Gypenoside: Premium Manufacturer & Global Supplier for Pharmaceutical and Nutraceutical Applications | Aiherba
Source high-purity Gypenoside from Zhonghong, a leading manufacturer and bulk supplier. Standardized for gypenosides. Request a free sample for your formulations and get a competitive price quote.
1. What is Gypenoside?
Gypenoside is a class of bioactive saponins extracted from Gynostemma pentaphyllum, a herb commonly known as “Jiaogulan” or “Southern Ginseng.” These compounds are the primary active ingredients responsible for the plant’s adaptogenic and health-promoting properties. For B2B clients in the pharmaceutical, nutraceutical, and cosmetic industries, Gypenoside offers a potent, scientifically backed ingredient for stress relief, metabolic health, and antioxidant formulations. Partnering with a reliable Gypenoside manufacturer ensures consistency, purity, and efficacy in your end products.
2. Source, Chemical Properties, and Identifiers
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Product Source: Extracted from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino.
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Primary Active Compounds: Gypenosides (e.g., Gypenoside XLIX, LV, XVII), with over 100 identified saponins.
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Standardization: Typically standardized to 80%, 90%, or 98% total gypenosides.
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CAS Number: 80206-82-2 (for Gypenoside extract)
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Molecular Formula (MF): Varies by specific gypenoside (e.g., C48H82O18 for Gypenoside XLIX)
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Molecular Weight (MW): Varies (e.g., 947.16 g/mol for Gypenoside XLIX)
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EINECS: N/A (complex herbal extract)
3. What Defines the Best Gypenoside? A B2B Buyer’s Guide
For international brands and exporters, the “best” Gypenoside is defined by its purity, standardization level, and the supplier’s ability to provide technical validation and compliance documentation.
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Key Ingredient & Efficacy: Premium Gypenoside is standardized to high purity (e.g., ≥98% total gypenosides). Its clinically supported benefits include:
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Adaptogenic & Stress-Relief Properties: Modulates cortisol levels and supports adrenal function.
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Cardiovascular & Metabolic Health: Helps regulate blood lipid levels and supports healthy blood pressure.
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Antioxidant & Anti-Inflammatory Effects: Reduces oxidative stress and inflammation markers.
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Liver Protection: Supports detoxification and liver cell regeneration.
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(Compliant for use in dietary supplements, pharmaceuticals, and functional foods.)
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Origin & Quality: Our Gynostemma pentaphyllum is sourced from organic farms in regions ideal for growth (e.g., Guangxi, China), ensuring high bioactive content.
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Usage & Dosage:
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Typical Use: Capsules, tablets, powders, functional beverages, and skincare products.
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Recommended Dosage: 100–500 mg daily for extracts standardized to ≥80% gypenosides. Dosage varies by application.
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Applicable Audience: Nutraceutical brands, pharmaceutical companies, cosmetic formulators, and functional food producers.
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Notes & Side Effects:
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Precautions: Generally safe. Avoid during pregnancy or if on blood-thinning medications.
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Side Effects: Rare; high doses may cause mild gastrointestinal discomfort.
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4. Why Partner with Zhonghong (Aiherba)?
Shaanxi Zhonghong Investment Technology Co., Ltd. (Global Marketing: Aiherba) is a certified high-tech enterprise and trusted exporter with 28 years of experience in bioactive plant extracts.
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Scientific Excellence: Joint labs with 5 top universities, 20+ patents, and a proprietary compound library.
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Advanced QC: HPLC, NMR, and GC-MS ensure purity standards exceed industry norms by 20%.
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Global Network: Supplies customized ingredients to 80+ countries for pharmaceuticals, nutraceuticals, and cosmetics.
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B2B Focus: Offers wholesale pricing, technical support, and customized herbal extract solutions.
5. Detailed Product Specifications (COA)
Category | Item Name | Specification | Test Method |
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Pesticide Residues | Chlorpyrifos | ≤0.2 mg/kg | GC-MS |
Cypermethrin | ≤0.5 mg/kg | GC-MS | |
Dichlorvos | ≤0.1 mg/kg | GC-MS | |
Heavy Metals | Lead (Pb) | ≤3.0 mg/kg | ICP-MS |
Arsenic (As) | ≤2.0 mg/kg | ICP-MS | |
Cadmium (Cd) | ≤1.0 mg/kg | ICP-MS | |
Mercury (Hg) | ≤0.1 mg/kg | ICP-MS | |
Microbiology | Total Plate Count | ≤1000 CFU/g | USP <61> |
Yeast & Mold | ≤100 CFU/g | USP <61> | |
E. Coli | Negative | USP <62> | |
Salmonella | Negative | USP <62> | |
Assay | Total Gypenosides | ≥98.0% | HPLC |
6. Production Process & Quality Control
Our Gypenoside extraction uses supercritical CO₂ and ethanol-water systems to preserve bioactive integrity. The process includes:
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Raw Material Selection: Organic Gynostemma pentaphyllum aerial parts.
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Extraction & Purification: Low-temperature extraction followed by chromatographic purification.
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Spray Drying: Converted into fine powder for enhanced stability.
Quality Control: Raw material authentication, in-process testing, and final HPLC analysis for gypenoside quantification. GC-MS screens pesticides; ICP-MS checks heavy metals. ISO-certified labs ensure compliance with USP, EP, and CP standards.
7. Application Scenarios
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Pharmaceuticals: Cardioprotective drugs, hepatoprotective agents.
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Nutraceuticals: Stress-relief supplements, metabolic health formulas.
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Cosmetics: Anti-aging creams (for antioxidant benefits).
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Functional Foods: Health beverages and powders.
8. Health Benefits, Research, and Innovation
Mechanism: Gypenosides activate AMPK and Nrf2 pathways, supporting metabolic health and antioxidant defense.
Research Frontiers: Synergistic formulations with ginseng or astragalus for enhanced adaptogenic effects.
Challenges: Improving bioavailability via liposomal or nanoemulsion technologies. Zhonghong’s R&D focuses on advanced delivery systems for optimal efficacy.
9. FAQ
Q: What is the MOQ for bulk orders?
A: MOQs start at 1 kg for R&D; wholesale discounts apply for larger orders.
Q: Can you customize the gypenoside ratio?
A: Yes, we offer customized herbal extract profiles for specific applications.
Q: Do you provide free samples?
A: Yes, qualified businesses can request a free sample for testing.
Q: Is the extract suitable for organic certification?
A: We offer conventional and organic options (USDA/ECOCERT compliant).
Q: What packaging is used?
A: Sealed foil bags with desiccant, inside cardboard drums for international shipping.
10. Where to Buy & Request Samples
Contact Us for Pricing & Samples:
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Email: sales@aiherba.com / liaodaohai@gmail.com
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Website: www.aiherba.com
11. Conclusion
For B2B clients in pharmaceuticals, nutraceuticals, and cosmetics, Gypenoside is a versatile, evidence-based active. Zhonghong (Aiherba) delivers premium, certified extracts with technical support and global logistics. Partner with us for customized solutions and competitive wholesale pricing.
12. References
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Journal of Ethnopharmacology: Gypenoside mechanisms in stress and metabolism.
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Phytomedicine: Clinical trials on cardiovascular benefits.
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USP, EP, and CP monographs for herbal extract testing.
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