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Ácido 3-O-etil ascórbico

3-O-Ethyl Ascorbic Acid factory supplier bulk Wholesale Extract factory

  1. Nombre en inglés: 3-O-Ethyl Ascorbic Acid (often abbreviated as “EAA” in skincare circles—it’s a stable, oil-soluble derivative of vitamin C, way more stable than regular L-ascorbic acid!)
  1. Especificación
    • Pureza: ≥ 99% (HPLC tested—ultra-pure, no additives or vitamin C impurities; critical for skincare efficacy)
    • Solubilidad: Soluble in both water and oil (a big win! Most vitamin C derivatives only work in one—this mixes into any skincare formula)
    • Estabilidad del pH: Works well in pH 3.0–7.0 (doesn’t break down in common skincare pH ranges, unlike fragile L-ascorbic acid)
    • Metales pesados: ≤ 5 ppm (extra strict for facial skincare—safe even for sensitive skin)
    • Estabilidad: Resists oxidation (won’t turn brown in bottles or formulas—stays potent for 12+ months)
  1. Apariencia: White to off-white fine powder with a mild, neutral aroma—definitivamente no chocolate aroma! It’s almost odorless, so it won’t alter the scent of your skincare products.
  1. N.º CAS.: 86404-04-8 (this is the real CAS for 3-O-Ethyl Ascorbic Acid, not that cocoa butter one—vital for skincare labeling!)
  1. Plazo de entrega: 3-7 Working Days (we keep bulk and small-size EAA in stock, so you won’t wait long for this skincare staple)
  1. Paquete: Small sizes: 10g/100g amber glass jars (light-resistant to protect from oxidation); bulk: 1kg aluminum tins or 25kg sealed drums (airtight—locks in purity and prevents moisture)
  1. Mercado principal: Europe, North America, Asia—anywhere people love vitamin C skincare! Super popular in brightening serums, anti-aging creams, and even sunscreen (especially in K-beauty and clean beauty brands).
  1. Escenarios de aplicación

Características principales

  • Vitamin C’s Stable Cousin: Delivers all the brightening/anti-aging benefits of vitamin C but won’t break down in light or air (no more brown serums!)
  • Dual Solubility: Mixes in water-based (toners, serums) and oil-based (moisturizers, oils) products—super flexible for formulators
  • Suave con la piel: Less irritating than L-ascorbic acid (no stinging or redness—safe for sensitive, acne-prone, or rosacea-prone skin)
  • Penetración profunda: Oil-soluble nature lets it sink deeper into the skin (works where it counts, not just on the surface)
  • Clean Beauty Friendly: 100% synthetic but non-toxic, vegan, and cruelty-free—fits every “clean label” skincare line

Aplicaciones industriales

  1. Skincare & Cosmetics
    • Brightening Serums: 2-5% concentration (the most common use—fades dark spots, hyperpigmentation, and sun damage; works for all skin tones)
    • Cremas antienvejecimiento: Mixed into day/night creams (boosts collagen production—reduces fine lines and firms skin)
    • Protectores solares: Added to SPF products (fights post-sun darkening and supports skin repair—“double protection” against UV damage)
    • Toners & Essences: Diluted in hydrating toners (lightweight brightening—great for layering under serums)
    • Sheet Masks: Soaked into mask fabrics (delivers a concentrated vitamin C boost—perfect for “glow-up” days)
  1. Cuidado del cabello
    • Sueros para el cuero cabelludo: 1-2% concentration (soothes scalp inflammation and supports healthy hair growth—reduces dandruff)
    • Hair Masks: Mixed into deep-conditioning masks (adds shine to dull hair and protects against environmental damage)
  1. Cuidado corporal
    • Body Lotions: Added to daily moisturizers (brightens uneven body skin—great for knees, elbows, or post-acne marks)
    • Self-Tanners: Mixed into self-tan products (prevents orange undertones and keeps color even—natural-looking glow)
  1. Men’s Grooming
    • Aftershaves: Gentle enough for post-shave skin (calms irritation and brightens razor burn marks)
    • Facial Moisturizers: Added to men’s daily creams (lightweight, non-greasy—delivers vitamin C benefits without the fuss)
  1. Baby & Sensitive Skin Products
    • Gentle Brighteners: Small doses (0.5-1%) in baby skincare (fades diaper rash marks or eczema scars—safe for delicate skin)
    • Calming Creams: Mixed into sensitive-skin formulas (soothes redness while gently brightening)
  1. Professional Skincare (Spas/Salons)
    • Facial Treatments: Used in in-spa serums (higher concentrations—10% for targeted dark spot removal)
    • Post-Procedure Care: Added to post-facial or post-laser products (supports skin healing and reduces post-treatment pigmentation)

3-O-Ethyl Ascorbic Acid: Premium Manufacturer & Global Supplier for Stable Vitamin C Skincare | Aiherba

Source high-purity 3-O-Ethyl Ascorbic Acid from Zhonghong, a leading fabricante y proveedor a granel. Superior stable Vitamin C derivative for cosmetics. Solicitar una muestra gratuita y obtener una competitividad precio cita.


1. What is 3-O-Ethyl Ascorbic Acid?

3-O-Ethyl Ascorbic Acid is a highly stable and oil-soluble derivative of Vitamin C (L-Ascorbic Acid). It is created through a targeted etherification process at the third hydroxyl group of the ascorbic acid molecule. This modification dramatically enhances its stability against oxidation (from light, air, and heat) and improves its skin penetration compared to pure Vitamin C. For B2B clients in the cosmetic and personal care industry, a reliable 3-O-Ethyl Ascorbic Acid manufacturer is essential for sourcing a potent, effective, and formulator-friendly active ingredient for advanced skincare solutions.

3-O-Ethyl Ascorbic Acid Benefits
3-O-Ethyl Ascorbic Acid Benefits

2. Fuente, propiedades químicas e identificadores

  • Fuente del producto: Synthetically derived from L-Ascorbic Acid (Vitamin C) through a controlled chemical etherification process with ethanol.

  • Clasificación química: Vitamin C derivative (Ascorbic Acid Ether).

  • Número CAS: 86404-04-8

  • Fórmula molecular (MF): C8H12O6

  • Peso molecular (PM): 204.18 g/mol

  • EINECS: 617-561-0

3. What Defines the Best 3-O-Ethyl Ascorbic Acid? A B2B Buyer’s Guide

Para internacional cosmetic brands and exportadores, the “best” product is defined by its ultra-high purity, brilliant white color, low odor, proven stability, and the supplier’s technical data confirming its efficacy and compatibility.

  • Ingrediente clave y eficacia: Premium 3-O-Ethyl Ascorbic Acid is a high-purity synthetic compound (e.g., ≥98% or cosmetic grade). Its scientifically validated benefits include:

    • Superior Stability: Highly resistant to oxidation, remaining effective in formulations far longer than pure L-ascorbic acid, even at neutral pH. This eliminates the need for highly acidic formulas.

    • Effective Skin Brightening & Anti-Pigmentation: Inhibits the enzyme tyrosinase, effectively reducing melanin production and helping to fade dark spots, hyperpigmentation, and achieve a more even skin tone.

    • Potente protección antioxidante: Neutralizes free radicals generated by UV exposure and pollution, protecting skin cells from oxidative damage and preventing signs of photoaging.

    • Collagen Synthesis: Boosts collagen production, helping to improve skin firmness and reduce the appearance of fine lines and wrinkles.

    • (Compliant for use in cosmetic formulations globally. Not typically used in dietary supplements.)

  • Origen y calidad: Our product is synthesized in a cGMP-compliant environment from high-purity starting materials, ensuring a consistent, high-quality, and contaminant-free ingredient.

  • Uso y dosis:

    • Uso típico: Incorporated into serums, creams, lotions, essences, ampoules, and brightening treatments.

    • Dosis recomendada: Effective in formulations at concentrations typically between 0.5% and 3%. It is compatible with a wide pH range and is oil-soluble, offering formulation flexibility.

  • Público aplicable: Formulators developing anti-aging skincare, brightening and whitening products, antioxidant serums, and general rejuvenating cosmetics.

  • Notas y efectos secundarios:

    • Precauciones: Generally well-tolerated and considered non-irritating, making it suitable for sensitive skin types. It is much less acidic than pure Vitamin C.

    • Efectos secundarios: Rare. Significantly less likely to cause the stinging or irritation associated with low-pH L-ascorbic acid formulas.

4. Why Partner with Zhonghong (Aiherba) as Your 3-O-Ethyl Ascorbic Acid Manufacturer?

Shaanxi Zhonghong Investment Technology Co., Ltd. (Marketing global: Aiherba) es una empresa de alta tecnología certificada y de confianza exportador specializing in the synthesis and purification of premium, cosmetic-active ingredients for the global B2B mercado.

  • Excelencia científica: Our joint laboratories with 5 leading universities and portfolio of 20+ patents allow us to optimize the synthesis for maximum yield, purity, and a brilliant white appearance.

  • Control de calidad inigualable: Our investment in advanced equipment like HPLC and NMR ensures our purity standards exceed typical industry specifications, guaranteeing a stable and highly effective product for your formulations.

  • Red B2B global: Con 28 años de experiencia en compuestos bioactivos, suministramos personalizado ingredientes y al por mayor cantidades a marcas multinacionales de cosméticos, al por mayor distributors, and OEM manufacturers across 80+ countries.

  • Apoyo técnico: We provide comprehensive technical dossiers, stability data, and formulation guidance, making us more than just a proveedor sino un verdadero socio de innovación para su extracto de hierbas personalizado and active ingredient needs.

5. Especificaciones detalladas del producto (COA)

Every batch is accompanied by a comprehensive Certificate of Analysis (COA) to guarantee it meets the stringent standards of the cosmetic industry.

Categoría Nombre del artículo Especificación Método de prueba
Pureza e identidad Ensayo (HPLC) ≥98,0% HPLC
Identification (IR) Cumple con la norma FT-IR
Metales pesados Plomo (Pb) ≤10 mg/kg ICP-MS
Arsénico (As) ≤2 mg/kg ICP-MS
Cadmio (Cd) ≤1 mg/kg ICP-MS
Mercurio (Hg) ≤1 mg/kg ICP-MS
Microbiología Recuento total de placa ≤1000 UFC/g USP <61>
Levadura y moho ≤100 UFC/g USP <61>
E. coli Ausente USP <62>
Salmonela Ausente USP <62>
Físico Apariencia Polvo cristalino de color blanco a blanquecino Visual
Solubilidad Soluble in oils and organic solvents In-house method

6. Proceso de producción y control de calidad

Our production involves the chemical synthesis of 3-O-Ethyl Ascorbic Acid from pharmaceutical-grade L-Ascorbic Acid. The process typically involves protecting the sensitive enediol structure of ascorbic acid, followed by a controlled etherification reaction at the third hydroxyl group using ethanol. After the reaction is complete, the protecting groups are removed, and the crude product undergoes a meticulous multi-stage purification process, including crystallization and washing with specific solvents, to obtain the final pure, crystalline powder.

Nuestro Control de calidad is integrated into every step. It starts with qualifying all raw materials, especially the L-Ascorbic Acid source. In-process controls monitor the reaction progress and the selectivity of the etherification to minimize by-products. The final product is rigorously analyzed. Cromatografía líquida de alta resolución (HPLC) with UV detection is the primary method for quantifying the 3-O-Ethyl Ascorbic Acid content and assessing chemical purity, ensuring the absence of unreacted starting materials or synthesis impurities. Espectroscopia FT-IR confirms the molecular identity and the successful etherification. We also employ ICP-MS for sensitive heavy metal detection. This multi-tiered QC protocol guarantees a product that is pure, safe, stable, and effective for cosmetic formulations.

7. Escenarios de aplicación

3-O-Ethyl Ascorbic Acid is a premier ingredient specifically for the cosmetics industry:

  • Protección de la piel: The primary application. Used in a vast array of products including facial serums, anti-aging creams, whitening/ brightening lotions, eye treatments, and day creams with antioxidant protection.

  • Cuidado del cabello: Incorporated into scalp treatments and hair serums for its antioxidant benefits and potential to improve scalp health.

  • Cosmecuticals: A flagship active in products marketed for their clinically proven efficacy in treating hyperpigmentation and photoaging.

8. Beneficios para la salud, investigación e innovación

The primary advantage over pure Vitamin C is its stability and skin permeability. Its mechanism of action remains the same once it penetrates the skin and is believed to be converted into active L-ascorbic acid. It effectively inhibits tyrosinase activity and scavenges free radicals. Current fronteras de la investigación are focused on further enhancing its delivery into the skin using nanoencapsulation technologies and exploring its synergistic effects with other actives like Vitamin E, ferulic acid, and other antioxidants. The main desafío for manufacturers is achieving a very white color and minimizing any yellow tinge, which is a sign of potential degradation or impurities. At Zhonghong, our innovación lies in our patented purification process that delivers a consistently white powder, providing our B2B partners with a superior, aesthetically perfect ingredient for their premium formulations.

9. FAQ – Preguntas frecuentes

Q: How does it compare to L-Ascorbic Acid in terms of efficacy?
A: While L-Ascorbic Acid is the gold standard, its instability is a major drawback. 3-O-Ethyl Ascorbic Acid offers very comparable efficacy in terms of brightening and antioxidant benefits but with vastly superior stability, easier formulation, and better skin tolerance.

Q: Can it be used in aqueous formulations?
A: It is inherently oil-soluble. For water-based formulas, it requires the use of solubilizers or can be incorporated into oil-in-water emulsions. Its stability allows for a broader pH range than L-ascorbic acid.

P: ¿Cuál es la vida útil típica?
A: The raw material powder has a shelf life of 24 months when stored in a cool, dry place away from light and moisture. Its stability in a final formulation is significantly higher than that of products containing pure L-ascorbic acid.

P: ¿Ofrecen muestras para el desarrollo de nuestros productos y pruebas de estabilidad?
A: Por supuesto. Ofrecemos muestra gratuita de extracto de hierbas and active ingredients to qualified businesses for evaluation and compatibility testing in their labs.

P: ¿Qué embalaje utilizan para la exportación internacional?
A: We use sealed, double-layer plastic bags with desiccant inside foil-lined cardboard drums to protect the product from moisture and light during transit, ensuring it arrives in perfect condition.

10. Dónde comprar y solicitar muestras gratuitas

Como empresa líder fabricante y proveedor global of cosmetic active ingredients, we are your trusted partner for sourcing high-quality 3-O-Ethyl Ascorbic Acid.

Contáctenos hoy para discutir sus necesidades de adquisición, solicitar una muestra gratuita para su I+D y obtener un precio mayorista competitivo.

11. Conclusión

Para B2B clients in the cosmetic industry, 3-O-Ethyl Ascorbic Acid offers a stable, effective, and versatile solution for Vitamin C skincare formulations. Choosing a supplier with advanced synthesis technology, rigorous QC ensuring a white color and high purity, and global exportar capabilities is crucial for product success. Zhonghong (Aiherba) provides not just a product, but a reliable partnership, offering a premium, well-documented ingredient that will give your brand a competitive edge, backed by decades of experience.

12. Referencias

  • Journal of Cosmetic Dermatology: Studies on the efficacy and stability of 3-O-Ethyl Ascorbic Acid in topical formulations.

  • Cosmetic & Toiletries Science Applied: Technical articles on the formulation benefits of stable Vitamin C derivatives.

  • International Journal of Pharmaceutics: Research on the skin permeation and metabolism of ascorbic acid derivatives.

  • ISO and USP standards for cosmetic ingredient testing.

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