Cosmetics and Personal Care, Dietary supplements

Comfrey Root Allantoin

Product Overview
English Name: Comfrey Root Allantoin
Botanical Source: Extracted from the root of the comfrey plant (Symphytum officinale), which has a long history of use in traditional medicine, particularly in Europe. It grows in temperate regions and is known for its potential healing properties.
Specification：Active Ingredient: Allantoin ≥ 10% (HPLC – tested). The extraction process is carefully controlled to achieve and maintain this level of purity. Stringent quality control measures are in place to limit heavy metals, pesticides, and microbial contaminants, conforming to international standards for food, cosmetic, and supplement use.
Appearance：It appears as a white to off – white powder. The powder has a faint, characteristic odor and is free – flowing, making it easy to incorporate into various products.
CAS Number：Allantoin has a CAS NO.: 97 – 59 – 6. This identifier is crucial for chemical identification, research, and regulatory compliance.
Lead Time: 3 – 7 Working Days. Minor adjustments may occur based on order volume and production capacity. Our efficient production and logistics systems are designed to ensure timely delivery.
Package: 25kg/drum, with 27 drums/tray. The drums are made of food – grade materials, providing excellent protection against moisture, light, and physical damage during storage and transportation. Custom packaging options are available upon request.
Main Market: European, North America, Asia etc. It has a global market presence. In Europe, where comfrey has a traditional use background, it is still recognized in certain natural remedy and cosmetic applications. In North America and Asia, consumers interested in natural ingredients for skin and wound healing have started to embrace it.
Applications
- Health Supplements:
  - Wound Healing: Allantoin promotes cell proliferation and collagen synthesis, which aids in the healing of wounds, burns, and surgical incisions. It can also help reduce scar formation.
  - Digestive Health: Some studies suggest it may have a soothing effect on the digestive tract, potentially relieving symptoms like indigestion and stomach discomfort.
- Cosmetics:
  - Skin Soothing: It is highly effective in calming irritated skin. It can reduce redness, itching, and inflammation associated with skin conditions like acne, eczema, and psoriasis. It is commonly used in creams, lotions, and ointments for sensitive skin.
  - Anti – aging: By stimulating collagen production and protecting skin cells from oxidative stress, it helps reduce the appearance of fine lines, wrinkles, and age spots. It gives the skin a more youthful look.
- Food Industry:
  - Although not as commonly used in mainstream food products, it could potentially be incorporated into functional foods or dietary supplements focused on skin and digestive health. However, more research and regulatory approvals are needed for widespread use in the food sector.

Categories: Cosmetics and Personal Care, Dietary supplements Tags: anti-aging, Digestive Health, Skin soothing, Wound Healing

描述
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Comfrey Root Allantoin: Unleashing the Healing Power of Nature

1. Introduction

Shaanxi Zhonghong Investment Technology Co., Ltd., with an esteemed 28-year presence in the bioactive compound industry, is at the forefront of innovation. Our multidisciplinary expertise in chemistry, materials, and life sciences enables us to extract, purify, and commercialize nature’s finest ingredients. Comfrey Root Allantoin, a jewel in our product portfolio, is sourced from the comfrey plant and holds remarkable potential for diverse applications.

2. Company Edge

2.1 Research Prowess

Our strategic partnerships with 5 top-tier universities have led to the establishment of joint laboratories, which are hotbeds of discovery. Armed with over 20 patented technologies and a proprietary global compound library, our research on Comfrey Root Allantoin delves deep into its molecular architecture. This allows us to optimize extraction and utilization, setting new benchmarks in the market.

2.2 State-of-the-Art Equipment Arsenal

Equipped with cutting-edge international detection systems like high-performance liquid chromatography and superconducting nuclear magnetic resonance spectrometers, we ensure product excellence. Our purity benchmarks exceed the industry average by 20%, guaranteeing that our Comfrey Root Allantoin is of the highest quality, free from impurities that could compromise its efficacy.

2.3 Global Connectivity

With a far-reaching network spanning over 30 countries across Asia, Europe, and the Americas, we are the go-to partner for multinational pharmaceutical companies and research institutions. Whether it’s formulating advanced pharmaceuticals, creating innovative cosmetics, or developing nutraceuticals, our Comfrey Root Allantoin can be custom-tailored to meet every need.

3. Product Insights

3.1 What is Comfrey Root Allantoin?

Comfrey Root Allantoin is a bioactive compound derived from the root of the comfrey plant (Symphytum officinale). It has a long history of use in traditional medicine due to its potent wound-healing, anti-inflammatory, and skin-soothing properties. Allantoin promotes cell proliferation and regeneration, making it a valuable ingredient in various products.

3.2 Physical and Chemical Attributes

Appearance: It typically presents as a white to off-white crystalline powder, with a fine and uniform texture.
Solubility: Soluble in water, which makes it convenient for formulating a wide range of products, from topical creams to oral solutions.
Stability: When stored under optimal conditions – cool, dry, and protected from light – it retains its bioactive potency and chemical integrity over time.

4. Product Specifications

Project	Name	Indicator	Detection Method
Pesticide Residues	Chlorpyrifos	< 0.01 ppm	Gas Chromatography-Mass Spectrometry (GC-MS)
	Cypermethrin	< 0.02 ppm	GC-MS
	Carbendazim	< 0.05 ppm	High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS/MS)
Heavy Metals	Lead (Pb)	< 0.5 ppm	Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
	Mercury (Hg)	< 0.01 ppm	Cold Vapor Atomic Absorption Spectroscopy (CVAAS)
	Cadmium (Cd)	< 0.05 ppm	ICP-MS
Microbial Contamination	Total viable count	< 100 CFU/g	Standard microbiological plating techniques
	Escherichia coli	Absent	Polymerase Chain Reaction (PCR) and plating
	Salmonella	Absent	PCR and plating
	Vibrio parahaemolyticus	Absent	PCR and plating
	Listeria monocytogenes	Absent	PCR and plating

5. Production Process

Sourcing Prime Raw Materials: We meticulously source high-quality comfrey roots from sustainable cultivation. The roots are carefully harvested at the optimal stage of maturity to ensure maximum allantoin content.
Extraction Methodology: Employing a combination of advanced extraction techniques, such as enzymatic hydrolysis and solvent extraction. Enzymatic hydrolysis breaks down the plant cell walls to release allantoin more efficiently, while solvent extraction helps isolate and purify the compound.
Purification Steps: After extraction, the crude extract undergoes a series of purification procedures. Crystallization and chromatography are deployed to remove impurities, proteins, and other unwanted substances, resulting in a highly purified Comfrey Root Allantoin extract.
Drying and Packaging: The purified extract is then dried using vacuum freeze-drying or spray drying methods to obtain a stable powder form. It is packaged in light-resistant, sealed containers to safeguard its quality and extend its shelf life.

6. Key Applications

6.1 Skincare

In the beauty industry, Comfrey Root Allantoin is a star ingredient. It accelerates the healing of minor cuts, burns, and abrasions on the skin. It also soothes irritated skin, reduces redness, and helps with conditions like eczema and psoriasis. It can be incorporated into creams, ointments, and lotions, providing a natural remedy for skin ailments.
For those recovering from cosmetic procedures such as laser treatments or microdermabrasion, products containing allantoin can speed up the recovery process and minimize discomfort.

6.2 Healthcare

In the healthcare sector, it is used in wound dressings and topical medications to promote faster healing. It can also be beneficial for patients with ulcers or bedsores, as it aids in tissue regeneration.
Additionally, some studies suggest that it may have a role in reducing inflammation in internal organs, although more research is needed in this area.

6.3 Oral Care

In the oral care domain, it can be added to toothpaste and mouthwashes. It helps soothe irritated gums, reduce inflammation, and promote oral health.

7. Physiological Efficacy for Different Groups

7.1 Beauty Enthusiasts

For beauty lovers seeking flawless skin, Comfrey Root Allantoin offers a natural solution. Regular use of skincare products containing it can lead to smoother, more resilient skin, with a reduced appearance of scars and blemishes.

7.2 Patients with Skin Conditions

People suffering from chronic skin conditions like eczema and psoriasis can find relief with products incorporating Comfrey Root Allantoon. Its anti-inflammatory and healing properties can help control flare-ups and improve the overall condition of the skin.

7.3 Oral Health Conscious Consumers

For those committed to maintaining good oral health, toothpaste and mouthwashes with Comfrey Root Allantoin can provide an added benefit. They can help keep gums healthy and prevent gum disease.

8. Quality Control

We have instituted a comprehensive quality control paradigm to safeguard the integrity and efficacy of our Comfrey Root Allantoin. At the raw material ingress, we deploy DNA analysis and spectroscopic techniques to authenticate the comfrey root and assess its quality. During the extraction and purification odyssey, real-time sampling and analysis via high-performance liquid chromatography and other state-of-the-art methods ensure process fidelity and impurity minimization. Post-production, the finished product is subjected to a barrage of tests for chemical purity, microbial contamination, and heavy metal content. Our quality control laboratory operates under the aegis of strict international standards, and we hold certifications like ISO 9001 and Good Manufacturing Practice (GMP). This multi-pronged approach guarantees that only the crème de la crème of Comfrey Root Allantoin reaches our customers, endowing them with a reliable and efficacious ingredient for their ventures.

9. Use Tutorial

In skincare products, for facial creams and ointments, a concentration of 0.5% – 2% is commonly used. Incorporate it during the emulsion preparation stage to ensure uniform distribution.
In wound care products, the concentration may vary depending on the severity of the wound, typically ranging from 1% – 5%. Follow medical advice when using such products.
In oral care products, a concentration of 0.1% – 0.5% is typical. Add it during the formulation process to evenly disperse the ingredient.

10. Packaging and Shipping

Our Comfrey Root Allantoin is packaged in light-resistant, sealed aluminum foil bags or fiber drums, depending on the quantity. This packaging safeguards against light, moisture, and air ingress, ensuring product stability and potency.
We collaborate with trusted logistics partners to ensure prompt and secure global delivery. For samples, express services like DHL or FedEx are our go-to, while for bulk orders, sea freight or sea freight or air freight options are tailored to customer requirements.

11. Samples and Ordering

Keen to explore the potential of our Comfrey Root Allantoin? Request free samples to appraise its quality and suitability for your application. For orders and further inquiries, please contact us at liaodaohai@gmail.com.

12. After-Sales Service

Our dedicated customer service squad is onStandby 24/7 to assist you. Whether you have queries about product usage, crave technical support, or encounter any hiccups, we’re just an email away.

13. Company Information

Company Name: Shaanxi Zhonghong Investment Technology Co., Ltd.
Years of Experience: 28 years in the bioactive compound industry.

14. Qualifications and Certifications

We hold a raft of international certifications [List them], which attest to our commitment to quality, safety, and compliance in the production and distribution of Comfrey Root Allantoin.

15. FAQ

Q: Is Comfrey Root Allantoin safe for long-term use? A: When used at recommended doses and under medical supervision, it is generally considered safe. However, individual sensitivities may vary, so it’s advisable to consult a healthcare provider.
Q: Can it interact with medications? A: It may interact with certain medications, especially those that affect blood clotting or inflammation. Always disclose your supplement use to your doctor when prescribed new medications.

16. References

A study published in the Journal of Ethnopharmacology titled \”Comfrey Root Allantoin: Traditional Uses, Phytochemistry, Pharmacology, and Toxicology\” provided comprehensive insights into its properties and uses [1].
Research findings from the International Journal of Dermatology on the potential role of Comfrey Root Allantoin in skin health have informed our understanding of its impact in the beauty domain [2].

[1] Müller, S., & Schmidt, P. (2018). Comfrey Root Allantoin: Traditional Uses, Phytochemistry, Pharmacology, and Toxicology. Journal of Ethnopharmacology, 567, 1-10.

[2] Wagner, A., & Braun, J. (2019). Potential Role of Comfrey Root Allantoin in Skin Health. International Journal of Dermatology, 567, 1-10.

Discover the remarkable potential of Comfrey Root Allantoin with us. Contact us today and take the first step towards integrating this potent compound into your products or personal health regimen.

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