L-Methionine
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L-Methionine

L-Methionine factory supplier

  1. English Name: L-Methionine (pronounced “el-meh-THY-oh-neen”—it’s one of the 9 essential amino acids; your body needs it but can’t make it, so you have to get it from food or supplements!)
  1. Specification
    • Purity: ≥ 99% (HPLC tested—pharmaceutical/food grade, no additives; the “L-” form is the one your body actually uses)
    • Solubility: Highly water-soluble (mixes easily into drinks, shakes, or supplement powders—no clumps)
    • Moisture: ≤ 0.5% (keeps it dry, so it doesn’t clump or lose potency)
    • Heavy Metals: ≤ 5 ppm (super safe for oral use—meets global amino acid and supplement standards)
    • Stability: 2+ years at room temp (no fridge needed—just keep it in a sealed container away from light)
  1. Appearance: White to off-white fine crystalline powder with a mild, slightly nutty, neutral aroma—not a yellowish-white solid with chocolate scent! It’s nearly odorless, so it won’t ruin the taste of your drinks or foods.
  1. CAS NO.: 63-68-3
  1. Lead time: 3–7 Working Days (we stock both small packets and bulk powder—fast for supplement brands and DIY wellness folks)
  1. Package:
    • Small sizes: 100g/500g resealable foil bags (moisture-proof for home use) or 30-count capsules (easy to take on the go)
    • Bulk: 25kg food-grade drums (lined with plastic—27 drums per tray; includes desiccants to keep it dry)
  1. Main Market: Global—North America (supplement brands), Europe (sports nutrition), Asia (functional foods and infant formula). Big with gym-goers, vegans (since it’s mostly in animal products), and people focused on liver health.
  1. Applications & Main Benefits
    • Dietary Supplements
      • Amino Acid Stacks: 500–1000mg per serving (paired with other amino acids like lysine—boosts muscle repair for gym-goers)
      • Vegan/Vegetarian Supplements: Fills the gap (since L-Methionine is scarce in plant foods—keeps veg diets balanced)
      • Liver Support Capsules: Mixed with milk thistle (helps the liver break down toxins—great for people with occasional alcohol intake)
    • Functional Foods & Beverages
      • Protein Shakes: Added to plant-based (soy, pea) proteins (boosts amino acid completeness—makes shakes more nourishing)
      • Fortified Cereals: Sprinkled on breakfast cereals (adds an essential amino acid—easy morning nutrition)
      • Infant Formula: Included in baby formula (critical for growth and brain development—mimics breast milk’s amino acid profile)
    • Sports Nutrition
      • Pre-Workout Powders: Small doses (250–500mg) mixed in (supports energy production—helps you push harder during workouts)
      • Post-Workout Recovery Drinks: Paired with whey protein (speeds up muscle repair—cuts down on soreness)
    • Pet Wellness
      • Dog/Cat Supplements: Tiny doses (50–100mg) in pet vitamins (supports liver health in senior pets—eases age-related detox issues)
      • Pet Food: Fortified into premium kibble (ensures pets get all essential amino acids—keeps coats shiny and muscles strong)

Key Benefits (Why It’s Essential!)

  • Muscle Health: Helps build and repair muscle tissue—critical for gym-goers, older adults (fights muscle loss), and anyone active
  • Liver Detox: Supports the liver’s ability to break down toxins (converts harmful substances into ones your body can flush out)
  • Amino Acid Balance: Vegans/vegetarians often lack it—supplements keep their amino acid intake complete (no nutrient gaps)
  • Brain & Nerve Function: Helps make neurotransmitters (brain chemicals) and myelin (the protective layer around nerves)—keeps your brain sharp and nerves healthy
  • Skin & Hair: Aids in making collagen and keratin (proteins that keep skin elastic and hair strong—fights dryness and breakage)

Quick Tip

Take L-Methionine with food (especially carbs!)—it helps your body absorb it better. Vegans can pair it with legumes (like beans or lentils) to make their meals’ amino acids more complete. And since it’s water-soluble, your body flushes out what it doesn’t need—no need to worry about “overdosing” on standard doses!
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L-Methionine: Pharmaceutical-Grade Essential Amino Acid for Nutraceutical & Pharmaceutical Applications – Manufacturer & Exporter Guide

1. What is L-Methionine?
For manufacturers seeking premium-grade essential amino acids, L-Methionine represents a critical sulfur-containing compound that plays vital roles in human health and nutrition. As one of the nine essential amino acids that cannot be synthesized by the human body, L-Methionine serves as a fundamental building block for protein synthesis and numerous metabolic processes. Our pharmaceutical-grade L-Methionine offers exceptional purity and bioavailability, making it an indispensable ingredient for nutraceutical formulations, pharmaceutical products, animal nutrition, and functional foods where quality and reliability are paramount.

2. Source, Chemistry & Specifications

  • Production Method: Fermentation-based production using non-GMO microorganisms

  • Chemical Identity: (S)-2-Amino-4-(methylthio)butanoic acid

  • Chemical Profile:

    • CAS No.: 63-68-3

    • MF: C₅H₁₁NO₂S

    • MW: 149.21 g/mol

    • EINECS: 200-562-9

  • Appearance: White crystalline powder or crystals

  • Solubility: Soluble in water; slightly soluble in alcohol

  • Purity Grades: 98.5-101.5% USP/EP/JP pharmacopeial standards

3. The Pharmaceutical Standard: Why Our L-Methionine Excels
For B2B clients requiring guaranteed quality, our L-Methionine delivers superior performance:

  • Key Advantages:

    • High Bioavailability: Optimal absorption and utilization

    • Fermentation-Derived: Non-GMO, natural isomer production

    • Regulatory Compliance: Meets global pharmacopeial standards

  • Essential Functions:

    • Protein Synthesis: Fundamental building block for proteins

    • Methyl Group Donor: Critical for methylation processes

    • Antioxidant Support: Precursor for glutathione synthesis

    • Detoxification Support: Supports liver function and detox pathways

  • Recommended Dosage: 500-1500 mg daily in supplements; varies by application

  • Certifications Available: USP, EP, JP, cGMP, ISO 9001, Kosher, Halal, Non-GMO

  • Target Applications: Nutritional supplements, pharmaceutical formulations, animal nutrition, functional foods

  • Safety Profile: Generally Recognized as Safe (GRAS); well-established safety profile

4. Zhonghong Biotech: Your Amino Acid Specialist
Sourcing pharmaceutical-grade L-Methionine requires advanced fermentation expertise.Shaanxi Zhonghong Investment Technology Co., Ltd. combines 28 years of biochemical manufacturing experience with state-of-the-art fermentation technology to deliver premium amino acids to global markets.

  • Technical Capabilities:

    • Advanced Fermentation: Precision-controlled fermentation processes

    • Purification Expertise: Multi-stage crystallization and purification

    • Quality Assurance: Comprehensive testing exceeding pharmacopeial requirements

  • Global Compliance: Full documentation meeting international regulatory standards

5. Scientific Excellence: Biological Significance
L-Methionine’s essential roles stem from its unique biochemical properties:

  • Serves as rate-limiting substrate for protein synthesis

  • Provides methyl groups for numerous metabolic reactions

  • Acts as precursor for glutathione, cysteine, and taurine

  • Supports cellular antioxidant defense systems

6. Pharmaceutical-Grade Quality Assurance
Our rigorous quality control ensures every batch meets the highest standards:

Certificate of Analysis (COA) Summary – L-Methionine (USP Grade)

Category Parameter Specification Test Method
Identity Optical Rotation +21.0° to +25.0° USP <781>
Assay L-Methionine Content 98.5-101.5% USP <341>
Purity Related Substances ≤ 0.5% HPLC
Safety Heavy Metals ≤ 10 ppm USP <231>
Chloride ≤ 0.05% USP <221>
Microbiology Total Plate Count ≤ 1000 CFU/g USP <61>
Yeast/Mold ≤ 100 CFU/g USP <61>

7. Advanced Manufacturing Process
Our pharmaceutical-grade production ensures superior quality:

  1. Fermentation: Controlled fermentation using non-GMO microorganisms

  2. Separation: Precision separation and purification

  3. Crystallization: Controlled crystallization for optimal purity

  4. Drying: Precision drying to optimal moisture content

  5. Milling: Controlled particle size distribution

  6. Quality Control: Comprehensive analytical testing

8. Professional Applications & Usage

  • Nutraceuticals: Amino acid supplements, sports nutrition, wellness products

  • Pharmaceuticals: Parenteral nutrition, prescription supplements

  • Animal Nutrition: Feed additives, pet nutrition

  • Functional Foods: Fortified foods, nutritional beverages

Usage Guidelines:

  • Human Nutrition: 500-1500 mg per serving

  • Animal Feed: 0.5-2% of feed composition

  • Pharmaceuticals: According to formulation requirements

  • Food Fortification: 0.1-0.5% of final product

9. Global Supply Chain Excellence

  • Packaging: 25kg fiber drums with double polyethylene liners

  • Storage: Cool, dry conditions in original packaging

  • Shelf Life: 36 months when stored properly

  • Logistics: Global shipping with full documentation support

10. Partnership Opportunities
We offer:

  • Custom particle sizes for specific applications

  • Private labeling and custom packaging

  • Technical support for formulation development

  • Regulatory documentation for global markets

Contact Our Technical Team:

11. Technical FAQ

  • Q: What’s the difference between DL-Methionine and L-Methionine?
    A: L-Methionine is the natural, biologically active form; DL-Methionine is a racemic mixture

  • Q: Can you provide different particle sizes?
    A: Yes, we offer various particle sizes for different application needs

  • Q: What documentation do you provide?
    A: Comprehensive COA, MSDS, and regulatory support documents

  • Q: Do you offer fermentation-based production?
    A: Yes, we use advanced fermentation technology for natural production

  • Q: What’s your minimum order quantity?
    A: MOQ is 25kg for standard products, with flexibility for larger orders

12. Final Call to Action
Ensure superior quality in your formulations with our pharmaceutical-grade L-Methionine. Contact us today to discuss your specific requirements and request samples for your product development.

Contact us now for technical specifications and samples:

References:

  1. USP43-NF38. (2020). Methionine Monograph. United States Pharmacopeia

  2. EFSA Panel on Dietetic Products. (2015). Scientific Opinion on Amino Acids

  3. Journal of Nutrition. (2022). Methionine in Human Health and Disease

  4. FDA. (2023). Generally Recognized as Safe (GRAS) substances

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