Apigenin
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Apigenin

Apigenin factory supplier bulk Wholesale Extract factory

  1. English Name: Apigenin (it’s a natural flavonoid—pronounced “ay-pij-uh-nin!” Sourced from common plants like chamomile flowers, parsley, and celery, but most supplements use concentrated extracts from chamomile for potency)
  1. Specification
    • Purity: ≥ 98% (HPLC tested—super pure, no plant bits or fillers; some formulations mix with 5% maltodextrin to prevent clumping)
    • Solubility: Slightly soluble in water; dissolves well in ethanol, DMSO, and vegetable oils (perfect for capsules, topical serums, or liquid supplements)
    • Moisture: ≤ 0.5% (keeps it dry, no clumping or losing its calming/antioxidant properties)
    • Heavy Metals: ≤ 5 ppm (extra strict—safe for oral and topical use, even for sensitive users)
    • Melting Point: ~345°C (super stable at room temperature—won’t break down during storage or mild processing)
  1. Appearance: White to off-white crystalline powder with a mild, subtle, floral aroma—definitely no chocolate aroma! It smells faintly like dried chamomile, soft and calming, not overpowering.
  1. CAS NO.: 520-36-5 (this is the real CAS for apigenin, not that cocoa butter one—critical for supplement labeling or skincare compliance!)
  1. Lead time: 3-7 Working Days (we keep high-purity apigenin in stock, so you won’t wait long for this versatile flavonoid)
  1. Package: Small sizes: 1g/10g/100g amber glass vials (light-resistant to protect its crystalline structure); bulk: 1kg aluminum tins or 25kg sealed drums (airtight, food-grade lined—locks in purity and prevents oxidation)
  1. Main Market: Europe, North America, Asia—anywhere people want natural calming ingredients, anti-aging skincare, or antioxidant supplements! Super popular in sleep support products, natural skincare, and stress-relief blends.
  1. Application Scenarios

Key Features

  • Calming Flavonoid Star: It binds to GABA receptors in the brain (like natural “chill pills”)—eases stress and improves sleep without grogginess
  • Antioxidant Powerhouse: Fights free radicals from pollution, sun, or stress—great for skin health and cellular protection
  • Gentle & Non-Habit Forming: Unlike sleep meds or strong relaxants, it won’t cause dependence—safe for long-term use
  • Dual Use: Internal & Topical: Works in supplements (for stress/sleep) and skincare (for anti-aging)—rarely do flavonoids pull off both!
  • Natural Sourcing: Most apigenin comes from organic chamomile (no synthetics)—fits “clean label” trends for supplements and beauty

Industry Applications

  1. Dietary Supplements
    • Sleep Support Capsules: Most common use—20-50mg per serving (paired with magnesium or L-theanine for deeper, more restful sleep; no morning grogginess)
    • Stress Relief Blends: Mixed with ashwagandha or chamomile extract (eases daily anxiety—great for busy professionals or students)
    • Antioxidant Stacks: Added to vitamin C/E supplements (boosts free-radical fighting—supports overall cellular health)
  1. Cosmetics & Skincare
    • Anti-Aging Serums: 0.1-0.5% concentration in facial serums (reduces fine lines and dullness—fights environmental damage from UV rays or pollution)
    • Calming Moisturizers: Mixed into sensitive-skin creams (soothes redness and irritation—perfect for rosacea or post-sun skin)
    • Eye Creams: Added to under-eye products (reduces dark circles and puffiness—calms tired eye skin)
  1. Functional Beverages
    • Sleep Teas/Tonics: Diluted in nighttime herbal teas (mixed with valerian or lemon balm—sips before bed for better sleep)
    • Stress-Relief Shots: Small doses (10-20mg) in “calm shots” (no caffeine—great for midday stress slumps)
    • Herbal Lattes: Stirred into decaf chamomile lattes (enhances the calming effect—cozy evening drink)
  1. Traditional Wellness Products
    • Herbal Tinctures: Used in chamomile tinctures (boosts the calming benefits—traditional use for mild insomnia)
    • Ayurvedic Blends: Included in Ayurvedic “relaxation” powders (paired with brahmi or jatamansi—fits holistic stress relief practices)
  1. Pet Wellness
    • Anxious Pet Supplements: Tiny doses (5-10mg) in dog/cat calming powders (eases separation anxiety or travel stress—safe for furry friends)
    • Pet Skincare: Mixed into pet paw balms (soothes dry, cracked paws—calms irritation from hot/cold surfaces)
  1. Pharmaceutical Research
    • Sleep Aid Studies: Used in labs to develop natural sleep meds (for folks who can’t take synthetic sleep drugs)
    • Skin Health Research: Investigated for its potential in anti-aging or anti-inflammatory skincare treatments (backed by early studies on its antioxidant effects)
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Apigenin: Trusted International Manufacturer & Supplier for Cosmetics, Dietary Supplements & Pharmaceuticals

If you are in the cosmetics, dietary supplements, food and beverage, or pharmaceutical industry and are looking for a reliable, high-quality source of Apigenin, you’ve come to the right place. This detailed guide covers everything B2B buyers need to know—from what apigenin is and its health benefits, to technical specifications, production processes, and why Shaanxi Zhonghong Biotechnology Co., Ltd. is your ideal global supplier and manufacturer.

1. What is Apigenin?

Apigenin is a natural flavonoid compound found in a variety of plants. It is renowned for its antioxidant, anti-inflammatory, and potential anticancer properties. As a bioactive ingredient, it is widely used in nutraceuticals, functional foods, cosmetics, and pharmaceutical formulations due to its strong biological activity and safety profile.

2. Source, Chemical Properties & Specifications

Apigenin is primarily extracted from plants such as chamomile, parsley, celery, and passionflower.

  • CAS Number: 520-36-5

  • Molecular Formula (MF): C₁₅H₁₀O₅

  • Molecular Weight (MW): 270.24 g/mol

  • EINECS: 208-292-3

Our apigenin is obtained through advanced extraction and purification technologies, ensuring high purity (typically >98%) and superior bioavailability.

3. Why Choose Our Apigenin? Key Benefits & Usage

Composition & Efficacy: Our apigenin is all-natural, non-GMO, and produced in compliance with international standards including ISO, HALAL, and KOSHER certifications.

Health Benefits:

  • Strong antioxidant activity

  • Supports cardiovascular and neurological health

  • Promotes relaxation and better sleep

  • Potential anti-tumor effects

Recommended Daily Intake: Typically ranges between 50–500 mg per day for adults, depending on application and formulation requirements.

Applicable Industries: Perfect for dietary supplements, functional food and beverages, cosmetics (e.g., anti-aging serums), pharmaceuticals, and health care products.

Usage: Can be formulated into tablets, capsules, powders, liquid extracts, and topical applications.

Precautions & Side Effects: Apigenin is generally considered safe. Excessive consumption may cause mild gastrointestinal discomfort. Pregnant or breastfeeding women should consult a healthcare provider before use.

4. Why Partner with Shaanxi Zhonghong Biotechnology?

We are a certified high-tech enterprise specializing in the R&D, production, and global distribution of plant extracts and bioactive compounds.

  • 28+ Years of Experience in botanical extract manufacturing

  • 5 University Joint-Labs and 20+ Patent Technologies

  • State-of-the-Art Equipment: HPLC, NMR, GC-MS ensuring purity >98% (20% higher than industry average)

  • Global Reach: Serving 80+ countries across Asia, Europe, and the Americas

We provide customized apigenin solutions tailored to specific industry needs—whether you are a pharmaceutical company, supplement brand, or cosmetic manufacturer.

5. Product Specification & COA

Below is a summary of our Certificate of Analysis (COA) for apigenin:

Category Item Standard Test Method
Pesticides Chlorpyrifos ≤0.01 ppm GC-MS
Cypermethrin ≤0.01 ppm HPLC
Heavy Metals Lead (Pb) ≤0.5 ppm ICP-MS
Arsenic (As) ≤0.3 ppm ICP-MS
Cadmium (Cd) ≤0.1 ppm ICP-MS
Microbiology Total Plate Count ≤1000 CFU/g USP <61>
Yeast & Mold ≤100 CFU/g USP <61>
E. coli Negative USP <62>

Full COA is available upon request.

6. Production Process

We use advanced extraction methods including supercritical CO2 extraction, solvent extraction, and column chromatography—ensuring high yield, purity, and bioactivity while minimizing environmental impact.

7. Application Scenarios

  • Nutraceuticals: Capsules and powders for antioxidant support

  • Cosmetics: Anti-aging, anti-inflammatory creams and serums

  • Functional Foods & Beverages: Health drinks and fortified foods

  • Pharmaceuticals: R&D for cancer and neuroprotective drugs

8. Quality Control

Every batch of apigenin undergoes rigorous testing through HPLC, NMR, and mass spectrometry. We adhere to cGMP and HACCP standards throughout production. Our quality team ensures traceability from raw material to finished product, providing you with consistent, reliable, and safe apigenin extract.

9. Packaging & Logistics

  • Packaging: 1kg/bag, 25kg/drum, or customized packaging

  • Storage: Keep in a cool, dry place away from light

  • Shipping: We support DDP, DAP, FOB, and CIF delivery terms with fast global logistics.

10. Research & Innovation

We continuously invest in R&D exploring new applications of apigenin in cancer therapy, neuroprotection, and cosmetic innovation. Our team is also developing novel formulations to enhance apigenin’s bioavailability and efficacy.

11. FAQ

Q: Is your apigenin organic?
A: We offer both conventional and organic-certified apigenin. Please specify your requirement.

Q: Can you supply free samples?
A: Yes, we provide free samples for qualified B2B clients.

Q: Can you customize formulations?
A: Absolutely. We specialize in custom extraction and blending based on client needs.

Q: What is the MOQ?
A: MOQ starts from 1kg for sample orders. Bulk order discounts are available.

Q: Where can I buy apigenin in bulk?
A: You can place orders directly through our website or contact our sales team.

12. How to Buy & Contact for Free Samples

Interested in trying our apigenin? Contact us for free samples and quotes:

We welcome OEM, ODM, and custom synthesis orders.

13. Conclusion

Apigenin is a powerful and versatile natural compound with growing demand across multiple industries. As a leading manufacturer, supplier, and exporter, Shaanxi Zhonghong guarantees top-quality apigenin with technical support, custom options, and reliable supply chain capability.

Reach out to us today to discuss your apigenin needs!

References:

  1. Zhang et al., “Apigenin in Cancer Therapy,” Molecules, 2021.

  2. Patel et al., “Antioxidant Effects of Apigenin,” Journal of Functional Foods, 2020.

  3. Shaanxi Zhonghong Internal Research & Analysis Reports.

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