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Rébaudioside A

Rebaudioside A supplier bulk factory Wholesale buy Extract factory

1.Nom anglais: Rebaudioside A

  1. Spécification
    • Pureté: Rebaudioside A ≥ 95% (HPLC); Excessif – purity grade: ≥ 98% (HPLC)
    • Particule Mesures: Normale powder ≤ 100 μm; Micronized powder ≤ 5 μm for enhanced dissolution
    • Solubilité: Soluble in water (5 – 10 g/L at 25°C), ethanol; water – soluble formulations optimized for beverage fonctions
  2. Apparence
    • Powder: White to off – white haute qualité powder, odorless, intensely bonbons style
  3. N° CAS:58543-16-1
  4. Délai de mise en œuvre: 3 à 7 jours ouvrables
  5. Emballer
    • 1 kg/sac (sac en aluminium), 25 kg/fût (sac PE double couche à l'intérieur d'un fût en carton)
  6. Marché principal: North America, Europe, Asia, South America (particulièrement in low – calorie repas and beverage industries)
  7. Scénarios d'application

Propriétés de base

  • Moléculaire Méthode: C₄₄H₇₀O₂₂
  • Style Profile: 200 – 400 cas sweeter than sucrose with minimal bitter aftertaste (en comparaison avec différent steviol glycosides)
  • Clé Options
    • Low – Calorie Sweetener: Zero – calorie divers to sugar, approprié for diabetic and weight – administration diets.
    • Thermostability: Sécurisé ci-dessous excessif temperatures (autant que 120°C), enabling use in baked articles and processed repas.
    • Stabilité du pH: Séjours sécurisé tout au long de pH 3 – 9, splendide pour boissons and acidic marchandises.
    • Origine naturelle:Extrait de Stevia rebaudiana leaves, assemblyclair étiquette" client appelle à.

Scénarios d'application

1. Repas & Boissons

  • Boissons:
    • Ajouté à délicat drinks, juices, teas, and pouvoir drinks at 0.01 – 0.1% se concentrer to exchange ou réduire sucre contenu.
    • Utilisé dans activités sportives boissons offrir douceur sans énergie, soutenir electrolyte stabilité.
  • Bakery & Confectionery:
    • Incorporate into truffes, cookies, and candies, soutenir texture and shelf – life alors que en baisse sugar by 30 – 50%.
    • Perfect for sugar – free chocolate marchandises, enhancing sweetness sans affecting melting properties.
  • Dairy Marchandises:
    • Fortify yogurt, ice cream, and milkshakes, intéressant à bien-êtretrès conscient acheteurs looking for low – calorie choix.

2. Diététique Compléments alimentaires

  • Poids Administration Formulation:
    • Capsules or powders containing Rebaudioside A mixte with fiber and probiotics, marketed for envie de nourriture suppression and calorie rabais.
  • Diabetic – Agréable Compléments alimentaires:
    • Included in glucose – gestion compléments alimentaires, offre douceur sans elevating glycémie gammes.

3. Cosmétiques et Privé Soins

  • Soins bucco-dentaires:
    • Added to toothpaste, mouthwash, and chewing gum offrir douceur alors que en baisse sugar – associé dental points.
  • Soins de la peau:
    • Utilisé dans lip balms and moisturizers for a bonbons goût sans la chance of attracting bugs (not like sugar – principalement basé sweeteners).

4. Alimentation animale

  • Animal de compagnie Repas:
    • Incorporate into pet treats and kibble pour stimuler palatability sans y compris énergie, utile pour chubby pets.
  • Aliments pour le bétail:
    • Utilisé dans poultry and swine feed pour améliorer feed consommation, sans aucun doute croissance développement efficacité.

Détection Stratégies

  • ExcessifEfficacité Chromatographie liquide (HPLC):
    • Colonne : C18 (250 × 4,6 mm, 5 μm), Cellule Partie: Acetonitrile – water (gradient elution), Flux Charge: 1.0 mL/min, Detection Wavelength: 210 nm.
  • ExtrêmementEfficacité Liquid Chromatography – Mass Spectrometry (UPLC – MS):
    • Confirms molecular construction and detects indice impurities, s'assurer excessif – purity exigences.
  • Refractive Index Detection (RID):
    • Used for quantifying Rebaudioside A in compliqué mixtures, offre correct se concentrer information.

Fournir & Avantages

  • Naturel Fournir:Extrait des feuilles de Stevia rebaudiana, a plant native to South America and now cultivated globally.
  • Durabilité: Renewable crop with low water nécessités, supporting eco – agréable fabrication.
  • PrixEfficacité: Réduit longuepériode de temps soins de santé prix lié à sugar – associé maladies (e.g., diabetes) via calorie rabais.

Conformité réglementaire

  • FDA américaine: Typiquement Reconnu Comme Protégé (GRAS) for repas use since 2008, permettant inclusion in varié repas cours.
  • Règlement de l'UE: Permitted en tant que repas additive (E960) with particulier utilisation limits in numerous marchandises.
  • NMPA de Chine: Permitted as a sweetener in repas et boissons, sujet à nationwide sécurité exigences.

Rebaudioside A: The Premium Natural Sweetener Powering More healthy Formulations| Supplier & Manufacturer

1. What is Rebaudioside A?

Rebaudioside A (Reb A) is a extremely prized steviol glycoside, the first sweet-tasting compound remoted from the leaves of the Stevia rebaudiana Bertoni plant. Famend for its distinctive sweetness depth (roughly 200-400 instances sweeter than sucrose) and superior sensory profile in comparison with different steviol glycosides, Reb A delivers a clear, sugar-like style with considerably decreased bitterness and lingering aftertaste. Its zero-calorie, zero-glycemic index nature makes it a cornerstone ingredient within the world shift in the direction of pure, health-conscious sugar discount methods throughout meals, beverage, and nutraceutical industries.

2. Approvisionnement du produit, propriétés chimiques et identifiants clés

  • Fournir: Extracted and purified from the leaves of the Stevia rebaudiana Bertoni plant, native to South America and now cultivated globally.

  • Propriétés chimiques :

    • Sort: Diterpene glycoside.

    • Composants moléculaires : C₄₄H₇₀O₂₃

    • Poids moléculaire : 967.03 g/mol

    • Quantité CAS : 58543-16-1

    • Quantité EINECS : 261-342-2

    • Apparence: Usually a positive, white to off-white crystalline powder.

    • Solubilité: Extremely soluble in water and ethanol.

    • Stabilité: Steady beneath excessive temperatures (baking, pasteurization) and throughout a large pH vary, making it extremely versatile for processing.

3. Why Rebaudioside A is the Finest & Its Well being Profile

  • “The Finest” & Highest Purity: Amongst steviol glycosides, Rebaudioside A (Reb A) is broadly thought to be having essentially the most favorable sensory profile, characterised by its clear sweetness onset and minimal bitterness/licorice aftertaste. Merchandise labeled “Excessive-Purity Reb A” (e.g., 95%, 97%, 98%+) comprise the best focus of this fascinating glycoside, providing superior style efficiency. Reb M can also be famous for a clear profile however is much less considerable naturally and sometimes extra expensive to provide at excessive purity.

  • Well being Benefits & Efficacy:

    • Zero Energy & Zero Glycemic Influence: Essential for weight administration and blood sugar management, notably helpful for diabetics and prediabetics.

    • Dental Well being: Non-cariogenic – doesn’t promote tooth decay.

    • Propriétés antioxydantes : Some analysis suggests steviol glycosides possess gentle antioxidant exercise.

    • Blood Stress Help: Restricted research point out potential gentle vasodilatory results, although extra analysis is required for conclusive well being claims.

  • Day by day Consumption & ADI: The Acceptable Day by day Consumption (ADI) for steviol glycosides (expressed as steviol equivalents) established by JECFA (FAO/WHO) and EFSA is 4 mg per kg of physique weight per day. For a 70kg grownup, this equates to roughly 280 mg of steviol equivalents. Excessive-purity Reb A merchandise sometimes specify their Reb A content material and steviol equal conversion issue.

  • Résultats de sécurité et de facettes : Rebaudioside A is Usually Acknowledged As Protected (GRAS) by the US FDA and accredited for meals use globally (EU, JECFA, and so on.). In depth security evaluations assist its use. Potential unintended effects are uncommon however might embrace gentle gastrointestinal discomfort (bloating, nausea) in delicate people when consumed in very massive portions, considerably exceeding the ADI. No important allergenic potential is thought.

  • Précautions: Whereas secure for the overall inhabitants, people with extreme kidney illness ought to seek the advice of a physician. At all times adhere to beneficial utilization ranges in formulations.

4. Introducing Shaanxi Zhonghong Investment Technology Co., Ltd.: Your Trusted Supply for Premium Reb A
Shaanxi Zhonghong Investment Technology Co., Ltd. stands as a frontrunner within the composés bioactifs business, leveraging 28 ans d'expérience. As a vertically built-in entreprise de haute technologie, we concentrate on agile R&D, built-in manufacturing, and world distribution, serving the demanding wants of the chemical, supplies, and life science sectors. Our core competency lies within the superior extraction, isolation, and purification of high-value plant constituents, together with premium-grade Rebaudioside A.

  • Unmatched Scientific Prowess: We keep strategic collaborations with 5 top-tier universities par le biais de laboratoires d'analyse communs, driving innovation. Our technological edge is protected by over 20 patents and consists of entry to a proprietary world compound library.

  • Chopping-Edge High quality Infrastructure: Our dedication to purity is enforced by instrumentation analytique de pointe, avec Excessive-Efficiency Liquid Chromatography (HPLC), Extremely-Excessive-Efficiency Liquid Chromatography (UHPLC), and Superconducting Nuclear Magnetic Resonance (NMR) spectrometers. This allows us to constantly obtain purity requirements exceeding business norms by 20% or extra.

  • Excellence de la chaîne d'approvisionnement internationale : We possess a strong worldwide distribution community couvrant Asia, Europe, and the Americas (80+ international locations), offrant custom-made ingredient options to multinational pharmaceutical firms, analysis establishments, and premium nutraceutical/meals producers.

5. Rebaudioside A Benefits: Past Sweetness

  • Well being & Wellness: Allows important sugar discount with out sacrificing sweetness, supporting calorie management, blood sugar administration, and dental well being.

  • Clear Label Attraction: A pure, plant-derived ingredient extremely wanted by customers demanding transparency.

  • Formulation Versatility: Distinctive stability beneath warmth and throughout pH ranges permits use in drinks, baked items, dairy, confectionery, and tabletop sweeteners.

  • Value-Effectiveness: Excessive sweetness efficiency means very low utilization ranges are required, typically making it economically viable regardless of the next per-kg worth than sugar.

6. Utilizing Rebaudioside A: Tips

  • Utilization Ranges: Extremely potent; typical utilization ranges vary from 0.01% to 0.05% in drinks and meals, relying on the goal sweetness and the particular product matrix. Alternative ranges for sucrose differ considerably.

  • Synergies : Usually blended with different sweeteners (e.g., erythritol, allulose, monk fruit extract) or flavors to optimize style profile, masks any slight aftertaste, and supply bulk.

  • Application: Simply integrated into each aqueous and lipid-based techniques. Pre-dissolving in water or a water-miscible solvent is widespread for uniform distribution.

7. Product Specs: Rigorous High quality Assurance
Shaanxi Zhonghong ensures Reb A gathering the best worldwide requirements. Our specs embrace complete testing for purity, residues, heavy metals, and microbiology:

Desk 1: Pesticide Residue Limits

Pesticide Residue Venture Specification (Max mg/kg) Jetez un oeil à Technique
Acéphate < 0,01 GC-MS, LC-MS/MS
Aldrin + Dieldrin < 0,01 GC-MS
BHC (α, β, γ, δ isomers) < 0,01 GC-MS
Chlordane (Complete) < 0,01 GC-MS
DDT (Complete) < 0,01 GC-MS
Endrin < 0,01 GC-MS
Fenvalerate < 0,01 GC-MS
Heptachlor + Epoxide < 0,01 GC-MS
Hexachlorobenzène < 0,01 GC-MS
Malathion < 0,01 GC-MS
Methoxychlor < 0,01 GC-MS
Parathion < 0,01 GC-MS
Pyrethrins (Complete) < 0,01 GC-MS

Desk 2: Heavy Steel Limits

Heavy Steel Venture Specification (Max ppm) Jetez un oeil à Technique
Arsenic (As) ≤ 1,0 ICP-MS, USP <232>/EP 2.4.27
Cadmium (Cd) ≤ 1,0 ICP-MS, USP <232>/EP 2.4.27
Plomb (Pb) ≤ 1,0 ICP-MS, USP <232>/EP 2.4.27
Mercure (Hg) ≤ 0,1 ICP-MS, USP <232>/EP 2.4.27

Desk 3: Microbiological Requirements

Microbiological Venture Spécification Jetez un oeil à Technique
Complete Cardio Microbial Depend ≤ 1 000 UFC/g USP <61>, EP 2.6.12
Levures et moisissures mixtes complètes ≤ 100 UFC/g USP <61>, EP 2.6.12
Escherichia coli Absent dans 10 g USP <62>, EP 2.6.13
Salmonella espèces Absent dans 25g USP <62>, EP 2.6.13
Staphylococcus aureus Absent dans 1 g USP <62>, EP 2.6.13
Pseudomonas aeruginosa Absent dans 1 g USP <62>, EP 2.6.13

8. Cours de fabrication supérieure
Shaanxi Zhonghong employs a classy, multi-stage Conforme aux BPF course of to make sure the best purity Reb A:

  1. Sourcing & Pre-treatment: Choix de prime Stevia rebaudiana leaves; washing, drying, and milling.

  2. Extraction: Sizzling water or food-grade solvent extraction to solubilize steviol glycosides.

  3. Purification majeure : Filtration and centrifugation to take away insoluble plant materials.

  4. Décoloration et déionisation : Elimination of pigments, organic acids, and salts utilizing activated carbon and ion-exchange resins.

  5. Superior Chromatographic Separation: Macroporous adsorption resin chromatography and/or HPLC préparative are critically employed to isolate and extremely purify Rebaudioside A from different glycosides (e.g., Stevioside, Reb C, Reb D).

  6. Cristallisation: Managed crystallization to acquire high-purity Reb A crystals.

  7. Séchage: Séchage par atomisation ou vacuum drying to attain the ultimate powder type.

  8. Mélange et standardisation : Guaranteeing constant Reb A content material and efficiency.

  9. Rigorous High quality Management: Complete analytical testing at each important stage (HPLC, UHPLC, NMR, GC-MS, ICP-MS, microbiology).

  10. Conditionnement: Sealed in food-grade, multi-layer moisture-barrier packaging (e.g., aluminum foil luggage inside cartons).

9. Scénarios d'application clés

  • Repas et boissons : Smooth drinks, juices, flavored waters, yogurt, ice cream, confectionery (chocolate, candies), baked items, sauces, dressings.

  • Nutraceutiques et diététiques Compléments alimentaires : Tablets, capsules, powders, gummies for weight administration, blood sugar assist.

  • Médicaments sur ordonnance : Sweetening agent in syrups, chewable tablets, and liquid formulations.

  • Tabletop Sweeteners: Liquid drops, sachets, and granulated blends.

  • Oral Care Merchandise: Toothpaste, mouthwash (non-cariogenic profit).

  • Produits de beauté: Sometimes utilized in lip merchandise.

10. Stringent High quality Management (QC)
High quality is paramount at Shaanxi Zhonghong. Our multi-tiered QC protocol begins with incoming uncooked materials inspection of stevia leaves for authenticity, moisture, and preliminary contaminants. Contrôles en cours de fabrication (IPC) are rigorously utilized all through extraction, purification, chromatography, and crystallization, using real-time HPLC/UHPLC monitoring to trace glycoside profiles and guarantee goal purity ranges are met earlier than continuing. Ultimate product launch requires full conformance testing in opposition to all specs outlined in Part 7 (Purity by HPLC/UHPLC, Residues by GC-MS/LC-MS/MS, Heavy Metals by ICP-MS, Microbiology per USP/EP). Our cutting-edge analytical capabilities, avec quantitative NMR (qNMR) for absolute purity affirmation, Spectrométrie de masse (MS) for structural elucidation and hint contaminant identification, and recherche accélérée sur la stabilité, assure batch-to-batch consistency, security, and efficacy. We adhere strictly to ISO, HACCP, and cGMP ideas, sustaining complete documentation for full traceability.

11. Safe Packaging & International Logistics

  • Conditionnement: 1kg, 5kg, 10kg, 25kg food-grade aluminum foil luggage with HDPE inside lining, vacuum-sealed or flushed with nitrogen, positioned inside fiberboard drums ou corrugated cartons. Customized packaging accessible.

  • Stockage: Détaillant dans un cool, dry place (<25°C, <65% RH) in authentic, unopened packaging. Shelf life sometimes 24 months.

  • Logistique: Shipped by way of air freight or sea freight globally. Certificates of Evaluation (CoA), Certificates of Origin (CoO), and Materials Security Knowledge Sheet (MSDS) accompany all shipments. Compliant with worldwide customs and meals security laws.

12. Deep Dive: Well being Mechanisms, Innovation & Analysis

  • Mécanismes de bien-être : Reb A interacts with candy style receptors (T1R2/T1R3) on the tongue. In contrast to sugar, it’s not metabolized for vitality within the physique; it passes by way of unmetabolized or is metabolized by intestine micro organism into steviol, which is absorbed, glucuronidated within the liver, and excreted in urine. This pathway underpins its zero-calorie standing and lack of affect on blood glucose.

  • Business Purposes & Tech Innovation: Demand drives innovation in extraction effectivity (ultrasound, microwave-assisted), purification selectivity (novel adsorbents, simulated transferring mattress chromatography), style modulation (enzymatic glycosylation to create next-gen molecules like Reb D, M; mixing science), and fins (bettering solubility/stability in advanced matrices).

  • Frontières et défis de l'analyse : Ongoing analysis explores metabolic results past sweetness (intestine microbiome modulation, anti-inflammatory potential), refined sensory prediction fashionscost-effective large-scale manufacturing of minor, cleaner-tasting glycosides (Reb M, D), regulatory harmonization, and shopper schooling on style notion.

13. Rebaudioside A FAQs

  • Q: Is Rebaudioside A secure? UN: Sure, main world well being authorities (FDA, EFSA, JECFA, FSANZ) approve high-purity steviol glycosides, together with Reb A, as secure for consumption throughout the established ADI.

  • Q: Does Reb A have an effect on blood sugar? UN: No, Rebaudioside A has a zero glycemic index and doesn’t increase blood glucose or insulin ranges, making it appropriate for diabetics.

  • Q: Why select Reb A over Stevioside? UN: Reb A usually has a cleaner, sweeter style profile avec much less bitterness and licorice aftertaste in comparison with Stevioside.

  • Q: Can I bake with Reb A? UN: Sure, Reb A is warmth secure, making it appropriate for baking and cooking purposes.

  • Q: Are there any unintended effects? UN: Reb A is well-tolerated. Consuming quantities vastly exceeding the ADI may trigger gentle digestive upset in delicate people, however that is unusual at typical utilization ranges.

  • Q: Is Reb A pure? UN: Sure, it’s extracted and purified straight from the Stevia leaf, qualifying as a pure sweetener.

  • Q: How is it completely different from synthetic sweeteners? UN: In contrast to synthetic sweeteners (e.g., aspartame, sucralose), Reb A is derived from a plant supply and is mostly perceived extra favorably by customers searching for pure substances.

14. The place to Purchase Excessive-High quality Rebaudioside A?
Supply premium, high-purity Rebaudioside A straight from the producer, Shaanxi Zhonghong Investment Technology Co., Ltd.:

15. Conclusion
Rebaudioside A stands because the gold commonplace throughout the pure high-intensity sweetener market, pushed by its distinctive purity, superior style profile, zero-calorie nature, and confirmed security. As shopper demand for sugar discount and clear labels continues to surge, Reb A provides an indispensable resolution for revolutionary meals, beverage, and well being product formulators. Shaanxi Zhonghong Investment Technology Co., Ltd., with its 28-year legacy, cutting-edge purification expertise, unwavering dedication to high quality exceeding business benchmarks (20%+ purity benefit), and strong world provide chain, is your strategic companion for securing a dependable provide of premium-grade Rebaudioside A. Associate with us to raise your product formulations and meet the evolving calls for of the health-conscious world market.

16. Références

  1. European Meals Security Authority (EFSA). (2010). Scientific Opinion on the protection of steviol glycosides for the proposed makes use of as a meals additive. Journal de l'EFSA, 8(4), 1537.

  2. Meals and Agriculture Group / World Well being Group (FAO/WHO) Joint Skilled Committee on Meals Components (JECFA). (2016). Specs for Steviol Glycosides. Monograph 21.

  3. U.S. Meals and Drug Administration (FDA). GRAS Notices: GRN No. 252 (Steviol Glycosides), GRN No. 732 (Reb M). [Access via FDA website].

  4. Purkayastha, S., et al. (2016). Steviol Glycosides in Industrial Stevia Merchandise: Compositional Evaluation and Their Relationship to Sweetness. Journal de chimie agricole et alimentaire, 64(4), 678–686.

  5. Ashwell, M. (2015). Stevia, Nature’s Zero-Calorie Sustainable Sweetener: A New Participant within the Combat Towards Weight problems. Vitamin As we speak, 50(3), 129–134.

  6. Shankar, P., et al. (2013). Non-nutritive sweeteners: evaluation and replace. Vitamine, 29(11–12), 1293–1299. (PubMed ID: 23845273)

  7. Worldwide Stevia Council (ISC). [Industry resources & science summaries].

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