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Polysacharid Ganoderma lucidum

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Ganoderma lucidum Polysaccharide factory supplier bulk Wholesale Extract factory

  1. Anglický název: Ganoderma lucidum Polysaccharide (fancy name for the key active stuff in Reishi mushrooms—you might hear it called “Reishi polysaccharide” for short!)
  1. Specifikace
    • Obsah polysacharidů: ≥ 30% (HPLC tested—this is the main beneficial component we’re after)
    • Rozpustnost: Dissolves easily in water (perfect for mixing into drinks, soups, or supplement powders)
    • Vlhkost: ≤ 5% (keeps it dry and free-flowing—no clumpy messes)
    • Těžké kovy: ≤ 10 ppm (zcela bezpečné pro orální užití – splňuje přísné normy pro potraviny/wellness)
    • Čistota: No additives or fillers—just pure polysaccharides from Reishi mushrooms
  1. Vzhled: Light yellow to off-white powder with a mild, earthy mushroom smell—rozhodně no chocolate aroma! It’s subtle, so it doesn’t overpower whatever you mix it into.
  1. ČÍSLO CAS: N/A (it’s a mix of natural polysaccharide compounds from Reishi, not a single chemical—so no one specific CAS number)
  1. Dodací lhůta: 3-7 Working Days (we keep it in stock regularly, so you won’t wait long to get it)
  1. Balík: Small sizes: 100g/1kg aluminum foil bags (great for small-batch supplements or home use); bulk: 25kg sealed drums (food-grade lined—locks in freshness and potency)
  1. Hlavní trh: Europe, North America, Asia—anywhere people love natural mushroom-based wellness products
  1. Scénáře aplikací

Klíčové vlastnosti

  • Reishiina „superschopnost“: The main reason Reishi’s been used in traditional medicine (like TCM) for centuries—known for supporting overall wellness
  • Gentle & Adaptable: Works well for most people, even daily—no harsh side effects
  • Všestranné kombinování: Blends smoothly into liquids or powders without changing the taste too much (unlike some strong herbs)
  • Přírodní a čisté: Derived straight from organic or high-quality Reishi mushrooms—fits “clean label” products perfectly
  • Stabilní skladování: Stays potent for months if kept in a cool, dry place—no fancy storage needed

Průmyslové aplikace

  1. Doplňky stravy
    • Kapsle/prášky s reishi: Most common use—500-1000mg per serving for daily wellness support (popular with folks into holistic health)
    • Mushroom Blend Supplements: Mixed with other mushroom extracts (like Chaga or Lion’s Mane) for a “super mushroom” boost
    • Vzorce na podporu imunity: Added to vitamins or wellness blends—thanks to its reputation for supporting immune health
  1. Funkční potraviny a nápoje
    • Mushroom Drinks: Tossed into Reishi lattes, herbal teas, or plant-based smoothies (dissolves fast, no grit)
    • Wellness Soups/Broths: Mixed into mushroom broths or nourishing soups—adds benefits without altering flavor
    • Snack Bars: Included in granola bars or protein bars (small amounts) for an extra wellness kick
  1. Tradiční wellness produkty
    • TCM formulace: A key ingredient in modern Reishi tinctures, teas, or herbal blends—stays true to its traditional roots
    • Eastern Wellness Lines: Popular in products for stress relief or “balance” (since Reishi’s often called the “mushroom of immortality” for a reason!)
  1. Specializovaná výživa
    • Wellness pro seniory: Added to meal replacements or easy-to-swallow supplements—supports overall vitality for older folks
    • Athlete Recovery: Mixed into post-workout shakes (small doses) for gentle recovery support
    • Veganské/rostlinné produkty: A go-to for vegan wellness lines—no animal products, just pure mushroom goodness

Ganoderma Lucidum Polysaccharides: The Final Immune Modulator for Well being and Longevity

1. What Are Ganoderma Lucidum Polysaccharides?

Ganoderma lucidum polysaccharides (GLPs) are bioactive β-D-glucans extracted from the fruiting our bodies, mycelia, or spores of Ganoderma lucidum (Reishi mushroom). Structurally, they comprise β-(1→3)-D-glucan backbones s β-(1→6)-D-glucosyl branches, forming triple-helix configurations vital for immunomodulatory exercise. With molecular weights starting from 10–1,000 kDa, these heteropolysaccharides comprise glucose, galactose, mannose, and xylose residues. Their distinctive helical conformation allows potent binding to immune cell receptors (e.g., dectin-1, TLR-4), triggering cytokine cascades and macrophage activation369.


2. Dodávka, chemické vlastnosti a technické specifikace

Botanické zdroje a extrakce

  • Hlavní napájení: Fruiting our bodies of Ganoderma lucidum nebo G. sinense (highest GLP content material: 1.8–2.5% dry weight)39.

  • Strategie extrakce:

    • Sizzling water extraction (95°C, 3h) → ethanol precipitation → deproteinization (Sevag reagent)

    • Ultrasonic-assisted extraction (40 kHz) → macroporous resin (AB-8) purification → lyophilization

Chemical Identification

Vlastnictví Hodnota
Číslo CAS Not assigned (advanced combination)
Molekulární vzorec (C₆H₁₀O₅)ₙ
Molekulová hmotnost 10–1,000 kDa
EINECS Not relevant
Vzhled Mild brown hygroscopic powder
Rozpustnost Water-soluble; insoluble in ethanol
Key Bioactivity β-(1→3)/(1→6) glycosidic bonds ≥85%

3. Přínosy pro zdraví, optimální dávkování a bezpečnost

Validated Therapeutic Results

  • Imunomodulace:

    • ↑ Macrophage phagocytosis by 300% and ↑ NK cell cytotoxicity by 150% by way of TLR4/NF-κB pathway activation39.

  • Antitumor Exercise:

    • Vyvolává apoptosis in HepG2 cells (IC₅₀: 50 μg/mL) by way of caspase-3 activation and Bcl-2 suppression69.

  • Metabolická regulace:

    • ↓ Fasting blood glucose by 32% in diabetic fashions by way of AMPK/GLUT4 signaling9.

  • Hepatoprotekce:

    • Snižuje ALT/AST ranges by 65% in ethanol-induced liver damage fashions3.

Návrhy na dávkování

  • Obecné zdraví: 100–300 mg/day (20–30% GLPs)

  • Terapeutické použití:

    • Immune help: 500 mg/day (≥40% GLPs)

    • Adjuvant most cancers remedy: 1,000–1,500 mg/day

  • Security Threshold: ≤3,000 mg/day (no noticed toxicity)9.

Vital Precautions

  • Autoimmune Circumstances: Might overstimulate Th1 responses (keep away from in lupus/RA).

  • Chirurgický zákrok: Discontinue 2 weeks pre-operation (potential immunostimulatory results).

  • Lékové interakce: Might potentiate immunosuppressants (e.g., cyclosporine).


4. Firm Introduction: Shaanxi Zhonghong Biotechnology Co., Ltd.

28-year pioneer in bioactive polysaccharide manufacturing, Shaanxi Zhonghong integrates proprietary extraction tech with international provide chain excellence to ship cGMP-grade GLPs exceeding pharmacopeial requirements.

Základní schopnosti:

  • Patentově chráněná extrakce: 20+ patents overlaying ultrasonic-microwave synergy (CN201810023456.7).

  • Analytická důslednost: HPLC-ELSD, 800MHz NMR, MALDI-TOF MS making certain Čistota >99,51 TP3T (exceeding USP/EP monographs).

  • Mezinárodní shodaCertifikace ISO 9001, FDA-GMP, EFSA, JECFA.

  • Zajistěte zvládnutí řetězceLogistika chladírenského řetězce ve více než 80 zemích.


5. Product Specs: Pharmaceutical-Grade GLP QC

Contaminant Testing Requirements

Třída Parametr Omezit Zkontrolujte techniku
Pesticidy Chlorpyrifos ≤0,01 ppm GC-MS/MS (EU 396/2005)
Glyfosát ≤0,05 ppm HPLC-MS/MS (ISO 16308)
Těžké kovy Olovo (Pb) ≤0,5 ppm ICP-MS (USP <233>)
Arsen (As) ≤0,5 ppm AAS (EP 2.4.27)
Mikrobiologie Závisí na celém talíři ≤1 000 KTJ/g USP <61>
E. coli Nepřítomný ISO 16654
Salmonela druhů Nepřítomný FDA BAM Kapitola 5

6. Vynikající výrobní postup

  1. Sourcing: Natural G. lucidum fruiting our bodies (OOP-certified).

  2. Extrakce: Dynamic maceration (95°C, pH 6.8, 3h) → ultrafiltration (100 kDa MWCO).

  3. Deproteinization: Sevag reagent (chloroform:butanol 4:1).

  4. Čištění: DEAE-Sepharose FF chromatography → lyophilization.

  5. Standardizace: Phenol-sulfuric acid assay to 40% GLP content material.


7. Účely v různých odvětvích

  • Nutraceutika: Immune-boosting capsules (GLP + β-glucan synergy).

  • Léky na předpis: Chemotherapy adjuvants (reduces cisplatin nephrotoxicity).

  • Kosmeceutika: Anti-aging serums (↑ collagen synthesis by 200%).

  • Useful Meals: Glycemic management drinks (GLP + berberine).


8. High quality Management: 360° Assurance Protocol

GLP batches bear čtyřfázové ověření:

  1. Potvrzení totožnosti: FT-IR spectral match (3,400 cm⁻¹ O-H; 1,070 cm⁻¹ C-O-C).

  2. Kvantifikace čistoty: HPSEC-ELSD (ICH Q2(R1)-validated; LOD: 0.05%).

  3. Testování bioaktivity:

    • RAW 264.7 macrophage NO manufacturing: ≥50% stimulation at 100 μg/mL

    • α-Glucosidase inhibition: IC₅₀ ≤ 2 mg/mL

  4. Stabilita: 24-month shelf-life underneath 25°C/60% RH (ICH Q1A(R2)).


9. Analýza hranic a výzev

  • Mechanistické poznatky:

    • Intestine microbiota modulation (↑ Bifidobacterium ↑ SCFA manufacturing).

    • STING pathway activation for antitumor immunity.

  • Medical Translation:

    • Part II trials for GLP-COVID-19 immunity synergy.

  • Technical Boundaries:

    • Perorální biologická dostupnost: Chitosan nanoparticles to reinforce absorption from 12% to 91%.

    • Structural Heterogeneity: Batch-to-batch reproducibility optimization.

  • Udržitelnost:

    • Mycelial fermentation to preserve wild Ganoderma populations.


10. Často kladené otázky: Kvalifikovaná řešení

Q: Can GLPs change chemotherapy?
A: No. Use as adjuvant remedy—enhances NK cell exercise with out interfering with cisplatin9.

Q: Secure throughout being pregnant?
A: Restricted information. Keep away from until authorized by a doctor.

Q: Why select 40% vs 95% GLPs?
A: 40% extracts swimsuit useful meals; 95%+ grades goal pharmaceutical purposes.

Otázka: Optimální doba spotřeby?
A: Morning on empty abdomen (enhances macrophage uptake).


The place to Purchase Pharmaceutical-Grade GLPs

🔬 Přímý příkaz od Shaanxi Zhonghong:


Závěr

Ganoderma lucidum polysaccharides redefine precision immunonutrition—with sturdy proof supporting roles in oncology, virology, and metabolic well being. For innovators in search of licensed, traceable GLPs, Shaanxi Zhonghong delivers unparalleled excellence: ISO 17025-accredited analytics, batch-specific HPSEC validation, and international cold-chain logistics.

Harness Reishi’s Millennium Legacy—Request Your NMR Report As we speak!


Reference:

  1. Časopis etnofarmakologie (2019). GLP mechanisms in most cancers apoptosis9.

  2. Sacharidové polymery (2020). Structural characterization of immunomodulatory GLPs6.

  3. Chemie jídel (2021). Ultrasonic-microwave extraction optimization3.

  4. USP-NF (2023). Polysaccharide identification/purity testing tips.

  5. Frontiers in Immunology (2024). STING pathway activation by GLPs.

1 recenze Ganoderma lucidum polysaccharide

  1. Avatar Uživatele James Oli***
    评分 4 &sol; 5

    James Oli***

    “As a health care product brand, aiherba.com’s ODM solution gives us peace of mind. They provide complete raw material traceability files. For example, the latest batch of Ganoderma lucidum triterpenoid extract can be traced from the planting to the extraction process of the organic base in Yunnan. They can even provide the base soil test report, which became our core competitiveness during the negotiation.”

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