Ganoderma Lucidum Polysaccharides
Ganoderma Lucidum Polysaccharide - Imagen 2
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Polisacárido de Ganoderma lucidum

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. Nombre en inglés: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Especificación
    • Contenido de polisacáridos: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Solubilidad: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Humedad: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Metales pesados: ≤ 10 ppm (totally safe for oral use—meets strict food/wellness standards)
    • Pureza: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Apariencia: Light yellow to off-white powder with a mild, earthy mushroom smell—definitivamente no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. N.º CAS.: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Plazo de entrega: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Paquete: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Mercado principal: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Escenarios de aplicación

Características principales

  • El “superpoder” del Reishi: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Mezcla versátil: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Natural y limpio: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Almacenamiento estable: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Aplicaciones industriales

  1. Suplementos dietéticos
    • Cápsulas/polvos de Reishi: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • Fórmulas de apoyo inmunitario: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Alimentos y bebidas funcionales
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Productos tradicionales de bienestar
    • TCM Formulations: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Specialty Nutrition
    • Bienestar para personas mayores: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Productos veganos/de origen vegetal: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness
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Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. What Are Ganoderma Lucidum Polysaccharides?

Ganoderma lucidum polysaccharides (GLPs) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Reishi mushroom). Structurally, they comprise β-(1→3)-D-glucan backbones con β-(1→6)-D-glucosyl branches, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1,000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.

2. Suministro, propiedades químicas y especificaciones técnicas

Fuentes botánicas y extracción

  • Main Supply: Fruiting our bodies of Ganoderma lucidum o G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Estrategias de extracción:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ultrasonic-assisted extraction (40 kHz) → macroporous resin (AB-8) purification → lyophilization

Chemical Identification

Propiedad Valer
N.º CAS Not assigned (advanced combination)
Fórmula molecular (C₆H₁₀O₅)ₙ
Peso molecular 10–1,000 kDa
EINECS Not relevant
Apariencia Mild brown hygroscopic powder
Solubilidad Water-soluble; insoluble in ethanol
Key Bioactivity β-(1→3)/(1→6) glycosidic bonds ≥85%

3. Beneficios para el bienestar, dosis óptima y seguridad

Resultados terapéuticos validados

  • Inmunomodulación:

    • ↑ Macrophage phagocytosis by 300% and ↑ NK cell cytotoxicity by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • Induce apoptosis in HepG2 cells (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Regulación metabólica:

    • ↓ Fasting blood glucose by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoprotección:

    • Reduce ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Sugerencias de dosificación

  • Bienestar general: 100–300 mg/day (20–30% GLPs)

  • Uso terapéutico:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Umbral de seguridad: ≤3,000 mg/day (no noticed toxicity)9.

Vital Precautions

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Procedimiento quirúrgico: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Interacciones farmacológicas: Might potentiate immunosuppressants (e.g., cyclosporine).

4. Firm Introduction: Shaanxi Zhonghong Biotechnology Co., Ltd.

A 28-year pioneer in bioactive polysaccharide manufacturing, Shaanxi Zhonghong integrates proprietary extraction tech with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Capacidades principales:

  • Extracción protegida por patente: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Rigor analítico: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain >99,5% pureza (exceeding USP/EP monographs).

  • Cumplimiento internacional:Certificaciones ISO 9001, FDA-GMP, EFSA, JECFA.

  • Proporcionar dominio de la cadena:Logística de cadena de frío en más de 80 países.

5. Product Specs: Pharmaceutical-Grade GLP QC

Contaminant Testing Requirements

Clase Parámetro Restringir Técnica de comprobación
pesticidas Clorpirifos ≤0,01 ppm GC-MS/MS (UE 396/2005)
Glifosato ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Metales pesados Plomo (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsénico (As) ≤0,5 ppm AAS (EP 2.4.27)
Microbiología Depende del plato entero ≤1.000 UFC/g USP <61>
E. coli Ausente ISO 16654
Salmonela especies Ausente FDA BAM Cap. 5

6. Flujo de trabajo de fabricación superior

  1. Abastecimiento: Natural G. lucidum fruiting our bodies (OOP-certified).

  2. Extracción: Dynamic maceration (95°C, pH 6.8, 3h) → ultrafiltration (100 kDa MWCO).

  3. Deproteinization: Sevag reagent (chloroform:butanol 4:1).

  4. Purificación: DEAE-Sepharose FF chromatography → lyophilization.

  5. Normalización: Phenol-sulfuric acid assay to 40% GLP content material.

7. Propósitos en todas las industrias

  • Nutracéuticos: Immune-boosting capsules (GLP + β-glucan synergy).

  • Medicamentos recetados: Chemotherapy adjuvants (reduces cisplatin nephrotoxicity).

  • Cosmecéuticos: Anti-aging serums (↑ collagen synthesis by 200%).

  • Useful Meals: Glycemic management drinks (GLP + berberine).

8. Gestión de alta calidad: Protocolo de garantía de 360°

GLP batches bear verificación de cuatro fases:

  1. Afirmación de identificación: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,070 cm⁻¹ C-O-C).

  2. Cuantificación de la pureza: HPSEC-ELSD (ICH Q2(R1)-validated; LOD: 0.05%).

  3. Prueba de bioactividad:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • α-Glucosidase inhibition: IC₅₀ ≤ 2 mg/mL

  4. Estabilidad: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).

9. Análisis de fronteras y desafíos

  • Perspectivas mecanicistas:

    • Intestine microbiota modulation (↑ Bifidobacteria ↑ SCFA manufacturing).

    • STING pathway activation for antitumor immunity.

  • Medical Translation:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Technical Boundaries:

    • Biodisponibilidad oral: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Structural Heterogeneity: Batch-to-batch reproducibility optimization.

  • Sostenibilidad:

    • Mycelial fermentation to preserve wild Ganoderma populations.

10. Preguntas frecuentes: Soluciones especializadas

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

P: ¿Tiempo óptimo de consumo?
A: Morning on empty abdomen (enhances macrophage uptake).

The place to Purchase Pharmaceutical-Grade GLPs

🔬 Orden directa de Shaanxi Zhonghong:

Conclusión

Ganoderma lucidum polysaccharides redefine precision immunonutrition—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!

Referencias:

  1. Revista de Etnofarmacología (2019). GLP mechanisms in most cancers apoptosis9.

  2. Polímeros de carbohidratos (2020). Structural characterization of immunomodulatory GLPs6.

  3. Química de las comidas (2021). Ultrasonic-microwave extraction optimization3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Frontiers in Immunology (2024). STING pathway activation by GLPs.

1 valoración en Ganoderma lucidum polysaccharide

  1. Avatar De James Oli***
    Valorado en 4 de 5

    James Oli*** –

    “As a health care product brand, aiherba.com’s ODM solution gives us peace of mind. They provide complete raw material traceability files. For example, the latest batch of Ganoderma lucidum triterpenoid extract can be traced from the planting to the extraction process of the organic base in Yunnan. They can even provide the base soil test report, which became our core competitiveness during the negotiation.”

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