Gypenoside
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Gypenoside

Gypenoside supplier bulk factory Wholesale Extract factory

  1. English Name: Gypenoside (it’s the main active compound from “Jiaogulan” herb—sometimes called “southern ginseng” in traditional use!)
  1. Specification
    • Purity: ≥ 98% (HPLC tested—super pure, no filler or herb bits left)
    • Solubility: Soluble in water and ethanol (mixes easy into supplements or herbal drinks)
    • Loss on Drying: ≤ 0.5% (stays dry, no clumping or losing potency)
    • Heavy Metals: ≤ 10 ppm (totally safe for oral use—no sketchy contaminants)
    • Active Marker: Standardized to key gypenoside fractions (so you get consistent benefits every time)
  1. Appearance: White to off-white powder with a mild, earthy herbal smell—zero chocolate aroma, obviously! It’s plain-looking but packs the herb’s key benefits.
  1. CAS NO.: N/A (it’s a family of saponin compounds, not a single chemical—so no one CAS number; individual gypenosides have their own, though)
  1. Lead time: 3-7 Working Days (we keep it in stock regularly, so we can ship it out fast—no long waits)
  1. Package: Small sizes: 1g/10g/100g glass vials (for small-batch supplements); bulk: 1kg aluminum foil bags or 25kg sealed drums (light-resistant to keep it fresh)
  1. Main Market: Europe, North America, Asia—anywhere people love natural herbal supplements for wellness
  1. Application Scenarios

Key Features

  • Herbal Wellness Staple: Used in traditional medicine (like Chinese and Korean) for ages—known for supporting overall balance
  • Gentle & Adaptogenic: Helps the body handle occasional stress without making you drowsy (great for busy lifestyles)
  • No Harsh Tastes: Mixes into drinks or capsules without a bitter aftertaste—way easier to take than some herbs
  • Natural & Plant-Based: Derived straight from Gynostemma herb, so it fits clean-label supplement lines
  • Stable in Formulas: Holds up well in powders, capsules, or liquid extracts—no fussy handling needed

Industry Applications

  1. Dietary Supplements
    • Herbal Capsules/Powders: Most common use—100-200mg per serving for daily wellness support (popular with folks into adaptogens)
    • Stress Relief Blends: Mixed with ashwagandha or bacopa for a calm, balanced vibe (no jitters or crashes)
    • Senior Wellness Formulas: Added to supplements for older folks—supports overall vitality in a gentle way
  1. Functional Beverages
    • Herbal Teas/Tonics: Tossed into herbal blends or “wellness shots” (dissolves easy, no weird flavor)
    • Adaptogen Drinks: Mixed into low-sugar energy drinks or plant-based smoothies—adds a subtle herbal boost
    • Traditional Elixirs: Used in modern takes on herbal tonics (stays true to its traditional roots)
  1. Herbal & TCM Products
    • TCM Formulations: A key ingredient in modern Traditional Chinese Medicine supplements—blended with other herbs for targeted benefits
    • Natural Wellness Lines: Perfect for brands focusing on “herbal-first” products (no synthetic additives)
  1. Sports Nutrition (Small-Scale)
    • Recovery Drinks: Small amounts added to post-workout smoothies—helps the body recover from exercise stress
    • Endurance Blends: Mixed into long-workout fuels (like gels) for steady energy without overstimulation
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Gypenoside: Premium Manufacturer & Global Supplier for Pharmaceutical and Nutraceutical Applications | Aiherba

Source high-purity Gypenoside from Zhonghong, a leading manufacturer and bulk supplier. Standardized for gypenosides. Request a free sample for your formulations and get a competitive price quote.

1. What is Gypenoside?

Gypenoside is a class of bioactive saponins extracted from Gynostemma pentaphyllum, a herb commonly known as “Jiaogulan” or “Southern Ginseng.” These compounds are the primary active ingredients responsible for the plant’s adaptogenic and health-promoting properties. For B2B clients in the pharmaceutical, nutraceutical, and cosmetic industries, Gypenoside offers a potent, scientifically backed ingredient for stress relief, metabolic health, and antioxidant formulations. Partnering with a reliable Gypenoside manufacturer ensures consistency, purity, and efficacy in your end products.

2. Source, Chemical Properties, and Identifiers

  • Product Source: Extracted from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino.

  • Primary Active Compounds: Gypenosides (e.g., Gypenoside XLIX, LV, XVII), with over 100 identified saponins.

  • Standardization: Typically standardized to 80%, 90%, or 98% total gypenosides.

  • CAS Number: 80206-82-2 (for Gypenoside extract)

  • Molecular Formula (MF): Varies by specific gypenoside (e.g., C48H82O18 for Gypenoside XLIX)

  • Molecular Weight (MW): Varies (e.g., 947.16 g/mol for Gypenoside XLIX)

  • EINECS: N/A (complex herbal extract)

3. What Defines the Best Gypenoside? A B2B Buyer’s Guide

For international brands and exporters, the “best” Gypenoside is defined by its purity, standardization level, and the supplier’s ability to provide technical validation and compliance documentation.

  • Key Ingredient & Efficacy: Premium Gypenoside is standardized to high purity (e.g., ≥98% total gypenosides). Its clinically supported benefits include:

    • Adaptogenic & Stress-Relief Properties: Modulates cortisol levels and supports adrenal function.

    • Cardiovascular & Metabolic Health: Helps regulate blood lipid levels and supports healthy blood pressure.

    • Antioxidant & Anti-Inflammatory Effects: Reduces oxidative stress and inflammation markers.

    • Liver Protection: Supports detoxification and liver cell regeneration.

    • (Compliant for use in dietary supplements, pharmaceuticals, and functional foods.)

  • Origin & Quality: Our Gynostemma pentaphyllum is sourced from organic farms in regions ideal for growth (e.g., Guangxi, China), ensuring high bioactive content.

  • Usage & Dosage:

    • Typical Use: Capsules, tablets, powders, functional beverages, and skincare products.

    • Recommended Dosage: 100–500 mg daily for extracts standardized to ≥80% gypenosides. Dosage varies by application.

  • Applicable Audience: Nutraceutical brands, pharmaceutical companies, cosmetic formulators, and functional food producers.

  • Notes & Side Effects:

    • Precautions: Generally safe. Avoid during pregnancy or if on blood-thinning medications.

    • Side Effects: Rare; high doses may cause mild gastrointestinal discomfort.

4. Why Partner with Zhonghong (Aiherba)?

Shaanxi Zhonghong Investment Technology Co., Ltd. (Global Marketing: Aiherba) is a certified high-tech enterprise and trusted exporter with 28 years of experience in bioactive plant extracts.

  • Scientific Excellence: Joint labs with 5 top universities, 20+ patents, and a proprietary compound library.

  • Advanced QC: HPLC, NMR, and GC-MS ensure purity standards exceed industry norms by 20%.

  • Global Network: Supplies customized ingredients to 80+ countries for pharmaceuticals, nutraceuticals, and cosmetics.

  • B2B Focus: Offers wholesale pricing, technical support, and customized herbal extract solutions.

5. Detailed Product Specifications (COA)

Category Item Name Specification Test Method
Pesticide Residues Chlorpyrifos ≤0.2 mg/kg GC-MS
Cypermethrin ≤0.5 mg/kg GC-MS
Dichlorvos ≤0.1 mg/kg GC-MS
Heavy Metals Lead (Pb) ≤3.0 mg/kg ICP-MS
Arsenic (As) ≤2.0 mg/kg ICP-MS
Cadmium (Cd) ≤1.0 mg/kg ICP-MS
Mercury (Hg) ≤0.1 mg/kg ICP-MS
Microbiology Total Plate Count ≤1000 CFU/g USP <61>
Yeast & Mold ≤100 CFU/g USP <61>
E. Coli Negative USP <62>
Salmonella Negative USP <62>
Assay Total Gypenosides ≥98.0% HPLC

6. Production Process & Quality Control

Our Gypenoside extraction uses supercritical CO₂ and ethanol-water systems to preserve bioactive integrity. The process includes:

  1. Raw Material Selection: Organic Gynostemma pentaphyllum aerial parts.

  2. Extraction & Purification: Low-temperature extraction followed by chromatographic purification.

  3. Spray Drying: Converted into fine powder for enhanced stability.

Quality Control: Raw material authentication, in-process testing, and final HPLC analysis for gypenoside quantification. GC-MS screens pesticides; ICP-MS checks heavy metals. ISO-certified labs ensure compliance with USP, EP, and CP standards.

7. Application Scenarios

  • Pharmaceuticals: Cardioprotective drugs, hepatoprotective agents.

  • Nutraceuticals: Stress-relief supplements, metabolic health formulas.

  • Cosmetics: Anti-aging creams (for antioxidant benefits).

  • Functional Foods: Health beverages and powders.

8. Health Benefits, Research, and Innovation

Mechanism: Gypenosides activate AMPK and Nrf2 pathways, supporting metabolic health and antioxidant defense.
Research Frontiers: Synergistic formulations with ginseng or astragalus for enhanced adaptogenic effects.
Challenges: Improving bioavailability via liposomal or nanoemulsion technologies. Zhonghong’s R&D focuses on advanced delivery systems for optimal efficacy.

9. FAQ

Q: What is the MOQ for bulk orders?
A: MOQs start at 1 kg for R&D; wholesale discounts apply for larger orders.

Q: Can you customize the gypenoside ratio?
A: Yes, we offer customized herbal extract profiles for specific applications.

Q: Do you provide free samples?
A: Yes, qualified businesses can request a free sample for testing.

Q: Is the extract suitable for organic certification?
A: We offer conventional and organic options (USDA/ECOCERT compliant).

Q: What packaging is used?
A: Sealed foil bags with desiccant, inside cardboard drums for international shipping.

10. Where to Buy & Request Samples

Contact Us for Pricing & Samples:

11. Conclusion

For B2B clients in pharmaceuticals, nutraceuticals, and cosmetics, Gypenoside is a versatile, evidence-based active. Zhonghong (Aiherba) delivers premium, certified extracts with technical support and global logistics. Partner with us for customized solutions and competitive wholesale pricing.

12. References

  • Journal of Ethnopharmacology: Gypenoside mechanisms in stress and metabolism.

  • Phytomedicine: Clinical trials on cardiovascular benefits.

  • USP, EP, and CP monographs for herbal extract testing.

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