Poudre de collagène de poisson pur

Pure Fish Collagen Powder: Premium Marine Sourcing from Zhonghong Biotech (Free Samples Available)

1. What is Pure Fish Collagen Powder?
Pure Fish Collagen Powder, predominantly Type I collagen, is a hydrolyzed protein derived from the skin, scales, and bones of marine fish (e.g., Tilapia, Cod). This enzymatic hydrolysis process yields bioactive peptides de collagène – low molecular weight fragments (typically 2,000-5,000 Da) with significantly enhanced biodisponibilité compared to native collagen. These peptides are rapidly absorbed into the bloodstream via the paracellular pathway et PepT1 transporter, facilitating targeted delivery to skin, joints, and connective tissues to stimulate endogenous collagen synthesis via fibroblast activation and modulation of TGF-β/Smad signaling pathways. Its superior solubility, neutral taste, and odorless profile make it ideal for nutraceutical and functional food applications.

2. Source du produit, propriétés chimiques et identification

• Source: Sustainably sourced Marine Fish (Tilapia nilotica, Gadus morhua). Traceability protocols ensure origin compliance.

• Numéro CAS : 9007-34-5

• Formule moléculaire (MF) : Represents repeating amino acid sequences (primarily Gly-X-Y, where X & Y are often Pro and Hyp).

• Poids moléculaire (PM) : Hydrolyzed form: Typically 2,000 – 5,000 Daltons (Da).

• EINECS : 232-697-4

• Principales propriétés chimiques : High solubility (><｜begin▁of▁thinking｜> pH stability, rich in Glycine (~33%), Proline (~12%), Hydroxyproline (~10%) – crucial for triple-helix stability and biological activity. Exhibits characteristic FT-IR spectra (Amide I, II, III bands) and DSC thermograms.

3. Why Zhonghong Biotech’s Pure Fish Collagen is the Optimal Choice
Zhonghong Biotech sets the benchmark for premium Pure Fish Collagen Powder through rigorous science and quality:

• Premium Ingredients: 100% pure hydrolyzed fish collagen peptides. Non-GMO, Gluten-Free, Allergen-Free (BSE/TSE Free). No fillers or artificial additives.

• Clinically Validated Efficacy (Compliant): Supports skin dermal matrix integrity (increases elasticity, reduces wrinkles – in vivo studies), promotes chondrocyte proliferation et synovial fluid viscosity for joint comfort, enhances bone mineral density (Osteoblast stimulation), aids muscle protein synthesis (MPS), and supports gut mucosal barrier function.

• Optimal Daily Intake: Recommended dosage: 5g to 10g daily. Efficacy supported by clinical research (e.g., Proksch et al., 2014). Consult a physician for specific needs.

• Origine et fabrication : Sourced responsibly, processed in cGMP-certified facilities in China. Advanced enzymatic hydrolysis ensures optimal peptide profile.

• Usage: Easily soluble in hot/cold beverages, smoothies, yogurts, or baked goods. Ideal for capsules, tablets, and functional foods.

• Public cible : Adults seeking skin health, joint support, athletes, seniors, individuals in wellness programs.

• Sécurité et effets secondaires : Generally Recognized As Safe (GRAS). Well-tolerated. Potential mild gastrointestinal discomfort if taken in excessive doses initially.

• Considérations critiques : Verify Allergen Statements (fish source), ensure product has full Certificat d'analyse (CoA) confirming purity and safety (see below). Contraindicated for individuals with severe fish allergies.

4. Zhonghong Biotech: Your Trusted Collagen Partner
Zhonghong Biotech (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a globally recognized leader in the research, development, and large-scale manufacturing (Bulk Supplier) of high-purity bioactive compounds. With 28 ans of expertise in extraction végétale et marine bioactives, we serve the chemical, material science, and life science sectors.

• Prouesses scientifiques : Collaboration with 5 universités d'élite fuels our Plus de 20 technologies brevetées and exclusive bibliothèque mondiale de composés, creating significant R&D barriers.

• Infrastructure de pointe : Équipé de HPLC (Chromatographie liquide haute performance), UHPLC-MS (Ultra-HPLC-Mass Spectrometry), et 600MHz Superconducting NMR (Nuclear Magnetic Resonance). Our purity standards exceed industry norms by 20%+.

• Global Supply Chain Excellence: Our robust network delivers extrait de plantes personnalisé and bioactive solutions to plus de 80 pays, serving multinational pharmaceutical companies, leading nutraceutical brands (De gros partners), and premier research institutions. We specialize in solutions personnalisées tailored to specific application requirements.

5. Comprehensive Product Specifications & Certificate of Analysis (CoA)
Zhonghong guarantees transparency. Every batch undergoes stringent testing per international pharmacopeia (USP, EP).

Pure Fish Collagen Powder – Certificate of Analysis (CoA) Summary

6. Advanced Production Process: Precision Hydrolysis
Our optimized manufacturing ensures peak bioactivity:

1. Sustainable Sourcing & Prep: Raw fish by-products undergo rigorous veterinary inspection and controlled trimming/washing.

2. Demineralization & Defatting: Acid/alkali treatment removes minerals and lipids.

3. Enzymatic Hydrolysis: Specific proteolytic enzymes (e.g., Alcalase, Trypsin) cleave collagen under controlled T/pH/duration to yield target peptide profiles (<5kDa).

4. Purification en plusieurs étapes : Filtration (ultrafiltration/nanofiltration), ion-exchange, and activated carbon remove impurities, odors, and salts.

5. Stérilisation et séchage : Terminal sterilization (where applicable) followed by séchage par atomisation (inlet/outlet temp control) or lyophilisation for maximum stability.

6. Strict QC Release: Comprehensive testing per CoA specifications before packaging.

7. Divers scénarios d'application

• Nutraceutiques : Capsules, tablets, stick packs, gummies for skin beauty, joint health, sports nutrition.

• Aliments et boissons fonctionnels : Fortified protein drinks, dairy products, health bars, confectionery.

• Cosméceutiques : Key active in anti-aging serums, creams, masks for dermal rejuvenation et moisture retention.

• Medical Nutrition: Supports tissue repair and wound healing formulations.

• Pet Nutrition: Joint and coat health supplements.

8. Rigorous Quality Control (QC) Protocol
Zhonghong’s QC is integrated throughout the product lifecycle. Starting from Conforme aux BPF raw material qualification (vendor audits, CoA review), we implement Technologie d'analyse des procédés (PAT) for real-time monitoring of critical parameters (pH, temp, peptide size via GPC/SEC) during hydrolysis. Our state-of-the-art Quality Control Laboratory, équipé de HPLC-DAD/ELSD/RID, ICP-MS, GC-MS/MS, UHPLC-QTOF-MS, et Microbiological suites, performs identity, purity, potency, and safety testing per validated methods aligned with ICH Q2(R1). Stability studies (ICH Q1A) ensure shelf-life. Batch traceability is enforced. Our ISO 9001:2015 et ISO 22000/FSSC 22000 certified systems guarantee consistent, safe, high-quality Poudre de collagène de poisson pur meeting global regulatory standards (FDA, EFSA, Health Canada).

9. Emballage sécurisé et logistique mondiale

• Conditionnement: Available in multi-layer foil bags (1kg, 5kg, 10kg) with desiccant, inside food-grade fûts en PEHD (25kg) or fûts en fibre (20kg). Custom packaging for en gros orders. Nitrogen flushing optional.

• Stockage: Store in a cool (<25°C), dry place. Shelf life: 24 months unopened.

• Logistique: Efficient global shipping via air/sea freight. Expertise in export documentation and cold chain (if required). Compliant with IATA/IMDG regulations.

10. Plongée en profondeur : mécanismes de santé, applications et innovation

• Mécanismes de santé : Bioactive peptides (e.g., Pro-Hyp, Gly-Pro-Hyp) act as ligands for receptors on fibroblasts/chondrocytes, stimulating collagen I/III, elastin, et hyaluronic acid synthesis via MAPK/ERK et PI3K/Akt pathways. Exhibit antioxydant activity (radical scavenging), Inhibition des MMP, and modulate inflammatory cytokines (e.g., TNF-α, IL-1β).

• Applications industrielles : Driving innovation in beauty-from-within supplements, osteoarthritis management, sarcopenia mitigation, wound healing biomaterials, et functional food fortification.

• Research & Challenges: Current focus on structure-activity relationship (SAR) of specific peptides, amélioration de la biodisponibilité (nano-delivery), sustainable sourcing (by-product valorization), and clinical validation for new indications (gut-brain axis, metabolic health). Challenges include standardization of bioactive peptide profiles and large-scale cost-effective production of specific sequences.

11. Foire aux questions (FAQ)
Q1: What makes marine collagen better than bovine/porcine?
A1: Marine collagen (Type I) boasts superior biodisponibilité due to lower molecular weight peptides and is preferred for ethical/religious (halal/kosher potential) and safety (BSE-free) reasons. Often perceived as more sustainable.
Q2: How long to see results?
A2: Clinical studies show visible skin improvements (hydration, elasticity) often within 4 à 8 semaines of consistent use (5-10g/day). Joint benefits may take 8 à 12 semaines.
Q3: Is it safe during pregnancy/breastfeeding?
A3: Generally safe, but consult your physician before starting any new supplement.
Q4: Can vegetarians/vegans use this?
A4: No, as it’s derived from fish. Plant-based collagen boosters exist but do not provide direct collagen peptides.
Q5: Do you offer free samples?
A5: Yes! We provide échantillon gratuit d'extrait de plantes of our Pure Fish Collagen Powder for qualified businesses. Contact us to request.
Q6: What customization options are available?
A6: Nous offrons extrait de plantes personnalisé solutions including specific peptide profiles (molecular weight distribution), flavor masking, instantization, and blends with other actives (e.g., Vitamin C, Hyaluronic Acid). Discuss your customized needs.
Q7: What is the minimum order quantity (MOQ)?
A7: Competitive MOQs for en gros et de gros quantities. Contact sales for specific details based on your requirements.
Q8: Where can I buy?
A8: Contact Zhonghong Biotech directly for en gros, de gros, et OEM inquiries. Visit our website for more information.

12. Where to Buy & Request Free Samples
Ready to source premium Poudre de collagène de poisson pur? As a leading fabricant et fournisseur, Zhonghong Biotech offers competitive prix pour en gros quantities and de gros partnerships.

• Get Your Free Sample: Experience the Zhonghong quality difference. Qualified businesses can request échantillon gratuit d'extrait de plantes.

• Contactez-nous:

  • E-mail: ventes@aiherba.com, liaodaohai@gmail.com

  • Site web: www.aiherba.com

  • Objectif de l'enquête : Bulk Orders, Wholesale Pricing, Customization, Free Samples, OEM/ODM Services.

13. Conclusion
Poudre de collagène de poisson pur represents a scientifically substantiated bioactive ingredient for enhancing skin, joint, and overall connective tissue health. Zhonghong Biotech leviers 28 ans of expertise in bioactive extraction and purification, cutting-edge analytical technology (HPLC, NMR, MS), and a global distribution network to deliver a premium, high-purity, traceable marine collagen peptide product. Our commitment to quality control exceeding industry standards, personnalisation capabilities, and provision of échantillons gratuits establishes us as the trusted partner for nutraceutical brands, functional food developers, and de gros distributors worldwide. Contact us today to discuss your collagen sourcing needs and explore partnership opportunities.

14. Références

1. Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. Pharmacologie et physiologie de la peau, 27(1), 47-55.

2. León-López, A., et al. (2019). Hydrolyzed Collagen—Sources and Applications. Molécules, 24(22), 4031.

3. Khatri, M., et al. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino Acids, 53(10), 1493-1506.

4. Song, H., et al. (2022). Bioactive collagen peptides: a review of their generation, bioactivities and applications. Journal des aliments fonctionnels, 88, 104909.

5. ISO 3496:1994. Animal and vegetable fats and oils — Determination of hydroxyproline content.

6. USP-NF General Chapters: <61> Microbiological Examination, <232> Elemental Impurities, <561> Articles of Botanical Origin, <197> Spectrophotometric Identification Tests.

7. European Pharmacopoeia (Ph. Eur.) Monographs and General Chapters (e.g., 2.4.8 Heavy metals, 2.6.12/13 Microbiological examination).