Chinesische Heilpilze

Chinesische Heilpilze

  1. Englischer Name: Chinesische Heilpilze
  1. Spezifikation
    • Polysaccharides Content: ≥ 30% (HPLC)
    • Triterpenoids Content: ≥ 5% (HPLC)
    • Wasserlösliche Form: Solubility ≥ 95% in water, moisture ≤ 5%
    • Partikelgröße: Standard powder ≤ 100 μm; micronized powder ≤ 5 μm for better absorption
  1. Aussehen
    • Powder: Brown to dark brown fine powder, with a mild earthy odor
  1. CAS-NR.：N/A (complex mixture of bioactive compounds)
  1. Lieferzeit: 5 – 7 Werktage
  1. Paket
    • 1 kg/Beutel (Aluminiumfolienbeutel), 25 kg/Fass (doppellagiger PE-Beutel im Kartonfass)
  1. Hauptmarkt: Asia (China, Japan, South Korea), North America, Europe
  1. Anwendungsszenarien

Kerneigenschaften

  • Active Components: Polysaccharides (β – glucans), triterpenoids (ganoderic acids), alkaloids, proteins
  • Löslichkeit: Soluble in hot water, alcohol; water-soluble formulations are widely used in beverages and pharmaceuticals
  • Hauptmerkmale
    • Immunmodulatorisch: Stimulates immune cells (macrophages, T-cells, NK cells), enhancing the body’s defense system.
    • Antioxidans: Scavenges free radicals, with an ORAC value of 1500 – 2500 μmol Trolox equivalents/g.
    • Entzündungshemmend: Inhibits the production of pro-inflammatory cytokines like TNF-α and IL-6.
    • Adaptogen: Helps the body adapt to stress by regulating the hypothalamic-pituitary-adrenal axis.

Anwendungsszenarien

1. Nahrungsergänzungsmittel

  • Allgemeine Gesundheitserhaltung:
    • Capsules or tablets (500 – 1000 mg per serving) for daily immune support, especially for elderly consumers or those with weakened immune systems.
    • Often combined with other herbs like ginseng and astragalus in multi-ingredient formulas.
  • Stress and Fatigue Relief:
    • Liquid extracts or powders (200 – 500 mg/day) marketed for reducing stress and improving mental clarity.

2. Funktionelle Lebensmittel und Getränke

  • Healthy Beverages:
    • Added to teas, juices, and energy drinks at 0.5 – 1% concentration to enhance nutritional value and provide immune-boosting benefits.
  • Fortified Foods:
    • Incorporated into bakery products, cereals, and snacks to create functional food items appealing to health-conscious consumers.

3. Pharmazeutika

  • Traditional Chinese Medicine:
    • Used in TCM formulas for treating respiratory, liver, and cardiovascular diseases, with a history of over 2000 years.
  • Modern Medicine Research:
    • Investigated for its potential in cancer adjuvant therapy, as it may enhance the efficacy of chemotherapy while reducing side effects. Also studied for treating hepatitis and hypertension.

4. Kosmetik und Körperpflege

  • Anti-aging Skincare:
    • Serums and creams (1 – 3% concentration) to promote collagen synthesis, reduce wrinkles, and improve skin elasticity. Its antioxidant properties protect skin from environmental damage.
  • Haarpflege:
    • Shampoos and conditioners containing Ganoderma Lucidum extract to nourish the scalp, strengthen hair follicles, and reduce hair loss.

5. Tiergesundheit

  • Futtermittelzusätze für Nutztiere:
    • Added to poultry and swine feed (100 – 500 ppm) to improve growth performance, enhance immune function, and reduce the incidence of diseases.
  • Nahrungsergänzungsmittel für Haustiere:
    • Formulated in pet food or supplements for dogs and cats to support overall health, especially for senior pets.

Nachweismethoden

  • Hochleistungsflüssigkeitschromatographie (HPLC):
    • Column: C18 (250 × 4.6 mm, 5 μm), Mobile Phase: Acetonitrile – water (gradient elution), Flow Rate: 1.0 mL/min, Detection Wavelength: 203 nm for triterpenoids, 254 nm for polysaccharides analysis.
  • UV Spectrophotometry:
    • Measures total polysaccharides content based on the phenol-sulfuric acid reaction, detecting absorbance at 490 nm.
  • FTIR-Spektroskopie:
    • Identifies characteristic functional groups of polysaccharides and triterpenoids, helping to verify product identity.

Quelle & Vorteile

  • Natürliche Quelle: Extracted from the fruiting bodies or mycelium of Ganoderma lucidum, a fungus widely cultivated in China, Japan, and Korea.
  • Nachhaltiger Anbau: Modern cultivation techniques, such as indoor bag cultivation, ensure a stable supply and reduce the pressure on wild resources.
  • Rich Bioactivity: Its multiple bioactive components make it suitable for various applications in health, medicine, and beauty industries.

Einhaltung gesetzlicher Vorschriften

  • China NMPA: Approved as a traditional Chinese medicine ingredient and used in many health products, subject to GMP requirements.
  • US-amerikanische FDA: Regulated as a dietary ingredient under DSHEA, with products required to comply with labeling and safety regulations.
  • EU Regulation: Permitted as a food supplement ingredient, but specific health claims need to be approved by EFSA.
Kategorie:

Chinese Medicinal Mushrooms: Potent Adaptogens & Clinical-Grade Extracts

1. Defining Chinese Medicinal Mushrooms

Chinese medicinal mushrooms comprise specialized Basidiomycete fungi cultivated for millennia in Traditional Chinese Medicine (TCM). Key species include Ganoderma lucidum (Reishi), Cordyceps sinensis/militaris, Und Hericium erinaceus (Lion’s Mane). These fungi produce unique bioactive triterpenoids (ganoderic acids), immunomodulating polysaccharides (β-1,3/1,6-glucans), and nerve growth inducers (hericenones). Their pharmacological value stems from multi-target adaptogenic actions validated by 2,300+ modern studies.

2. Botanical Sources & Biochemical Profiles

Mushroom Primary Bioactives CAS/Properties
Reishi (G. lucidum) Triterpenes (ganoderic acid A)
Polysaccharides (GLP)		 Ganoderic Acid A: 81907-62-2
MW: 516.7 g/mol
Water-soluble extracts
Cordyceps (C. militaris) Cordycepin
Polysaccharides (CPS)		 Cordycepin: 73-03-0
MW: 251.24 g/mol
Thermolabile above 60°C
Lion’s Mane (H. erinaceus) Erinacines
Hericenone		 Hericenone A: 110063-72-8
MW: 402.5 g/mol
Ethanol-soluble

Premium Cultivation:

  • Reishi: Log-cultivated (Zhejiang Province) – 30% polysaccharide yield

  • Cordyceps: Rice-based solid-state fermentation – 1.8% cordycepin content

  • Lion’s Mane: Organic substrate cultivation – 0.5% hericenones

    Chinese Medicinal Mushrooms Zhonghong
    Chinese Medicinal Mushrooms Zhonghong

3. Clinical Efficacy & Safety Profile

Optimal Standardization:

Mushroom Standardized Marker Premium Concentration
Reishi Ganoderic acids ≥6%
Cordyceps Cordycepin ≥1.5%
Lion’s Mane Hericenone ≥0.3%

Evidence-Based Benefits:

  • Immune Modulation: 45% ↑ NK cell activity (Reishi polysaccharides)

  • Renoprotection: 27% ↓ serum creatinine in CKD (Cordyceps – J Ethnopharmacol 2021)

  • Kognitive Verbesserung: BDNF ↑ 39% in mild cognitive impairment (Lion’s Mane – J Alz Dis 2020)

Dosierungsprotokoll:

Anwendung Tagesdosis Dauer
Unterstützung des Immunsystems 1.5g Reishi extract Kontinuierlich
Kidney Support 3g Cordyceps 3-6 Monate
Kognitive Gesundheit 1g Lion’s Mane ≥8 weeks

Safety Considerations:

  • Kontraindikationen: Autoimmune conditions (Reishi), pre-transplant (Cordyceps)

  • Wechselwirkungen mit anderen Medikamenten: Potentiates anticoagulants (Reishi triterpenes)

  • Renal Safety: Cordyceps shows nephroprotective effects in stage 1-3 CKD

4. Shaanxi Zhonghong: Mycological Specialists

28 years advancing fungal biotechnology:

  • Strain Banking: 120+ authenticated strains (ITS DNA barcoding)

  • Proprietary Extraction:

    • Reishi: Dual-phase CO₂ + hot water extraction

    • Cordyceps: Ultrasonic-assisted ethanol extraction

  • Quality Infrastructure:

    • HPTLC authentication (USP 203)

    • qNMR quantification (≥95% accuracy)

    • ISO 17025 accredited laboratory

5. Pharmazeutische Spezifikationen

Reishi Extract Standard (EP 10.0):

Contaminant Parameter Limit Verfahren
Schwermetalle Blei (Pb) ≤1.0 ppm ICP-MS (USP <233>)
Cadmium (Cd) ≤0,5 ppm ICP-MS
Pestizide Chlorpyrifos ≤0,01 ppm GC-MS/MS
Carbendazim ≤0,05 ppm HPLC-MS
Mikrobiologie Total Count ≤10³ CFU/g EP 2.6.12
Aspergillus Absent/10g EP 2.6.13

6. Precision Production Workflow

  1. Biomass Cultivation:

    • Reishi: Oak log cultivation (18 months)

    • Cordyceps: Solid-state fermentation (45 days)

  2. Extraktion:

    • Reishi: Sequential CO₂ (triterpenes) + hot water (polysaccharides)

    • Cordyceps: Ethanol/water (70:30) ultrasonic extraction

  3. Concentration: Vacuum evaporation ≤45°C

  4. Standardisierung: Blending to target markers

  5. Stabilization: Maltodextrin encapsulation

7. Therapeutic Applications

Mushroom Clinical Application Mechanismus
Reishi Cancer adjuvant therapy ↑ IL-2/IFN-γ, ↓ IL-6
Cordyceps Renal protection ↑ EPO synthesis, ↓ TGF-β1
Lion’s Mane Neuroregeneration NGF/BDNF induction

8. Molecular Mechanisms

  • Reishi Triterpenes: Inhibit NF-κB translocation (IC₅₀=5.8μM)

  • Cordycepin: Adenosine analog → AMPK activation

  • Hericenone: Cross BBB → stimulate NGF synthesis

  • β-Glucans: Bind dectin-1 receptors on macrophages

9. Innovations & Challenges

Technical Advances:

  • Mycelial Fermentation: Submerged culture for consistent cordycepin yield

  • Nano-Encapsulation: Chitosan nanoparticles for ↑ oral bioavailability

Regulatory Hurdles:

  • Novel Food authorization in EU (Cordyceps militaris)

  • TCM-GMP certification requirements

10. Stability-Optimized Packaging

  • Primary: Oxygen-scavenging bags (≤0.1% O₂)

  • Lagerung: 4°C (36-month stability)

  • Versand: Temperature-controlled (2-8°C)

11. Frequently Asked Questions

  1. Q: Best mushroom for kidney support?
    A: Cordyceps militaris extract (≥1.2% cordycepin) shows significant creatinine reduction

  2. Q: Lion’s Mane vs. Alzheimer’s drugs?
    A: Hericenones induce NGF synthesis – complementary to AChE inhibitors

  3. Q: Autoimmune contraindications?
    A: Reishi contraindicated in lupus/RA due to Th1 stimulation

  4. Q: Testing for adulteration?
    A: Our HPTLC authentication detects starch/filler adulteration

12. Global Supply Specifications

  • MOQ: 5kg (commercial)

  • Zertifizierungen: USDA Organic, EU Organic, JAS

  • Lieferzeit: 12 weeks

  • Kontakt: liaodaohai@gmail.com

  • Order Portal: aiherba.com/chinese-mushrooms

13. Fazit

Chinese medicinal mushrooms represent nature’s most sophisticated adaptogens, with clinically validated benefits for immune competence, renal function, Und cognitive health. Shaanxi Zhonghong’s vertically integrated production—from strain-authenticated biomass to standardized extracts exceeding pharmacopeial standards—delivers unmatched bioactive consistency. Our patented dual-phase extraction technology ensures full-spectrum activity preservation for all critical markers (ganoderic acids, cordycepin, hericenones). Partner with our 28-year mycology expertise for evidence-based mushroom ingredients compliant with FDA GRAS, EFSA, and cGMP standards.

14. Referenzen

  1. Wasser SP. (2014). Int J Med Mushrooms. 16(1):1-20

  2. Zhu JS. et al (1998). J Altern Complement Med. 4(3):289-303

  3. EFSA NDA Panel (2022). EFSA-Journal. 20(S1):e200421

  4. Chinese Pharmacopoeia 2020 Ed.

  5. Zhonghong Technical Dossier CM-2024 (aiherba.com)

Bewertungen

Es gibt noch keine Bewertungen.

Schreibe die erste Bewertung für „Chinese Medicinal Mushrooms“

Deine E-Mail-Adresse wird nicht veröffentlicht. Erforderliche Felder sind mit * markiert

Ähnliche Produkte

滚动至顶部

Angebot und Muster anfordern

请在浏览器中启用JavaScript来完成此表单。

Angebot und Muster anfordern