,

Alpha-Arbutin

α-Arbutin supplier bulk factory Wholesale Extract factory

  1. Englischer Name: α-Arbutin,Alpha-Arbutin
  1. Spezifikation
    • General Powder: α-Arbutin ≥ 99% (HPLC), optical purity ≥ 98%
    • Water-soluble Powder: α-Arbutin ≥ 98% (HPLC), with a water-soluble Anbieter (e.g., cyclodextrin), solubility ≥ 100 g/L at 25°C
  1. Aussehen
    • General Powder: White crystalline powder, odorless
    • Water-soluble Powder: Off-white free-flowing powder
  1. CAS-NR.:84380-01-8
  1. Lieferzeit: 3 – 7 Werktage
  1. Paket
    • 1 kg/Beutel (Aluminiumfolienbeutel), 25 kg/Fass (doppellagiger PE-Beutel im Kartonfass)
  1. Hauptmarkt: Asia (insbesondere In Okay-beauty and J-beauty markets), North America, Europe
  1. Anwendungsszenarien

Kerneigenschaften

  • Molekulare Formula: C₁₂H₁₆O₇
  • Löslichkeit: Soluble in water, ethanol, and propylene glycol; the water-soluble formulation Exponate enhanced dissolution Geschwindigkeit
  • Schlüssel Optionen:
    • Potent tyrosinase inhibitor, blocking melanin synthesis Extra erfolgreich than β-Arbutin (IC₅₀ = 0.2 mM)
    • Antioxidant properties, verteidigen Poren und Haut from UV-induced oxidative stress
    • Stetig in sauren Situationen (Optimum pH 4 – 6), Jedoch degrades in alkaline environments or at übermäßig temperatures (> 60°C)

Anwendungsszenarien

1. Kosmetik & Privat Pflege

  • Poren und Haut Lightening Waren:
    • Serums and Essences: Allgemein formulated at 2 – 5% Fokus, Senkung dunkel spots, melasma, and post-inflammatory hyperpigmentation. Medizinisch Forschung gegenwärtig a 30% Rabatt in pigmentation after 8 weeks of use.
    • Sonnenschutzmittel: Added at 1 – 2% liefern jede Solar- Sicherheit and anti-pigmentation Vorteile, Stoppen UV-induced melanin Herstellung.
    • Whitening Lotions: Gemischt mit anders lebhaft Substanzen like niacinamide and hyaluronic acid, Fokussierung auf allgemein Poren und Haut brightening and hydration.
  • Anti-Älter werden Formulierungen:
    • Inhibits collagen degradation hervorgerufen durch freie Radikale, Senkung das Aussehen von vorteilhaft Stämme and wrinkles when included in anti-aging masks and Lotionen.

2. Verschreibungspflichtige Medikamente

  • Dermatological Therapies:
    • Verwendet in prescription-strength Lotionen (so viel wie 4% Fokus in some Bereiche) for treating extrem pigmentation Probleme erinnert an melasma and freckles.
    • Submit-surgical and post-peel Funktionen vorwegnehmen oder zurückschrauben post-treatment hyperpigmentation, typischerweise gemischt with vitamin E.

3. Zielgerichtet Mahlzeiten und Getränke

  • Oral Nahrungsergänzungsmittel:
    • Capsules or tablets containing 500 mg of α-Arbutin, typischerweise paired with vitamin C steigern collagen synthesis and promote Poren und Haut Wohlbefinden aus innen.
  • Magnificence Getränke:
    • Added to low-calorie Getränke at 0.5 – 1% Fokus, marketed as “beauty-from-within” Waren für allgemein Poren und Haut brightening.

4. Industriell Zwecke

  • Textile Dyeing:
    • Als rein mordant, α-Arbutin kann genutzt werden to repair dyes on Materialien, producing sanft Und stetig Färbung hues ohne mit harsh chemische Verbindungen.
  • Biopesticides:
    • Aqueous Optionen of α-Arbutin (0.1 – 0.5%) gegenwärtig antifungal properties, making it geeignet verwendet werden in eco-friendly agricultural pest Management.

Erkennung Strategien

  • ÜbermäßigEffizienz Flüssigkeitschromatographie (HPLC):
    • Säule: C18 (250 × 4,6 mm, 5 μm), Mobilfunk Abschnitt: Acetonitrile – Water (15:85, v/v), Strom Aufladung: 1.0 mL/min, Detection Wavelength: 280 nm
  • Massenspektrometrie (MS):
    • Gebraucht to verify die molekulare Konstruktion and purity, insbesondere for pharmaceutical-grade α-Arbutin Waren.
  • Differential Scanning Calorimetry (DSC):
    • Determines the melting Ebene (195 – 198°C for α-Arbutin), dienen zu Zu bestätigen Produkt hohe Qualität and authenticity.

Liefern und Vorteile

  • Herstellung: In erster Linie synthesized mittels enzymatic or chemical processes, Bereitstellung größer purity and consistency im Vergleich zu rein Extraktion Strategien.
  • Wirksamkeit: Es ist robust hemmend Auswirkungen on tyrosinase Angebote speedy and visual endet in Poren und Haut lightening, making it a am beliebtesten ingredient for high-end Pracht Waren.
  • Sicherheit: Typischerweise well-tolerated by most Poren und Haut Sorten, with a verringern Gefahr of irritation im Vergleich zu another 美白 Makler.

Einhaltung gesetzlicher Vorschriften

  • China NMPA: Permitted as a Schönheit ingredient with a am meisten Fokus von zwei% (requiring Sicherheit Auswertung für größer Bereiche).
  • EU Schönheit Regulation (EC 1223/2009): Accredited verwendet werden in cosmetics, with a beschränken of three% in leave-on Waren.
  • US-amerikanische FDA: Tentatively labeled as an OTC ingredient for Poren und Haut lightening, with Fokus Grenzen darunter Bewertung.

Alpha-Arbutin: The Gold Normal in Pores and skin Lightening and Antioxidant Safety| Supplier & Manufacturer

1. What is Alpha-Arbutin?

Alpha-arbutin is a glycosylated hydroquinone spinoff famend for its potent pores and skin – lightening properties. In contrast to its counterpart, beta – arbutin, alpha – arbutin displays a better affinity for tyrosinase, the important thing enzyme concerned in melanin synthesis. This makes it simpler at decreasing hyperpigmentation, comparable to age spots, freckles, and melasma, with out inflicting important pores and skin irritation. Extensively used within the cosmetics business, alpha – arbutin has additionally proven antioxidant and anti – inflammatory results, positioning it as a multifunctional bioactive ingredient.

Alpha-Arbutin Applications
Alpha-Arbutin Purposes

2. Product Origin and Chemical Properties

2.1 Supply

Alpha-arbutin could be extracted from varied crops, together with bearberry (Arctostaphylos uva-ursi), blueberries (Vaccinium spp.), and cranberries (Vaccinium macrocarpon). Nevertheless, as a result of low pure content material in crops, most business alpha – arbutin is produced by way of biocatalysis or chemical synthesis. At Shaanxi Zhonghong Investment Technology Co., Ltd., we make the most of superior biocatalytic processes to make sure excessive – purity, sustainable manufacturing with minimal environmental influence.

2.2 Chemisches Profil

  • CAS-Menge: 84380 – 01 – 8
  • Molekularformel (MF): C₁₂H₁₆O₇
  • Molekulargewicht (MW): 272.25 g/mol
  • EINECS: 282 – 776 – 3
  • Bodily State: White to off – white crystalline powder
  • Löslichkeit: Soluble in water (5 – 10 g/L at 25°C), barely soluble in ethanol

3. Optimum Product, Well being Benefits, Dosage, Precautions and Aspect Results

3.1 Finest Merchandise and Content

The best – high quality alpha – arbutin merchandise sometimes have a purity of 98% or increased. Our firm leverages state – of – the – artwork purification methods, comparable to excessive – efficiency liquid chromatography (HPLC) and crystallization processes, to realize a purity stage 20% above the business common. This ensures most efficacy in pores and skin – lightening purposes and minimizes the danger of impurities inflicting antagonistic reactions.

3.2 Well being Benefits

3.2.1 Pores and skin Lightening

Alpha-arbutin inhibits tyrosinase exercise, blocking the conversion of tyrosine to melanin. By decreasing melanin manufacturing, it successfully lightens current darkish spots and prevents new pigmentation, resulting in a extra even pores and skin tone.

3.2.2 Antioxidant Safety

It acts as a free – radical scavenger, neutralizing reactive oxygen species (ROS) comparable to hydroxyl and superoxide radicals. This antioxidant property helps defend pores and skin cells from oxidative harm, which is related to untimely ageing, effective strains, and wrinkles.

3.2.3 Anti – Inflammatory Results

Alpha-arbutin can cut back the manufacturing of professional – inflammatory cytokines, soothing irritated pores and skin and selling a more healthy pores and skin barrier perform. This makes it appropriate for delicate pores and skin sorts vulnerable to irritation.

3.3 Beneficial Dosage

In beauty formulations, the standard focus of alpha – arbutin ranges from 0.5% to 2%. For direct software merchandise like serums or lotions, making use of a pea – sized quantity (roughly 1 – 2 grams) containing the suitable focus to the affected pores and skin areas a couple of times every day is widespread. Nevertheless, it is vital to comply with product – particular directions.

3.4 Precautions and Aspect Results

Alpha-arbutin is mostly nicely – tolerated. Nevertheless, in uncommon instances, it might trigger delicate pores and skin irritation, comparable to redness or itching, particularly in people with extremely delicate pores and skin. Extended publicity to daylight can cut back its effectiveness and enhance the danger of pores and skin harm, so sunscreen use is advisable when utilizing alpha – arbutin merchandise. Keep away from contact with eyes, and if unintended ingestion happens, search medical recommendation instantly.

4. Firm Introduction

With 28 years of expertise within the bioactive compound business, Shaanxi Zhonghong Investment Technology Co., Ltd. is a number one excessive – tech enterprise. Our operations span agile analysis and improvement, collaborative innovation, built-in manufacturing, and international advertising and marketing, serving the chemical, supplies, and life science sectors.
  • Analysis Edge: Our partnerships with 5 prime – tier universities by way of joint laboratories, together with over 20 patented applied sciences and a singular international compound library, drive steady innovation in alpha – arbutin manufacturing and software.
  • Technological Superiority: Outfitted with state – of – the – artwork services, together with excessive – efficiency liquid chromatography (HPLC) and superconducting nuclear magnetic resonance spectrometers, we guarantee product purity requirements 20% increased than the business common.
  • Welt erreichen: Our intensive community covers greater than 80 nations throughout Asia, Europe, and the Americas. We provide custom-made uncooked materials options for multinational pharmaceutical firms, analysis establishments, and beauty producers.

5. Produktspezifikationen

Venture
Name
Indikator
Erkennungstechnik
Pestizidrückstände
Chlorpyrifos
< 0,01 ppm
Gasoline Chromatography – Mass Spectrometry (GC – MS)
Cypermethrin
< 0,02 ppm
GC – MS
Carbendazim
< 0,05 ppm
Excessive – Efficiency Liquid Chromatography – Mass Spectrometry (HPLC – MS/MS)
Schwermetalle
Blei (Pb)
< 0,5 ppm
Induktiv gekoppeltes Plasma – Massenspektrometrie (ICP – MS)
Quecksilber (Hg)
< 0,01 ppm
Chilly Vapor Atomic Absorption Spectroscopy (CVAAS)
Cadmium (Cd)
< 0,05 ppm
ICP – MS
Mikrobielle Kontamination
Gesamte lebensfähige Abhängigkeit
< 100 KBE/g
Normal microbiological plating methods
Escherichia coli
Abwesend
Polymerase-Kettenreaktion (PCR) und Plattierung
Salmonellen
Abwesend
PCR und Plattierung
Listeria monocytogenes
Abwesend
PCR und Plattierung

6. Herstellungsprozess

  1. Uncooked Materials Preparation: For biocatalytic manufacturing, choose excessive – high quality enzymes or microorganisms with excessive exercise for alpha – arbutin synthesis. Guarantee correct cultivation and activation of those organic catalysts.
  1. Biocatalysis or Chemical Synthesis: In biocatalysis, use enzymes to catalyze the response between hydroquinone and glucose to kind alpha – arbutin. In chemical synthesis, rigorously management response situations comparable to temperature, pH, and response time to advertise the formation of alpha – arbutin whereas minimizing by – product technology.
  1. Reinigung: Make use of a number of purification steps, together with filtration, extraction, and chromatography. HPLC is used to separate alpha – arbutin from impurities, guaranteeing excessive – purity product. Crystallization processes might also be utilized to additional refine the product.
  1. Drying and Formulation: Dry the purified alpha – arbutin beneath managed situations to take away moisture. Then, formulate it into completely different varieties in keeping with buyer necessities, comparable to effective powders, granules, or pre – blended options for cosmetics.
  1. High quality Inspection: Conduct complete high quality testing on the completed product, together with purity willpower, identification, and inspection of pesticide residues, heavy metals, and microbial contamination.

7. Anwendungsszenarien

7.1 Cosmetics

  • Pores and skin – Lightening Merchandise: Alpha-arbutin is a key ingredient in serums, lotions, masks, and lotions designed to cut back hyperpigmentation and obtain a brighter, extra even complexion.
  • Anti – Growing old Formulations: Mixed with different antioxidants and anti – ageing substances, it helps fight oxidative stress and enhance pores and skin texture, decreasing the looks of effective strains and wrinkles.
  • Sunscreen and After – Solar Care: Its antioxidant properties make it appropriate for inclusion in sunscreens to boost UV safety and in after – solar merchandise to appease solar – broken pores and skin.

7.2 Prescribed drugs (Analysis – based mostly)

At the moment, alpha – arbutin is beneath investigation for potential purposes in treating pores and skin illnesses associated to irregular pigmentation, comparable to melasma and publish – inflammatory hyperpigmentation. Its anti – inflammatory and antioxidant results might also contribute to wound – therapeutic analysis.

8. Qualitätsmanagement

High quality management is the cornerstone of our alpha – arbutin manufacturing. On the uncooked materials stage, we conduct strict inspections on enzymes, microorganisms, or chemical precursors, verifying their purity and exercise by way of biochemical assays and spectroscopic evaluation. Through the manufacturing course of, actual – time monitoring of response parameters (temperature, pH, response time) ensures constant product high quality. Within the purification part, HPLC is used for exact separation and purity willpower, with every batch of merchandise present process a number of rounds of study to make sure the absence of impurities. For ultimate product inspection, we carry out complete exams on chemical purity, microbial security, and heavy metallic content material, adhering to strict worldwide requirements. Our high quality management laboratory is licensed to ISO 9001 and follows Good Manufacturing Follow (GMP) pointers. By implementing a multi – step high quality management system, we assure that each batch of alpha – arbutin meets the very best high quality and security necessities, offering dependable merchandise to our prospects worldwide.

9. Packaging and Logistics

  • Verpackung: Our alpha – arbutin merchandise are packaged in air – tight, moisture – resistant containers. For small orders, we use aluminum foil luggage or amber glass bottles, whereas for bulk orders, fiber drums are utilized. Every bundle is labeled with detailed data, together with product identify, batch quantity, purity, expiration date, and storage directions.
  • Lagerung: Retailer in a cool, dry place, away from direct daylight, at temperatures between 2 – 8°C. Below correct storage situations, the shelf lifetime of our alpha – arbutin merchandise can attain as much as 36 months.
  • Transport: We accomplice with dependable worldwide logistics suppliers to make sure quick and safe supply. Samples could be shipped through specific providers like DHL or FedEx inside 3 – 5 enterprise days, whereas bulk orders are transported by sea or air freight in keeping with buyer necessities.

10. Well being Efficacy Analysis, Industrial Application Innovation, and Challenges

10.1 Analysis Frontiers

  • Nano – Supply Techniques: Scientists are exploring nanoencapsulation methods to enhance the steadiness and bioavailability of alpha – arbutin, enabling higher penetration into the pores and skin and extra focused supply.
  • Mixture Therapies: Analysis is underway to research the synergistic results of alpha – arbutin when mixed with different pores and skin – lively substances, comparable to vitamin C and niacinamide, for enhanced pores and skin – lightening and anti – ageing outcomes.

10.2 Herausforderungen

  • Stabilität: Alpha-arbutin could be unstable beneath sure situations, comparable to excessive temperature or publicity to gentle. Creating extra secure formulations with out compromising its efficacy stays a problem.
  • Einhaltung gesetzlicher Vorschriften: As a beauty ingredient, alpha – arbutin should adjust to varied worldwide rules relating to security, labeling, and efficacy claims. Guaranteeing constant compliance throughout completely different markets is essential for its widespread adoption.

11. Häufig gestellte Fragen

11.1 The place can I purchase Alpha-Arbutin?

  • We provide quite a lot of alpha – arbutin merchandise with completely different purity ranges and packaging choices to satisfy various buyer wants.

11.2 Is Alpha-Arbutin secure for all pores and skin sorts?

Alpha-arbutin is mostly secure for many pores and skin sorts. Nevertheless, people with extremely delicate pores and skin could expertise delicate irritation. It is advisable to carry out a patch check earlier than utilizing new merchandise containing alpha – arbutin.

11.3 Can Alpha-Arbutin be used throughout being pregnant?

There may be restricted analysis on the security of alpha – arbutin throughout being pregnant. Pregnant or nursing girls ought to seek the advice of a health care provider earlier than utilizing merchandise containing alpha – arbutin.

11.4 How lengthy does it take to see outcomes?

Seen pores and skin – lightening outcomes could take 4 – 8 weeks of constant use, because the pores and skin’s pure renewal cycle wants time to exchange pigmented cells with new, lighter – coloured ones.

12. Fazit

Alpha-arbutin stands as a revolutionary ingredient within the magnificence and skincare business, providing efficient pores and skin – lightening, antioxidant, and anti – inflammatory advantages. As a number one producer, Shaanxi Zhonghong Investment Technology Co., Ltd. is dedicated to offering excessive – high quality alpha – arbutin merchandise, backed by superior expertise, strict high quality management, and intensive international attain. Whether or not for creating modern beauty merchandise or advancing dermatological analysis, our alpha – arbutin choices set the usual for excellence.

13. Referenzen

  1. Kameyama, Okay., et al. (1995). Alpha – arbutin: A novel reversible tyrosinase inhibitor from the leaves of Vaccinium ashei. Zeitschrift für Agrar- und Lebensmittelchemie, 43(11), 2807 – 2810.
  1. Wang, Y., et al. (2018). Advances within the manufacturing and software of arbutin. Moleküle, 23(6), 1461.
  1. European Fee. (2019). Beauty Substances Database (CosIng). Retrieved from [CosIng official website]

评价

目前还没有评价

Nur angemeldete Kunden, die dieses Produkt gekauft haben, dürfen eine Bewertung abgeben.

滚动至顶部

Angebot und Muster anfordern

请在浏览器中启用JavaScript来完成此表单。

Angebot und Muster anfordern