Adenina

Adenine: Premium Manufacturer & Global Supplier for Pharmaceutical and Nutraceutical Applications | Aiherba

Source high-purity Adenine from Zhonghong, a leading fabricante y proveedor a granel. Essential nucleic acid base for pharmaceuticals and supplements. Solicitar una muestra gratuita y obtener una competitividad precio cita.

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1. What is Adenine?

Adenine is a fundamental purine derivative, one of the four core nucleobases that form the building blocks of DNA and RNA. It is a crucial component of adenosine triphosphate (ATP), the primary energy currency of the cell, and various cofactors like NAD and FAD. Beyond its biological role, adenine is a key starting material and intermediate in the synthesis of numerous antiviral and anticancer drugs. For B2B clients in the pharmaceutical, nutraceutical, and research sectors, a reliable Adenine manufacturer is essential for sourcing a high-purity, compliant ingredient that meets strict quality standards for critical applications.

2. Fuente, propiedades químicas e identificadores

• Fuente del producto: Primarily produced through chemical synthesis from simpler precursors like formamide or aminoimidazole carbonitrile (AICN) under controlled industrial conditions. This ensures high purity, consistency, and scalability.

• Clasificación química: Purine base.

• Número CAS: 73-24-5

• Fórmula molecular (MF): C5H5N5

• Peso molecular (PM): 135.13 g/mol

• EINECS: 200-796-1

3. What Defines the Best Adenine? A B2B Buyer’s Guide

Para internacional pharmaceutical companies, supplement exportadores, and research institutions, the “best” Adenine is defined by its ultra-high purity, low impurity profile (especially for related substances like other nucleobases), and comprehensive documentation supporting its intended use (e.g., DMF, CEP).

• Ingrediente clave y eficacia: Premium Adenine is a synthetic compound of high purity (e.g., ≥99.0% or USP/EP grade). Its primary roles are structural and functional:

  • Intermedio farmacéutico: A critical building block in the synthesis of nucleoside analogue drugs (e.g., Acyclovir, Tenofovir) used to treat viral infections and cancers.

  • Cell Culture Media Component: Used in biopharmaceutical manufacturing as a key nutrient for cell growth and proliferation.

  • Research Reagent: Essential for molecular biology research, PCR, and genetic studies.

  • (Compliant for use as a pharmaceutical intermediate, in cell culture, and as a research chemical. Not typically sold as a direct dietary supplement ingredient.)

• Origen y calidad: Our Adenine is synthesized in cGMP-compliant facilities, ensuring a product free from biological contaminants and with a consistent, well-defined chemical profile.

• Uso y dosis:

  • Uso típico: Incorporated as an active pharmaceutical ingredient (API) intermediate, a raw material in cell culture media, and a reagent in diagnostic kits and research laboratories.

  • Dosis recomendada: There is no standard dietary dosage. All usage is highly specific to the pharmaceutical synthesis protocol, cell culture formulation, or research application.

• Público aplicable: Pharmaceutical synthesis departments, biopharmaceutical companies, research institutions, and diagnostic kit manufacturers.

• Notas y efectos secundarios:

  • Precauciones: FOR INDUSTRIAL AND RESEARCH USE ONLY. Not intended for direct human consumption as a dietary supplement. Handle with appropriate personal protective equipment (PPE) in a laboratory setting.

  • Efectos secundarios: Not applicable for this B2B context. As a pharmaceutical intermediate, its safety profile is managed within the drug development process.

4. Why Partner with Zhonghong (Aiherba) as Your Adenine Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (Marketing global: Aiherba) es una empresa de alta tecnología certificada y de confianza exportador specializing in the synthesis and purification of high-value chemical and biochemical compounds for the global B2B mercado.

• Excelencia científica: Our joint laboratories with 5 leading universities and portfolio of 20+ patents allow us to optimize synthetic pathways for high yield, purity, and minimal environmental impact.

• Control de calidad inigualable: Our investment in advanced equipment like HPLC and Superconducting NMR ensures our purity standards meet or exceed USP, EP, and JP monograph requirements, which is critical for pharmaceutical applications.

• Red B2B global: With 28 years of experience in fine chemicals, we supply personalizado ingredientes y al por mayor quantities to multinational pharmaceutical corporations, al por mayor distributors, and premier research institutions across 80+ countries.

• Soporte regulatorio: We provide comprehensive documentation packages, including C of A, MSDS, and can support regulatory filings, making us a strategic partner for the pharmaceutical industry.

5. Especificaciones detalladas del producto (COA)

Every batch is accompanied by a comprehensive Certificate of Analysis (COA) that confirms compliance with stringent pharmacological standards.

6. Proceso de producción y control de calidad

Our production of Adenine involves multi-step chemical synthesis from validated starting materials. The process typically begins with precursors like formamide or AICN, undergoing a series of controlled reactions (e.g., cyclization, purification) to build the purine ring structure. The crude product is then purified through techniques such as recrystallization from a suitable solvent or chromatography to achieve the desired pharmaceutical-grade purity. The final product is dried and milled to a consistent particle size if required.

Nuestro Control de calidad is exceptionally rigorous and designed for pharmaceutical intermediates. It starts with qualifying all raw materials. In-process controls (IPC) are implemented at critical steps to monitor reaction completion and impurity profiles. The final product undergoes exhaustive testing. Cromatografía líquida de alta resolución (HPLC) with UV detection is the primary method for quantifying the Adenine content and profiling related substances and impurities. ICP-MS is used for sensitive heavy metal detection. Titulación de Karl Fischer precisely measures water content. Additionally, we perform microbiological testing to ensure bioburden limits are met. This multi-tiered QC protocol, conducted in our state-of-the-art labs, guarantees a product that is consistent, pure, and suitable for its demanding applications.

7. Escenarios de aplicación

Adenine is a critical ingredient for advanced industries:

• Productos farmacéuticos: Primarily used as a key intermediate in the synthesis of a wide range of antiviral and anticancer nucleoside analogue drugs.

• Biopharmaceuticals: An essential component of defined cell culture media used in the production of monoclonal antibodies, vaccines, and other biologics.

• Molecular Biology & Diagnostics: Used as a raw material in PCR kits, nucleotide synthesis, and various research reagents.

• Chemical Research: Serves as a building block for novel chemical entities and materials science research.

8. Rol técnico, investigación e innovación

Adenine’s role is structural and functional, serving as a core scaffold in nucleic acids and critical biomolecules. The main research frontier involves developing more efficient and greener synthetic routes for its production and creating novel derivatives with enhanced biological activities. The key desafío for manufacturers is achieving and consistently maintaining ultra-high purity with minimal isomeric and other purine impurities, which is crucial for pharmaceutical efficacy and safety. At Zhonghong, our innovación lies in our patented, optimized synthesis pathways that maximize yield and purity while reducing environmental impact, providing our B2B partners with a reliable and high-quality building block for their most important products.

9. FAQ – Preguntas frecuentes

Q: What is the Minimum Order Quantity (MOQ) for pharmaceutical grade?
A: MOQs vary based on the specific grade and packaging. We cater to both large-scale al por mayor orders for production and smaller R&D quantities. Contact us for details.

Q: Can you provide Adenine that complies with USP/EP/JP monographs?
A: Yes, we can supply Adenine that meets the specifications of various international pharmacopoeias. Please specify your required standard when inquiring.

Q: Do you offer custom synthesis for Adenine derivatives?
A: Sí, nos especializamos en extracto de hierbas personalizado and chemical solutions. Our R&D team can collaborate on the synthesis of specific purine derivatives. Inquire for feasibility.

Q: Do you offer samples for our quality testing and R&D?
A: Por supuesto. Ofrecemos muestra gratis materials to qualified businesses and research institutions for evaluation and testing purposes.

Q: What documentation do you provide for pharmaceutical customers?
A: We provide a comprehensive suite including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and can provide supporting data for Drug Master Files (DMF) as required.

10. Dónde comprar y solicitar muestras gratuitas

Como empresa líder fabricante y proveedor global of fine chemicals and pharmaceutical intermediates, we are your trusted partner for sourcing high-purity Adenine.

Contact us today to discuss your procurement needs, request a free sample for your QA/QC, and get a competitive wholesale price.

• Correo electrónico: ventas@aiherba.com / liaodaohai@gmail.com

• Sitio web: www.aiherba.com

11. Conclusión

Para B2B clients in the pharmaceutical and life science industries, Adenine is a fundamental, non-negotiable building block. Choosing a supplier with robust synthetic capabilities, uncompromising quality control aligned with pharmacopoeial standards, and proven internacional regulatory support is paramount. Zhonghong (Aiherba) provides not just a chemical, but a reliable partnership, offering a premium, thoroughly documented product that integrates seamlessly into your critical workflows, backed by decades of experience in chemical manufacturing.

12. Referencias

• USP/EP/JP Monographs for Adenine.

• Journal of Medicinal Chemistry: Studies on the synthesis and application of purine derivatives in drug discovery.

• Organic Process Research & Development: Publications on the industrial synthesis and optimization of nucleobases.

• ICH Guidelines (Q3A, Q7) for impurities in new drug substances and Good Manufacturing Practice.