Rhamnose: Premium Manufacturer & Global Supplier for Cosmetic, Pharmaceutical and Food Applications | Aiherba
Source high-purity Rhamnose from Zhonghong, a leading fabricant et fournisseur en vrac. Natural deoxy sugar for skincare, flavors & pharmaceuticals. Demandez un échantillon gratuit et obtenir un prix compétitif prix citation.
1. What is Rhamnose?
Rhamnose (or L-Rhamnose) is a naturally occurring deoxy sugar, specifically a 6-deoxyhexose. It is commonly found in nature as a component of plant glycosides, bacterial polysaccharides, and various bioflavonoids like quercetin and rutin. Unlike many common sugars, its unique structure makes it metabolically stable in many applications, serving as an excellent building block for various compounds. For B2B clients across the cosmetic, flavor & fragrance, pharmaceutical, and food industries, a reliable Rhamnose manufacturer provides a versatile, multifunctional ingredient with diverse applications.
2. Source, propriétés chimiques et identifiants
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Source du produit : Primarily produced through the acid hydrolysis of natural plant-derived glycosides (like rutin from Sophora japonica or quercitrin from quercus species), followed by purification. It can also be produced via microbial fermentation.
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Classification chimique : Deoxy sugar (Methylpentose).
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Numéro CAS : 3615-41-6 (for L-Rhamnose monohydrate)
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Formule moléculaire (MF) : C6H12O5
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Poids moléculaire (PM) : 164.16 g/mol (Anhydrous); 182.17 g/mol (Monohydrate)
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EINECS : 222-793-4
3. What Defines the Best Rhamnose? A B2B Buyer’s Guide
Pour international marques et exportateurs, the “best” Rhamnose is defined by its high purity (anhydrous or monohydrate form), optical purity (L-enantiomer), low color, low residual mineral content, and the supplier’s ability to ensure batch-to-batch consistency.
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Ingrédient clé et efficacité : Premium Rhamnose is a high-purity compound (e.g., ≥98% or USP grade). Its value is derived from its function as a precursor and building block:
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Skin Rejuvenation & Anti-Aging (Cosmetics): Research indicates it can stimulate aquaporin channels in skin cells, improving cellular hydration and potentially promoting the synthesis of collagen and elastin, leading to firmer, more youthful-looking skin.
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Flavor & Fragrance Precursor: Serves as a key starting material for the synthesis of certain high-value flavor compounds.
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Intermédiaire pharmaceutique : Used in the synthesis of certain antibiotics, vitamins (like B2), and other bioactive molecules.
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Sweetness Modifier: Can be used to modify the sweetness profile and mouthfeel in food and beverage applications.
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(Compliant for use in cosmetics, as a food additive (where approved), and as a pharmaceutical intermediate. Regulatory status varies by application and region.)
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Origine et qualité : Our Rhamnose is derived from hydrolyzing high-quality plant glycosides, ensuring a natural origin and a product free from allergens common in other sources.
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Utilisation et dosage :
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Utilisation typique : Incorporated into anti-aging serums, creams, lotions, functional food formulations, and as a raw material for chemical synthesis.
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Posologie recommandée : In cosmetic formulations, effective concentrations typically range from 1% to 5%. Usage levels in other applications are highly specific to the desired outcome.
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Public concerné : Formulators developing high-end anti-aging cosmetics, flavor & fragrance houses, pharmaceutical synthesis departments, and functional food developers.
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Remarques et effets secondaires :
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Précautions: Generally recognized as safe for topical use and as a food component in moderate amounts. It is poorly absorbed in the human intestine.
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Effets secondaires : None known for topical use. Excessive oral consumption may have a laxative effect, similar to other sugars.
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4. Why Partner with Zhonghong (Aiherba) as Your Rhamnose Manufacturer?
Shaanxi Zhonghong Investment Technology Co., Ltd. (Marketing mondial : Aiherba) est une entreprise de haute technologie certifiée et une entreprise de confiance exportateur specializing in the hydrolysis, fermentation, and purification of premium, plant-based ingredients for the global B2B marché.
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Excellence scientifique : Our joint laboratories with 5 leading universities and portfolio of 20+ patents allow us to optimize hydrolysis and purification processes for maximum Rhamnose yield and purity from plant sources.
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Contrôle de qualité inégalé : Our investment in advanced equipment like HPLC and chiral chromatography ensures our product meets high purity specifications and confirms the correct L-enantiomeric form, which is critical for biological activity.
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Réseau B2B mondial : Avec 28 ans d'expérience dans les composés bioactifs, nous fournissons personnalisé ingrédients et de gros quantités aux marques cosmétiques multinationales, de gros distributors, and pharmaceutical companies across 80+ countries.
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Support technique : We provide comprehensive technical dossiers, application guidance, and stability data, making us more than just a fournisseur mais un véritable partenaire d'innovation pour votre extrait de plantes personnalisé and chemical needs.
5. Spécifications détaillées du produit (COA)
Every batch is accompanied by a comprehensive Certificate of Analysis (COA) to guarantee it meets the stringent standards of your industry.
Catégorie | Nom de l'article | Spécification | Méthode d'essai |
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Pureté et identité | Dosage (HPLC) | ≥98,0% | HPLC |
Optical Rotation [α]₂₀D | +7.5° to +9.5° | Polarimétrie | |
Specific Identity (IR) | Conforme à la norme | FT-IR | |
Métaux lourds | Plomb (Pb) | ≤ 2,0 mg/kg | ICP-MS |
Arsenic (As) | ≤ 1,0 mg/kg | ICP-MS | |
Cadmium (Cd) | ≤ 0,5 mg/kg | ICP-MS | |
Mercure (Hg) | ≤ 0,1 mg/kg | ICP-MS | |
Microbiologie | Nombre total de plaques | ≤1000 UFC/g | USP <61> |
Levures et moisissures | ≤100 UFC/g | USP <61> | |
E. Coli | Absent | USP <62> | |
Salmonella | Absent | USP <62> | |
Residuals | Perte au séchage | ≤10.0% (Monohydrate) | USP <731> |
Cendres sulfatées | ≤0,1% | USP <281> |
6. Processus de production et contrôle qualité
Our production of L-Rhamnose typically begins with the extraction of flavonoid glycosides (like rutin) from selected plant sources. The extracted glycosides then undergo a controlled acid hydrolysis process, which selectively cleaves the sugar moieties, releasing Rhamnose. The resulting hydrolysate is then subjected to a meticulous multi-stage purification process. This involves steps like neutralization, filtration, decolorization (using activated carbon), and crystallization to isolate the pure L-Rhamnose, which is then dried and milled to the desired particle size.
Notre Contrôle de qualité is integrated into every step of the manufacturing process. It starts with the authentication and assay of the raw plant material. In-process testing during hydrolysis monitors the reaction completion and helps minimize the formation of degradation products. The final product is rigorously analyzed. Chromatographie liquide à haute performance (HPLC) with a refractive index (RI) or evaporative light scattering (ELSD) detector is the primary method for quantifying the Rhamnose content and assessing purity. Polarimétrie is essential to confirm the specific optical rotation, ensuring the product is the biologically relevant L-enantiomer and not a racemic mixture. Spectroscopie IRTF confirms the identity of the compound. We also employ ICP-MS for sensitive heavy metal detection and standard microbiological testing. This multi-tiered QC protocol guarantees a product that is pure, safe, and consistent for our global clients.
7. Scénarios d'application
Rhamnose is a versatile ingredient for multiple high-value industries:
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Cosmeceuticals & Skincare: The primary application is in high-end anti-aging products, moisturizers, and serums for its purported skin rejuvenation and hydrating properties.
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Flavor & Fragrance Industry: Used as a starting material for the synthesis of certain furanone flavors and fragrance components.
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Médicaments: Employed as a chiral building block and intermediate in the synthesis of various antibiotics, vitamins, and other active pharmaceutical ingredients (APIs).
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Alimentation et boissons : Used as a mild sweetener and texturizer in some specialized food products.
8. Rôle technique, recherche et innovation
Rhamnose’s value lies in its role as a stable, natural chiral building block. Its proposed mechanism in skincare involves the upregulation of aquaporin-3 (AQP3) water channels in the skin, enhancing moisture transport and potentially influencing gene expression for collagen production. Current frontières de la recherche are exploring its use in synthesizing novel glycoconjugates for targeted drug delivery and its prebiotic potential. The main défi and area of innovation is improving the cost-efficiency of its production from sustainable sources and developing new, high-value derivatives. At Zhonghong, our R&D focuses on optimizing our hydrolysis and purification technology to provide our B2B partners with a high-purity, competitively priced product that meets the evolving needs of the market.
9. FAQ – Foire aux questions
Q: What is the difference between L-Rhamnose and D-Rhamnose?
A: They are enantiomers (mirror-image isomers). L-Rhamnose is the naturally occurring and biologically active form used in cosmetics and nutrition. Our product is specifically L-Rhamnose.
Q: Can you provide Rhamnose derived from non-plant sources?
A: Our primary production is plant-based hydrolysis. We also offer Rhamnose produced via microbial fermentation for specific customer requirements. Please inquire for details.
Q: Is your Rhamnose suitable for organic certification?
A: We offer both conventional and organically certified versions (e.g., from organically grown plant sources). Please inquire for specific certification documentation.
Q: Do you offer samples for our product development and testing?
R : Absolument. Nous fournissons échantillon gratuit d'extrait de plantes and chemical materials to qualified businesses for evaluation and application testing in their labs.
Q : Quel emballage utilisez-vous pour l’exportation internationale ?
A: We use sealed, double-layer plastic bags with desiccant inside foil-lined cardboard drums or fiber drums to protect the product from moisture during transit.
10. Où acheter et demander des échantillons gratuits
En tant que leader fabricant et fournisseur mondial of premium sugars and plant actives, we are your trusted partner for sourcing high-quality L-Rhamnose.
Contactez-nous dès aujourd'hui pour discuter de vos besoins d'approvisionnement, demander un échantillon gratuit pour votre R&D et obtenir un prix de gros compétitif.
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E-mail: ventes@aiherba.com / liaodaohai@gmail.com
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Site web: www.aiherba.com
11. Conclusion
Pour B2B clients in the cosmetic, pharmaceutical, and food industries, L-Rhamnose offers a unique, multifunctional natural building block. Choosing a supplier with robust production technology, rigorous QC that includes chiral purity confirmation, and global exporter capabilities is crucial for product quality and supply chain reliability. Zhonghong (Aiherba) provides not just a product, but a reliable partnership, offering a premium, well-documented ingredient that will empower your innovative formulations, backed by nearly three decades of experience.
12. Références
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Carbohydrate Research: Studies on the properties, synthesis, and occurrence of L-Rhamnose.
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International Journal of Cosmetic Science: Research on the effects of Rhamnose on skin hydration and gene expression.
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USP/EP/JP Monographs for analytical standards (where applicable).
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ICH Guidelines for impurities in new drug substances (Q3A) when used as a pharmaceutical intermediate.
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