements and functional foods

  • API Intermediates

• Our B2B Value Proposition:

  • Innovation-Driven: 20+ patents and university collaborations ensure we are at the forefront of extraction technology.

  • गुणवत्ता आश्वासन: हमारा निवेश एचपीएलसी और एनएमआर स्पेक्ट्रोस्कोपी guarantees a purity standard that is consistently 20% above common industry specs, providing you with a uncontested competitive edge.

  • Global B2B Network: We supply wholesale botanical extracts और अनुकूलित समाधान को OEM हर्बल अर्क partners and major brands in over 80 countries.

5. Technical Insight: Mechanism of Action
Piperine’s primary mechanism is two-fold:

1. Inhibition of Metabolism: It inhibits the enzymes in the liver and intestine (e.g., CYP3A4, UGT) that would normally break down and eliminate other compounds before they enter the bloodstream.

2. Enhancing Absorption: It stimulates amino acid transporters in the intestinal lining and increases blood supply to the GI tract, facilitating greater uptake of co-administered supplements.

6. Uncompromising Quality Control: The COA
Our Quality Control is your formulation’s insurance policy. Every batch is rigorously tested.

Certificate of Analysis (COA) Summary – Bioperine® (≥95% Piperine)

7. उन्नत उत्पादन प्रक्रिया
Our GMP-compliant process ensures unmatched purity:

1. सोर्सिंग और तैयारी: Selection and cleaning of premium पाइपर नाइग्रम फल.

2. निष्कर्षण: Solvent extraction optimized for maximum piperine yield.

3. Filtration & Concentration: Removal of impurities and concentration of the extract.

4. Crystallization & Purification: Further refinement to achieve the ≥95% purity benchmark.

5. मानकीकरण: Precise adjustment to meet the exact specification.

6. सुखाने और मिलिंग: Conversion into a fine, free-flowing powder.

7. क्यूसी रिलीज: The batch is only released after passing all critical quality parameters.

8. Application in Nutraceutical Formulations
This ingredient is a cornerstone for effective supplement design. Its primary application is in:

• Enhanced Absorption Formulas: Curcumin supplements, multivitamins, coenzyme Q10, resveratrol, and antioxidant blends.

• Weight Management Products: Leveraging its mild thermogenic properties.

• खेल पोषण: To improve the uptake of amino acids and other performance nutrients.

9. B2B Packaging & Logistics

• पैकेजिंग: Standard 25kg/fiber drum with double polyethylene liners. Customized packaging available for थोक और थोक आदेश.

• भंडारण: Store in a cool, dry place away from strong light.

• शेल्फ जीवन: 24 months when stored correctly.

• रसद: We handle global shipping and all export documentation (COA, MSDS, Certificate of Origin) for seamless delivery to OEM partners worldwide.

10. अपनी थोक सामग्री की ज़रूरतों के लिए हमारे साथ साझेदारी करें
Zhonghong isn’t just a देने वाला; we’re your innovation partner. We provide:

• प्रतिस्पर्धी थोक मूल्य निर्धारण: प्रत्यक्ष प्राप्त करें कारखाना मूल्य उच्च मात्रा के ऑर्डर के लिए.

• अनुकूलन और OEM: हम प्रस्ताव रखते हैं OEM हर्बल अर्क और अनुकूलित समाधान tailored to your specific formulation requirements.

• Technical Support: Leverage our 28 years of expertise for your product development.

एक उद्धरण के लिए या एक नमूना अनुरोध करने के लिए हमसे संपर्क करें!

• वेब: www.aiherba.com

• ईमेल: sales@aiherba.com; liaodaohai@gmail.com

• कीवर्ड: Bioperine supplier, bulk piperine, nutraceutical ingredients supplier, cosmetic raw material supplier, wholesale botanical extracts, private label supplement manufacturer, OEM herbal extracts, bulk organic ingredients.

11. B2B ग्राहकों के लिए अक्सर पूछे जाने वाले प्रश्न

• Q: What is your Minimum Order Quantity (MOQ) for bulk orders?
  उत्तर: विशिष्ट MOQ विवरण के लिए हमसे संपर्क करें। हम लचीली शर्तें प्रदान करते हैं थोक और थोक साझेदारों.

• Q: Can you provide custom standardization for private label?
  A: Absolutely. As an OEM हर्बल अर्क partner, we specialize in अनुकूलित समाधान to meet your specific product specs.

• Q: Do you offer technical documentation and regulatory support?
  A: Yes. We provide full documentation (COA, MSDS) and can support with regulatory data for your market.

• प्रश्न: बड़े ऑर्डर के लिए लीड समय क्या है?
  A: Lead times vary based on order size. We maintain strategic stock for popular items and provide clear timelines for custom productions.

• Q: How do I start the qualification process?
  उत्तर: हमें ईमेल करें sales@aiherba.com अनुरोध करने के लिए नि: शुल्क नमूना and discuss your specific needs. Our technical team will guide you through the process.

12. निष्कर्ष
In the competitive world of supplement manufacturing, ingredient efficacy is paramount. Bioperine® is a proven, powerful tool to differentiate your products and guarantee customer results. Sourcing from a technically advanced, reliable उत्पादक is critical. Zhonghong Biotech, with its scientific rigor, proven quality, and global B2B supply capability, is the optimal partner for nutraceutical ingredients suppliers और निजी लेबल brands. Contact us today to discuss your project and request a sample.

संदर्भ:

• Majeed, M., et al. (1999). Piperine, a bioavailability enhancer. US Patent 5,972,382.

• Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. प्लांटा मेडिका, 64(4), 353-356.

• Badmaev, V., et al. (2000). Piperine, an alkaloid derived from black pepper, increases serum response of beta-carotene during 14-days of oral supplementation. Nutrition Research, 20(3), 381-388.

• Johnson, J. J., et al. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. आणविक पोषण और खाद्य अनुसंधान, 55(8), 1169-1176.