Caffeine

Caffeine

  1. English Name: Caffeine (it’s the world’s most popular natural stimulant—you’ll find it in coffee, tea, chocolate, and even some plants like guarana! No fancy nicknames needed; everyone just calls it “caffeine”)
  1. Specification
    • Purity: ≥ 99.5% (HPLC tested—pharmaceutical/food grade, no weird additives or residues)
    • Solubility: Easily soluble in water (mixes like a dream—perfect for energy drinks, supplements, or even skincare)
    • Moisture: ≤ 0.5% (keeps it dry, no clumping—stays powdery and easy to work with)
    • Heavy Metals: ≤ 5 ppm (super safe for oral/topical use—meets every global safety standard out there)
    • Melting Point: ~238°C (stable at room temp—won’t break down in storage or during light processing)
  1. Appearance: White, needle-like crystalline powder with a mild, neutral aroma—definitely not a yellowish-white solid with chocolate scent! It’s basically odorless, so it won’t mess up the taste or smell of whatever you mix it into.
  1. CAS NO.: 58-08-2 (this is the real CAS for caffeine—forget that cocoa butter one; they’re totally different! Important for labeling and compliance)
  1. Lead time: 3–7 Working Days (we keep this stuff in stock year-round—no long waits for your energy-boosting needs)
  1. Package:
    • Small sizes: 100g/1kg resealable foil bags (light-proof to keep it fresh—great for small-batch products or home use)
    • Bulk: 25kg food-grade drums (lined with plastic to block moisture—27 drums fit on one tray, so shipping is easy)
  1. Main Market: Global—Europe, North America, Asia—anywhere people need a pick-me-up! It’s huge in beverages, supplements, skincare, and even some snacks.
  1. Application Scenarios

Key Features

  • Go-To Stimulant: Gives that classic energy boost and sharpens focus—no wonder it’s in so many daily products (think morning coffee or pre-workout drinks)
  • Super Versatile: Works in drinks, pills, creams—even pet products! You can mix it into almost anything without issues.
  • Controllable Effects: Doses are easy to adjust (from 50mg for a gentle lift to 200mg for a stronger boost)—no guesswork.
  • Natural or Synthetic: Sourced from coffee/tea beans (natural) or made in labs (synthetic)—both work the same, so you pick what fits your brand.
  • Budget-Friendly: One of the most affordable, effective stimulants—great for both premium and everyday products.

Industry Applications

  1. Beverages (the biggest use!)
    • Energy Drinks/Seltzers: 80–150mg per can (the main ingredient that gives you that “kick”—paired with B-vitamins for extra energy)
    • Coffee/Tea Products: Added to instant coffee, iced tea, or cold brews (boosts caffeine levels for people who want more of a jolt)
    • Sports Drinks: Small doses (50–75mg) in post-workout drinks (fights fatigue without overstimulating)
  1. Dietary Supplements
    • Pre-Workout Powders: 150–200mg per serving (boosts energy and performance at the gym—paired with creatine or beta-alanine)
    • Weight Loss Blends: 100mg per capsule (helps speed up metabolism—works with green tea extract for better results)
    • Focus Pills: 75–100mg per dose (sharpens concentration for work or studying—mixed with L-theanine to avoid jitters)
  1. Cosmetics & Skincare
    • Eye Creams: 0.5–1% concentration (reduces dark circles and puffiness—constricts blood vessels gently)
    • Cellulite Creams: 1–2% in body lotions (temporarily tightens skin and reduces the look of cellulite—popular in anti-aging lines)
    • Hair Growth Serums: Small amounts in scalp treatments (stimulates hair follicles—may help with mild hair loss)
  1. Food & Snacks
    • Energy Bars: 50–75mg per bar (quick energy for on-the-go—paired with nuts or dried fruit)
    • Gum/Candy: 30–50mg per piece (subtle energy boost without drinking anything—great for long drives or meetings)
  1. Pet Wellness (super specialized!)
    • Senior Pet Energy Supplements: Tiny doses (10–20mg) in dog powders (gentle lift for less active older dogs—safe in small amounts)

Pro Tip

For supplements or drinks: Pair caffeine with L-theanine (a amino acid from green tea)—it takes away the jitters while keeping the focus and energy. For skincare: Always do a patch test first—some sensitive skin might get a little red, but it’s usually mild!

Global Source for Premium Bulk Caffeine: Manufacturer & Supplier for Pharma, Nutra, and Food | Free Samples

Are you sourcing high-purity Caffeine for your dietary supplements, energy drinks, or pharmaceutical formulations? Look no further. Shaanxi Zhonghong Investment Technology Co., Ltd. is a leading international manufacturer and exporter of premium botanical ingredients. We specialize in producing bulk Caffeine of exceptional purity (>98.5%) for B2B clients worldwide. Request your free Caffeine sample today to verify our quality.

1. What is Caffeine?

Caffeine is a naturally occurring central nervous system stimulant, belonging to a class of compounds called xanthine alkaloids. It is one of the most widely consumed bioactive ingredients in the world, renowned for its ability to ward off drowsiness and restore alertness. For manufacturers, it is a critical functional component in everything from energy shots to weight management supplements.

2. Source, Chemistry & Key Specifications

  • Product Source: Primarily extracted from the seeds of Coffea arabica (coffee beans), leaves of Camellia sinensis (tea), and seeds of Paullinia cupana (guarana). We source the finest raw materials for optimal yield and purity.

  • Key Active: Caffeine (1,3,7-Trimethylxanthine)

  • CAS Number: 58-08-2

  • Molecular Formula: C₈H₁₀N₄O₂

  • Molecular Weight: 194.19 g/mol

  • EINECS: 200-362-1

  • Appearance: White, crystalline powder or odorless needles.

  • Solubility: Sparingly soluble in water; freely soluble in hot water and organic solvents like chloroform.

3. Why is Zhonghong’s Caffeine Your Best Choice?

Selecting the right caffeine supplier is critical for your product’s efficacy and safety. Here’s how we deliver unmatched value:

  • Superior Purity & Composition: Our advanced purification processes result in Caffeine with a typical purity of >98.5%, verified by HPLC (High-Performance Liquid Chromatography). This exceeds standard industry specifications, ensuring a potent and consistent raw material for your production lines.

  • Global Compliance & Certification: Our Caffeine is produced in facilities that adhere to stringent international standards, including cGMP, ISO, and USP/EP pharmacopeia guidelines. It is suitable for food, pharmaceutical, and nutraceutical applications. Every batch is backed by a comprehensive Certificate of Analysis (COA).

  • Origin & Traceability: We import premium raw materials and maintain full traceability from source to final product. Our vertically integrated process guarantees you receive a batch-to-batch consistent ingredient.

  • Versatile Applications:

    • Dietary Supplements & Nutraceuticals: Key ingredient in fat-burning pills, pre-workout blends, and energy capsules for its metabolic and ergogenic effects.

    • Food & Beverage (F&B): Essential for energy drinks, sodas, gum, and energy bars to provide a stimulating effect.

    • Pharmaceuticals: Used in over-the-counter (OTC) alertness aids and analgesic combinations (e.g., with aspirin) to enhance efficacy.

    • Cosmetics: Incorporated into cellulite creams and under-eye serums for its vasoconstrictive and antioxidant properties.

  • Usage & Dosage Guidelines:

    • Form: Fine White Powder.

    • Recommended Dosage: Varies significantly by application. For dietary supplements, common doses range from 50mg to 200mg per serving. Always comply with regional regulatory limits (e.g., FDA, EFSA). EFSA considers a daily intake of up to 400mg safe for adults.

    • Target Audience: Product formulators in the supplement, F&B, pharmaceutical, and cosmetic industries.

  • Precautions & Side Effects:

    • Side Effects: Overconsumption can lead to insomnia, nervousness, restlessness, stomach upset, tachycardia, and muscle tremors.

    • Considerations: Not recommended for children, pregnant or breastfeeding women, or individuals sensitive to stimulants. Those with cardiovascular conditions or anxiety disorders should use caution.

    • Disclaimer: This information is for manufacturing guidance only. End-product labeling and dosage are the responsibility of the finished goods manufacturer.

4. Company Introduction: Why Partner with Zhonghong?

With 28 years of expertise, Shaanxi Zhonghong Investment Technology Co., Ltd. is a high-tech enterprise at the forefront of plant extraction technology. We serve as a strategic partner for global brands in chemical, material, and life science sectors.

  • Robust R&D Infrastructure: We maintain joint laboratories with 5 top-tier universities, drive innovation with 20+ patents, and manage a globally exclusive compound library.

  • Cutting-Edge Quality Assurance: Our investment in world-class instrumentation—including HPLC, UPLC, GC-MS, and Superconducting NMR—ensures our purity standards exceed industry averages by over 20%.

  • Global B2B Network: Our supply chain covers 80+ countries across Asia, Europe, and the Americas. We are the preferred customized herbal extract provider for multinational pharmaceutical corporations, research institutions, and major supplement brands.

  • End-to-End Expertise: From importing raw materials to manufacturing a wide spectrum of products (extracts, cosmetic actives, pharma intermediates, food additives), Zhonghong delivers excellence and reliability.

5. Health Benefits & Mechanism of Action

Caffeine’s primary benefit is its action as a central nervous system stimulant. Its mechanisms include:

  • Cognitive Enhancement & Alertness: Acts as an adenosine receptor antagonist in the brain, blocking the calming effects of adenosine, which leads to increased neuron firing and the release of other neurotransmitters like dopamine and norepinephrine.

  • Ergogenic Aid: Enhances athletic performance by increasing adrenaline levels, mobilizing fatty acids from fat tissues, and improving muscle contraction.

  • Metabolic Boost: Temporarily increases metabolic rate and promotes lipolysis, making it a staple in weight management formulations.

  • Antioxidant Properties: Exhibits antioxidant activity, helping to neutralize free radicals.

6. Product Specification & Certificate of Analysis (COA)

We guarantee full transparency. Every batch includes a detailed COA. Below is a summary of our standard testing protocol.

Table: Caffeine – Key Quality Control Parameters

Category Parameter Specification Test Method
Assay Caffeine Content (Dry Basis) ≥ 98.5% – 101.0% USP <621> (HPLC)
Physical/Chemical
Appearance White crystalline powder Visual
Odor Odorless Olfactory
Loss on Drying ≤ 0.5% USP <731>
Residue on Ignition ≤ 0.1% USP <281>
Heavy Metals Lead (Pb) ICP-MS
Heavy Metals ≤ 10 ppm
Arsenic (As) ICP-MS
≤ 3 ppm
Cadmium (Cd) ICP-MS
≤ 1 ppm
Mercury (Hg) CV-AAS
≤ 1 ppm
Pesticides Total Pesticide Residues Complies with USP/EP/JP GC-MS/MS, LC-MS/MS
(e.g., Chlorpyrifos, Cypermethrin) Specific limits per compound
Microbiology Total Aerobic Microbial Count ≤ 1000 CFU/g USP <61>
Total Combined Yeast & Mold ≤ 100 CFU/g USP <61>
E. coli Absent in 10g USP <62>
Salmonella spp. Absent in 10g USP <62>
Other Residual Solvents (Class 2 & 3) Meets ICH Q3C Guidelines GC

7. Production Process: Precision from Bean to Powder

  1. Sourcing & Inspection: Premium raw materials (e.g., green coffee beans) are selected and rigorously tested.

  2. Decaffeination & Extraction: Caffeine is removed using advanced methods like Supercritical CO2 Extraction (SFE) or water processing, ensuring high yield and environmental friendliness.

  3. Purification & Crystallization: The crude extract undergoes multiple purification and crystallization steps to remove impurities, chlorophyll, and other alkaloids.

  4. Drying & Milling: The purified caffeine crystals are dried to precise moisture levels and milled to a uniform, fine powder.

  5. QC Testing & Release: The final product is subjected to a full battery of tests (HPLC for assay, GC-MS for solvents, ICP-MS for metals, microbiology) before being approved for shipment.

8. Application Scenarios

  • Sports Nutrition: Pre-workout powders, fat burners.

  • Functional Beverages: Energy drinks, shots, and enhanced waters.

  • Pharmaceuticals: OTC alertness tablets and analgesic combinations.

  • Cognitive Supplements: Nootropic stacks and focus formulas.

  • Cosmeceuticals: Anti-cellulite and under-eye creams.

9. Uncompromising Quality Control (300 Words)

At Zhonghong, quality is embedded in our DNA. Our ISO-certified quality management system governs every step, from raw material qualification to final product release. We begin with rigorous raw material vetting, using HPTLC and HPLC for identity confirmation and screening for contaminants. In-Process Controls (IPC) are meticulously monitored throughout extraction and purification to ensure batch consistency and process validation. Our dedicated QC laboratory is equipped with state-of-the-art technology—including UPLC/HPLC for precise assay quantification, GC-MS for residual solvent and pesticide analysis, ICP-MS for ultra-sensitive heavy metal detection, and advanced microbiological testing suites. We conduct exhaustive stability studies to define shelf life and optimal storage conditions. Meticulous batch records ensure full traceability from source to your facility. This relentless commitment to data-driven quality allows us to guarantee that our purity standards consistently surpass industry norms by over 20%, providing you with a ingredient of uncompromised safety and efficacy for your premium products.

10. Packaging & Logistics

  • Packaging: Options include double-lined food-grade Kraft paper bags (25kg), fiber drums (25kg), or customized packaging to meet your needs.

  • Storage: Store in a cool, dry, well-ventilated place away from direct sunlight. Keep containers tightly sealed.

  • Shelf Life: Typically 24 months when stored under recommended conditions.

  • Logistics: We are experienced international exporters, shipping via air, sea, or land. All necessary documentation (COA, MSDS, Certificate of Origin, Commercial Invoice) is provided for smooth customs clearance.

11. Frequently Asked Questions (FAQ)

  • Q: What is your Minimum Order Quantity (MOQ)? A: We cater to both large-scale bulk buyers and smaller R&D projects. Contact us to discuss your specific MOQ needs.

  • Q: Can you provide customized specifications? A: Absolutely. As a leading customized herbal extract manufacturer, we can tailor particle size, purity grades (e.g., USP/EP), and packaging to your exact requirements.

  • Q: Do you offer free samples? A: Yes, we encourage potential B2B partners to request a free sample to test our quality, solubility, and compatibility with your formulations.

  • Q: Are you an organic-certified supplier? A: We offer both conventional and certified organic Caffeine. Please specify your requirement when inquiring.

  • Q: What is the lead time for orders? A: Lead times vary based on order size and destination. We provide transparent timelines with every quote.

12. Where to Buy & Request Free Samples

Ready to partner with a reliable caffeine manufacturer? Contact us today for a quote, technical data sheets, or to discuss your customized extract needs.

13. Conclusion

In the competitive global market for active ingredients, reliability, purity, and technical partnership are paramount. Shaanxi Zhonghong, with its nearly three decades of experience, cutting-edge production capabilities, and unwavering commitment to quality, stands as your premier B2B supplier and manufacturer of high-purity Caffeine. We provide more than just a product; we deliver tailored solutions and trusted partnership for brands in the pharmaceutical, nutraceutical, and F&B industries. Contact us today to discuss your sourcing needs.

14. References

  • United States Pharmacopeia-National Formulary (USP-NF)

  • European Pharmacopoeia (Ph. Eur.)

  • FDA Generally Recognized as Safe (GRAS) notices.

  • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2015). Scientific Opinion on the safety of caffeine.

  • Internal Zhonghong R&D and quality control documentation.

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