Tanshinone IIA

Tanshinone IIA: Premium Manufacturer & World Supplier for Pharmaceutical and Analysis Functions | Aiherba

 Supply high-purity Tanshinone IIA from Zhonghong, a number one producteur et fournisseur en vrac. Cardiovascular analysis compound with 98%+ purity. Demandez un patron gratuit on your R&D and get a aggressive valeur citation.

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1. What is Tanshinone IIA?

Tanshinone IIA is a distinguished lipophilic diterpenoid quinone compound and one of many main energetic constituents remoted from the basis of Salvia miltiorrhiza Bunge (Danshen or Crimson Sage), a plant deeply rooted in Conventional Chinese language Drugs. This brilliant pink crystalline compound has attracted vital scientific curiosity for its potent cardiovascular protecting results and numerous pharmacological actions. For B2B shoppers within the pharmaceutical, superior nutraceutical, and analysis sectors, a dependable Tanshinone IIA producer is crucial for sourcing a high-purity, research-grade compound for drug discovery and mechanistic research.

2. Approvisionnement, propriétés chimiques et identifiants

• Fourniture du produit : Extracted and remoted from the dried roots of Salvia miltiorrhiza Bunge.

• Composé énergétique principal : Tanshinone IIA.

• Standardisation: Sometimes accessible at excessive purity ranges: 95%, 98%, or 99%.

• Quantité CAS : 568-72-9

• Formule moléculaire (MF) : C19H18O3

• Poids moléculaire (PM) : 294.34 g/mol

• EINECS : 209-56-1

3. Deciding on the Finest Tanshinone IIA: A Information for B2B Patrons and Researchers

Pour mondial pharmaceutical firms, analysis establishments, and exportateurs, the “finest” Tanshinone IIA is outlined by its ultra-high purity, confirmed structural identification, and the excellent analytical documentation offered by the fournisseur.

• Ingrédient clé et efficacité : Premium Tanshinone IIA is standardized to a excessive purity degree (e.g., 98% or 99%). Its extensively researched pharmacological actions embrace:

  • Cardiovascular Safety: Demonstrates protecting results towards myocardial ischemia, improves microcirculation, and reduces atherosclerosis by inhibiting vascular irritation and easy muscle cell proliferation.

  • Propriétés antioxydantes et anti-inflammatoires : Scavenges free radicals and modulates key inflammatory pathways (e.g., NF-κB), contributing to its total cardioprotective and neuroprotective results.

  • Anticancer Potential: Induces apoptosis and inhibits proliferation and metastasis in varied most cancers cell traces in preclinical research. Observe: Primarily for analysis use.

  • Neuroprotective Results: Reveals promise in defending towards neurodegenerative ailments like Alzheimer’s by lowering oxidative stress and irritation within the mind.

  • (Compliant for analysis functions, pharmaceutical intermediate use, and reference requirements.)

• Origine et haute qualité : Our uncooked materials, Salvia miltiorrhiza root, is sourced from GAP (Good Agricultural Apply) licensed cultivations in areas recognized for top tanshinone content material, guaranteeing a constant and potent beginning materials.

• Utilisation et dosage :

  • Utilisation typique : Predominantly utilized in pharmaceutical R&D as a reference commonplace, a lead compound for novel drug synthesis, and for in vitro and in vivo (animal mannequin) pharmacological research.

  • Posologie bénéfique : There isn’t a established every day consumption for people. All dosing is extremely particular to analysis protocols. Our technical staff supplies information to tell your experimental design.

• Téléspectateurs concernés : Pharmaceutical R&D departments, tutorial analysis establishments, and biotechnology firms engaged in cardiovascular, oncology, and neurology analysis.

• Notes et résultats d'aspect :

  • Précautions: FOR RESEARCH USE ONLY. Not supposed for human consumption as a dietary complement. It’s a potent bioactive compound and ought to be dealt with by certified professionals in laboratory settings.

  • Résultats des aspects : Based mostly on analysis, potential unwanted effects could embrace anticoagulant results and gastrointestinal discomfort at excessive doses.

4. Why Companion with Zhonghong (Aiherba) as Your Tanshinone IIA Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (Publicité mondiale : Aiherba) est une entreprise de haute technologie autorisée et une entreprise de confiance exportateur specializing within the isolation and purification of high-potency, plant-derived energetic compounds for the worldwide B2B marché.

• Excellence scientifique : Our joint laboratories with 5 main universities and portfolio of 20+ patents permit us to grasp complicated purification and crystallization processes, providing Tanshinone IIA of outstanding purity and consistency.

• Une gestion de haute qualité inégalée : Our funding in superior gear like HPLC and Superconducting NMR ensures our purity requirements exceed typical trade specs by 20%, which is vital for reproducible and dependable analysis outcomes.

• Communauté B2B mondiale : Avec 28 ans d'expertise dans les composés bioactifs, nous fournissons personnalisé substances and reference requirements to multinational pharmaceutical firms, de gros distributors, and premier analysis establishments throughout 80+ nations.

• Assistance technique : We offer complete supporting documentation, together with detailed C of A, MSDS, and HPLC/LC-MS chromatograms, that are important on your regulatory compliance and analysis integrity.

5. Spécifications détaillées du produit (COA)

Each batch is accompanied by a complete Certificates of Evaluation (COA) to ensure it meets rigorous research-grade requirements.

6. Cours de fabrication et gestion de la qualité

The isolation of Tanshinone IIA requires refined strategies resulting from its complicated construction and the presence of different related compounds within the plant matrix. We start with the extraction of dried Danshen roots utilizing specialised solvents. The crude extract then undergoes a meticulous multi-step purification course of, which incorporates superior chromatographic separation (e.g., preparative HPLC or column chromatography) to isolate Tanshinone IIA from different tanshinones and salvianolic acids. The ultimate step entails crystallization to acquire the pure, crystalline compound.

Notre Gestion de haute qualité protocol is designed for pharmaceutical-grade actives. It begins with botanical authentication and is adopted by in-process testing at each vital juncture of the extraction and purification course of. Closing product evaluation is paramount. We use Excessive-Efficiency Liquid Chromatography (HPLC) with a diode-array detector (DAD) to exactly quantify the Tanshinone IIA content material and make sure the absence of impurities. Structural affirmation is achieved utilizing Liquid Chromatography-Mass Spectrometry (LC-MS) and Nuclear Magnetic Resonance (NMR) spectroscopy. This multi-layered QC course of, performed in our state-of-the-art labs, ensures each batch delivers constant, dependable efficiency in your most delicate analysis functions, making us a premier extrait naturel personnalisé associate for the pharmaceutical trade.

7. Scénarios d'application

Tanshinone IIA is primarily utilized in superior analysis and growth settings:

• R&D pharmaceutique : As a lead compound in cardiovascular drug discovery, a reference commonplace for high quality management, and for pharmacokinetic and metabolic research.

• Educational Analysis: Utilized in pharmacology and cell biology departments to check mechanisms of cardioprotection, angiogenesis, apoptosis, and irritation.

• Superior Cosmeceuticals: Investigated for its potent antioxidant and anti inflammatory properties in high-end skincare formulations focusing on redness and environmental harm.

8. Analysis, Innovation, and Challenges

The first mechanisms of Tanshinone IIA contain the regulation of calcium channels, inhibition of oxidative stress, and modulation of apoptosis and inflammatory pathways. Present frontières de l'analyse are targeted on bettering its poor aqueous solubility and oral bioavailability by novel drug supply techniques, equivalent to liposomes, nanoparticles, and phospholipid complexes. The primary problème is translating its sturdy in vitro and in vivo efficacy into efficient and protected medical therapies. At Zhonghong, our innovation lies in growing these superior supply techniques and offering our B2B companions with the vital high-purity uncooked supplies wanted for his or her cutting-edge drug growth applications.

9. FAQ – Questions fréquemment posées

Q: What is the Minimal Order Amount (MOQ) for analysis functions?
A: MOQs range based mostly on the purity grade. We accommodate orders for research-scale portions (grams). Contact us to debate your particular wants for en gros or smaller orders.

Q: Are you able to present Tanshinone IIA in numerous salt varieties or solubilized formulations?
R : Bien sûr, nous sommes spécialisés dans extrait naturel personnalisé options. We are able to present the compound as a sodium sulfonate spinoff (extra water-soluble) or focus on co-development of novel formulations for enhanced supply.

Q: Do you supply samples for technique growth and validation?
R : Complètement. Nous offrons extrait naturel de motif gratuit supplies to certified analysis establishments and corporations for analysis and testing functions.

Q: What packaging do you utilize to make sure product stability?
A: We use sealed, amber glass vials or double-layer plastic luggage with desiccant inside foil-lined containers to guard the compound from mild, moisture, and oxygen, guaranteeing stability throughout storage and transit.

Q: What documentation is supplied with worldwide orders?
A: We offer a full suite of paperwork together with Certificates of Evaluation (COA), Materials Security Information Sheet (MSDS), Certificates of Origin, and business bill, guaranteeing easy customs clearance.

10. Où acheter et demander des échantillons gratuits

En tant que numéro un producteur et fournisseur mondial of high-potency plant compounds, we’re your trusted associate for sourcing research-grade Tanshinone IIA.

Contact us right this moment to debate your procurement wants, request a free pattern on your R&D, and get a aggressive wholesale value.

• Courrier électronique : ventes@aiherba.com / liaodaohai@gmail.com

• Site web: www.aiherba.com

11. Conclusion

Pour B2B shoppers in pharmaceutical and superior analysis, Tanshinone IIA represents a robust and well-researched software for cardiovascular and oncology drug discovery. Deciding on a supplier with refined purification capabilities, absolute analytical precision, and a deep understanding of regulatory compliance is paramount. Zhonghong (Aiherba) gives not only a product, however a dependable partnership, offering the high-purity, meticulously documented compounds required to drive innovation in your labs, backed by practically three a long time of experience in bioactive compounds.

12. Références

• Pharmacological Critiques: Complete evaluations on the pharmacology of Tanshinone IIA.

• Acta Pharmacologica Sinica: Key research on the cardiovascular protecting mechanisms of Tanshinone IIA.

• Journal of Ethnopharmacology: Analysis on the standard use and trendy pharmacology of Salvia miltiorrhiza.

• USP-NF Compendial Strategies for analytical testing.