Tocoferol-Vitamina E
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Tocoferol-Vitamina E

Tocopherol-Vitamin E supplier bulk factory buy Wholesale，

  1. Inglés Nombre: Tocopherol-Vitamin E
  1. Especificación
    • Pureza: ≥ 96% (HPLC for alpha – tocopherol)
    • Solubilidad: Virtually insoluble in water; extremadamente soluble in gordo, oils, and organic solvents correspondiente a ethanol (≥ 50 g/100 mL), propylene glycol
    • Mirar – asociado: Pérdida por secado ≤ 1,01 TP3T, Metales pesados ≤ 10 ppm, Disolventes residuales ≤ 0,51 TP3T
    • Amable: Podría ser dentro de la tipo de oil (enfocar típicamente 90 – 95% tocopherols), powder (micro – encapsulated for más alto stability, particle dimensión ≤ 100 μm)
  1. Mirar
    • Yellow to amber – coloured viscous oil (synthetic or natural aceite amable), or off – white to amable yellow free – flowing powder (micro – encapsulated amable), odorless or with a faint, atributo delicado olor, no asociado al chocolate
  1. N.º CAS.
    • Alpha – Tocopherol: 59 – 02 – 9; Normal Vitamin E (combined tocopherols): 1338 – 43 – 8
  1. Plazo de entrega: 5 – 7 días laborables
  1. Paquete de oferta
    • Oil amable: 1 kg/bottle (glass or plastic container), 25 kg/drum (stainless – metal or plastic drum with correcto sealing)
    • Polvo amable: 1 kg/aluminum foil bag, 25 kg/drum (double – layer PE bag inside cardboard drum)
  1. Fundamental Mercado
    • Mundo mercado, con importante demanda en América del Norte, Europa, Asia, ante todo utilizado en comidas y bebidas, dietéticas suplementos dietéticos, cosmetics, medicamentos recetados, and animal feed industries
  1. Utilidad Situaciones

Propiedades principales

  • Químico Construcción: Una pandilla of eight atentamente asociado grasas – soluble compounds, junto con 4 tocopherols (alpha, beta, gamma, delta) and 4 tocotrienols, with alpha – tocopherol being probably the most biologically dinámico amable. The molecular construcción includes a chromanol ring and a phytyl faceta – chain, which contribute to its antioxidant properties.
  • Llave Opciones
    • Antioxidante: One of the potente puro antioxidants. It donates a hydrogen atom to free radicals (correspondiente a hydroxyl, peroxyl radicals), parada oxidativo lesión to cell membranes, DNA, and lipoproteins. This helps blindaje células de envejeciendo, irritación, y el evento de continuo enfermedades.
    • Antiinflamatorio: Modulates the ejercicio of immune cells and reduces the fabricación de profesional – citocinas inflamatorias, sirviendo a Para aliviar irritación – asociado situaciones.
    • Poros y piel Seguridad: Promotes poros y piel bienestar por defendiendo hacia Inducido por rayos UV lesión, decreciente las miradas of wrinkles, and accelerating wound terapéutico. Él además ayuda preservar el poros y piel‘s moisture barrier.
    • Cardiovascular Ayuda: Reduces the oxidation of low – density lipoprotein (LDL) colesterol LDL, which is a key asunto dentro de la mejora of atherosclerosis, thus contributing to corazón coronario bienestar.
    • Neuroprotector: Podría asistir blindaje neurons from oxidative stress and irritación, mostrando potencial en parada neurodegenerativa enfermedades like Alzheimer’s and Parkinson’s.

Utilidad Situaciones

1. Comidas y bebidas Negocio

  • Antioxidante y conservante
    • Added to edible oils, margarines, and gordo (0.01 – 0.1% enfocar) Para detener oxidation and rancidity, extending the shelf – vida útil de mercancías. Por ejemplo, in olive oil, vitamin E helps preservar es alta calidad y gusto over time.
    • Utilizado en processed meats, dairy mercancías, and bakery objetos Para proteger hacia lipid oxidation and mejorar estabilidad del producto.
  • Dietético Fortification
    • Fortifies breakfast cereals, fuerza bars, and práctico bebidas para reforzar their vitamin E contenido material, asamblea comprador demand for nutritious comidas mercancías.

2. Dietético suplementos dietéticos

  • Standalone suplementos dietéticos
    • Allá afuera in capsule, softgel, or píldora amable (starting from 100 – 1000 IU per serving), generalmente taken to complementar el día a día consumo of vitamin E, particularmente para la gente with dietary deficiencies or particular bienestar quiere.
  • Multivitamin Formulations
    • A key ingredient in multivitamin – mineral suplementos dietéticos, ofrenda antioxidante asistir and contributing to general bienestar y eficazmente - ser.

3. Cosméticos y Privado Cuidado

  • Poros y piel – Cuidado Mercancías
    • Added to moisturizers, serums, sunscreens, and anti – envejeciendo lociones (0.5 – 5% enfocar) Para proteger el poros y piel del medio ambiente lesión, reducir la escala oxidative stress, and promote poros y piel rejuvenation. It helps mejorar poros y piel textura, reducir la escala las miradas de ventajoso rastros, y mejorar poros y piel hydration.
  • Cuidado del cabello
    • Included in shampoos, conditioners, and hair oils to nourish the scalp, detener hair lesión provocado por free radicals, and mejorar hair energía and shine.

4. Farmacéutico Negocio

  • Medicinal Formulations
    • Utilizado en actual medicamentos para tratar poros y piel situaciones correspondiente a burns, scars, and dermatitis, atribuible a its wound – terapéutico and anti – inflammatory properties.
    • Investigated for potential propósitos in treating seguro cardiovascular enfermedades, neurodegenerative problemas, and as an adjuvant recurso en cáncer terapia, aunque extra médico análisis is required.

5. Alimento para animales Negocio

  • Livestock and Poultry Feed
    • Added to animal feed (50 – 200 mg/kg) Para mejorar animal bienestar, mejorar inmune funcionar, and stop oxidative stress in animals. It además ayuda mejorar el estándar of animal – derived mercancías, correspondiente a creciente the shelf – vida útil de meat and eggs.
  • Mascota Vitamina
    • Included in pet comidas y suplementos dietéticos a asistir el general bienestar of pets, particularmente para poros y piel and coat bienestar, y para darle sabor antioxidant defenses.

Detección Estrategias

  • Excesivo – Eficiencia Cromatografía líquida (HPLC)
    • Columna: C18 (250 × 4,6 mm, 5 μm), Celular Sección: Ethanol – hexane (gradient elution), Circular Precio: 1.0 mL/min, Detection Wavelength: 295 nm (for alpha – tocopherol). This metodología precisamente cuantifica completamente diferente tocopherol types en variado muestras.
  • Fuel Chromatography – Mass Spectrometry (GC – MS)
    • Espléndido for analyzing risky and semi – risky regiones of vitamin E, ofrenda detallado detalles sobre El perfil químico y la detección pista cantidades de compuestos.
  • Fourier Remodelar Espectroscopia infrarroja (FTIR)
    • Ayuda afirmar el químico construcción of tocopherols by analyzing the atributo picos de absorción de práctico equipos, asegurándose producto alta calidad y autenticidad a lo largo de fabricación.

Suministrar & Beneficios

  • Fuentes naturales: Descubierto en muchos comidas, correspondiente a nuts (almonds, hazelnuts), seeds (sunflower seeds), vegetable oils (sunflower oil, soybean oil), and leafy inexperto verduras. Natural vitamin E es usualmente extracted from these sources utilizando solvent extraction or corporal refining estrategias.
  • Artificial Fabricación: Artificial vitamin E, ante todo dentro de la tipo de dl – alpha – tocopherol, is produced a modo de chemical synthesis, siempre que a extra valor – eficiente y constante proporcionar.
  • Versátil Funciones: Es un numero de bienestar – venta Las propiedades lo hacen extremadamente precioso a lo largo de numeroso industries, from comidas y vitamina a magnificencia and healthcare, presenting bastante empresa alternativas.
  • Aceptación regulatoria: Típicamente admitido como protegido para ser utilizado en comidas, dietary suplementos dietéticos, cosmetics, and medicamentos recetados en muchos áreas. Sin embargo, normas relating to dosage, labeling, and claims rango por nación, y productores desear Para asegurarse compliance.
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The Ultimate Guide to Natural Tocopherol-Vitamin E: Science, Benefits & Premium Sourcing

1. What is Tocopherol Vitamin E?

Tocopherol, universally recognized as Vitamina E, is a potent fat-soluble antioxidant and an essential micronutrient. It primarily exists in eight chemical forms: alpha-, beta-, gamma-, and delta-tocopherols, and alpha-, beta-, gamma-, and delta-tocotrienols. Alpha-tocopherol is the form most actively retained and utilized by the human body and is often the benchmark for Vitamin E activity. Its primary biological role involves protecting cell membranes from oxidative damage caused by especies reactivas de oxígeno (ROS) y lipid peroxidation, crucial for maintaining cellular integrity.

2. Fuente, propiedades químicas e identificación

  • Fuentes naturales primarias: Abundant in plant oils (wheat germ, sunflower, safflower), nuts (almonds, hazelnuts), seeds, green leafy vegetables, and fortified cereals. Natural d-alpha-tocopherol is preferred over synthetic dl-alpha-tocopherol due to superior bioavailability.

  • Propiedades químicas:

    • Número CAS: 59-02-9 (d-alpha-Tocopherol), 10191-41-0 (Tocopherols, mixed)

    • Fórmula molecular (MF): C29H50O2 (alpha-Tocopherol)

    • Peso molecular (PM): 430.71 g/mol

    • EINECS: 200-412-2 (d-alpha-Tocopherol)

  • Key Characteristics: A viscous, pale yellow oil, insoluble in water but soluble in fats, oils, and organic solvents. Sensitive to heat, light, and oxidation.

3. Identifying the Best Tocopherol: A Comprehensive Analysis

Choosing premium tocopherol involves scrutinizing several factors:

  • Key Components & Purity: Optar por high-purity natural d-alpha-tocopherol (>98%) or carefully standardized mixed tocopherol concentrates (rich in d-alpha, d-gamma, d-delta). Synthetic dl-alpha-tocopherol is less bioactive. Rigorous Análisis por HPLC confirms composition and potency.

  • Potency & Bioavailability: Natural d-alpha-tocopherol exhibits significantly higher biological activity (measured in International Units – IU, or mg RRR-alpha-tocopherol equivalents) compared to its synthetic counterpart. Gamma-tocopherol also possesses unique antioxidant properties relevant to health.

  • Origin & Extraction: Source matters. Look for tocopherol derived from non-GMO, sustainably sourced plant oils (e.g., European sunflower, US soybean) using advanced destilación molecular o extracción de CO2 supercrítico. This ensures minimal solvent residues and optimal preservation of bioactive isomers. Trazabilidad from raw material to final product is crucial.

  • Compliance & Safety: Premium suppliers provide comprehensive Certificados de análisis (CoA) verifying identity, purity, potency, and safety (heavy metals, pesticides, microbes) against stringent standards (USP, Ph. Eur., FCC, FDA GRAS). Adherence to cGMP (Current Good Manufacturing Practices) is non-negotiable.

  • Application & Delivery: The best form depends on the end-use:

    • Oil Soluble (d-alpha-tocopherol): Ideal for softgels, cosmetics, oils.

    • Water-Dispersible (e.g., tocopheryl acetate, tocopheryl polyethylene glycol succinate – TPGS): Essential for clear beverages, tablets, enhanced bioavailability in low-fat applications.

  • Beneficios y mecanismos para la salud:

    • Potente antioxidante: Protects cell membranes from lipid peroxidation, neutralizing free radicals.

    • Apoyo inmunológico: Mejora T-cell mediated immunity.

    • Salud de la piel: Topically and orally, it protects skin from daño por rayos UV, promotes wound healing, and combats photoaging. A key cosmeceutical ingredient.

    • Salud cardiovascular: Inhibe LDL oxidation, potentially reducing atherosclerosis risk.

    • Neurological Protection: May help protect neuronal membranes; role in age-related cognitive decline under investigation.

    • Eye Health: Protects retinal cells; associated with reduced risk of age-related macular degeneration (AMD).

  • Daily Intake & Dosage (RDA):

    • Adultos: 15 mg (22.4 IU) of alpha-tocopherol daily (NIH guidelines). Tolerable Upper Intake Level (UL) is 1000 mg/día for supplemental alpha-tocopherol. Dosages for specific health conditions should be medically supervised.

  • Instrucciones de uso: Follow product-specific recommendations. Typically taken orally with fat-containing meals to enhance absorption. For topical use, incorporate into formulations at efficacious levels (e.g., 0.1-5%).

  • Población aplicable: Generally safe for adults. Consult a physician before use by pregnant/nursing women, children, individuals with bleeding disorders (e.g., on anticoagulants like warfarin), vitamin K deficiency, or prior to surgery.

  • Crucial Considerations & Potential Side Effects:

    • High doses (>300 mg/day) may increase risk of hemorrhagic stroke.

    • Potencial anticoagulant effects; monitor closely if on blood thinners.

    • Rare side effects: nausea, diarrhea, stomach cramps, fatigue, headache, blurred vision.

    • Ensure product is stored away from light, heat, and oxygen to prevent degradation.

    • Allergen Statement: Verify sourcing if specific plant oil allergies exist (e.g., soybean).

4. Premium Sourcing: Shaanxi Zhonghong Investment Technology Co., Ltd.

Tecnología de inversión Shaanxi Zhonghong Co., Ltd. stands as a leading empresa de alta tecnología A la vanguardia de compuesto bioactivo research, manufacturing, and global supply. For over 28 años, we have specialized in the advanced extracción, aislamiento y purificación de prima extractos naturales de plantas, atendiendo las exigentes necesidades de las industrias química, de materiales y industrias de ciencias de la vida.

  • Experiencia principal: Natural Tocopherol (Vitamin E), Extractos naturales de plantas, Ingredientes activos cosméticos, Ingredientes nutracéuticos, Pharmaceutical Intermediates, Natural Pigments, Natural Sweeteners.

  • Rigor científico incomparable:

    • Fortaleza de investigación: Colaboraciones estratégicas con 5 universidades de élite a través de Joint Research Laboratories.

    • Proprietary Technology: Holding Más de 20 patentes and maintaining a biblioteca de compuestos exclusiva a nivel mundial for novel applications.

  • Cutting-Edge Quality Infrastructure:

    • Análisis avanzado: Equipado con HPLC (cromatografía líquida de alta resolución), UPLC (LC de ultra rendimiento), GC-MS (Cromatografía de gases-Espectrometría de masas), y RMN (espectroscopia de resonancia magnética nuclear).

    • Pureza superior: Our tocopherol consistently exceeds industry purity standards by >20%, guaranteed by our state-of-the-art detection systems.

  • Alcance global y personalización: Our robust supply network seamlessly delivers to más de 80 países across Asia, Europe, and the Americas. We excel in providing soluciones de ingredientes a medida tailored to the unique specifications of corporaciones farmacéuticas multinacionales, innovative research institutions, and premium supplement/formulation brands.

5. Product Specification & Certificate of Analysis (CoA)

Our Natural Tocopherol (d-alpha or Mixed) meets the highest international quality and safety standards. Below is a summary of our comprehensive CoA:

Categoría de parámetro Elemento de prueba Límite de especificación Método de prueba
Residuos de pesticidas Total BHC (α,β,γ,δ) ≤ 0,2 mg/kg GC-ECD/GC-MS/MS
Total DDT (o,p’-, p,p’-DDT, DDE, DDD) ≤ 0,2 mg/kg GC-ECD/GC-MS/MS
Quintoceno (PCNB) ≤ 0,01 mg/kg GC-ECD/GC-MS/MS
Hexaclorobenceno ≤ 0,01 mg/kg GC-ECD/GC-MS/MS
Aldrín + Dieldrín ≤ 0,01 mg/kg GC-ECD/GC-MS/MS
Ethylene Oxide (ETO) ≤ 0,02 mg/kg GC-MS (Headspace)
2-Chloroethanol (2-CE) ≤ 0,02 mg/kg GC-MS (Headspace)
Metales pesados Plomo (Pb) ≤ 0,5 mg/kg ICP-MS / AAS
Arsénico (As) ≤ 0,5 mg/kg ICP-MS / HG-AAS
Cadmio (Cd) ≤ 0,1 mg/kg ICP-MS / AAS
Mercurio (Hg) ≤ 0,1 mg/kg AAS de vapor frío / ICP-MS
Microbiológico Recuento total de placa ≤ 1.000 UFC/g USP <61> / EP 2.6.12
Levadura y moho ≤ 100 UFC/g USP <61> / EP 2.6.12
Escherichia coli Ausente en 1g USP <62> / EP 2.6.13
Especies de Salmonella. Ausente en 10g USP <62> / ISO 6579
Estafilococo áureo Ausente en 1g USP <62> / EP 2.6.13
Pseudomonas aeruginosa Ausente en 1g USP <62> / EP 2.6.13

Additional specifications include Appearance, Identification (FTIR/NMR), Assay (HPLC), Specific Rotation, Loss on Drying, Residue on Ignition, Peroxide Value, and more, compliant with USP/Ph.Eur/FCC.

6. Flujo de producción avanzado

Our tocopherol manufacturing integrates cutting-edge technology for maximum purity and sustainability:

  1. Abastecimiento de materia prima y control de calidad: Premium, identity-verified, non-GMO plant oils (e.g., sunflower, soybean distillates).

  2. Initial Extraction: Solvent extraction or physical pressing to obtain crude vegetable oil fractions rich in tocopherols.

  3. Molecular Distillation: Under high vacuum and precise temperature control, this low-temperature short-path distillation separates tocopherols from sterols, free fatty acids, and glycerides with minimal thermal degradation.

  4. Ethanol Fractionation/Crystallization: Further purification to isolate specific tocopherol isomers or remove trace impurities.

  5. Supercritical CO2 Extraction (Optional): An ultra-clean, solvent-free method for high-purity isolates, particularly for sensitive applications.

  6. Esterification (if applicable): Conversion to stable esters (e.g., Tocopheryl Acetate) using acetic anhydride under controlled conditions.

  7. Purificación final y secado: Chromatography or additional distillation steps to achieve pharma-grade purity. Removal of residual solvents/moisture.

  8. Rigorous Quality Control: Comprehensive testing against specifications (HPLC assay, heavy metals, pesticides, microbes, etc.) before release.

  9. Lavado y envasado con nitrógeno: Para evitar la oxidación durante el almacenamiento y el transporte.

7. Diversos escenarios de aplicación

  • Nutracéuticos y suplementos dietéticos: Softgels, capsules, tablets (using TPGS), functional foods/beverages for antioxidant and immune support.

  • Cosmecéuticos y cuidado de la piel: Anti-aging creams, serums, sunscreens, lip balms, hair care products for UV protection, moisturization, and barrier repair.

  • Productos farmacéuticos: Active ingredient or stabilizer in topical formulations, injectables (using solubilized forms like TPGS), and oral medications.

  • Food & Beverage Industry: Natural antioxidant/preservative (E306-E309) in oils, fats, meat products, dairy, and baked goods to prevent rancidity.

  • Nutrición animal: Feed additive for livestock, poultry, and aquaculture to improve health, fertility, and product quality.

8. Control de calidad estricto

Quality is the cornerstone of our tocopherol production. Our ISO 9001 y potencialmente ISO 22000/FSSC 22000 certified QC system ensures every batch meets or exceeds global pharmacopeial standards (USP, Ph. Eur., JP, CP). This multi-tiered approach includes:

  1. Inspección de materia prima entrante: Rigorous identity, purity, and contaminant testing using FTIR, GC, and ICP-MS.

  2. Controles en proceso (IPC): Critical parameter monitoring (temp, pressure, pH, solvent levels) at every stage, with intermediate HPLC checks for tocopherol profile.

  3. Estudios de estabilidad: Accelerated and real-time studies under ICH guidelines to establish shelf life and optimal storage conditions.

  4. Final Product Release Testing: Exhaustive analysis per CoA requirements (Assay, Isomer Profile, Heavy Metals, Pesticides, Microbiological, Residual Solvents, Physicochemical specs) using calibrated, validated methods (HPLC, GC-MS, ICP-MS, Microbial Enumeration/Pathogen Testing).

  5. Documentación y trazabilidad: Lleno cGMP documentation ensures batch traceability from raw material source through production, testing, and final distribution. Registros electrónicos de lotes (EBR) enhance accuracy and compliance. Our commitment to purity >98% y contaminant levels 20% below industry norms is demonstrable and certified.

9. Embalaje seguro y logística global

  • Embalaje primario: De calidad alimentaria bidones de HDPE (25kg, 180kg) or stainless steel containers (bulk), internally lined or flushed with high-purity nitrogen to prevent oxidation. Tamper-evident seals standard.

  • Embalaje secundario: Robust corrugated cartons for smaller units. Temperature-controlled options available for sensitive shipments.

  • Etiquetado: Compliant with destination regulations, including Product Name, CAS, Batch No., MF, MW, Expiry, Storage Conditions, Safety Symbols (GHS if applicable), Barcode.

  • Almacenamiento: -5°C to 10°C (23°F to 50°F) recommended for long-term stability. Protect from light and moisture. Keep container tightly sealed under nitrogen atmosphere.

  • Logística global: Efficient shipping via air, sea, or land. Expertise in handling hazardous materials documentation (if applicable). Cold chain logistics available. Seamless customs clearance support.

10. Análisis profundo: Mecanismos de salud, innovación y fronteras de investigación

  • Mecanismo de acción: Tocopherol’s primary role is as a chain-breaking antioxidant. It donates a phenolic hydrogen to lipid peroxyl radicals (LOO•), forming a stable tocopheroxyl radical, thereby terminating the lipid peroxidation chain reaction within cell membranes. It regenerates in vivo by Vitamina C and other reductants. Gamma-tocopherol uniquely traps especies reactivas de nitrógeno (ERN).

  • Aplicaciones industriales e innovación tecnológica: Beyond basic supplementation, innovations include:

    • Nanoemulsions & Liposomes: Enhancing topical and oral bioavailability.

    • Stabilized Derivatives: TPGS for water solubility and enhanced absorption.

    • Mezclas sinérgicas: Combining with Vitamin C, Selenium, Carotenoids for amplified antioxidant networks (“ACE antioxidants“).

    • Targeted Delivery Systems: For specific tissue delivery.

  • Fronteras y desafíos de la investigación:

    • Tocotrienols: Exploring the potentially superior cardiovascular and neuroprotective benefits of these Vitamin E isomers.

    • Nutrición personalizada: Defining optimal Vitamin E forms and dosages based on genetics (e.g., TTPA gene mutations), health status, and microbiome.

    • Cancer Prevention/Therapy: Complex role; high-dose effects require further elucidation.

    • Enfermedades neurodegenerativas: Defining efficacy in Alzheimer’s, Parkinson’s.

    • Sostenibilidad: Optimizing extraction yields, reducing waste, utilizing novel feedstocks.

    • Analytical Challenges: Precise quantification of all vitamers in complex matrices.

11. Preguntas frecuentes (FAQ)

  • Q: What’s the difference between natural and synthetic Vitamin E?

    • A: Natural (d-alpha-tocopherol) is sourced from plants and has higher bioavailability (~2x) and biological activity than synthetic (dl-alpha-tocopherol). Look for “d-” or “RRR-” on labels.

  • Q: Is topical Vitamin E effective?

    • A: Yes! It penetrates the skin, providing antioxidant protection against UV damage, improving hydration, reducing inflammation, and supporting wound healing. Stability in formulations is key.

  • Q: Can I take too much Vitamin E?

    • A: Yes. High doses (>1000 mg/day supplemental alpha-tocopherol) can increase bleeding risk, especially if on blood thinners. Stick to the RDA (15 mg) unless advised otherwise by a doctor.

  • Q: Does Vitamin E interact with medications?

    • A: It can potentiate anticoagulants (warfarin, aspirin) and reduce the efficacy of some chemotherapy drugs. Always inform your doctor about supplements.

  • Q: What’s better: alpha-tocopherol or mixed tocopherols?

    • A: Alpha is essential, but gamma and delta tocopherols offer unique benefits (e.g., trapping RNS). A balanced mixed tocopherol supplement may provide broader antioxidant coverage.

  • Q: How should I store Vitamin E oil/supplements?

    • A: Cool, dark place, tightly sealed. Refrigeration can extend shelf life. Avoid heat and humidity.

12. Where to Buy Premium Natural Tocopherol

Tecnología de inversión Shaanxi Zhonghong Co., Ltd. es su socio global de confianza para high-purity, certified natural tocopherol (Vitamin E) y specialized plant extracts.

  • Visita nuestro sitio web: Explore our full product portfolio and technical resources: aiherba.com

  • Solicite una muestra gratuita: Experimente la diferencia de calidad de Zhonghong de primera mano.

  • Contact Our Sales Team:

13. Conclusión

Tocopherol (Vitamin E) remains a cornerstone essential nutrient and a powerful lipid-soluble antioxidant with proven benefits for cellular health, immunity, skin vitality, and chronic disease prevention. Choosing the highest quality tocopherol – defined by its natural source (d-alpha), exceptional purity (>98%), rigorous safety certifications (CoA), and advanced production methods – is paramount for efficacy and safety in nutraceutical, cosmetic, and pharmaceutical applications. Tecnología de inversión Shaanxi Zhonghong Co., Ltd. apalancamientos 28 años de experiencia en compuestos bioactivos, I+D respaldada por la universidad, tecnologías de purificación patentadas, y global cGMP manufacturing to deliver premium, reliable tocopherol solutions. Contact us today to elevate your formulations.

14. Referencias

  1. National Institutes of Health (NIH) – Office of Dietary Supplements: Vitamin E Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/

  2. European Food Safety Authority (EFSA) Scientific Opinions on Vitamin E health claims (e.g., protection of DNA, proteins, lipids from oxidative damage).

  3. Traber, M. G., & Atkinson, J. (2007). Vitamin E, antioxidant and nothing more. Biología y medicina de radicales libres, 43(1), 4-15.

  4. Brigelius-Flohé, R., & Traber, M. G. (1999). Vitamin E: function and metabolism. The FASEB Journal, 13(10), 1145-1155.

  5. United States Pharmacopeia (USP) Monographs: Tocopherols / Vitamin E. USP-NF.

  6. European Pharmacopoeia (Ph. Eur.) Monographs: Vitamin E (Tocopherol).

  7. Food Chemicals Codex (FCC) Monograph: Vitamin E.

  8. Keen, M. A., et al. (2014). Vitamin E in dermatology. Indian Dermatology Online Journal, 5(2), 175–184.

  9. ICH Guidelines (Q1A-Q1E) – Stability Testing of New Drug Substances and Products.

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