Pure Fish Collagen Powder: Premium Marine Sourcing from Zhonghong Biotech (Free Samples Available)
1. What is Pure Fish Collagen Powder?
Pure Fish Collagen Powder, predominantly Type I collagen, is a hydrolyzed protein derived from the skin, scales, and bones of marine fish (e.g., Tilapia, Cod). This enzymatic hydrolysis process yields bioactive péptidos de colágeno – low molecular weight fragments (typically 2,000-5,000 Da) with significantly enhanced biodisponibilidad compared to native collagen. These peptides are rapidly absorbed into the bloodstream via the paracellular pathway y PepT1 transporter, facilitating targeted delivery to skin, joints, and connective tissues to stimulate endogenous collagen synthesis via fibroblast activation and modulation of TGF-β/Smad signaling pathways. Its superior solubility, neutral taste, and odorless profile make it ideal for nutraceutical and functional food applications.
2. Origen del producto, propiedades químicas e identificación
Fuente: Sustainably sourced Marine Fish (Tilapia nilotica, Gadus morhua). Traceability protocols ensure origin compliance.
Número CAS: 9007-34-5
Fórmula molecular (MF): Represents repeating amino acid sequences (primarily Gly-X-Y, where X & Y are often Pro and Hyp).
Peso molecular (PM): Hydrolyzed form: Typically 2,000 – 5,000 Daltons (Da).
EINECS: 232-697-4
Propiedades químicas clave: High solubility (><|begin▁of▁thinking|> pH stability, rich in Glycine (~33%), Proline (~12%), Hydroxyproline (~10%) – crucial for triple-helix stability and biological activity. Exhibits characteristic FT-IR spectra (Amide I, II, III bands) and DSC thermograms.
3. Why Zhonghong Biotech’s Pure Fish Collagen is the Optimal Choice
Zhonghong Biotech sets the benchmark for premium Pure Fish Collagen Powder through rigorous science and quality:
Premium Ingredients: 100% pure hydrolyzed fish collagen peptides. Non-GMO, Gluten-Free, Allergen-Free (BSE/TSE Free). No fillers or artificial additives.
Clinically Validated Efficacy (Compliant): Supports skin dermal matrix integrity (increases elasticity, reduces wrinkles – in vivo studies), promotes chondrocyte proliferation y synovial fluid viscosity for joint comfort, enhances bone mineral density (Osteoblast stimulation), aids muscle protein synthesis (MPS), and supports gut mucosal barrier function.
Ingesta diaria óptima: Recommended dosage: 5g to 10g daily. Efficacy supported by clinical research (e.g., Proksch et al., 2014). Consult a physician for specific needs.
Origen y fabricación: Sourced responsibly, processed in cGMP-certified facilities in China. Advanced enzymatic hydrolysis ensures optimal peptide profile.
Uso: Easily soluble in hot/cold beverages, smoothies, yogurts, or baked goods. Ideal for capsules, tablets, and functional foods.
Público objetivo: Adults seeking skin health, joint support, athletes, seniors, individuals in wellness programs.
Seguridad y efectos secundarios: Generally Recognized As Safe (GRAS). Well-tolerated. Potential mild gastrointestinal discomfort if taken in excessive doses initially.
Consideraciones críticas: Verify Declaraciones de alérgenos (fish source), ensure product has full Certificado de análisis (CoA) confirming purity and safety (see below). Contraindicated for individuals with severe fish allergies.
4. Zhonghong Biotech: Your Trusted Collagen Partner
Zhonghong Biotech (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a globally recognized leader in the research, development, and large-scale manufacturing (Bulk Supplier) of high-purity bioactive compounds. With 28 años of expertise in extracción de plantas y marine bioactives, we serve the chemical, material science, and life science sectors.
Proeza científica: Collaboration with 5 universidades de élite fuels our Más de 20 tecnologías patentadas and exclusive biblioteca global de compuestos, creating significant R&D barriers.
Infraestructura de vanguardia: Equipado con HPLC (cromatografía líquida de alta resolución), UHPLC-MS (Ultra-HPLC-Mass Spectrometry), y 600MHz Superconducting NMR (Nuclear Magnetic Resonance). Our purity standards exceed industry norms by 20%+.
Global Supply Chain Excellence: Our robust network delivers extracto de hierbas personalizado and bioactive solutions to más de 80 países, serving multinational pharmaceutical companies, leading nutraceutical brands (Wholesale partners), and premier research institutions. We specialize in soluciones personalizadas tailored to specific application requirements.
5. Comprehensive Product Specifications & Certificate of Analysis (CoA)
Zhonghong guarantees transparency. Every batch undergoes stringent testing per international pharmacopeia (USP, EP).
Pure Fish Collagen Powder – Certificate of Analysis (CoA) Summary
Test Category | Parámetro | Especificación | Método de prueba |
---|---|---|---|
Pesticides (Agricultural Residues) | |||
Clorpirifos | ≤ 0,01 mg/kg | GC-MS/MS (EN 15662) | |
Diclorvos | ≤ 0,01 mg/kg | GC-MS/MS (EN 15662) | |
Cipermetrina | ≤ 0,05 mg/kg | GC-MS/MS (EN 15662) | |
Total de pesticidas | Meet USP <561> / EP 2.8.13 | Multi-Residue GC-MS/MS/LC-MS/MS | |
Metales pesados | |||
Plomo (Pb) | ≤ 0,5 mg/kg | ICP-MS (USP <232> / EP 2.4.8) | |
Arsénico (As) | ≤ 0,5 mg/kg | ICP-MS (USP <232> / EP 2.4.8) | |
Cadmio (Cd) | ≤ 0,1 mg/kg | ICP-MS (USP <232> / EP 2.4.8) | |
Mercurio (Hg) | ≤ 0,1 mg/kg | CV-AAS / ICP-MS (USP <232>) | |
Microbiológico | |||
Recuento total de placa | ≤ 1.000 UFC/g | USP <61> / EP 2.6.12 | |
Levadura y moho | ≤ 100 UFC/g | USP <61> / EP 2.6.12 | |
Escherichia coli | Ausente en 1g | USP <62> / EP 2.6.13 | |
Especies de Salmonella. | Ausente en 25g | USP <62> / ISO 6579-1 | |
Estafilococo áureo | Ausente en 1g | USP <62> / EP 2.6.13 | |
General | Apariencia | Fine, white to off-white powder | Visual |
Identification (FT-IR) | Conforms to Reference Standard | USP <197> / EP 2.2.24 | |
Protein Content (N x 6.25) | ≥ 90.0% | Kjeldahl / Dumas (USP <841>) | |
Hydroxyproline Content | ≥ 8.0% | HPLC (ISO 3496) | |
Humedad | ≤ 8.0% | Karl Fischer (USP <921>) | |
Ceniza | ≤ 2.0% | USP <281> | |
pH (1% Solution) | 5.5 – 7.0 | Potentiometric (USP <791>) | |
Particle Size (95% Pass) | ≤ 80 mesh | Sieve Analysis (USP <786>) |
6. Advanced Production Process: Precision Hydrolysis
Our optimized manufacturing ensures peak bioactivity:
Sustainable Sourcing & Prep: Raw fish by-products undergo rigorous veterinary inspection and controlled trimming/washing.
Demineralization & Defatting: Acid/alkali treatment removes minerals and lipids.
Enzymatic Hydrolysis: Specific proteolytic enzymes (e.g., Alcalase, Trypsin) cleave collagen under controlled T/pH/duration to yield target peptide profiles (<5kDa).
Purificación de múltiples etapas: Filtration (ultrafiltration/nanofiltration), ion-exchange, and activated carbon remove impurities, odors, and salts.
Esterilización y secado: Terminal sterilization (where applicable) followed by secado por aspersión (inlet/outlet temp control) or liofilización para máxima estabilidad.
Strict QC Release: Comprehensive testing per CoA specifications before packaging.
7. Diversos escenarios de aplicación
Nutracéuticos: Capsules, tablets, stick packs, gummies for skin beauty, joint health, sports nutrition.
Alimentos y bebidas funcionales: Fortified protein drinks, dairy products, health bars, confectionery.
Cosmecéuticos: Key active in anti-aging serums, creams, masks for dermal rejuvenation y moisture retention.
Medical Nutrition: Supports tissue repair and wound healing formulations.
Pet Nutrition: Joint and coat health supplements.
8. Rigorous Quality Control (QC) Protocol
Zhonghong’s QC is integrated throughout the product lifecycle. Starting from Cumple con las normas GMP raw material qualification (vendor audits, CoA review), we implement Process Analytical Technology (PAT) for real-time monitoring of critical parameters (pH, temp, peptide size via GPC/SEC) during hydrolysis. Our state-of-the-art Quality Control Laboratory, equipado con HPLC-DAD/ELSD/RID, ICP-MS, GC-MS/MS, UHPLC-QTOF-MS, y Microbiological suites, performs identity, purity, potency, and safety testing per validated methods aligned with ICH Q2(R1). Stability studies (ICH Q1A) ensure shelf-life. Trazabilidad de lotes is enforced. Our ISO 9001:2015 y ISO 22000/FSSC 22000 certified systems guarantee consistent, safe, high-quality Colágeno puro de pescado en polvo meeting global regulatory standards (FDA, EFSA, Health Canada).
9. Embalaje seguro y logística global
Embalaje: Available in multi-layer foil bags (1kg, 5kg, 10kg) with desiccant, inside food-grade bidones de HDPE (25kg) or tambores de fibra (20kg). Custom packaging for a granel orders. Nitrogen flushing optional.
Almacenamiento: Store in a cool (<25°C), dry place. Shelf life: 24 months unopened.
Logística: Efficient global shipping via air/sea freight. Expertise in export documentation and cold chain (if required). Compliant with IATA/IMDG regulations.
10. Deep Dive: Health Mechanisms, Applications & Innovation
Mecanismos de salud: Bioactive peptides (e.g., Pro-Hyp, Gly-Pro-Hyp) act as ligands for receptors on fibroblasts/chondrocytes, stimulating collagen I/III, elastin, y hyaluronic acid synthesis a través de MAPK/ERK y PI3K/Akt pathways. Exhibit antioxidante activity (radical scavenging), MMP inhibition, and modulate inflammatory cytokines (e.g., TNF-α, IL-1β).
Aplicaciones industriales: Driving innovation in beauty-from-within supplements, osteoarthritis management, sarcopenia mitigation, wound healing biomaterials, y functional food fortification.
Research & Challenges: Current focus on structure-activity relationship (SAR) of specific peptides, bioavailability enhancement (nano-delivery), sustainable sourcing (by-product valorization), and clinical validation for new indications (gut-brain axis, metabolic health). Challenges include standardization of bioactive peptide profiles and large-scale cost-effective production of specific sequences.
11. Preguntas frecuentes (FAQ)
Q1: What makes marine collagen better than bovine/porcine?
A1: Marine collagen (Type I) boasts superior biodisponibilidad due to lower molecular weight peptides and is preferred for ethical/religious (halal/kosher potential) and safety (BSE-free) reasons. Often perceived as more sustainable.
Q2: How long to see results?
A2: Clinical studies show visible skin improvements (hydration, elasticity) often within 4-8 weeks of consistent use (5-10g/day). Joint benefits may take 8-12 semanas.
Q3: Is it safe during pregnancy/breastfeeding?
A3: Generally safe, but consult your physician before starting any new supplement.
Q4: Can vegetarians/vegans use this?
A4: No, as it’s derived from fish. Plant-based collagen boosters exist but do not provide direct collagen peptides.
Q5: Do you offer free samples?
A5: Yes! We provide muestra gratuita de extracto de hierbas of our Pure Fish Collagen Powder for qualified businesses. Contact us to request.
Q6: What customization options are available?
A6: Ofrecemos extracto de hierbas personalizado solutions including specific peptide profiles (molecular weight distribution), flavor masking, instantization, and blends with other actives (e.g., Vitamin C, Hyaluronic Acid). Discuss your customized needs.
Q7: What is the minimum order quantity (MOQ)?
A7: Competitive MOQs for a granel y al por mayor quantities. Contact sales for specific details based on your requirements.
Q8: Where can I buy?
A8: Contact Zhonghong Biotech directly for a granel, al por mayor, y Fabricante de equipos originales (OEM) inquiries. Visit our website for more information.
12. Where to Buy & Request Free Samples
Ready to source premium Colágeno puro de pescado en polvo? As a leading fabricante y proveedor, Zhonghong Biotech offers competitive precios para a granel quantities and al por mayor partnerships.
Get Your Free Sample: Experience the Zhonghong quality difference. Qualified businesses can request muestra gratuita de extracto de hierbas.
Contáctenos:
Correo electrónico: ventas@aiherba.com, liaodaohai@gmail.com
Sitio web: www.aiherba.com
Enfoque de la investigación: Bulk Orders, Wholesale Pricing, Customization, Free Samples, OEM/ODM Services.
13. Conclusión
Colágeno puro de pescado en polvo represents a scientifically substantiated bioactive ingredient for enhancing skin, joint, and overall connective tissue health. Zhonghong Biotech apalancamientos 28 años of expertise in bioactive extraction and purification, cutting-edge analytical technology (HPLC, NMR, MS), and a global distribution network to deliver a premium, high-purity, traceable marine collagen peptide product. Our commitment to control de calidad exceeding industry standards, personalización capabilities, and provision of muestras gratis establishes us as the trusted partner for nutraceutical brands, functional food developers, and al por mayor distributors worldwide. Contact us today to discuss your collagen sourcing needs and explore partnership opportunities.
14. Referencias
Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.
León-López, A., et al. (2019). Hydrolyzed Collagen—Sources and Applications. Moléculas, 24(22), 4031.
Khatri, M., et al. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino Acids, 53(10), 1493-1506.
Song, H., et al. (2022). Bioactive collagen peptides: a review of their generation, bioactivities and applications. Revista de alimentos funcionales, 88, 104909.
ISO 3496:1994. Animal and vegetable fats and oils — Determination of hydroxyproline content.
USP-NF General Chapters: <61> Microbiological Examination, <232> Elemental Impurities, <561> Articles of Botanical Origin, <197> Spectrophotometric Identification Tests.
European Pharmacopoeia (Ph. Eur.) Monographs and General Chapters (e.g., 2.4.8 Heavy metals, 2.6.12/13 Microbiological examination).
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