Versicolor Psk
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PSK versicolor

Versicolor PSK supplier bulk factory Wholesale Extract factory

  1. Nombre en inglés: Polysaccharide – De acuerdo (PSK), También conocido como Krestin
  1. Especificación
    • Común Polvo: PSK ≥ 95% (HPLC), molecular weight redondo 100 kDa
    • Water – soluble Tipo: Extremadamente soluble en agua, formando una capa clara opciones; PSK contenido material ≥ 90% in water – soluble formulations, with correcto solubility – enhancing corredores
  1. Apariencia
    • Polvo: Leve – brown to off – white enorme powder, odorless or with a faint, earthy scent
    • Water – soluble Tipo: Claro a apenas yellowish liquid
  1. N.º CAS.：65963 – 10 – 0
  1. Plazo de entrega: 5 – 10 días laborables
  1. Paquete
    • 1 kg/bag (aluminum foil bag), 5 kg/drum (sterilized stainless – metal drum with vacuum seal for pharmaceutical – grade mercancías); 25 kg/drum (double – layer PE bag inside cardboard drum for industrial – grade mercancías)
  1. Mercado principal: Asia (Japan, China, South Korea), North America, Europe
  1. Escenarios de aplicación

Propiedades principales

  • Molecular Construcción: A protein – certain polysaccharide, composed of a β – glucan columna vertebral with β – 1,4 importante chains and β – 1,3 and β – 1,6 aspect chains. The protein parte es hooked up to the β – 1,6 aspect chains.
  • Solubilidad: Soluble in water, which es útil para numeroso propósitos, particularmente in pharmaceutical and nutraceutical formulations.
  • Llave Opciones
    • Inmunomodulador: Potently modulates the immune system by activating macrophages, T – lymphocytes, and puro killer cells. It helps the immune system to raised acknowledge y meta irregular cells, similar a cáncer cells, mientras además parada over – activation that might producir autoimmune – like reactions.
    • Adyuvante antitumoral: Has probado importante adjuvant anti – tumor ejercicio in vitro and in vivo en oposición a numeroso cancers, junto con colorectal, gastric, breast, liver, pancreatic, and lung cáncer. It really works juntos with chemotherapy and radiotherapy, enhancing their efficacy and decreciente aspect – resultados.
    • Antioxidante: Elimina los radicales libres, defendiendo células de la oxidación lesión, que es relacionado con envejeciendo, irritación, y numeroso enfermedades.
    • Baja toxicidad: Generalmente bien – tolerated by the human físico, with minimal aspect – resultados, haciéndolo adecuado para largo – período de tiempo uso en bienestar – venta and therapeutic propósitos.

Escenarios de aplicación

1. Medicamentos recetados

  • La mayoría de los cánceres Recurso:
    • Auxiliar Recurso: Extensamente utilizado en Japan as an adjuvant immunotherapy for un numero de cancers. Together con quimioterapia medicamento (similar a 5 – fluorouracil for colorectal cáncer), it might probably mejorar recurso resultados. Médico investigación tener probado eso it might probably mejorar the survival precio de cáncer pacientes, mejorar su alta calidad of life, and reducir la escala chemotherapy – induced immunosuppression.
    • Inmune Ayuda:Ayuda cáncer pacientes preservar a sano immune system a lo largo de recurso, decreciente la oportunidad of infections and diferente problemas. Por ejemplo, in non – small cell lung carcinoma pacientes proceso actual radiotherapy, PSK supplementation can mejorar inmune llevar a cabo y reducir la escala the severity of radiation – induced aspect – resultados.
  • Hígado Seguridad:
    • Investigación have demonstrated that PSK can defender the liver from lesión, similar a eso provocado por alcohol. Podría reducir la escala the degrees of liver – llevar a cabo markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in alcohol – induced liver dañar modas, suggesting its potential use in liver – defendiendo medicamentos.

2. Nutracéuticos

  • Immune – boosting suplementos dietéticos:
    • Allá afuera in capsule, píldora, or powder amable dentro de la nutraceutical market. Clientes can take it cada día to strengthen their immune métodos, particularmente a lo largo de seasons when la oportunidad of infections is excesivo. It is usually adecuado para individuos with weakened immune métodos debido a continuo enfermedades o envejeciendo.
  • Práctico Comidas:
    • Integrado en útil comidas como vitalidad bars, yogurt, and bebidas. A modo de ilustración, alguno bienestar – dirigido yogurt mercancías comprender PSK suministrar compradores con an extra immune – boosting ganancia junto con el dietético valer del comidas.

3. Productos cosméticos

  • Anti – envejeciendo Mercancías:
    • Added to serums, lociones, and masks for its antioxidant and immunomodulatory properties. Podría asistir reducir la escala las miradas de enorme rastros and wrinkles by defendiendo poros y piel cells from oxidative stress and venta a sano poros y piel immune response.
  • Poros y piel – Soothing Formulations:
    • En mercancías designed for delicado or irritated poros y piel, PSK’s anti – inflammatory properties Podría ayudar calm the poros y piel, reducir la escala redness, and promote poros y piel restaurar.

Detección Estrategias

  • Excesivo – Eficiencia Cromatografía líquida (HPLC):
    • Column: An acceptable carbohydrate – evaluación column (e.g., TSKgel GMPWXL, 300 × 7.8 mm). Celúla Sección: A combination of solvents like 0.7% sodium sulfate resolución. Circular Cargar: 0.6 – 1.0 mL/min. Detection es usualmente llevado a cabo utilizando a refractive index detector or an evaporative leve – scattering detector to precisamente quantify PSK contenido material.
  • Gel Permeation Chromatography (GPC):
    • Usado Para averiguarlo the molecular weight distribution of PSK. It separates the polysaccharide molecules basado principalmente en su dimensión, ofrenda detalles sobre the typical molecular weight and the polydispersity index.
  • Immunological Assays:
    • ELISA (Enzyme – Linked Immunosorbent Assay) – basado principalmente estrategias Podría ser developed to particularmente detect PSK, profiting from its protein – certain nature. Antibodies en oposición a PSK se puede utilizar a seize and detect the polysaccharide in samples, which es útil para alta calidad gestión in product manufacturing.

Suministrar & Beneficios

  • Natural Suministrar: Extracted from the mycelium of Trametes versicolor, un estándar basidiomycete mushroom También conocido como turkey tail. It has una prolongada historia de uso en convencional asiático drogas, particularmente in China and Japan, courting de nuevo to the Ming Dynasty (1368 – 1644).
  • Scientific Validation: In depth científico análisis, junto con in – vitro and in – vivo investigación, in addition to científico trials, has validated its immunomodulatory and antitumor properties. This scientific prueba ofertas Un poderoso base for its use in de moda drogas y bienestar mercancías.
  • Múltiples – útil Beneficios: Es habilidad to modulate the immune system, act as an antioxidant, and asistir numeroso elementos de bienestar lo hace un flexible ingrediente con propósitos a lo largo de completamente diferente industries, from medicamentos recetados to cosmetics.

Cumplimiento normativo

  • Japón: Permitido como fármaco adyuvante para cáncer recurso, with strict Good Manufacturing Follow (BPF) artículos de primera necesidad para fabricación. It has been used dentro de la Japanese healthcare system for many years, y su seguridad and efficacy are bien – established dentro de la context of cáncer auxiliar recurso.
  • China: Admitido como un precioso medicinal ingredient. Mercancías containing PSK desear Para satisfacer el normas del A escala nacional Médico Mercancías Administration (NMPA) for cada pharmaceutical and nutraceutical propósitos.
  • US and Europe: In the USA, PSK is regulated as a dietary complementar abajo the Dietary Complementar Bienestar y Schooling Act (DSHEA). In Europe, it falls abajo el normas for novel comidas y comidas suplementos dietéticos, con artículos de primera necesidad para seguridad evaluación and labeling.
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Versicolor PSK (Polysaccharide-Krestin): Premium Immune-Assist Ingredient for Nutraceutical & Pharmaceutical Purposes – Manufacturer Information

1. What is Versicolor PSK?
For product builders within the immune well being area, Versicolor PSK (Polysaccharide-Krestin) stands as a premier, clinically researched bioactive compound. It’s a proprietary protein-bound polysaccharide (β-glucan) extract derived from the deep-layer cultivated mycelium of the Trametes versicolor o Coriolus versicolor mushroom. In contrast to easy mushroom powders, PSK is a extremely refined, standardized extract with a well-documented historical past of use in supportive care, making it a high-value ingredient for classy nutraceutical and pharmaceutical formulations.

2. Suministro, química y especificaciones

  • Suministrar: Derived from the classy mycelium of Trametes versicolor (Turkey Tail mushroom).

  • Bioactivo clave: A protein-bound polysaccharide complicated, primarily β-glucans with a particular construction and molecular weight profile.

  • Perfil químico: As a fancy organic polymer, it doesn’t have a single CAS, MF, or MW. Its identification is outlined by its distinctive polysaccharide-protein composition and organic exercise.

  • Apariencia: Wonderful brownish powder with a attribute gentle, fragrant odor.

  • Solubilidad: Partially soluble in water, forming a colloidal answer.

3. The Formulator’s Alternative: Why Standardized PSK is Finest
Para B2B shoppers within the complement and wellness industries, not all mushroom extracts are created equal. Right here’s why standardized PSK is the benchmark:

  • Diferenciador clave: Standardization to particular polysaccharide content material (e.g., ≥ 30% or greater) ensures constant organic exercise and efficacy, which is important for reproducible product outcomes.

  • Confirmed Well being Benefits (Compliant Claims for Producers):

    • Modulación del sistema inmunológico: Helps and helps regulate wholesome immune operate.

    • Propiedades antioxidantes: Helps shield cells from oxidative stress.

    • General Wellness Assist: Promotes common well being and vitality.

    • (Notice: Particular illness claims are topic to drug approval in most areas and can’t be made for dietary dietary supplements).

  • Typical Use Degree: Medical research usually use doses from 1 to three grams per day of the purified extract. Formulation dosage must be decided primarily based on the specified efficiency of the ultimate product.

  • Origen y alta calidad: Produced beneath strict, managed fermentation situations to make sure purity, consistency, and absence of environmental contaminants.

  • Solicitud: Preferrred for capsules, tablets, and powdered drink formulations the place a potent, water-soluble extract is required.

  • Goal Industries & Formulations:

    • Nutracéuticos: Excessive-potency immune help dietary supplements, wellness formulation.

    • Comidas y bebidas con propósito: Fortified well being drinks and powders.

    • Cosmecéuticos: Skincare merchandise for its antioxidant advantages.

  • Security & Regulatory: Has an extended historical past of secure use. Usually well-tolerated. Minor uncomfortable side effects might embody gentle digestive upset.

4. Zhonghong Biotech: Your World Manufacturer & Export Accomplice
Sourcing a dependable, high-potency PSK supplier is a important choice. Tecnología de inversión Shaanxi Zhonghong Co., Ltd. is a licensed Fabricante y exportador with over 28 years of experience in superior extraction and fermentation expertise for the worldwide B2B market.

  • Competencia básica: We specialize within the cultivation, extraction, and purification of premium fungal and botanical bioactives. Our portfolio consists of:

    • Standardized Mushroom Extracts (PSK, PSP, Reishi, Cordyceps)

    • Elementos nutracéuticos

    • Lively Pharmaceutical Elements (APIs) & Intermediates

  • Why Worldwide Purchasers Select Us:

    • Excelencia científica: 20+ patents and collaborations with 5 main universities guarantee we’re on the forefront of mycological extraction expertise.

    • Gestión de alta calidad inigualable: Nuestra financiación en HPLC, HPTLC, and NMR spectroscopy ensures a purity and efficiency customary that constantly exceeds business specs.

    • World B2B Export Community: We’re a trusted Exportador a dietary complement, pharmaceutical, practical meals, and beauty industries in over 80 nations, providing tailor-made opciones de ingredientes personalizados.

5. Technical Perception: Mechanism of Motion
PSK’s main immunomodulatory results are attributed to its capability to bind to particular receptors on immune cells (e.g., dendritic cells, macrophages), enhancing their communication and response. This results in a extra coordinated and environment friendly immune exercise, which is the idea for its widespread use in supportive well being purposes.

6. Iron-Clad High quality Dedication: The COA
Our High quality Management is designed for regulatory compliance and buyer belief. Each batch is rigorously examined to satisfy stringent specs.

Certificates of Evaluation (COA) Abstract – Versicolor PSK

Clase Parámetro Especificación Técnica de comprobación
Ensayo Polisacáridos ≥ 30.0% UV-Vis / Phenol-Sulfuric Acid
β-Glucans ≥ 20.0% Enzymatic Technique
Metales pesados Plomo (Pb) ≤ 0,5 mg/kg ICP-MS
Arsénico (As) ≤ 0,5 mg/kg ICP-MS
Cadmio (Cd) ≤ 0,2 mg/kg ICP-MS
Mercurio (Hg) ≤ 0,1 mg/kg ICP-MS
Microbiología Confianza en el plato entero ≤ 5,000 CFU/g USP <61>
Levadura y moho ≤ 100 UFC/g USP <61>
E. coli Adverso en 1g USP <62>
Salmonela especies Adverso en 10 g USP <62>
Diferente Pérdida por secado ≤ 8.0% USP <731>
Disolventes residuales Cumple con ICH Q3C GC-FID

(A full, batch-specific COA is supplied with each cargo.)

7. Curso Superior de Manufactura de
Our cGMP-compliant course of ensures a superior, constant extract:

  1. Pressure Choice & Cultivation: Use of a proprietary, high-yield Trametes versicolor pressure cultivated in managed bioreactors.

  2. Fermentación: Optimized submerged fermentation to maximise biomass and bioactive manufacturing.

  3. Extracción: Sizzling water extraction beneath managed time and temperature to isolate the polysaccharide-protein complicated.

  4. Filtración y enfoque: Removing of insoluble matter and focus of the energetic extract.

  5. Purificación: Additional refinement steps to realize the goal polysaccharide focus.

  6. Secado por aspersión: Conversion right into a secure, fantastic powder.

  7. Standardization & QC: Exact mixing to ensure constant efficiency, adopted by full analytical testing.

8. Aplicación en formulaciones B2B
This ingredient is a cornerstone for superior immune and wellness merchandise:

  • Suplementos dietéticos: Capsules and tablets for immune help.

  • Comidas y bebidas con propósito: Fortified powders, well being drinks, and photographs.

  • Vitamina médica: Merchandise designed for supportive care.

  • Cosmecéuticos: Premium skincare serums and lotions.

9. B2B Packaging & World Export Logistics

  • Embalaje: 1 kg / 5 kg double-sealed luggage inside 25 kg fiber drums. Customized embalaje a granel accessible.

  • Almacenamiento: Retailer in a cool, dry, and well-ventilated place. Preserve container tightly sealed.

  • Duración: 24 months when saved beneath really helpful situations.

  • Logística: As an skilled Exportador, we deal with all worldwide transport, documentation (COA, MSDS, Certificates of Origin), and guarantee easy customs clearance.

10. Accomplice with Us for Your Bulk Ingredient Wants
Zhonghong Biotech is your strategic companion for high-purity, potent substances. We offer:

  • Aggressive Bulk Pricing: Obtenga un contacto directo manufacturing unit value Para pedidos de gran volumen.

  • Personalización y OEM: Nosotros proporcionamos personalizado extracts with various polysaccharide concentrations and blends.

  • Asistencia regulatoria: Documentation to help your product registrations.

Contact Us for a Quote or to Request a Pattern!

  • Neto: www.aiherba.com

  • Correo electrónico: ventas@aiherba.com; liaodaohai@gmail.com

  • Frases clave: Versicolor PSK supplier, bulk PSK, Polysaccharide-Krestin producer, purchase Trametes versicolor extract, wholesale mushroom extract, immune help ingredient supplier, extracto natural personalizado, pharmaceutical uncooked materials supplier.

11. FAQ for B2B Purchasers

  • P: ¿Cuál es su monto mínimo de pedido (MOQ)?
    A: Contact us for particular MOQ particulars. We provide versatile phrases for a granel y al por mayor compañeros.

  • Q: Are you able to present PSK with totally different polysaccharide standardizations?
    A: Sure. We will present technical steering and opciones personalizadas (e.g., 30%, 40%, 50% polysaccharides) primarily based in your formulation targets.

  • Q: Do you present full regulatory documentation for export?
    A: Completely. We offer a complete Certificates of Evaluation (COA), MSDS, and different needed export paperwork.

  • Q: What is the lead time for big orders?
    A: Lead instances differ primarily based on order measurement. We preserve strategic inventory and supply clear manufacturing timelines.

  • Q: How can we begin the qualification course of?
    A: E-mail us at ventas@aiherba.com Para solicitar una patrón gratuito and focus on your technical specs.

12. Conclusión
For manufacturers formulating within the aggressive immune well being market, standardized Versicolor PSK gives a confirmed, high-efficacy choice. Partnering with a technically superior, dependable Fabricante y exportador is important for guaranteeing ingredient high quality, provide chain safety, and last product integrity. Zhonghong Biotech, with its scientific experience, rigorous QC, and international export functionality, is the optimum companion for industrias nutracéuticas y farmacéuticas. Contact us immediately to debate your venture wants and request a pattern.

Referencias:

  • Standish, L.J., et al. (2008). Trametes versicolor mushroom immune remedy in breast most cancers. Journal of the Society for Integrative Oncology.

  • Kidd, P.M. (2000). Using mushroom glucans and proteoglycans in most cancers remedy. Various Drugs Overview.

  • Tsukagoshi, S., et al. (1984). Krestin (PSK). Most cancers Remedy Opinions.

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