Pure Fish Collagen Powder

Pure Fish Collagen Powder: Premium Marine Sourcing from Zhonghong Biotech (Free Samples Available)

1. What is Pure Fish Collagen Powder?
Pure Fish Collagen Powder, predominantly Type I collagen, is a hydrolyzed protein derived from the skin, scales, and bones of marine fish (e.g., Tilapia, Cod). This enzymatic hydrolysis process yields bioactive collagen peptides – low molecular weight fragments (typically 2,000-5,000 Da) with significantly enhanced bioavailability compared to native collagen. These peptides are rapidly absorbed into the bloodstream via the paracellular pathway and PepT1 transporter, facilitating targeted delivery to skin, joints, and connective tissues to stimulate endogenous collagen synthesis via fibroblast activation and modulation of TGF-β/Smad signaling pathways. Its superior solubility, neutral taste, and odorless profile make it ideal for nutraceutical and functional food applications.

2. Product Source, Chemical Properties & Identification

• Source: Sustainably sourced Marine Fish (Tilapia nilotica, Gadus morhua). Traceability protocols ensure origin compliance.

• CAS Number: 9007-34-5

• Molecular Formula (MF): Represents repeating amino acid sequences (primarily Gly-X-Y, where X & Y are often Pro and Hyp).

• Molecular Weight (MW): Hydrolyzed form: Typically 2,000 – 5,000 Daltons (Da).

• EINECS: 232-697-4

• Key Chemical Properties: High solubility (><｜begin▁of▁thinking｜> pH stability, rich in Glycine (~33%), Proline (~12%), Hydroxyproline (~10%) – crucial for triple-helix stability and biological activity. Exhibits characteristic FT-IR spectra (Amide I, II, III bands) and DSC thermograms.

3. Why Zhonghong Biotech’s Pure Fish Collagen is the Optimal Choice
Zhonghong Biotech sets the benchmark for premium Pure Fish Collagen Powder through rigorous science and quality:

• Premium Ingredients: 100% pure hydrolyzed fish collagen peptides. Non-GMO, Gluten-Free, Allergen-Free (BSE/TSE Free). No fillers or artificial additives.

• Clinically Validated Efficacy (Compliant): Supports skin dermal matrix integrity (increases elasticity, reduces wrinkles – in vivo studies), promotes chondrocyte proliferation and synovial fluid viscosity for joint comfort, enhances bone mineral density (Osteoblast stimulation), aids muscle protein synthesis (MPS), and supports gut mucosal barrier function.

• Optimal Daily Intake: Recommended dosage: 5g to 10g daily. Efficacy supported by clinical research (e.g., Proksch et al., 2014). Consult a physician for specific needs.

• Origin & Manufacturing: Sourced responsibly, processed in cGMP-certified facilities in China. Advanced enzymatic hydrolysis ensures optimal peptide profile.

• Usage: Easily soluble in hot/cold beverages, smoothies, yogurts, or baked goods. Ideal for capsules, tablets, and functional foods.

• Target Audience: Adults seeking skin health, joint support, athletes, seniors, individuals in wellness programs.

• Safety & Side Effects: Generally Recognized As Safe (GRAS). Well-tolerated. Potential mild gastrointestinal discomfort if taken in excessive doses initially.

• Critical Considerations: Verify Allergen Statements (fish source), ensure product has full Certificate of Analysis (CoA) confirming purity and safety (see below). Contraindicated for individuals with severe fish allergies.

4. Zhonghong Biotech: Your Trusted Collagen Partner
Zhonghong Biotech (Shaanxi Zhonghong Investment Technology Co., Ltd.) is a globally recognized leader in the research, development, and large-scale manufacturing (Bulk Supplier) of high-purity bioactive compounds. With 28 years of expertise in plant extraction and marine bioactives, we serve the chemical, material science, and life science sectors.

• Scientific Prowess: Collaboration with 5 elite universities fuels our 20+ patented technologies and exclusive global compound library, creating significant R&D barriers.

• Cutting-Edge Infrastructure: Equipped with HPLC (High-Performance Liquid Chromatography), UHPLC-MS (Ultra-HPLC-Mass Spectrometry), and 600MHz Superconducting NMR (Nuclear Magnetic Resonance). Our purity standards exceed industry norms by 20%+.

• Global Supply Chain Excellence: Our robust network delivers customized herbal extract and bioactive solutions to 80+ countries, serving multinational pharmaceutical companies, leading nutraceutical brands (Wholesale partners), and premier research institutions. We specialize in customized solutions tailored to specific application requirements.

5. Comprehensive Product Specifications & Certificate of Analysis (CoA)
Zhonghong guarantees transparency. Every batch undergoes stringent testing per international pharmacopeia (USP, EP).

Pure Fish Collagen Powder – Certificate of Analysis (CoA) Summary

6. Advanced Production Process: Precision Hydrolysis
Our optimized manufacturing ensures peak bioactivity:

1. Sustainable Sourcing & Prep: Raw fish by-products undergo rigorous veterinary inspection and controlled trimming/washing.

2. Demineralization & Defatting: Acid/alkali treatment removes minerals and lipids.

3. Enzymatic Hydrolysis: Specific proteolytic enzymes (e.g., Alcalase, Trypsin) cleave collagen under controlled T/pH/duration to yield target peptide profiles (<5kDa).

4. Multi-Stage Purification: Filtration (ultrafiltration/nanofiltration), ion-exchange, and activated carbon remove impurities, odors, and salts.

5. Sterilization & Drying: Terminal sterilization (where applicable) followed by spray drying (inlet/outlet temp control) or lyophilization for maximum stability.

6. Strict QC Release: Comprehensive testing per CoA specifications before packaging.

7. Diverse Application Scenarios

• Nutraceuticals: Capsules, tablets, stick packs, gummies for skin beauty, joint health, sports nutrition.

• Functional Foods & Beverages: Fortified protein drinks, dairy products, health bars, confectionery.

• Cosmeceuticals: Key active in anti-aging serums, creams, masks for dermal rejuvenation and moisture retention.

• Medical Nutrition: Supports tissue repair and wound healing formulations.

• Pet Nutrition: Joint and coat health supplements.

8. Rigorous Quality Control (QC) Protocol
Zhonghong’s QC is integrated throughout the product lifecycle. Starting from GMP-compliant raw material qualification (vendor audits, CoA review), we implement Process Analytical Technology (PAT) for real-time monitoring of critical parameters (pH, temp, peptide size via GPC/SEC) during hydrolysis. Our state-of-the-art Quality Control Laboratory, equipped with HPLC-DAD/ELSD/RID, ICP-MS, GC-MS/MS, UHPLC-QTOF-MS, and Microbiological suites, performs identity, purity, potency, and safety testing per validated methods aligned with ICH Q2(R1). Stability studies (ICH Q1A) ensure shelf-life. Batch traceability is enforced. Our ISO 9001:2015 and ISO 22000/FSSC 22000 certified systems guarantee consistent, safe, high-quality Pure Fish Collagen Powder meeting global regulatory standards (FDA, EFSA, Health Canada).

9. Secure Packaging & Global Logistics

• Packaging: Available in multi-layer foil bags (1kg, 5kg, 10kg) with desiccant, inside food-grade HDPE drums (25kg) or fiber drums (20kg). Custom packaging for bulk orders. Nitrogen flushing optional.

• Storage: Store in a cool (<25°C), dry place. Shelf life: 24 months unopened.

• Logistics: Efficient global shipping via air/sea freight. Expertise in export documentation and cold chain (if required). Compliant with IATA/IMDG regulations.

10. Deep Dive: Health Mechanisms, Applications & Innovation

• Health Mechanisms: Bioactive peptides (e.g., Pro-Hyp, Gly-Pro-Hyp) act as ligands for receptors on fibroblasts/chondrocytes, stimulating collagen I/III, elastin, and hyaluronic acid synthesis via MAPK/ERK and PI3K/Akt pathways. Exhibit antioxidant activity (radical scavenging), MMP inhibition, and modulate inflammatory cytokines (e.g., TNF-α, IL-1β).

• Industry Applications: Driving innovation in beauty-from-within supplements, osteoarthritis management, sarcopenia mitigation, wound healing biomaterials, and functional food fortification.

• Research & Challenges: Current focus on structure-activity relationship (SAR) of specific peptides, bioavailability enhancement (nano-delivery), sustainable sourcing (by-product valorization), and clinical validation for new indications (gut-brain axis, metabolic health). Challenges include standardization of bioactive peptide profiles and large-scale cost-effective production of specific sequences.

11. Frequently Asked Questions (FAQ)
Q1: What makes marine collagen better than bovine/porcine?
A1: Marine collagen (Type I) boasts superior bioavailability due to lower molecular weight peptides and is preferred for ethical/religious (halal/kosher potential) and safety (BSE-free) reasons. Often perceived as more sustainable.
Q2: How long to see results?
A2: Clinical studies show visible skin improvements (hydration, elasticity) often within 4-8 weeks of consistent use (5-10g/day). Joint benefits may take 8-12 weeks.
Q3: Is it safe during pregnancy/breastfeeding?
A3: Generally safe, but consult your physician before starting any new supplement.
Q4: Can vegetarians/vegans use this?
A4: No, as it’s derived from fish. Plant-based collagen boosters exist but do not provide direct collagen peptides.
Q5: Do you offer free samples?
A5: Yes! We provide free sample herbal extract of our Pure Fish Collagen Powder for qualified businesses. Contact us to request.
Q6: What customization options are available?
A6: We offer customized herbal extract solutions including specific peptide profiles (molecular weight distribution), flavor masking, instantization, and blends with other actives (e.g., Vitamin C, Hyaluronic Acid). Discuss your customized needs.
Q7: What is the minimum order quantity (MOQ)?
A7: Competitive MOQs for bulk and wholesale quantities. Contact sales for specific details based on your requirements.
Q8: Where can I buy?
A8: Contact Zhonghong Biotech directly for bulk, wholesale, and OEM inquiries. Visit our website for more information.

12. Where to Buy & Request Free Samples
Ready to source premium Pure Fish Collagen Powder? As a leading manufacturer and supplier, Zhonghong Biotech offers competitive prices for bulk quantities and wholesale partnerships.

• Get Your Free Sample: Experience the Zhonghong quality difference. Qualified businesses can request free sample herbal extract.

• Contact Us:

  • Email: sales@aiherba.com, liaodaohai@gmail.com

  • Website: www.aiherba.com

  • Inquiry Focus: Bulk Orders, Wholesale Pricing, Customization, Free Samples, OEM/ODM Services.

13. Conclusion
Pure Fish Collagen Powder represents a scientifically substantiated bioactive ingredient for enhancing skin, joint, and overall connective tissue health. Zhonghong Biotech leverages 28 years of expertise in bioactive extraction and purification, cutting-edge analytical technology (HPLC, NMR, MS), and a global distribution network to deliver a premium, high-purity, traceable marine collagen peptide product. Our commitment to quality control exceeding industry standards, customization capabilities, and provision of free samples establishes us as the trusted partner for nutraceutical brands, functional food developers, and wholesale distributors worldwide. Contact us today to discuss your collagen sourcing needs and explore partnership opportunities.

14. References

1. Proksch, E., et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. Skin Pharmacology and Physiology, 27(1), 47-55.

2. León-López, A., et al. (2019). Hydrolyzed Collagen—Sources and Applications. Molecules, 24(22), 4031.

3. Khatri, M., et al. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino Acids, 53(10), 1493-1506.

4. Song, H., et al. (2022). Bioactive collagen peptides: a review of their generation, bioactivities and applications. Journal of Functional Foods, 88, 104909.

5. ISO 3496:1994. Animal and vegetable fats and oils — Determination of hydroxyproline content.

6. USP-NF General Chapters: <61> Microbiological Examination, <232> Elemental Impurities, <561> Articles of Botanical Origin, <197> Spectrophotometric Identification Tests.

7. European Pharmacopoeia (Ph. Eur.) Monographs and General Chapters (e.g., 2.4.8 Heavy metals, 2.6.12/13 Microbiological examination).