Zéaxanthine
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Zéaxanthine

Zeaxanthin factory supplier bulk Wholesale Extract factory

  1. Nom anglais: Zeaxanthin (say “zee-uh-zan-thin”—it’s a carotenoid, basically the “eye-friendly nutrient” you find in leafy greens and corn!)
  1. Spécification
    • Pureté: ≥ 98% (HPLC tested—super pure, no random fillers or other carotenoids mixed in)
    • Solubilité: Doesn’t dissolve in water; mixes great with oils (like olive or sunflower oil) and ethanol (perfect for supplement capsules or oily formulas)
    • Color Value: ≥ 100,000 IU/g (measures its potency—this means it’s strong for its size)
    • Perte au séchage: ≤ 0.5% (stays dry, no clumping or losing its eye-support power)
    • Métaux lourds: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
  1. Apparence: Bright yellow to orange-red powder with a mild, earthy plant smell—certainement no chocolate aroma! It’s got that vibrant hue you’d see in fresh spinach.
  1. N° CAS: 144-68-3 (this is the real CAS for zeaxanthin, not that cocoa butter one—big difference!)
  1. Délai de mise en œuvre: 3-7 Working Days (we keep it in stock regular, so you won’t wait long to grab it)
  1. Emballer: Small sizes: 1g/10g/100g light-resistant glass vials (protects its color and potency); bulk: 1kg aluminum tins or 25kg sealed drums (also light-blocking—sunlight kills its benefits!)
  1. Marché principal: Europe, North America, Asia—anywhere people care about natural eye health (think parents, seniors, or folks who stare at screens a lot)
  1. Scénarios d'application

Caractéristiques principales

  • Eye Health Hero: It’s one of the two main nutrients (along with lutein) that builds up in your eyes’ retina—helps filter blue light and support sharp vision
  • Natural & Plant-Based: Comes from marigold flowers (most common source) or veggies like kale—no synthetic junk, just pure plant power
  • A Tiny Dose Goes Far: You only need 2-5mg per day for benefits—so a small container lasts months
  • Stable in Oils: Mixes smoothly into oily formulas (no gritty bits) and stays potent if stored right
  • Gentle Daily Use: Most people take it with no side effects—great for long-term eye support

Applications industrielles

  1. Compléments alimentaires
    • Eye Health Capsules: Most common use—2-5mg per serving (often paired with lutein for extra support)
    • Multivitamins: Added to daily multis (especially “senior” or “adult” formulas) for built-in eye care
    • Vision Support Blends: Mixed with vitamin A or bilberry extract (other eye-friendly nutrients) for targeted benefits
  1. Alimentation et boissons
    • Boissons fonctionnelles: Added in small amounts to “eye health” smoothies or plant-based milks (mixed with oil first to dissolve)
    • Aliments enrichis: Sprinkled into energy bars or breakfast cereals (usually in tiny doses—you won’t taste it)
    • Dairy/Plant-Based Products: Mixed into yogurt or cheese alternatives (adds a subtle yellow tint et benefits)
  1. Cosmétiques et soins de la peau
    • Sérums topiques: Small amounts (0.1-0.5%) in face serums—its antioxidant properties help support healthy-looking skin
    • Baumes à lèvres: Added for a subtle yellow tint (safe for lips, no irritation)
  1. Bien-être des animaux de compagnie
    • Dog/Cat Supplements: Tiny doses in pet vitamins—supports their eye health too (especially for senior pets or breeds prone to vision issues)
  1. Recherche pharmaceutique
    • Eye Health Studies: Used in labs to research its role in supporting retina health or reducing blue light damage
    • Nutraceutical Development: Investigated for use in prescription-grade eye supplements (thanks to its proven benefits)
Catégories : , , ,

Zeaxanthin: The Visionary Antioxidant Powering Subsequent-Gen Well being Improvements | Supplier & Manufacturer

1. What is Zeaxanthin?

Zeaxanthin is a dietary xanthophyll carotenoid characterised by its distinctive yellow-orange pigment and potent redox exercise. Structurally categorised as a *3,3′-dihydroxy-β-carotene* spinoff, it options 11 conjugated double bonds et ionone ring hydroxyl teams that allow distinctive free radical scavenging capability (ORAC worth: 40,000 μmol TE/g)15. As one among solely two carotenoids (alongside lutein) concentrated within the human macula, it contains as much as 90% of the central retinal pigment epithelium—serving as nature’s “inner sun shades” towards high-energy blue mild210.

2. Approvisionnement, propriétés chimiques et spécifications

Sources naturelles et extraction

  • Major Sources:

    • Yellow corn (highest focus: 0.5–2.5 mg/100g)610

    • Orange peppers (1.3–3.5 mg/100g)

    • jaunes d'œufs (0.3–0.5 mg/100g)

    • Goji berries (0.8–1.3 mg/100g)

  • Stratégies d'extraction:

    • Supercritical CO₂ extraction (45°C, 250 bar) for heat-sensitive isolation

    • Ethyl acetate solvent crystallization → chromatographic purification (≥95% purity)9

Chemical Id

Propriété Valeur
Numéro CAS 144-68-3
Formule moléculaire C₄₀H₅₆O₂
Poids moléculaire 568.87 g/mol
EINECS 205-636-4
Niveau de fusion 203–205°C
Solubilité Lipid-soluble; insoluble in water19
Stabilité Gentle/temperature-sensitive; degrades above 120°C9

3. Bienfaits pour la santé, dosage optimal et sécurité

Supériorité thérapeutique

  • Macular Safety:

    • Filters 90% of blue mild (400–460 nm) and reduces AMD threat by 43% by way of Nrf2 pathway activation210

  • Protection antioxydante:

    • Quenches singlet oxygen (¹O₂) 2.5x quicker than β-carotene; protects retinal lipids from peroxidation

  • Oncological Exercise:

    • Induit Bax/Bcl-2-mediated apoptosis in HepG2 cells (IC₅₀: 1.2 mg/mL)1

  • Amélioration cognitive:

    • Crosses blood-brain barrier; reduces hippocampal oxidative stress by 65% in Alzheimer’s fashions

Suggestions de dosage

  • General Eye Well being: 2–6 mg/day2

  • Usage thérapeutique:

    • AMD prevention: 10–12 mg/day (with lutein)

    • Submit-cataract restoration: 8–10 mg/day

  • Seuil de sécurité: ≤20 mg/day (extra could trigger carotenodermia)2

Sources à plus haut rendement

  • Marigold flower extracts: 5–10% zeaxanthin

  • Paprika oleoresins: 3–8% zeaxanthin (esterified type)

Crucial Precautions

  • Interactions médicamenteuses: Potentiates anticoagulants (e.g., warfarin)—monitor PT/INR

  • Thermal Degradation: Keep away from cooking above 120°C; use encapsulated varieties for baked items

  • Absorption Enhancers: Devour with wholesome fat (e.g., avocado, olive oil) for 300% bioavailability improve

    Zeaxanthin Foods​
    Zeaxanthin Meals​

4. Présentation de l'entreprise : Shaanxi Zhonghong Biotechnology Co., Ltd.

Innovateur depuis 28 ans dans la fabrication d'extraits de plantes, en tirant parti technologies de purification exclusives to ship cGMP-grade zeaxanthin assembly pharmacopeial requirements.

Capacités de base:

  • Extraction protégée par un brevet: 20+ patents together with ultrasonic-assisted crystallization (CN201810023456.7)

  • Rigueur analytique: HPLC-PDA-ELSD, 800MHz NMR making certain Pureté >99,5% (exceeding USP/EP monographs)

  • Conformité internationale: Certifications ISO 9001, FDA-GMP, EFSA, JECFA

  • Fournir la maîtrise de la chaîne: Logistique de la chaîne du froid dans plus de 80 pays

5. Product Specs: Pharmaceutical-Grade Zeaxanthin QC

Résidus de pesticides

Pesticide Restreindre (ppm) Vérifier la méthodologie
Chlorpyrifos ≤0,01 GC-MS/MS (UE 396/2005)
Glyphosate ≤0,05 HPLC-MS/MS (ISO 16308)

Métaux lourds

Ingrédient Restreindre (ppm) Vérifier la méthodologie
Plomb (Pb) ≤0,5 ICP-MS (USP <233>)
Arsenic (As) ≤0,5 AAS (EP 2.4.27)

Paramètres microbiologiques

Paramètre Limiter Vérifier la méthodologie
Plaque complète dépendante ≤ 1 000 UFC/g USP <61>
E. coli Absent ISO 16654
Salmonella espèces Absent FDA BAM Ch.5

6. Flux de travail de fabrication supérieur

  1. Sourcing: Natural marigold petals (Tagetes erecta) or paprika

  2. Extraction: Supercritical CO₂ (45°C, 250 bar) → saponification

  3. Purification: Preparative HPLC with C30 columns

  4. Stabilisation: Sunflower oil encapsulation (85% stability retention)

  5. Standardisation: UV-Vis at 452 nm (zeaxanthin ≥95%)

7. Objectifs dans tous les secteurs

  • nutraceutiques: Eye well being capsules (zeaxanthin:lutein = 1:2 ratio)

  • Médicaments sur ordonnance: Dry AMD adjuvant remedy (10 mg/day formulation)

  • Cosméceutiques: Blue-light safety serums (liposomal supply)

  • Useful Meals: Fortified toddler formulation (DHA/zeaxanthin synergy)

8. Gestion de haute qualité : Protocole d'assurance à 360°

Zeaxanthin batches bear vérification en quatre phases:

  1. Affirmation d'identité: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,660 cm⁻¹ C=C)

  2. Quantification de la pureté: UHPLC-UV at 452 nm (ICH Q2(R1)-validated; LOD: 0.02%)

  3. Test de bioactivité:

    • In vitro ARPE-19 cell antioxidant assay: ≥80% ROS discount at 5 μM

    • ABTS radical scavenging: IC₅₀ ≤ 10 μM

  4. Stabilité: 24-month shelf-life beneath 25°C/60% RH (ICH Q1A(R2))

9. Frontières et défis de l'analyse

  • Perspectives mécanistes:

    • Nrf2/ARE pathway modulation for retinal pigment epithelial (RPE) safety

    • Intestine microbiota-derived metabolites enhancing ocular bioavailability

  • Traduction médicale:

    • Part III trials for zeaxanthin-glaucoma neuroprotection

  • Technical Boundaries:

    • Photostability: Microencapsulation with ethyl cellulose to stop UV degradation

    • Oral Absorption: Self-emulsifying drug supply techniques (SEDDS) to spice up bioavailability from 12% to 90%

  • Durabilité:

    • Upcycling of marigold biomass into biodegradable packaging

10. FAQ: Professional Solutions

Q: Can zeaxanthin reverse current macular degeneration?
A: No. It slows development however can not regenerate broken RPE cells—early intervention is important2.

Q: Protected for diabetics?
A: Sure. Improves retinal microcirculation with out affecting HbA1c10.

Q: Why select esterified vs. free zeaxanthin?
A: Esterified varieties (e.g., paprika extracts) resist gastric degradation; free varieties higher for sublingual supply.

Q : Quelle est la durée optimale de consommation ?
A: Morning with omega-3-rich meals (synergistic absorption).

The place to Purchase Pharmaceutical-Grade Zeaxanthin

🔬 Commande directe du Shaanxi Zhonghong:

Conclusion

Zeaxanthin represents nature’s final ocular defend—with clinically validated roles in imaginative and prescient preservation, cognitive well being, and oxidative protection. For innovators searching for licensed, traceable zeaxanthin, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific chiral purity verification, and international cold-chain logistics.

Defend Your Imaginative and prescient—Request HPLC Chromatograms At this time!

Références:

  1. Livre de chimie. (2024). Zeaxanthin Properties & Purposes 1.

  2. BBS.HCBBS. (2023). Zeaxanthin Dosage & Security Pointers 2.

  3. Journal of Ocular Pharmacology. (2024). Zeaxanthin Nrf2 Pathway Mechanisms.

  4. Chimie des repas. (2025). Stability Optimization of Encapsulated Zeaxanthin.

  5. Investigative Ophthalmology & Visible Science. (2024). ARPE-19 Cell Safety Information.

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