Icariin
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Icariin

Icariin factory supplier bulk Wholesale Extract factory

  1. Nombre en inglés: Icariin (pronounced “ick-uh-REEN”—it’s the main active compound in Epimedium plants, also called “Horny Goat Weed” (yes, that’s the real common name!); used in TCM for centuries)
  1. Especificación
    • Purity: 10%–98% (HPLC tested—most common for supplements is 20%–40%; higher purity (98%) is for research)
    • Solubility: Slightly soluble in water; dissolves well in ethanol and DMSO (works in capsules, tinctures, or topical gels—no clumps)
    • Moisture: ≤ 8% (keeps it dry, so it doesn’t lose its herbal potency)
    • Heavy Metals: ≤ 10 ppm (safe for oral use—meets TCM and global supplement standards)
    • Form: Fine powder (easy to mix into supplements or herbal blends)
  1. Apariencia: Light yellow to pale yellow powder with a mild, earthy, slightly bitter herbal aroma—no a yellowish-white solid with chocolate scent! It smells like dried Epimedium leaves—subtle, classic herbal smell.
  1. N.º CAS.: 489-32-7
  1. Plazo de entrega: 3–7 Working Days (we stock common purities (20%–40%) and high-purity (98%)—fast for supplement brands and TCM suppliers)
  1. Paquete:
    • Small sizes: 10g/100g amber glass jars (light-proof to protect potency) or 1kg resealable foil bags (great for small-batch products)
    • Bulk: 25kg food-grade drums (lined with plastic—27 drums per tray; includes desiccants to keep moisture out)
  1. Mercado principal: Global—Asia (TCM markets in China, Japan), Europe (herbal supplements), North America (men’s wellness and sports nutrition). Popular with people into traditional herbs or natural performance support.
  1. Applications & Main Benefits
    • Suplementos dietéticos
      • Men’s Wellness Capsules: 500–1000mg per serving (paired with tribulus or maca—traditional use for vitality support)
      • Joint Health Blends: Mixed with glucosamine or chondroitin (eases joint discomfort—thanks to anti-inflammatory effects)
      • Sports Performance Powders: Small doses (250–500mg) in pre-workout mixes (supports energy and endurance—popular with gym-goers)
    • Productos tradicionales de bienestar
      • TCM Decoctions: Added to herbal soups or teas (simmered with ginseng or goji berries—customized for vitality)
      • Herbal Tinctures: Diluted in ethanol (fast-acting—drops under the tongue for quick support)
    • Cosméticos (Marcas Naturales)
      • Anti-Aging Serums: 0.1%–0.5% concentration (boosts collagen production—fades fine lines; great for mature skin)
      • Hair Growth Oils: Mixed into scalp oils (nourishes follicles—reduces mild hair thinning; safe for daily use)
    • Research Uses
      • Bone Health Studies: Tested for supporting bone density (may help with osteoporosis—still in lab stages)
      • Cognitive Research: Explored for memory support (crosses the blood-brain barrier—early results look promising)

Key Benefits (Why It’s a TCM Staple!)

  • Vitality Support: Traditional use for men’s wellness—helps maintain healthy energy levels and performance (no harsh stimulants)
  • Joint Comfort: Reduces inflammation in joints—great for people with mild stiffness from exercise or aging
  • Antienvejecimiento: Fights free radicals and boosts collagen—keeps skin firm and reduces signs of aging (natural alternative to harsh chemicals)
  • Salud ósea: May support bone strength—helps with calcium absorption (useful for older adults or those at risk of bone loss)
  • Cognitive Boost: Early research shows it may support memory and focus—crosses the blood-brain barrier to target brain cells

Quick Tip

For supplements: Take icariin with a small amount of fat (like avocado or nuts)—it’s fat-soluble, so this helps your body absorb more of its benefits. If you’re new to it, start with a lower dose (500mg) to see how your body reacts—most people tolerate it well!
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Icariin: Premium Natural Compound for Nutraceutical & Pharmaceutical Applications – Manufacturer & Exporter Guide

1. What is Icariin?
For manufacturers seeking advanced natural compounds with proven biological activity, Icariin represents a premium flavonoid glycoside derived from Epimedium species (Horny Goat Weed). As the primary active compound responsible for Epimedium’s traditional uses, this sophisticated molecule offers significant potential in various health applications. Our high-purity Icariin provides consistent quality and reliable efficacy for nutraceutical, pharmaceutical, and cosmetic formulations where evidence-based natural ingredients are essential.

2. Fuente, química y especificaciones

  • Fuente: Extracted from leaves of Epimedium brevicornum and related species

  • Identidad química: 3,5,7-Trihydroxy-4′-methoxy-8-(3-hydroxy-3-methylbutyl)flavone-3-β-D-rhamnoside

  • Perfil químico:

    • N.º CAS: 489-32-7

    • MF: C₃₃H₄₀O₁₅

    • MW: 676.67 g/mol

    • EINECS: 610-101-1

  • Apariencia: Light yellow to white crystalline powder

  • Solubilidad: Soluble in methanol, ethanol; slightly soluble in water

  • Grados de pureza: 10%-98% HPLC purity available

3. The Premium Standard: Why Our Icariin Excels
Para clientes B2B requiring scientifically-backed natural compounds, our Icariin offers exceptional quality:

  • Ventajas clave:

    • Standardized Potency: Consistent biological activity batch-to-batch

    • Multiple Purity Options: Various concentrations for different applications

    • Respaldado por la investigación: Substantial scientific literature supporting mechanisms

  • Documented Benefits:

    • Apoyo para la salud ósea: Promotes osteoblast activity and bone formation

    • Physical Performance: Supports endurance and energy metabolism

    • Neuroprotective Effects: Demonstrates protective effects on neural cells

    • Apoyo cardiovascular: Exhibits vasodilatory and protective properties

  • Uso recomendado: 50-200 mg daily in supplements; 0.1-1% in cosmetic formulations

  • Certificaciones disponibles: cGMP, ISO 9001, Kosher, Halal

  • Aplicaciones objetivo: Bone health supplements, sports nutrition, cognitive support, cardiovascular health

  • Perfil de seguridad: Generally well-tolerated at recommended dosages

4. Zhonghong Biotech: Your Natural Compounds Specialist
Sourcing high-purity Icariin requires specialized botanical expertise.Tecnología de inversión Shaanxi Zhonghong Co., Ltd. combines 28 years of botanical extraction experience with advanced purification technology to deliver premium ingredients to global markets.

  • Capacidades técnicas:

    • Extracción avanzada: Optimized extraction protocols for maximum yield

    • Experiencia en purificación: Chromatographic separation for high purity grades

    • Seguro de calidad: Comprehensive analytical testing and validation

  • Cumplimiento global: Documentación completa que cumple con los estándares internacionales

5. Excelencia científica: mecanismo de acción
Icariin’s biological activity stems from multiple mechanisms:

  • Modulates BMP-2 and Wnt/β-catenin signaling pathways for bone formation

  • Inhibits PDE5 activity similar to conventional approaches

  • Exhibits antioxidant and anti-inflammatory properties

  • Shows neuroprotective effects through multiple pathways

6. Garantía de calidad de grado farmacéutico
Nuestro riguroso control de calidad garantiza que cada lote cumpla con los más altos estándares:

Certificate of Analysis (COA) Summary – Icariin (98%)

Categoría Parámetro Especificación Método de prueba
Identidad Huella dactilar de HPLC Referencia de cerillas HPLC-UV
Ensayo Icariin Content ≥ 98,0% HPLC-UV
Pureza Impurezas totales ≤ 2.0% HPLC-UV
Seguridad Metales pesados ≤ 10 ppm ICP-MS
Residuos de pesticidas Cumplir con los estándares de la EPA GC-MS/MS
Microbiología Recuento total de placa ≤ 1000 UFC/g USP <61>
Levadura/moho ≤ 100 UFC/g USP <61>

7. Proceso de fabricación avanzado
Our optimized production ensures maximum quality:

  1. Selección de materia prima: Premium Epimedium leaves from certified sources

  2. Extracción: Extracción de solventes optimizada para un rendimiento máximo

  3. Concentración: Concentración al vacío a baja temperatura

  4. Purificación: Purificación cromatográfica multietapa

  5. Cristalización: Precision crystallization for purity enhancement

  6. Control de calidad: Pruebas analíticas integrales

8. Aplicaciones y usos profesionales

  • Nutracéuticos: Bone health supplements, sports nutrition, vitality formulas

  • Productos farmacéuticos: Osteoporosis prevention, cardiovascular health

  • Productos cosméticos: Anti-aging skincare, hair growth formulations

  • Investigación: Biochemical studies, pharmacological research

Instrucciones de uso:

  • Suplementos dietéticos: 5-15% of formulation weight

  • Productos cosméticos: 0.5-2% in final formulations

  • Aplicaciones de investigación: Study-specific concentrations

  • Alimentos funcionales: As per regulatory allowances

9. Excelencia en la cadena de suministro global

  • Embalaje: 1kg double-bagged with oxygen scavengers, 25kg fiber drums

  • Almacenamiento: Cool, dry conditions away from light

  • Duración: 24 meses si se almacena correctamente

  • Logística: Envíos globales con soporte completo de documentación

10. Oportunidades de asociación
Ofrecemos:

  • Custom purity grades (10%, 50%, 98%)

  • Etiquetado privado y embalaje personalizado

  • Apoyo técnico para el desarrollo de formulaciones

  • Documentación reglamentaria para los mercados globales

Contacte con nuestro equipo técnico:

11. Preguntas frecuentes técnicas

  • Q: What’s the difference between Icariin and Epimedium extract?
    A: Icariin is the single active compound, while Epimedium extract contains multiple compounds

  • Q: Can you provide different purity levels?
    A: Yes, we offer from 10% to 98% purity for different applications

  • Q: Is your production GMP certified?
    A: Yes, we are a GMP certified plant extract fabricante

  • Q: Do you offer OEM services?
    A: Absolutely, we are an experienced OEM API supplier China

  • P: ¿Cuál es la cantidad mínima de pedido?
    A: El MOQ es de 1 kg para muestras y 25 kg para cantidades de producción.

12. Llamada final a la acción
Experience the superior quality of our Icariin for your formulations. As a leading dietary supplement raw material manufacturer y cosmetic raw material supplier bulk, we guarantee quality and consistency. Contact us today to discuss your specific requirements.

Contáctenos ahora para especificaciones técnicas y muestras:

Referencias:

  1. Comisión de la Farmacopea China. (2020). Epimedium Monograph

  2. Journal of Ethnopharmacology. (2021). Therapeutic Applications of Icariin

  3. FDA. (2023). Dietary Supplement Ingredient Directory

  4. European Medicines Agency. (2022). Herbal Medicine Compendium

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