Eleuthero Extract: Nature’s Premier Adaptogen | Sourced & Perfected by Zhonghong Tech

1. What is Eleuthero?

Eleuthero (Eleutherococcus senticosus), commonly known as Siberian Ginseng or Ci Wu Jia (刺五加), is a revered adaptogenic shrub native to Northeast Asia. For centuries in Traditional Chinese Medicine (TCM) and Russian herbalism, its root and rhizomes have been prized for enhancing vitality, boosting resilience to stress, and supporting overall well-being. Unlike true ginseng (Panax spp.), Eleuthero belongs to the Araliaceae family but shares similar tonic properties, promoting homeostasis within the body.

2. Product Source, Chemical Properties & Identification

• Botanical Source: Dried roots and rhizomes of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim.

• Key Bioactive Constituents: Eleutherosides (B, E primary markers), Eleutherol, Isofraxidin, Polysaccharides, Lignans, Phenolic compounds.

• CAS Number: 97676-24-1 (for Eleuthero extract)

• Molecular Formula (MF): Complex mixture – Eleutheroside B (C₃₄H₄₆O₁₈) is a key marker.

• Molecular Weight (MW): Varies per compound – Eleutheroside B: 742.73 g/mol.

• EINECS: Not typically assigned for complex botanical extracts; individual compounds may have listings.

3. Premium Eleuthero Extract: The Zhonghong Standard

Zhonghong Tech defines “best” through unparalleled quality, purity, and traceability:

• Core Ingredients: Standardized Eleuthero Root & Rhizome Extract. Key markers: Eleutherosides B & E (typically 0.8% min), Total Eleutherosides.

• Health Benefits (Evidence-Based & Compliant):

  • Adaptogenic Powerhouse: Clinically shown to enhance resistance to physical, chemical, and biological stressors, modulating the HPA axis.

  • Cognitive & CNS Support: Improves mental focus, reduces fatigue, supports nerve function (supports neurotransmitter balance).

  • Immune Modulation: Enhances non-specific immune defense mechanisms (macrophage activation, NK cell activity).

  • Physical Performance & Recovery: Increases endurance, reduces oxidative stress post-exercise.

  • Overall Vitality: Supports adrenal function and promotes a balanced stress response.

• Recommended Daily Intake: Typical dosage ranges from 300mg to 1200mg daily of standardized extract (often providing 0.8-1.0% Eleutherosides), typically divided. Consult a healthcare provider for personalized advice.

• Origin: Sourced from pristine regions in China & Russia, ensuring optimal phytochemical profiles. Fully traceable supply chain.

• Usage: Easily incorporated into capsules, tablets, powders, functional beverages, and liquid tonics.

• Target Audience: Adults seeking stress resilience, enhanced energy, cognitive support, immune boost, and athletes.

• Critical Considerations:

  • Drug Interactions: Potential interaction with anticoagulants (warfarin), immunosuppressants, sedatives, digoxin, CYP3A4/P-gp substrates. Crucial to consult a physician.

  • Medical Conditions: Contraindicated in uncontrolled hypertension, during acute infections, or for individuals with hormone-sensitive conditions. Avoid during pregnancy & lactation.

  • Side Effects: Generally well-tolerated at recommended doses. Rare cases may include mild insomnia, drowsiness, headache, or gastrointestinal upset.

  • Quality is Paramount: Only use extracts from reputable suppliers like Zhonghong with full COA disclosure to avoid adulteration or contaminants.

4. Introducing Shaanxi Zhonghong Investment Technology Co., Ltd.

Zhonghong Tech stands as a premier high-tech enterprise vertically integrated across R&D, collaborative innovation, advanced manufacturing, and global distribution, specializing in chemistry, materials, and life sciences. Our core expertise lies in the extraction, isolation, purification, and commercial application of bioactive plant constituents.

• Portfolio: Premium Natural Plant Extracts, Cosmetic Actives, Nutraceutical & Pharmaceutical Ingredients, Natural Pigments, Dietary Supplements, Food & Beverage Additives, Natural Sweeteners.

• Scientific Prowess: Proprietary 20+ patented technologies and a globally exclusive compound library forged through strategic joint laboratories with 5 elite universities.

• Cutting-Edge QC: HPLC (High-Performance Liquid Chromatography), NMR (Nuclear Magnetic Resonance Spectroscopy), GC-MS ensure purity standards exceeding industry norms by 20%+.

• Global Reach: Serving 80+ countries across Asia, Europe, and the Americas, providing bespoke ingredient solutions to multinational pharmaceutical corporations and research institutions.

• Legacy: 28 years of dedicated expertise in bioactive compound discovery and production.

5. Product Specification & Certificate of Analysis (COA)

Zhonghong’s Eleuthero Extract meets stringent international quality and safety standards:

Additional Specifications: Appearance (Fine Brown Powder), Loss on Drying (≤ 5.0%), Ash Content (≤ 5.0%), Solubility, Assay (Eleutherosides B+E by HPLC – e.g., ≥ 0.8%).

6. Advanced Production Flow

Zhonghong’s process ensures maximum bioactive preservation:

1. Sourcing & Authentication: Strict botanical ID (Macroscopic/Microscopic, DNA barcoding, TLC).

2. Pre-processing: Controlled washing, drying, milling.

3. Extraction: Optimized solvent extraction (e.g., Ethanol/Water) under controlled T, P, time.

4. Concentration: Vacuum evaporation.

5. Purification: Advanced macroporous resin chromatography, membrane filtration (UF/NF).

6. Standardization: Precise blending to achieve specified Eleutheroside content (HPLC-controlled).

7. Drying: Spray drying or vacuum drying.

8. QC Release: Full HPLC, GC-MS, ICP-MS, Microbiological testing against spec.

7. Application Scenarios

• Dietary Supplements: Capsules, tablets, softgels for stress support, energy, immunity.

• Functional Foods & Beverages: Energy bars, shots, teas, tonics.

• Sports Nutrition: Pre-workout, post-recovery formulations.

• Cosmeceuticals: Anti-fatigue, revitalizing skincare serums/creams.

• Veterinary Health: Pet stress & immune support products.

8. Rigorous Quality Control (QC)

Zhonghong Tech’s ISO 9001 & GMP-compliant QC system guarantees consistency, safety, and efficacy:

• Identity: HPTLC (High-Performance Thin-Layer Chromatography), Botanical Microscopy, DNA Authentication.

• Purity & Assay: HPLC-DAD/ELSD for Eleutherosides quantification; GC-MS for solvent residues; ICP-MS for heavy metals; validated Microbiological Testing (USP/EP).

• Stability: Real-time & accelerated ICH stability studies determining shelf life under various conditions (temp, humidity).

• Process Validation: All critical process parameters (CPPs) monitored and controlled. Full traceability from raw herb to finished product via ERP system.

• Documentation: Comprehensive COA, GMP certificates, Spec Sheets, Stability Data provided.

9. Packaging & Global Logistics

• Primary: Double food-grade polyethylene (PE) bags with aluminum foil lining.

• Secondary: Sealed fiber drums (HDPE) or cardboard cartons.

• Storage: Cool (<25°C), dry place, protected from light.

• Shelf Life: Typically 24 months unopened.

• Logistics: Efficient global shipping via air/sea freight; compliant with international regulations (including documentation for customs).

10. Health Benefits & Mechanisms / Research & Innovation

• Mechanistic Insights: Eleutherosides modulate stress response via the HPA axis, influencing cortisol regulation. They enhance mitochondrial function (ATP production), exhibit antioxidant activity (scavenging ROS), stimulate immune cells (macrophages, NK cells, T-lymphocytes), and may influence neurotransmitter levels (acetylcholine, serotonin).

• Clinical Relevance: Supported by studies demonstrating reduced fatigue, improved cognitive function under stress, enhanced exercise tolerance, and lowered incidence of respiratory infections.

• Zhonghong’s Innovation: Focus on novel extraction techniques (e.g., pressurized liquid extraction – PLE, enzymatic-assisted extraction) for higher yields and purity. Development of unique eleutheroside-enriched fractions via preparative HPLC. Research into synergistic adaptogen blends.

• Frontiers & Challenges: Deeper understanding of receptor-level interactions, personalized adaptogen therapy, sustainable wild-crafting/cultivation, and standardization of complex extracts for consistent clinical outcomes.

11. Frequently Asked Questions (FAQ)

• Q: Is Eleuthero the same as Ginseng? A: No. While both are adaptogens, Eleuthero (Eleutherococcus senticosus) is botanically distinct from true Ginseng (Panax ginseng, P. quinquefolius). They share some functional benefits but have different primary active compounds.

• Q: How long does it take to feel the effects of Eleuthero? A: Adaptogens often work subtly over time. Consistent use for 2-6 weeks is typically needed to experience significant benefits like reduced fatigue and improved stress resilience. Acute effects on focus might be noticed sooner.

• Q: Can I take Eleuthero with my prescription medications? A: Crucially, consult your doctor or pharmacist. Eleuthero may interact with blood thinners (warfarin), immunosuppressants, diabetes drugs, sedatives, and others. Professional guidance is essential.

• Q: What makes Zhonghong’s Eleuthero Extract superior? A: Our extract boasts >20% higher purity verified by HPLC & NMR, utilizes patented extraction tech, is standardized to key markers (Eleutherosides B+E), undergoes rigorous multi-stage QC, and is backed by 28 years of bioactive compound expertise and university research collaborations.

• Q: Is your Eleuthero Extract non-GMO, gluten-free, and allergen-safe? A: Yes. Our standard Eleuthero extract is Non-GMO, Gluten-Free, and free from major allergens (Dairy, Soy, Egg, Wheat, Peanuts, Tree Nuts, Fish, Shellfish). Specific COA confirms.

• Q: What is your Minimum Order Quantity (MOQ)? A: Contact us directly to discuss MOQ based on your specific needs and product format (bulk powder, customized extract, etc.).

12. Procure Premium Eleuthero Extract

Source the finest Eleuthero Root Extract directly from the manufacturer! Shaanxi Zhonghong Investment Technology Co., Ltd. offers competitive pricing, unmatched quality, and reliable global supply.

• Request a Quote: Contact our sales team.

• Get Free Samples: Experience the Zhonghong quality difference firsthand.

• Visit Us Online: Explore our full product portfolio.

Contact: Mr. Liaoda Hai
Email: liaodaohai@gmail.com
Website: https://www.aiherba.com

13. Conclusion

Eleuthero extract stands as a scientifically validated, potent adaptogen crucial for modern health challenges. Choosing a supplier like Shaanxi Zhonghong Investment Technology Co., Ltd. – with its vertically integrated process, university-backed R&D, cutting-edge purification tech (HPLC/NMR), stringent QC exceeding industry standards, and global regulatory compliance – guarantees an ingredient of the highest purity, efficacy, and safety for your nutraceutical, functional food, or cosmeceutical applications. Elevate your formulations with Zhonghong’s premium Eleuthero Extract.

14. References

• Panossian, A., & Wikman, G. (2010). Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity. Pharmaceuticals, *3*(1), 188–224.

• Davydov, M., & Krikorian, A. D. (2000). Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. Journal of Ethnopharmacology, *72*(3), 345–393.

• European Medicines Agency (EMA). (2014). Assessment report on Eleutherococcus senticosus (Rupr. et Maxim.) Maxim., radix. EMA/HMPC/680621/2013.

• USP-NF Monographs (Potential references for testing methods).

• ICH Guidelines (Q1A(R2), Q2(R1) – Stability & Validation).

• Zhonghong Tech Internal Research & Quality Documents.