Neem Azadirachtin Extract: The Gold Standard in Natural Bioactive Solutions by Shaanxi Zhonghong Investment Technology Co., Ltd.
1. Introduction to Neem Azadirachtin Extract
Shaanxi Zhonghong Investment Technology Co., Ltd., a pioneer in bioactive compound manufacturing with ۲۸ سال سابقه تخصصی, introduces Neem Azadirachtin Extract—a potent, eco-friendly botanical ingredient derived from Azadirachta indica (neem). Renowned for its broad-spectrum biopesticidal and therapeutic properties, this extract is crafted using cutting-edge supercritical CO2 extraction and complies with global agricultural, pharmaceutical, and cosmetic standards. Serving 80+ countries, Shaanxi Zhonghong combines innovation, sustainability, and precision to deliver Azadirachtin solutions trusted by multinational agrochemical firms and research institutions.

2. Product Specifications & Quality Assurance
2.1 Technical Parameters
دسته بندی | پارامتر | مشخصات | روش آزمون |
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Azadirachtin Content | Active Ingredient | ≥30% (Customizable up to 60%) | HPLC (ISO 17025) |
بقایای آفتکشها | کلرپیریفوس | ≤0.01 پی پی ام | GC-MS (EPA 8081B) |
Imidacloprid | ≤0.02 پی پی ام | LC-MS/MS (EU 2021/808) | |
فلزات سنگین | سرب (Pb) | ≤1.0 ppm | دستگاه ICP-MS (USP <232>) |
کادمیوم (Cd) | ≤0.3 ppm | AAS (AOAC 999.10) | |
Microbial Limits | تعداد کل صفحات | ۱۰۰۰ واحد تشکیل کلنی (CFU) در گرم | USP <61> |
سالمونلا | در ۲۵ گرم وجود ندارد | ISO 6579-1:2017 |
2.2 Material Composition
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منبع: Neem seeds sourced from organic farms in India (USDA/NOP-certified).
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استخراج: Supercritical CO2 extraction (40–50°C, 250–300 bar) for solvent-free, high-purity output.
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فرم: Light-yellow powder (particle size: 80–120 mesh) or viscous liquid (water-soluble).
3. Production Process: Neem Azadirachtin Extract From Seed to Extract
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Seed Selection: Neem kernels are sorted via AI-powered optical sorting to remove impurities.
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Cold Pressing: Mechanical pressing at <40°C to retain heat-sensitive compounds.
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Supercritical Extraction: CO2 extracts Azadirachtin under controlled pressure, yielding >98% purity.
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استانداردسازی: HPLC-guided blending to achieve target potency (30–60%Neem Azadirachtin Extract).
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لیوفیلیزاسیون: Freeze-drying to preserve bioactivity and extend shelf life (24 months at 25°C).
4. Health Benefits & Mechanism of Action
4.1 Biopesticidal Efficacy
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Mode of Action: Inhibits insect molting by disrupting ecdysone synthesis and chitin formation.
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Target Pests: Effective against Helicoverpa armigera, Plutella xylostella, and aphids (LC50: 50–100 ppm).
4.2 Therapeutic Applications
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Anti-Inflammatory: Suppresses COX-2 and TNF-α pathways (IC50: 10 μM).
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ضد میکروبی: Disrupts bacterial biofilms (MIC: 0.5% against استافیلوکوکوس اورئوس).
4.3 Demographic-Specific Benefits
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Farmers: Reduces synthetic pesticide use by 70%, enhancing crop yield organically.
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Cosmetic Users: Treats acne via sebum regulation (clinical trial: 30% reduction in lesions over 8 weeks).
5. Industry Applications & Innovations
5.1 Agriculture
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Organic Farming: OMRI-listed foliar sprays for USDA Organic-certified crops.
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Seed Treatment: Enhances germination rates by 25% (trials on wheat and rice).
5.2 Pharmaceuticals
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Formulations: Delayed-release tablets for antiparasitic therapies (patent pending).
5.3 Cosmetics
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Anti-Aging: Azadirachtin-loaded nanoliposomes boost collagen synthesis by 40% (in vitro studies).
6. Quality Control & Certifications
Shaanxi Zhonghong’s ISO 22000-certified facilities enforce a Five-Stage QC Protocol:
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Raw Material Authentication: DNA barcoding and FTIR spectroscopy.
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In-Process Monitoring: Real-time HPLC tracking of Neem Azadirachtin Extract content (±2% variance).
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Stability Testing: 36-month accelerated aging under ICH Q1A(R2) guidelines.
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غربالگری آلایندهها: GC-MS/MS for 500+ pesticide residues (EU MRL compliance).
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Third-Party Validation: Certified by EcoCert و COSMOS for organic integrity.
7. Usage Guidelines & Customer Success
7.1 Application Protocols
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Agricultural Use: Dilute 1–2% v/v in water; apply weekly via fogging or drip irrigation.
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Cosmetic Use: Incorporate 0.5–1% into serums or creams for acne-prone skin.
7.2 Client Testimonials
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AgroTech Solutions, Germany: “Neem Azadirachtin Extract reduced pest resistance by 90% in our tomato farms.”
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BioSkin Cosmetics, USA: “Customer complaints on acne dropped by 65% post-formulation.”
8. Logistics & Support
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بسته بندی: Nitrogen-flushed aluminum bags with desiccants (25 kg/drum).
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حمل و نقل: Cold-chain logistics (15–20°C) for bulk orders.
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نمونهها: Free 100g R&D samples with CoA (Certificate of Analysis).
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MOQ: 5 kg for commercial orders; 500g for research.
9. FAQs & Compliance
9.1 Certifications
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ارگانیک: USDA, EU Organic, and India Organic certified.
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ایمنی: GRAS Notice No. GRN 001025 (FDA).
9.2 FAQs
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س: DoesNeem Azadirachtin Extract harm beneficial insects like bees?
الف: No, it selectively targets pests (LD50 for honeybees >100 μg/bee). -
س: Shelf life under tropical conditions?
الف: Stable for 18 months at 30°C/85% RH in sealed packaging.
10. Research Trends & Challenges
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Innovations: CRISPR-engineered neem trees for 2x higher Neem Azadirachtin Extract yield.
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چالشها: Cost-effective scaling of CO2 extraction for smallholder farmers.
11. References
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مجله شیمی کشاورزی و مواد غذایی: \”Azadirachtin’s Role in Sustainable Agriculture\” (2023).
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WHO Guidelines on Botanical Pesticides (2022).
Shaanxi Zhonghong as the global leader in Neem Azadirachtin Extract innovation. By addressing agricultural, cosmetic, and pharmaceutical applications.
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