بیوپرین

Bioperine®: The Gold Standard in Bioavailability Enhancement – A Manufacturer’s Guide

1. What is Bioperine®?

Let’s cut through the noise. Bioperine® is not just black pepper extract. It’s a patented, clinically-studied ingredient derived from the fruits of فلفل سیاه L. (black pepper) and standardized to contain ≥95% piperine. Think of it as the key that unlocks the full potential of your supplements. Its primary, and most valuable, function is to significantly enhance the bioavailability of other active compounds, making your formulations more effective and efficient.

۲. منبع، شیمی و مشخصات

• منبع: Sourced from the dried fruits of فلفل سیاه L.

• زیست‌فعال کلیدی: Piperine (Standardized to ≥95%).

• مشخصات شیمیایی:

  • شماره CAS: 94-62-2

  • م.ف: C₁₇H₁₉NO₃

  • مگاوات: 285.34 g/mol

  • آینک‌ها: 202-348-0

• ظاهر: Off-white to pale yellow crystalline powder.

• حلالیت: Soluble in ethanol and chloroform; sparingly soluble in water.

3. The Zhonghong Standard: Why Our Bioperine® is Best for B2B
برای nutraceutical ingredients suppliers و private label supplement manufacturers, consistency and proof are everything. Here’s what defines a premium-grade Bioperine®:

• Key Ingredient & Potency: ≥95% Piperine. This high level of purity is non-negotiable for reliable and potent bioavailability enhancement.

• Proven Efficacy (Compliant Claims):

  • Bioavailability Enhancer: Clinically shown to increase the absorption of various nutrients (e.g., Curcumin, CoQ10, Vitamins, Selenium).

  • Thermogenic Activity: Supports metabolic rate and nutrient utilization.

  • (Note: This product is not intended to diagnose, treat, cure, or prevent any disease. Structure/function claims must be compliant with local regulations).

• Optimal Use Level: Typically used at a 1-5% ratio relative to the active compound it is enhancing (e.g., 5-10mg of Bioperine® per 500mg of Curcumin). Dosage should be finalized based on the specific formulation.

• مبدا و کیفیت: Sourced from premium فلفل سیاه and processed to meet stringent international standards.

• کاربرد: Ideal for incorporation into tablets, capsules, and powder formulations for dietary supplements.

• Target Formulations: Essential for private label supplement manufacturers creating products with high-value actives like turmeric/curcumin, resveratrol, multivitamins, and cognitive health blends.

• Safety & Considerations:

  • Generally Recognized as Safe (GRAS): At recommended levels.

  • تداخلات دارویی: May affect the metabolism of certain pharmaceutical drugs by inhibiting cytochrome P450 enzymes and UDP-glucuronylation. Consult a medical expert if formulating for populations on medication.

  • بارداری/شیردهی: Recommended to avoid high doses.

4. Zhonghong Biotech: Your Strategic Ingredient Partner
When you need a reliable bulk botanical extracts partner, you need more than a vendor. You need a technical expert. شرکت فناوری سرمایه‌گذاری شانشی ژونگ‌هونگ دارای گواهینامه است تامین کننده مواد مغذی with 28 years of experience in bioactive compound manufacturing.

• تخصص‌های محوری: We are specialists in the precision extraction and purification of plant-derived actives. Our portfolio is built for B2B:

  • Standardized Botanical Extracts (like Bioperine®)

  • Cosmetic Raw Material Supplier offerings

  • مواد تشکیل دهنده مواد مغذی for supplements and functional foods

  • API Intermediates

• Our B2B Value Proposition:

  • Innovation-Driven: 20+ patents and university collaborations ensure we are at the forefront of extraction technology.

  • تضمین کیفیت: سرمایه‌گذاری ما در طیف‌سنجی HPLC و NMR guarantees a purity standard that is consistently 20% above common industry specs, providing you with a uncontested competitive edge.

  • Global B2B Network: We supply wholesale botanical extracts و راهکارهای سفارشی به عصاره‌های گیاهی OEM partners and major brands in over 80 countries.

5. Technical Insight: Mechanism of Action
Piperine’s primary mechanism is two-fold:

1. Inhibition of Metabolism: It inhibits the enzymes in the liver and intestine (e.g., CYP3A4, UGT) that would normally break down and eliminate other compounds before they enter the bloodstream.

2. Enhancing Absorption: It stimulates amino acid transporters in the intestinal lining and increases blood supply to the GI tract, facilitating greater uptake of co-administered supplements.

6. Uncompromising Quality Control: The COA
Our Quality Control is your formulation’s insurance policy. Every batch is rigorously tested.

Certificate of Analysis (COA) Summary – Bioperine® (≥95% Piperine)

۷. فرآیند تولید پیشرفته
Our GMP-compliant process ensures unmatched purity:

1. تامین و آماده سازی: Selection and cleaning of premium فلفل سیاه میوه‌ها

2. استخراج: Solvent extraction optimized for maximum piperine yield.

3. Filtration & Concentration: Removal of impurities and concentration of the extract.

4. تبلور و خالص‌سازی: Further refinement to achieve the ≥95% purity benchmark.

5. استانداردسازی: Precise adjustment to meet the exact specification.

6. خشک کردن و آسیاب کردن: Conversion into a fine, free-flowing powder.

7. انتشار کنترل کیفیت: The batch is only released after passing all critical quality parameters.

8. Application in Nutraceutical Formulations
This ingredient is a cornerstone for effective supplement design. Its primary application is in:

• Enhanced Absorption Formulas: Curcumin supplements, multivitamins, coenzyme Q10, resveratrol, and antioxidant blends.

• Weight Management Products: Leveraging its mild thermogenic properties.

• تغذیه ورزشی: To improve the uptake of amino acids and other performance nutrients.

9. B2B Packaging & Logistics

• بسته بندی: Standard 25kg/fiber drum with double polyethylene liners. Customized packaging available for عمده فروشی و فله سفارشات.

• ذخیره سازی: Store in a cool, dry place away from strong light.

• عمر مفید: 24 months when stored correctly.

• لجستیک: We handle global shipping and all export documentation (COA, MSDS, Certificate of Origin) for seamless delivery to نصب شده partners worldwide.

۱۰. برای نیازهای عمده خود به مواد اولیه با ما همکاری کنید
Zhonghong isn’t just a تامین کننده; we’re your innovation partner. We provide:

• قیمت گذاری رقابتی عمده فروشی: مستقیم دریافت کنید قیمت کارخانه برای سفارش‌های با حجم بالا

• سفارشی سازی و نصب شده: ما ارائه می‌دهیم عصاره‌های گیاهی OEM و راهکارهای سفارشی tailored to your specific formulation requirements.

• Technical Support: Leverage our 28 years of expertise for your product development.

برای دریافت قیمت یا درخواست نمونه با ما تماس بگیرید!

• وب: www.aiherba.com

• ایمیل: sales@aiherba.com; liaodaohai@gmail.com

• کلمات کلیدی: Bioperine supplier, bulk piperine, nutraceutical ingredients supplier, cosmetic raw material supplier, wholesale botanical extracts, private label supplement manufacturer, OEM herbal extracts, bulk organic ingredients.

۱۱. سوالات متداول برای مشتریان B2B

• Q: What is your Minimum Order Quantity (MOQ) for bulk orders?
  الف) برای جزئیات دقیق MOQ با ما تماس بگیرید. ما شرایط انعطاف‌پذیری را ارائه می‌دهیم. عمده فروشی و فله شرکا.

• Q: Can you provide custom standardization for private label?
  A: Absolutely. As an عصاره‌های گیاهی OEM partner, we specialize in راهکارهای سفارشی to meet your specific product specs.

• Q: Do you offer technical documentation and regulatory support?
  A: Yes. We provide full documentation (COA, MSDS) and can support with regulatory data for your market.

• س: زمان تحویل سفارشات بزرگ چقدر است؟
  A: Lead times vary based on order size. We maintain strategic stock for popular items and provide clear timelines for custom productions.

• Q: How do I start the qualification process?
  الف: به ما ایمیل بزنید به آدرس sales@aiherba.com برای درخواست یک نمونه رایگان and discuss your specific needs. Our technical team will guide you through the process.

۱۲. نتیجه‌گیری
In the competitive world of supplement manufacturing, ingredient efficacy is paramount. Bioperine® is a proven, powerful tool to differentiate your products and guarantee customer results. Sourcing from a technically advanced, reliable تولیدکننده is critical. Zhonghong Biotech, with its scientific rigor, proven quality, and global B2B supply capability, is the optimal partner for nutraceutical ingredients suppliers و برچسب خصوصی brands. Contact us today to discuss your project and request a sample.

مراجع:

• Majeed, M., et al. (1999). Piperine, a bioavailability enhancer. US Patent 5,972,382.

• Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. پلانتا مدیکا, 64(4), 353-356.

• Badmaev, V., et al. (2000). Piperine, an alkaloid derived from black pepper, increases serum response of beta-carotene during 14-days of oral supplementation. Nutrition Research, 20(3), 381-388.

• Johnson, J. J., et al. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. تحقیقات تغذیه و مواد غذایی مولکولی, 55(8), 1169-1176.