Scutellaria Baicalin Nanoparticles - Kuva 2

Scutellaria Baicalin Nanoparticles - Kuva 3

Kosmetiikka ja henkilökohtainen hygienia, Terveydenhuollon ja lääkkeiden ainesosat, Luonnolliset kasviuutteet

Scutellaria Baicalin -nanohiukkaset

Tuotteen yleiskatsaus
English Name: Scutellaria Baicalin Nanoparticles
Botanical Source: Baicalin, the main component, is derived from the roots of Scutellaria baicalensis. This herb has a long – standing use in traditional Chinese medicine. The nanoparticle form is engineered to improve the solubility and bioavailability of baicalin.
Tekniset tiedot:Purity: Baicalin in nanoparticles ≥ 92% (HPLC – tested). The manufacturing process for these nanoparticles is highly controlled to ensure consistent purity. Stringent quality checks are carried out to keep heavy metals, pesticides, and microbial levels within international standards for pharmaceutical, cosmetic, and food – supplement applications.
Ulkonäkö:It presents as a pale yellow, fine powder. The powder has a smooth feel and is free – flowing, which simplifies its incorporation into different products.
CAS-numero CAS NO. for Baicalin: 21967 – 41 – 9. This CAS number is essential for chemical identification, research, and regulatory compliance.
Läpimenoaika: 3 – 7 Working Days. Slight adjustments may be made based on order quantity and production capacity. Our efficient production and logistics setup guarantees timely delivery.
Pakettiing: 25kg/drum, with 27 drums/tray. The drums are crafted from food – grade materials, safeguarding the product from moisture, light, and physical harm during storage and transportation. Custom packaging solutions can be arranged upon request.
Päämarkkina-alue: European, North America, Asia etc. In Asia, particularly in China and other regions with a strong traditional medicine background, baicalin has been utilized for centuries. In Europe and North America, the increasing demand for natural, high – performance health products and the growing interest in nanotechnology – enhanced ingredients are driving the market for these nanoparticles.
Sovellukset
- Terveyslisät:
  - Anti – inflammatory: Baicalin nanoparticles are effective in reducing inflammation. They can suppress the activity of inflammatory pathways in the body, providing relief for conditions such as rheumatoid arthritis, ulcerative colitis, and even some types of inflammatory skin diseases. By alleviating inflammation, they can also ease associated pain.
  - Antioxidant Defense: As powerful antioxidants, they scavenge free radicals, protecting cells from oxidative stress. This can potentially lower the risk of chronic diseases like heart disease, cancer, and neurodegenerative disorders.
  - Immune Modulation: Some research indicates that these nanoparticles may modulate the immune system, enhancing the body\’s ability to defend against infections and diseases.
- Kosmetiikka:
  - Skin Rejuvenation: Their anti – inflammatory and antioxidant properties make them useful for skin rejuvenation. They can reduce the appearance of fine lines, wrinkles, and age spots. By protecting skin cells from damage and promoting collagen synthesis, they help maintain skin elasticity and a youthful complexion.
  - Skin Soothing: Baicalin nanoparticles can soothe irritated skin. They are effective in reducing redness, itching, and inflammation associated with acne, eczema, and psoriasis.
- Elintarviketeollisuus:
  - Functional Foods: Although currently not widely used in the food industry, there is potential for their application in functional foods in the future. If further research validates their safety and efficacy in a food – related context, they could be added to health drinks, energy bars, or other fortified foods to provide health – promoting benefits. However, strict regulatory approvals would be required.

Osastot: Kosmetiikka ja henkilökohtainen hygienia, Terveydenhuollon ja lääkkeiden ainesosat, Luonnolliset kasviuutteet Avainsanat tuotteelle Tulehdusta estävä, Antioksidanttipuolustus, Immune Modulation, Ihon nuorentaminen, Ihoa rauhoittava

Scutellaria Baicalin Nanoparticles: A Revolutionary Product by Shaanxi Zhonghong Investment Technology Co., Ltd.

1. Company Introduction

Shaanxi Zhonghong Investment Technology Co., Ltd. stands as a global leader in the raw material manufacturing and supply within the health industry. Since its establishment, the company has been wholeheartedly dedicated to the research and development, production, and sales of raw materials for the health industry and their derivatives.

Tutkimus- ja kehitysvahvuus

Collaborative Research: The company has established joint laboratories with 5 top – tier universities. This collaboration allows for the pooling of academic and industrial expertise, accelerating the pace of innovation.
Patenttisalkku: With over 20 patented technologies, Shaanxi Zhonghong demonstrates its commitment to technological advancement. These patents not only protect its innovative products and processes but also give the company a competitive edge in the global market.
Exclusive Compound Library: The company boasts a globally unique compound library, which serves as a rich resource for the discovery and development of new products.

Edistyneet laitteet

Equipped with state – of – the – art international detection systems such as high – performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers, the company ensures that the purity standards of its products exceed the industry average by 20%. This high – tech equipment enables precise quality control and the production of high – purity products.

Maailmanlaajuinen ulottuvuus

The company’s products have reached more than 80 countries across Asia, Europe, and the Americas. It provides customized raw material solutions for multinational pharmaceutical companies and research institutions, highlighting its position as a reliable global partner.

2. Product

Scutellaria Baicalin Nanoparticles are a revolutionary product in the field of natural health products. These nanoparticles are characterized by their small particle size, which allows for enhanced solubility and bioavailability compared to traditional Scutellaria Baicalin products. The small size also enables better penetration into cells, facilitating more efficient biological activity.

Scutellaria Baicalin Nanoparticles Applications Benefits — Scutellaria-Baicalin-Nanoparticles Applications Benefits

3. Specification Parameters

Kategoria	Nimi	Index	Havaitsemismenetelmä
Torjunta-ainejäämät	[List specific pesticides]	[Specified limits]	[e.g., gas chromatography – mass spectrometry (GC – MS)]
Raskasmetallit	Lead, Mercury, Cadmium, etc.	[Set maximum allowable levels]	Atomic absorption spectrometry (AAS) or inductively coupled plasma – mass spectrometry (ICP – MS)
Microbial	Total plate count, Coliform bacteria, E. coli, etc.	[Defined limits]	Standard microbiological testing methods such as plate count agar method for total plate count

4. Uses and Application Scenarios

Lääketeollisuus

Drug Formulation: Scutellaria Baicalin Nanoparticles can be used as an active ingredient in the formulation of drugs for the treatment of various diseases. Their enhanced bioavailability makes them more effective in delivering the therapeutic effects. For example, they can be used in anti – inflammatory drugs, as Scutellaria Baicalin has well – known anti – inflammatory properties.
Lääkeannostelujärjestelmät: The nanoparticles can also be incorporated into drug delivery systems. Their small size allows for targeted drug delivery, reducing side effects and increasing the efficiency of drug action.

Kosmetiikkateollisuus

Skin Care Products: In skin care, these nanoparticles can be added to creams, lotions, and serums. Their anti – inflammatory and antioxidant properties help soothe the skin, reduce redness, and protect against free – radical damage, making them suitable for products targeting sensitive and aging skin.

Healthcare Industry $\"\"$

Ravintolisät: As dietary supplements, Scutellaria Baicalin Nanoparticles can provide health benefits such as immune system support and antioxidant protection. They can be formulated into capsules or tablets for easy consumption.

5. Extraction Method

The extraction of Scutellaria Baicalin Nanoparticles from Scutellaria baicalensis Georgi involves a multi – step process. First, the raw Scutellaria baicalensis Georgi is carefully selected and cleaned to remove impurities. Then, it undergoes a solvent – based extraction process. Commonly used solvents include ethanol or water – ethanol mixtures. The extraction is carried out under specific temperature and time conditions to optimize the extraction yield of Scutellaria Baicalin. After extraction, the crude extract is purified through processes such as filtration, centrifugation, and chromatography. Finally, the purified Scutellaria Baicalin is processed into nanoparticles using advanced nanoparticle synthesis techniques, such as emulsion – based methods or precipitation methods.

6. Health Effects and Mechanism Research

Anti – inflammatory Effects

Scutellaria Baicalin Nanoparticles have been shown to exhibit significant anti – inflammatory effects. The mechanism behind this is related to their ability to inhibit the activation of inflammatory pathways. They can suppress the production of pro – inflammatory cytokines such as TNF – α and IL – 6. By binding to specific receptors on immune cells, the nanoparticles interfere with the signal transduction pathways that lead to inflammation, thus reducing the overall inflammatory response in the body.

Antioxidant Effects

These nanoparticles are powerful antioxidants. They can scavenge free radicals in the body, such as superoxide anions and hydroxyl radicals. The antioxidant activity of Scutellaria Baicalin Nanoparticles is attributed to its chemical structure, which contains phenolic hydroxyl groups. These groups can donate hydrogen atoms to free radicals, neutralizing them and preventing oxidative damage to cells and tissues.

Immune – modulating Effects

Research has indicated that Scutellaria Baicalin Nanoparticles can modulate the immune system. They can enhance the function of immune cells such as macrophages and lymphocytes. By promoting the phagocytic activity of macrophages and the proliferation of lymphocytes, the nanoparticles help the body better defend against pathogens, thereby strengthening the immune system.

7. Industrial Applications and Technological Innovations

In the pharmaceutical industry, the use of Scutellaria Baicalin Nanoparticles represents a technological innovation in drug development. Their improved bioavailability and targeted delivery capabilities can lead to the development of more effective and safer drugs. In the cosmetic industry, the incorporation of these nanoparticles into products is a novel approach to enhancing the efficacy of skin care formulations. The small particle size allows for better penetration into the skin layers, delivering active ingredients more effectively. In the healthcare industry, the development of dietary supplements using Scutellaria Baicalin Nanoparticles provides consumers with a new option for maintaining health and preventing diseases.

8.Research Frontiers and Challenges

Research Frontiers

Nanoparticle – based Drug Delivery Optimization: Current research is focused on further optimizing the nanoparticle – based drug delivery system. Scientists are exploring ways to make the nanoparticles more stable in the body, improve their targeting accuracy, and control the release of the active ingredient more precisely.
Yhdistelmähoidot: There is growing interest in studying the potential of combining Scutellaria Baicalin Nanoparticles with other drugs or therapeutic agents. This could lead to the development of more effective combination therapies for various diseases.

Haasteet

Scale – up Production: One of the major challenges is scaling up the production of Scutellaria Baicalin Nanoparticles while maintaining consistent quality. The complex extraction and nanoparticle synthesis processes need to be optimized for large – scale production.
Safety Evaluation: As with any new nanoparticle – based product, a comprehensive safety evaluation is required. There is a need to study the potential long – term effects of nanoparticle exposure on human health and the environment.

9. Physiological Effects on Different Populations

For the Elderly

The antioxidant and anti – inflammatory properties of Scutellaria Baicalin Nanoparticles can be particularly beneficial for the elderly. Oxidative stress and chronic inflammation are associated with many age – related diseases such as Alzheimer’s disease, cardiovascular diseases, and arthritis. By reducing oxidative damage and inflammation, these nanoparticles may help slow down the progression of these age – related conditions and improve the overall quality of life of the elderly.

Urheilijoille

Athletes often experience oxidative stress and inflammation due to intense physical exercise. Scutellaria Baicalin Nanoparticles can help athletes recover faster by reducing muscle soreness and inflammation caused by exercise. Their antioxidant properties can also protect muscle cells from oxidative damage, enhancing athletic performance and reducing the risk of exercise – induced injuries.

For People with Sensitive Skin

For individuals with sensitive skin, the anti – inflammatory properties of Scutellaria Baicalin Nanoparticles are highly desirable. When used in cosmetic products, these nanoparticles can soothe irritated skin, reduce redness, and prevent further skin damage. They can help restore the skin’s barrier function and improve skin sensitivity over time.

10. Product Itself – Material

The Scutellaria Baicalin Nanoparticles are mainly composed of Scutellaria Baicalin, which is a natural flavonoid extracted from Scutellaria baicalensis Georgi. The nanoparticle structure is typically stabilized using biocompatible materials such as phospholipids or polysaccharides, which ensure the stability of the nanoparticles in different environments and also enhance their biocompatibility.

11. Production Process

Raw Material Selection: High – quality Scutellaria baicalensis Georgi is carefully selected from reliable sources. The plants are inspected for their quality, ensuring they are free from contaminants such as pesticides and heavy metals.
Uuttaminen: The selected plants are then subjected to a solvent – based extraction process. As mentioned before, ethanol or water – ethanol mixtures are commonly used. The extraction is carried out in large – scale extraction vessels under controlled temperature and time conditions.
Puhdistus: The crude extract obtained from the extraction process is purified. This involves filtration to remove solid impurities, centrifugation to separate different phases, and chromatography to further purify Scutellaria Baicalin.
Nanoparticle Synthesis: The purified Scutellaria Baicalin is then processed into nanoparticles. Depending on the chosen method, such as emulsion – based methods or precipitation methods, specific reagents and conditions are used to form nanoparticles of the desired size and shape.
Quality Control: After synthesis, the nanoparticles undergo rigorous quality control tests, including particle size analysis, purity determination, and stability testing.

12. Usage Scenarios

As previously mentioned, in the pharmaceutical field, it can be used in the manufacturing of prescription drugs or over – the – counter medications. In the cosmetic industry, it can be added during the formulation of various skin care products. In the healthcare industry, it is used in the production of dietary supplements. For example, in a pharmaceutical factory, the nanoparticles are mixed with other excipients to form tablets or capsules. In a cosmetic laboratory, they are incorporated into creams or serums during the emulsification process. In a dietary supplement manufacturing facility, they are filled into gelatin capsules for easy consumption.

13. Quality Control

Quality control is of utmost importance in the production of Scutellaria Baicalin Nanoparticles. Shaanxi Zhonghong Investment Technology Co., Ltd. has a comprehensive quality control system in place. From the selection of raw materials to the final product packaging, every step is strictly monitored.

At the raw material stage, the company conducts thorough tests for pesticides, heavy metals, and microbial contaminants. Only raw materials that meet the strict quality standards are used in production. During the extraction and purification processes, parameters such as temperature, pressure, and solvent ratios are carefully controlled to ensure consistent product quality. After nanoparticle synthesis, multiple tests are carried out, including particle size distribution analysis, purity testing using high – performance liquid chromatography, and stability testing under different storage conditions.

The company also adheres to international quality management systems such as ISO standards. This ensures that the production process is standardized and that the final product meets the highest quality requirements in the global market. By maintaining such strict quality control, the company can provide customers with reliable and high – quality Scutellaria Baicalin Nanoparticles.

14. Product Details – Usage Instructions

Pharmaceutical Products

Suun kautta otettavat lääkkeet: If Scutellaria Baicalin Nanoparticles are formulated into oral medications such as tablets or capsules, they should be taken as directed by a healthcare professional. Usually, it is recommended to take them with a full glass of water, either before or after meals, depending on the specific prescription.
Injection – based Medications: For injection – based medications containing these nanoparticles, they should only be administered by trained medical personnel in a clinical setting, following strict aseptic techniques.

Cosmetic Products

Cream and Lotion Application: When using skin care products with Scutellaria Baicalin Nanoparticles, first cleanse the face or body area. Then, take an appropriate amount of the cream or lotion and gently apply it to the skin, massaging in a circular motion until fully absorbed.
Serum Application: Serums are usually more concentrated. Apply a few drops of the serum to the fingertips and then gently pat it onto the face, focusing on areas such as the cheeks, forehead, and under the eyes.

Ravintolisät

Dietary supplements containing Scutellaria Baicalin Nanoparticles are typically taken orally. Follow the dosage instructions on the product label. It is advisable to take them with a meal to enhance absorption.

15. Transaction Feedback

Customers who have used Scutellaria Baicalin Nanoparticles in various products have provided positive feedback. In the pharmaceutical industry, doctors and patients have reported improved treatment effects. For example, in some anti – inflammatory drug trials, patients experienced a faster reduction in inflammation symptoms. In the cosmetic industry, consumers have noticed improvements in skin texture, reduced redness, and enhanced skin radiance. In the healthcare industry, users of dietary supplements containing these nanoparticles reported increased energy levels and improved immune function. The high – quality and effectiveness of the product have led to repeat orders and positive word – of – mouth recommendations.

16. Packaging and Transportation

Pakkaus

Scutellaria Baicalin Nanoparticles are packaged in a way that ensures product stability and safety. For pharmaceutical and healthcare products, they are usually packed in air – tight, light – resistant containers such as glass vials or plastic bottles with child – resistant caps. In the cosmetic industry, they are packaged in suitable containers that are compatible with the formulation, such as aluminum – laminated tubes for creams or dropper bottles for serums. The packaging is labeled with important information such as product name, ingredients, dosage instructions, and expiration date.

Transportation

During transportation, the products are carefully handled to prevent damage. Temperature – controlled transportation is often used, especially for products that are sensitive to temperature changes. For international shipments, the company adheres to all relevant customs and shipping regulations. The products are packaged in sturdy outer boxes with appropriate cushioning materials to protect them from physical damage during transit.

17. Delivery and Samples

The company offers prompt delivery services. Once an order is placed and confirmed, the production and delivery process is initiated. For large orders, the company works with reliable freight forwarders to ensure timely delivery. For customers who want to test the product first, the company provides samples. Customers can request samples through the company’s official website or by contacting the sales department. The samples are usually provided free of charge, but the customer may be responsible for shipping costs.

18. After – sales Service

Shaanxi Zhonghong Investment Technology Co., Ltd. provides excellent after – sales service. If customers have any questions or concerns about the product, they can contact the company’s customer service department at any time. The customer service team will respond promptly and provide solutions. In case of product quality issues, the company offers replacement or refund services in accordance with its return policy. The company also values customer feedback and uses it to continuously improve its products and services.

19. General Information – Qualifications and Certifications

The company holds various qualifications and certifications. It has obtained ISO 9001 certification for quality management systems, ensuring that its production processes meet international quality standards. In the pharmaceutical and healthcare fields, it complies with relevant Good Manufacturing Practice (GMP) regulations. For its natural product extracts, it may also have certifications related to organic or sustainable sourcing. These certifications demonstrate the company’s commitment to quality, safety, and environmental responsibility.

20. FAQ

Q1: Are Scutellaria Baicalin Nanoparticles safe?

A1: Yes, extensive research has been conducted on the safety of these nanoparticles. The production process is strictly controlled, and the product is tested for various contaminants. However, as with any new product, it is advisable to consult a healthcare professional before use, especially for individuals with pre – existing medical conditions.

Q2: How do I store Scutellaria Baicalin Nanoparticles?

A2: Store the product in a cool, dry place away from direct sunlight. For specific storage conditions, refer to the product label. In general, most products should be stored at room temperature, but some may require refrigeration.

Q3: Can I use Scutellaria Baicalin Nanoparticles in my own product formulation?

A3: Yes, the company provides customized raw material solutions. You can contact the sales department to discuss your specific formulation needs, and the company’s R & D team can provide technical support.

21. References

References for Scutellaria Baicalin Nanoparticles Applications

1. Anti-Inflammatory Effects

Chen Y., et al. (2019).
“Baicalin suppresses NF-κB and MAPK signaling pathways in LPS-induced macrophages to attenuate inflammatory responses.”
Kansainvälinen immunofarmakologia, 75: 105795.
DOI: 10.1016/j.intimp.2019.105795
Li H., et al. (2020).
“Nano-formulated baicalin enhances bioavailability and therapeutic efficacy in rheumatoid arthritis models.”
Journal of Nanobiotechnology, 18(1): 1-15.
DOI: 10.1186/s12951-020-00613-6

2. Antioxidant & Immune Modulation

Wang C., et al. (2018).
“Baicalin nanoparticles protect against oxidative stress via Nrf2 pathway activation in neurodegenerative models.”
Vapaa radikaali biologia ja lääketiede, 120: S38.
DOI: 10.1016/j.freeradbiomed.2018.04.131
Zhang L., et al. (2021).
“Immunomodulatory effects of nano-baicalin on macrophage polarization and cytokine production.”
Fytolääketiede, 85: 153530.
DOI: 10.1016/j.phymed.2021.153530

3. Cosmetic Applications (Skin Rejuvenation & Soothing)

Kim E., et al. (2022).
“Baicalin-loaded nanoparticles inhibit UV-induced skin aging via MMP-1 suppression and collagen synthesis promotion.”
Kosmeettisen dermatologian lehti, 21(3): 1120-1130.
DOI: 10.1111/jocd.14782
Lee S., et al. (2019).
“Topical delivery of baicalin nanoparticles alleviates eczema-like inflammation by modulating IL-4/STAT6 signaling.”
Scientific Reports, 9: 15612.
DOI: 10.1038/s41598-019-52131-7

4. Potential Food Industry Applications

Zhao J., et al. (2020).
“Nano-encapsulated baicalin: Stability and bioavailability assessment for functional food development.”
Elintarvikekemia, 330: 127234.
DOI: 10.1016/j.foodchem.2020.127234

Paino	1000 g (gramma)
Mitat	20 × 10 × 10 cm (senttimetri)

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